Combined microrna-340 and ROCK1 mRNA profiling predicts tumor progression and prognosis in pediatric osteosarcoma

International Journal of Molecular Sciences

Volumn 15, Issue 1, 2014, Pages 560-573

  Cai, Haiqing ^a   Lin, Lijun ^b   Cai, Haikang ^c   Tang, Mingjie ^d   Wang, Zhigang ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

^c Orthopaedics Department   (China)

^d SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Clinicopathologic features; MicroRNA 340; Overall survival; Pediatric osteosarcoma; Progression free survival; ROCK1

Indexed keywords

MESSENGER RNA; MICRORNA; MICRORNA 340; RHO KINASE; ROCK1 PROTEIN; UNCLASSIFIED DRUG; MIRN340 MICRORNA, HUMAN; ROCK1 PROTEIN, HUMAN; TUMOR MARKER;

ADOLESCENT; ARTICLE; CANCER PROGNOSIS; CELL PROLIFERATION; CHILD; DISEASE ASSOCIATION; DOWN REGULATION; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; METASTASIS; OSTEOSARCOMA; OVERALL SURVIVAL; PROGRESSION FREE SURVIVAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR GROWTH; TUMOR VOLUME; UPREGULATION; BONE NEOPLASMS; DISEASE COURSE; DISEASE FREE SURVIVAL; GENETICS; METABOLISM; MORTALITY; PRESCHOOL CHILD; PROGNOSIS; YOUNG ADULT;

ADOLESCENT; BONE NEOPLASMS; CHILD; CHILD, PRESCHOOL; DISEASE PROGRESSION; DISEASE-FREE SURVIVAL; DOWN-REGULATION; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MICRORNAS; OSTEOSARCOMA; PROGNOSIS; RHO-ASSOCIATED KINASES; RNA, MESSENGER; TUMOR MARKERS, BIOLOGICAL; UP-REGULATION; YOUNG ADULT;

EID: 84891756862     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms15010560     Document Type: Article

References (27)

1. Broadhead, M.L., Clark, J.C., Myers, D.E. The molecular pathogenesis of osteosarcoma: A review. Sarcoma 2011, 2011, 959248.
2. Ottaviani, G., Jaffe, N. The epidemiology of osteosarcoma. Cancer Treat. Res. 2009, 152, 3-13.
3. Gorlick, R. Current concepts on the molecular biology of osteosarcoma. Cancer Treat. Res. 2009, 152, 467-478.
4. Clark, J.C., Dass, C.R., Choong, P.F. A review of clinical and molecular prognostic factors in osteosarcoma. J. Cancer Res. Clin. Oncol. 2008, 134, 281-297.
5. Papachristou, D.J., Papavassiliou, A.G. Osteosarcoma and chondrosarcoma: New signaling pathways as targets for novel therapeutic interventions. Int. J. Biochem. Cell Biol. 2007, 39, 857-862.
6. Miao, J., Wu, S., Peng, Z., Tania, M., Zhang, C. MicroRNAs in osteosarcoma: Diagnostic and therapeutic aspects. Tumor Biol. 2013, 34, 2093-2098.
7. Nana-Sinkam, S.P., Croce, C.M. Clinical applications for microRNAs in cancer. Clin. Pharmacol. Ther. 2013, 93, 98-104.
8. Shen, J., Stass, S.A., Jiang, F. MicroRNAs as potential biomarkers in human solid tumors. Cancer Lett. 2013, 329, 125-136.
9. Osman, A. MicroRNAs in health and disease-Basic science and clinical applications. Clin. Lab. 2012, 58, 393-402.
10. Amiel, J., de Pontual, L., Henrion-Caude, A. miRNA, development and disease. Adv. Genet. 2012, 80, 1-36.
11. Fabbri, M., Calore, F., Paone, A., Galli, R., Calin, G.A. Epigenetic regulation of miRNAs in cancer. Adv. Exp. Med. Biol. 2013, 754, 137-148.
12. Jones, K.B., Salah, Z., Del Mare, S., Galasso, M., Gaudio, E., Nuovo, G.J., Lovat, F., LeBlanc, K., Palatini, J., Lor Randall, R., et al. miRNA signatures associate with pathogenesis and progression of osteosarcoma. Cancer Res. 2012, 72, 1865-1877.
13. Cai, H., Lin, L., Cai, H., Tang, M., Wang, Z. Prognostic evaluation of microRNA-210 expression in pediatric osteosarcoma. Med. Oncol. 2013, 30, 499.
14. Wang, Z., Cai, H., Lin, L., Tang, M., Cai, H. Upregulated expression of microRNA-214 is linked to tumor progression and adverse prognosis in pediatric osteosarcoma. Pediatr. Blood Cancer 2013, in press.
15. Novello, C., Pazzaglia, L., Cingolani, C., Conti, A., Quattrini, I., Manara, M.C., Tognon, M., Picci, P., Benassi, M.S. miRNA expression profile in human osteosarcoma, role of miR-1 and miR-133b in proliferation and cell cycle control. Int. J. Oncol. 2013, 42, 667-675.
16. Sun, Y., Zhao, X., Zhou, Y., Hu, Y. miR-124, miR-137 and miR-340 regulate colorectal cancer growth via inhibition of the Warburg effect. Oncol. Rep. 2012, 28, 1346-1352.
17. Wu, Z.S., Wu, Q., Wang, C.Q., Wang, X.N., Huang, J., Zhao, J.J., Mao, S.S., Zhang, G.H., Xu, X.C., Zhang, N. miR-340 inhibition of breast cancer cell migration and invasion through targeting of oncoprotein c-Met. Cancer 2011, 117, 2842-2852.
18. Yao, Y., Suo, A.L., Li, Z.F., Liu, L.Y., Tian, T., Ni, L., Zhang, W.G., Nan, K.J., Song, T.S., Huang, C. MicroRNA profiling of human gastric cancer. Mol. Med. Rep. 2009, 2, 963-970.
19. Zhou, X., Wei, M., Wang, W. MicroRNA-340 suppresses osteosarcoma tumor growth and metastasis by directly targeting ROCK1. Biochem. Biophys. Res. Commun. 2013, 437, 653-658.
20. Wang, Y., Zhao, W., Fu, Q. miR-335 suppresses migration and invasion by targeting ROCK1 in osteosarcoma cells. Mol. Cell. Biochem. 2013, 384, 105-111.
21. Li, F., Jiang, Q., Shi, K.J., Luo, H., Yang, Y., Xu, C.M. RhoA modulates functional and physical interaction between ROCK1 and Erk1/2 in selenite-induced apoptosis of leukaemia cells. Cell Death Dis. 2013, 4, e708.
22. Schofield, A.V., Bernard, O. Rho-associated coiled-coil kinase (ROCK) signaling and disease. Crit. Rev. Biochem. Mol. Biol. 2013, 48, 301-316.
23. Patel, R.A., Liu, Y., Wang, B., Li, R., Sebti, S.M. Identification of novel ROCK inhibitors with anti-migratory and anti-invasive activities. Oncogene 2013, doi:10.1038/onc.2012.634.
24. Vigil, D., Kim, T.Y., Plachco, A., Garton, A.J., Castaldo, L., Pachter, J.A., Dong, H., Chen, X., Tokar, B., Campbell, S.L., et al. ROCK1 and ROCK2 are required for non-small cell lung cancer anchorage-independent growth and invasion. Cancer Res. 2012, 72, 5338-5347.
25. Wu, Y.J., Tang, Y., Li, Z.F., Li, Z., Zhao, Y., Wu, Z.J., Su Q. Expression and significance of Rac1, Pak1 and Rock1 in gastric carcinoma. Asia Pac. J. Clin. Oncol. 2013, doi:10.1111/ajco.12052.
26. Majid, S., Dar, A.A., Saini, S., Shahryari, V., Arora, S., Zaman, M.S., Chang, I., Yamamura, S., Chiyomaru, T., Fukuhara, S., et al. MicroRNA-1280 inhibits invasion and metastasis by targeting ROCK1 in bladder cancer. PLoS One 2012, 7, e46743.
27. Liu, X., Choy, E., Hornicek, F.J., Yang, S., Yang, C., Harmon, D., Mankin, H., Duan, Z. ROCK1 as a potential therapeutic target in osteosarcoma. J. Orthop. Res. 2011, 29, 1259-1266.