Globotriaosylceramide induces endothelial dysfunction in fabry disease

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 34, Issue 1, 2014, Pages 2-4

  Satoh, Kimio ^a  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR; GLOBOTRIAOSYLCERAMIDE;

ARTERY BLOOD FLOW; BLOOD VESSEL INJURY; CALCIUM TRANSPORT; CARDIOVASCULAR SYSTEM; CELL FUNCTION; CELL PROLIFERATION; CYTOKINE RELEASE; EDITORIAL; ENDOTHELIAL DYSFUNCTION; FABRY DISEASE; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN MODIFICATION; PROTEIN PROCESSING; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE; VASCULITIS; VASODILATATION;

EID: 84891751059     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.113.302744     Document Type: Editorial

References (17)

1. Shimokawa H, Tomoike H, Nabeyama S, Yamamoto H, Araki H, Nakamura M, Ishii Y, Tanaka K. Coronary artery spasm induced in atherosclerotic miniature swine. Science. 1983;221:560-562
2. Libby P, Okamoto Y, Rocha VZ, Folco E. Inflammation in atherosclerosis: Transition from theory to practice. Circ J. 2010;74:213-220
3. Satoh K, Shimokawa H, Berk BC. Cyclophilin A: Promising new target in cardiovascular therapy. Circ J. 2010;74:2249-2256
4. Vanhoutte PM. Endothelium-derived free radicals: For worse and for better. J Clin Invest. 2001;107:23-25
5. Matoba T, Shimokawa H, Nakashima M, Hirakawa Y, Mukai Y, Hirano K, Kanaide H, Takeshita A. Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in mice. J Clin Invest. 2000;106:1521-1530
6. Morikawa K, Shimokawa H, Matoba T, Kubota H, Akaike T, Talukder MA, Hatanaka M, Fujiki T, Maeda H, Takahashi S, Takeshita A. Pivotal role of Cu,Zn-superoxide dismutase in endothelium-dependent hyperpolarization. J Clin Invest. 2003;112:1871-1879
7. Takaki A, Morikawa K, Tsutsui M, Murayama Y, Tekes E, Yamagishi H, Ohashi J, Yada T, Yanagihara N, Shimokawa H. Crucial role of nitric oxide synthases system in endothelium-dependent hyperpolarization in mice. J Exp Med. 2008;205:2053-2063
8. Burgoyne JR, Prysyazhna O, Rudyk O, Eaton P. cGMP-dependent activation of protein kinase G precludes disulfide activation: Implications for blood pressure control. Hypertension. 2012;60:1301-1308
9. Rudyk O, Prysyazhna O, Burgoyne JR, Eaton P. Nitroglycerin fails to lower blood pressure in redox-dead Cys42Ser PKG1α knock-in mouse. Circulation. 2012;126:287-295
10. Burgoyne JR, Madhani M, Cuello F, Charles RL, Brennan JP, Schröder E, Browning DD, Eaton P. Cysteine redox sensor in PKGIa enables oxidantinduced activation. Science. 2007;317:1393-1397
11. Prysyazhna O, Rudyk O, Eaton P. Single atom substitution in mouse protein kinase G eliminates oxidant sensing to cause hypertension. Nat Med. 2012;18:286-290
12. Dora KA, Gallagher NT, McNeish A, Garland CJ. Modulation of endothelial cell KCa3.1 channels during endothelium-derived hyperpolarizing factor signaling in mesenteric resistance arteries. Circ Res. 2008;102:1247-1255
13. Zarate YA, Hopkin RJ. Fabry's disease. Lancet. 2008;372:1427-1435
14. Choi S, Kim JA, Na H-Y, Cho S-E, Park S, Jung S-C, Suh SH. Globotriaosylceramide induces lysosomal degradation of endothelial KCa3.1 in Fabry disease. Arterioscler Thromb Vasc Biol. 2014:34:81-89
15. Thurberg BL, Fallon JT, Mitchell R, Aretz T, Gordon RE, O'Callaghan MW. Cardiac microvascular pathology in Fabry disease: Evaluation of endomyocardial biopsies before and after enzyme replacement therapy. Circulation. 2009;119:2561-2567
16. Kalliokoski RJ, Kalliokoski KK, Sundell J, Engblom E, Penttinen M, Kantola I, Raitakari OT, Knuuti J, Nuutila P. Impaired myocardial perfusion reserve but preserved peripheral endothelial function in patients with Fabry disease. J Inherit Metab Dis. 2005;28:563-573
17. Ohashi J, Sawada A, Nakajima S, Noda K, Takaki A, Shimokawa H. Mechanisms for enhanced endothelium-derived hyperpolarizing factormediated responses in microvessels in mice. Circ J. 2012;76:1768-1779