A novel role of the CX3 CR1/CX3 CL1 system in the cross-talk between chronic lymphocytic leukemia cells and tumor microenvironment

Leukemia

Volumn 25, Issue 8, 2011, Pages 1268-1277

  Ferretti, E ^a   Bertolotto, M ^b   Deaglio, S ^c   Tripodo, C ^d   Ribatti, D ^e   Audrito, V ^c   Blengio, F ^a   Matis, S ^f   Zupo, S ^f   Rossi, D ^g   Ottonello, L ^b   Gaidano, G ^g   Malavasi, F ^c   Pistoia, V ^a   Corcione, A ^a  

^a G GASLINI INSTITUTE   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

^c UNIVERSITY OF TURIN   (Italy)

^d UNIVERSITY OF PALERMO   (Italy)

^e UNIVERSITY OF BARI   (Italy)

^f UNIVERSITY OF GENOA   (Italy)

^g UNIVERSITY OF EASTERN PIEDMONT   (Italy)

Author keywords

chemokines; chronic lymphocytic leukemia (CLL); nurselike cells (NLCs); tumor microenvironment

Indexed keywords

CHEMOKINE RECEPTOR CX3CR1; CHEMOKINE RECEPTOR CXCR4; FRACTALKINE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; STROMAL CELL DERIVED FACTOR 1; CD68 ANTIGEN, HUMAN; CHEMOKINE RECEPTOR; CX3CL1 PROTEIN, HUMAN; CX3CR1 PROTEIN, HUMAN; DIFFERENTIATION ANTIGEN; LEUKOCYTE ANTIGEN;

ADULT; AGED; ARTICLE; B LYMPHOCYTE; BLOOD CELL; BONE MARROW; CANCER PATIENT; CARCINOGENESIS; CELL ADHESION; CELL FRACTIONATION; CELL PROLIFERATION; CELL SURFACE; CHEMOTAXIS; CHRONIC LYMPHATIC LEUKEMIA; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME PHOSPHORYLATION; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; INTRACELLULAR SIGNALING; LEUKEMIA CELL; LYMPH NODE; MAJOR CLINICAL STUDY; MALE; MOLECULAR INTERACTION; NURSELIKE CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; STROMA CELL; TUMOR MICROENVIRONMENT; UPREGULATION; CELL COMMUNICATION; IMMUNOLOGY; METABOLISM; MIDDLE AGED; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; CELL COMMUNICATION; CHEMOKINE CX3CL1; CHEMOTAXIS; FEMALE; HUMANS; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; LYMPH NODES; MALE; MIDDLE AGED; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, CHEMOKINE; SIGNAL TRANSDUCTION; TUMOR MICROENVIRONMENT;

EID: 80051786984     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2011.88     Document Type: Article

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