메뉴 건너뛰기




Volumn 133, Issue 1, 2014, Pages

Genome-wide association study of lung function phenotypes in a founder population

(25)  Yao, Tsung Chieh a,b   Du, Gaixin a   Han, Lide a   Sun, Ying a   Hu, Donglei c   Yang, James J d   Mathias, Rasika e   Roth, Lindsey A c   Rafaels, Nicholas e   Thompson, Emma E a   Loisel, Dagan A a   Anderson, Rebecca a   Eng, Celeste c   Arruabarrena Orbegozo, Maitane a   Young, Melody a   Klocksieben, James M a   Anderson, Elizabeth f   Shanovich, Kathleen f   Lester, Lucille A a   Williams, L Keoki d   more..


Author keywords

FVC; GRAIL; GWAS; LASSO regression

Indexed keywords

BETA DEFENSIN; CCL18 CHEMOKINE; CHEMOKINE; STROMAL CELL DERIVED FACTOR 1; TRANSMEMBRANE ACTIVATOR AND CAML INTERACTOR; UNCLASSIFIED DRUG;

EID: 84891747469     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2013.06.018     Document Type: Article
Times cited : (54)

References (71)
  • 2
    • 78650211882 scopus 로고    scopus 로고
    • Forced vital capacity, airway obstruction and survival in a general population sample from the USA
    • P.G. Burney, and R. Hooper Forced vital capacity, airway obstruction and survival in a general population sample from the USA Thorax 66 2011 49 54
    • (2011) Thorax , vol.66 , pp. 49-54
    • Burney, P.G.1    Hooper, R.2
  • 3
    • 0029360591 scopus 로고
    • Relation of FEV1 and peripheral blood leukocyte count to total mortality. The Normative Aging Study
    • discussion 499-503
    • S.T. Weiss, M.R. Segal, D. Sparrow, and C. Wager Relation of FEV1 and peripheral blood leukocyte count to total mortality. The Normative Aging Study Am J Epidemiol 142 1995 493 498 discussion 499-503
    • (1995) Am J Epidemiol , vol.142 , pp. 493-498
    • Weiss, S.T.1    Segal, M.R.2    Sparrow, D.3    Wager, C.4
  • 4
    • 0033801133 scopus 로고    scopus 로고
    • Pulmonary function is a long-term predictor of mortality in the general population: 29-year follow-up of the Buffalo Health Study
    • H.J. Schunemann, J. Dorn, B.J. Grant, W. Winkelstein Jr., and M. Trevisan Pulmonary function is a long-term predictor of mortality in the general population: 29-year follow-up of the Buffalo Health Study Chest 118 2000 656 664
    • (2000) Chest , vol.118 , pp. 656-664
    • Schunemann, H.J.1    Dorn, J.2    Grant, B.J.3    Winkelstein, Jr.W.4    Trevisan, M.5
  • 5
    • 37449001170 scopus 로고    scopus 로고
    • Forced expiratory volume in one second: Not just a lung function test but a marker of premature death from all causes
    • R.P. Young, R. Hopkins, and T.E. Eaton Forced expiratory volume in one second: not just a lung function test but a marker of premature death from all causes Eur Respir J 30 2007 616 622
    • (2007) Eur Respir J , vol.30 , pp. 616-622
    • Young, R.P.1    Hopkins, R.2    Eaton, T.E.3
  • 7
    • 0020080186 scopus 로고
    • Genetic and environmental influences on pulmonary function in adult twins
    • H.B. Hubert, R.R. Fabsitz, M. Feinleib, and C. Gwinn Genetic and environmental influences on pulmonary function in adult twins Am Rev Respir Dis 125 1982 409 415
    • (1982) Am Rev Respir Dis , vol.125 , pp. 409-415
    • Hubert, H.B.1    Fabsitz, R.R.2    Feinleib, M.3    Gwinn, C.4
  • 8
    • 0021059061 scopus 로고
    • Lung function in an Australian population: Contributions of polygenic factors and the Pi locus to individual differences in lung function in a sample of twins
    • J.B. Gibson, N.G. Martin, J.G. Oakeshott, D.M. Rowell, and P. Clark Lung function in an Australian population: contributions of polygenic factors and the Pi locus to individual differences in lung function in a sample of twins Ann Hum Biol 10 1983 547 556
    • (1983) Ann Hum Biol , vol.10 , pp. 547-556
    • Gibson, J.B.1    Martin, N.G.2    Oakeshott, J.G.3    Rowell, D.M.4    Clark, P.5
  • 10
    • 0021924190 scopus 로고
    • Variance components analysis of forced expiration in families
    • J.A. Astemborski, T.H. Beaty, and B.H. Cohen Variance components analysis of forced expiration in families Am J Med Genet 21 1985 741 753
    • (1985) Am J Med Genet , vol.21 , pp. 741-753
    • Astemborski, J.A.1    Beaty, T.H.2    Cohen, B.H.3
  • 11
    • 0023223801 scopus 로고
    • Robust inference for variance components models in families ascertained through probands, II: Analysis of spirometric measures
    • T.H. Beaty, K.Y. Liang, S. Seerey, and B.H. Cohen Robust inference for variance components models in families ascertained through probands, II: analysis of spirometric measures Genet Epidemiol 4 1987 211 221
    • (1987) Genet Epidemiol , vol.4 , pp. 211-221
    • Beaty, T.H.1    Liang, K.Y.2    Seerey, S.3    Cohen, B.H.4
  • 13
    • 0025609658 scopus 로고
    • Path analysis of familial resemblance of pulmonary function and cigarette smoking
    • M.F. Cotch, T.H. Beaty, and B.H. Cohen Path analysis of familial resemblance of pulmonary function and cigarette smoking Am Rev Respir Dis 142 1990 1337 1343
    • (1990) Am Rev Respir Dis , vol.142 , pp. 1337-1343
    • Cotch, M.F.1    Beaty, T.H.2    Cohen, B.H.3
  • 14
    • 0025953819 scopus 로고
    • Heritability of ventilatory function in smoking and nonsmoking New Mexico Hispanics
    • D.B. Coultas, C.L. Hanis, C.A. Howard, B.J. Skipper, and J.M. Samet Heritability of ventilatory function in smoking and nonsmoking New Mexico Hispanics Am Rev Respir Dis 144 1991 770 775
    • (1991) Am Rev Respir Dis , vol.144 , pp. 770-775
    • Coultas, D.B.1    Hanis, C.L.2    Howard, C.A.3    Skipper, B.J.4    Samet, J.M.5
  • 15
    • 0027938319 scopus 로고
    • Genetic and environmental influences on pulmonary function in aging Swedish twins
    • G.E. McClearn, M. Svartengren, N.L. Pedersen, D.A. Heller, and R. Plomin Genetic and environmental influences on pulmonary function in aging Swedish twins J Gerontol 49 1994 264 268
    • (1994) J Gerontol , vol.49 , pp. 264-268
    • McClearn, G.E.1    Svartengren, M.2    Pedersen, N.L.3    Heller, D.A.4    Plomin, R.5
  • 16
    • 0029868412 scopus 로고    scopus 로고
    • Segregation analysis of two lung function indices in a random sample of young families: The Humboldt Family Study
    • Y. Chen, S.L. Horne, D.C. Rennie, and J.A. Dosman Segregation analysis of two lung function indices in a random sample of young families: the Humboldt Family Study Genet Epidemiol 13 1996 35 47
    • (1996) Genet Epidemiol , vol.13 , pp. 35-47
    • Chen, Y.1    Horne, S.L.2    Rennie, D.C.3    Dosman, J.A.4
  • 17
    • 0033922390 scopus 로고    scopus 로고
    • Evidence for major genes influencing pulmonary function in the NHLBI family heart study
    • J.B. Wilk, L. Djousse, D.K. Arnett, S.S. Rich, M.A. Province, and S.C. Hunt et al. Evidence for major genes influencing pulmonary function in the NHLBI family heart study Genet Epidemiol 19 2000 81 94
    • (2000) Genet Epidemiol , vol.19 , pp. 81-94
    • Wilk, J.B.1    Djousse, L.2    Arnett, D.K.3    Rich, S.S.4    Province, M.A.5    Hunt, S.C.6
  • 18
    • 0033678658 scopus 로고    scopus 로고
    • Familial aggregation and heritability of asthma-associated quantitative traits in a population-based sample of nuclear families
    • L.J. Palmer, P.R. Burton, A.L. James, A.W. Musk, and W.O. Cookson Familial aggregation and heritability of asthma-associated quantitative traits in a population-based sample of nuclear families Eur J Hum Genet 8 2000 853 860
    • (2000) Eur J Hum Genet , vol.8 , pp. 853-860
    • Palmer, L.J.1    Burton, P.R.2    James, A.L.3    Musk, A.W.4    Cookson, W.O.5
  • 19
    • 0035021432 scopus 로고    scopus 로고
    • Familial aggregation and heritability of adult lung function: Results from the Busselton Health Study
    • L.J. Palmer, M.W. Knuiman, M.L. Divitini, P.R. Burton, A.L. James, and H.C. Bartholomew et al. Familial aggregation and heritability of adult lung function: results from the Busselton Health Study Eur Respir J 17 2001 696 702
    • (2001) Eur Respir J , vol.17 , pp. 696-702
    • Palmer, L.J.1    Knuiman, M.W.2    Divitini, M.L.3    Burton, P.R.4    James, A.L.5    Bartholomew, H.C.6
  • 20
    • 0034753277 scopus 로고    scopus 로고
    • The genetic dissection of complex traits in a founder population
    • C. Ober, M. Abney, and M.S. McPeek The genetic dissection of complex traits in a founder population Am J Hum Genet 69 2001 1068 1079
    • (2001) Am J Hum Genet , vol.69 , pp. 1068-1079
    • Ober, C.1    Abney, M.2    McPeek, M.S.3
  • 21
    • 73349143302 scopus 로고    scopus 로고
    • Genome-wide association study identifies five loci associated with lung function
    • E. Repapi, I. Sayers, L.V. Wain, P.R. Burton, T. Johnson, and M. Obeidat et al. Genome-wide association study identifies five loci associated with lung function Nat Genet 42 2010 36 44
    • (2010) Nat Genet , vol.42 , pp. 36-44
    • Repapi, E.1    Sayers, I.2    Wain, L.V.3    Burton, P.R.4    Johnson, T.5    Obeidat, M.6
  • 22
    • 73349111257 scopus 로고    scopus 로고
    • Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function
    • D.B. Hancock, M. Eijgelsheim, J.B. Wilk, S.A. Gharib, L.R. Loehr, and K.D. Marciante et al. Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function Nat Genet 42 2010 45 52
    • (2010) Nat Genet , vol.42 , pp. 45-52
    • Hancock, D.B.1    Eijgelsheim, M.2    Wilk, J.B.3    Gharib, S.A.4    Loehr, L.R.5    Marciante, K.D.6
  • 23
    • 80055008094 scopus 로고    scopus 로고
    • Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function
    • M. Soler Artigas, D.W. Loth, L.V. Wain, S.A. Gharib, M. Obeidat, and W. Tang et al. Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function Nat Genet 43 2011 1082 1090
    • (2011) Nat Genet , vol.43 , pp. 1082-1090
    • Soler Artigas, M.1    Loth, D.W.2    Wain, L.V.3    Gharib, S.A.4    Obeidat, M.5    Tang, W.6
  • 25
    • 55549147191 scopus 로고    scopus 로고
    • Personal genomes: The case of the missing heritability
    • B. Maher Personal genomes: the case of the missing heritability Nature 456 2008 18 21
    • (2008) Nature , vol.456 , pp. 18-21
    • Maher, B.1
  • 27
    • 77952557918 scopus 로고    scopus 로고
    • Missing heritability and strategies for finding the underlying causes of complex disease
    • E.E. Eichler, J. Flint, G. Gibson, A. Kong, S.M. Leal, and J.H. Moore et al. Missing heritability and strategies for finding the underlying causes of complex disease Nat Rev Genet 11 2010 446 450
    • (2010) Nat Rev Genet , vol.11 , pp. 446-450
    • Eichler, E.E.1    Flint, J.2    Gibson, G.3    Kong, A.4    Leal, S.M.5    Moore, J.H.6
  • 28
    • 77954140531 scopus 로고    scopus 로고
    • Common SNPs explain a large proportion of the heritability for human height
    • J. Yang, B. Benyamin, B.P. McEvoy, S. Gordon, A.K. Henders, and D.R. Nyholt et al. Common SNPs explain a large proportion of the heritability for human height Nat Genet 42 2010 565 569
    • (2010) Nat Genet , vol.42 , pp. 565-569
    • Yang, J.1    Benyamin, B.2    McEvoy, B.P.3    Gordon, S.4    Henders, A.K.5    Nyholt, D.R.6
  • 30
    • 42649092874 scopus 로고    scopus 로고
    • Identification of ten loci associated with height highlights new biological pathways in human growth
    • G. Lettre, A.U. Jackson, C. Gieger, F.R. Schumacher, S.I. Berndt, and S. Sanna et al. Identification of ten loci associated with height highlights new biological pathways in human growth Nat Genet 40 2008 584 591
    • (2008) Nat Genet , vol.40 , pp. 584-591
    • Lettre, G.1    Jackson, A.U.2    Gieger, C.3    Schumacher, F.R.4    Berndt, S.I.5    Sanna, S.6
  • 31
    • 42649139571 scopus 로고    scopus 로고
    • Genome-wide association analysis identifies 20 loci that influence adult height
    • M.N. Weedon, H. Lango, C.M. Lindgren, C. Wallace, D.M. Evans, and M. Mangino et al. Genome-wide association analysis identifies 20 loci that influence adult height Nat Genet 40 2008 575 583
    • (2008) Nat Genet , vol.40 , pp. 575-583
    • Weedon, M.N.1    Lango, H.2    Lindgren, C.M.3    Wallace, C.4    Evans, D.M.5    Mangino, M.6
  • 32
    • 42649123990 scopus 로고    scopus 로고
    • Sizing up human height variation
    • P.M. Visscher Sizing up human height variation Nat Genet 40 2008 489 490
    • (2008) Nat Genet , vol.40 , pp. 489-490
    • Visscher, P.M.1
  • 33
    • 0031954852 scopus 로고    scopus 로고
    • The genetics of asthma. Mapping genes for complex traits in founder populations
    • discussion 108-10
    • C. Ober, and N.J. Cox The genetics of asthma. Mapping genes for complex traits in founder populations Clin Exp Allergy 28 Suppl 1 1998 101 105 discussion 108-10
    • (1998) Clin Exp Allergy , vol.28 , Issue.SUPPL. 1 , pp. 101-105
    • Ober, C.1    Cox, N.J.2
  • 34
    • 31744449136 scopus 로고    scopus 로고
    • The sex-specific genetic architecture of quantitative traits in humans
    • L.A. Weiss, L. Pan, M. Abney, and C. Ober The sex-specific genetic architecture of quantitative traits in humans Nat Genet 38 2006 218 222
    • (2006) Nat Genet , vol.38 , pp. 218-222
    • Weiss, L.A.1    Pan, L.2    Abney, M.3    Ober, C.4
  • 35
    • 0004041298 scopus 로고
    • Johns Hopkins University Press Baltimore, Md
    • J.A. Hostetler Hutterite society 1974 Johns Hopkins University Press Baltimore, Md
    • (1974) Hutterite Society
    • Hostetler, J.A.1
  • 37
    • 0036201581 scopus 로고    scopus 로고
    • Quantitative trait homozygosity and association mapping and empirical genome-wide significance in large complex pedigrees: Fasting serum insulin level in the Hutterites
    • M. Abney, C. Ober, and M.S. McPeek Quantitative trait homozygosity and association mapping and empirical genome-wide significance in large complex pedigrees: fasting serum insulin level in the Hutterites Am J Hum Genet 70 2002 920 934
    • (2002) Am J Hum Genet , vol.70 , pp. 920-934
    • Abney, M.1    Ober, C.2    McPeek, M.S.3
  • 38
    • 84859260926 scopus 로고    scopus 로고
    • The combination of a genome-wide association study of lymphocyte count and analysis of gene expression data reveals novel asthma candidate genes
    • D.A. Cusanovich, C. Billstrand, X. Zhou, C. Chavarria, S. De Leon, and K. Michelini et al. The combination of a genome-wide association study of lymphocyte count and analysis of gene expression data reveals novel asthma candidate genes Hum Mol Genet 21 2012 2111 2123
    • (2012) Hum Mol Genet , vol.21 , pp. 2111-2123
    • Cusanovich, D.A.1    Billstrand, C.2    Zhou, X.3    Chavarria, C.4    De Leon, S.5    Michelini, K.6
  • 39
    • 42249103640 scopus 로고    scopus 로고
    • Effect of variation in CHI3L1 on serum YKL-40 level, asthma risk, and lung function
    • C. Ober, Z. Tan, Y. Sun, J.D. Possick, L. Pan, and R. Nicolae et al. Effect of variation in CHI3L1 on serum YKL-40 level, asthma risk, and lung function N Engl J Med 358 2008 1682 1691
    • (2008) N Engl J Med , vol.358 , pp. 1682-1691
    • Ober, C.1    Tan, Z.2    Sun, Y.3    Possick, J.D.4    Pan, L.5    Nicolae, R.6
  • 40
    • 0033759713 scopus 로고    scopus 로고
    • A second-generation genomewide screen for asthma-susceptibility alleles in a founder population
    • C. Ober, A. Tsalenko, R. Parry, and N.J. Cox A second-generation genomewide screen for asthma-susceptibility alleles in a founder population Am J Hum Genet 67 2000 1154 1162
    • (2000) Am J Hum Genet , vol.67 , pp. 1154-1162
    • Ober, C.1    Tsalenko, A.2    Parry, R.3    Cox, N.J.4
  • 43
    • 11244250720 scopus 로고    scopus 로고
    • Testing for Hardy-Weinberg equilibrium in samples with related individuals
    • C. Bourgain, M. Abney, D. Schneider, C. Ober, and M.S. McPeek Testing for Hardy-Weinberg equilibrium in samples with related individuals Genetics 168 2004 2349 2361
    • (2004) Genetics , vol.168 , pp. 2349-2361
    • Bourgain, C.1    Abney, M.2    Schneider, D.3    Ober, C.4    McPeek, M.S.5
  • 44
    • 0035023261 scopus 로고    scopus 로고
    • Broad and narrow heritabilities of quantitative traits in a founder population
    • M. Abney, M.S. McPeek, and C. Ober Broad and narrow heritabilities of quantitative traits in a founder population Am J Hum Genet 68 2001 1302 1307
    • (2001) Am J Hum Genet , vol.68 , pp. 1302-1307
    • Abney, M.1    McPeek, M.S.2    Ober, C.3
  • 45
    • 0032714352 scopus 로고    scopus 로고
    • Genomic control for association studies
    • B. Devlin, and K. Roeder Genomic control for association studies Biometrics 55 1999 997 1004
    • (1999) Biometrics , vol.55 , pp. 997-1004
    • Devlin, B.1    Roeder, K.2
  • 46
    • 85194972808 scopus 로고    scopus 로고
    • Regression shrinkage and selectionv ia the lasso
    • R. Tibshirani Regression shrinkage and selectionv ia the lasso J R Stat Soc Ser B 58 1996 267 288
    • (1996) J R Stat Soc ser B , vol.58 , pp. 267-288
    • Tibshirani, R.1
  • 47
    • 82455215082 scopus 로고    scopus 로고
    • Evaluation of a LASSO regression approach on the unrelated samples of Genetic Analysis Workshop 17
    • W. Guo, R. Elston, and X. Zhu Evaluation of a LASSO regression approach on the unrelated samples of Genetic Analysis Workshop 17 BMC Proc 5 2011 S12
    • (2011) BMC Proc , vol.5 , pp. 12
    • Guo, W.1    Elston, R.2    Zhu, X.3
  • 48
    • 62549115747 scopus 로고    scopus 로고
    • Genome-wide association analysis by lasso penalized logistic regression
    • T.T. Wu, Y.F. Chen, T. Hastie, E. Sobel, and K. Lange Genome-wide association analysis by lasso penalized logistic regression Bioinformatics 25 2009 714 721
    • (2009) Bioinformatics , vol.25 , pp. 714-721
    • Wu, T.T.1    Chen, Y.F.2    Hastie, T.3    Sobel, E.4    Lange, K.5
  • 49
    • 77950537175 scopus 로고    scopus 로고
    • Regularization paths for generalized linear models via coordinate descent
    • J. Friedman, T. Hastie, and R. Tibshirani Regularization paths for generalized linear models via coordinate descent J Stat Softw 33 2010 1 22
    • (2010) J Stat Softw , vol.33 , pp. 1-22
    • Friedman, J.1    Hastie, T.2    Tibshirani, R.3
  • 50
    • 67651205715 scopus 로고    scopus 로고
    • Identifying relationships among genomic disease regions: Predicting genes at pathogenic SNP associations and rare deletions
    • S. Raychaudhuri, R.M. Plenge, E.J. Rossin, A.C. Ng, S.M. Purcell, and P. Sklar et al. Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions PLoS Genet 5 2009 e1000534
    • (2009) PLoS Genet , vol.5 , pp. 1000534
    • Raychaudhuri, S.1    Plenge, R.M.2    Rossin, E.J.3    Ng, A.C.4    Purcell, S.M.5    Sklar, P.6
  • 51
    • 65949107547 scopus 로고    scopus 로고
    • Common genetic variation and human traits
    • D.B. Goldstein Common genetic variation and human traits N Engl J Med 360 2009 1696 1698
    • (2009) N Engl J Med , vol.360 , pp. 1696-1698
    • Goldstein, D.B.1
  • 52
    • 65949124249 scopus 로고    scopus 로고
    • Genomewide association studies-illuminating biologic pathways
    • J.N. Hirschhorn Genomewide association studies-illuminating biologic pathways N Engl J Med 360 2009 1699 1701
    • (2009) N Engl J Med , vol.360 , pp. 1699-1701
    • Hirschhorn, J.N.1
  • 53
    • 65949099120 scopus 로고    scopus 로고
    • Genetic risk prediction-are we there yet?
    • P. Kraft, and D.J. Hunter Genetic risk prediction-are we there yet? N Engl J Med 360 2009 1701 1703
    • (2009) N Engl J Med , vol.360 , pp. 1701-1703
    • Kraft, P.1    Hunter, D.J.2
  • 55
    • 79958131369 scopus 로고    scopus 로고
    • Novel method to estimate the phenotypic variation explained by genome-wide association studies reveals large fraction of the missing heritability
    • Z. Kutalik, J. Whittaker, D. Waterworth, J.S. Beckmann, and S. Bergmann Novel method to estimate the phenotypic variation explained by genome-wide association studies reveals large fraction of the missing heritability Genet Epidemiol 35 2011 341 349
    • (2011) Genet Epidemiol , vol.35 , pp. 341-349
    • Kutalik, Z.1    Whittaker, J.2    Waterworth, D.3    Beckmann, J.S.4    Bergmann, S.5
  • 56
    • 79952489475 scopus 로고    scopus 로고
    • Estimating missing heritability for disease from genome-wide association studies
    • S.H. Lee, N.R. Wray, M.E. Goddard, and P.M. Visscher Estimating missing heritability for disease from genome-wide association studies Am J Hum Genet 88 2011 294 305
    • (2011) Am J Hum Genet , vol.88 , pp. 294-305
    • Lee, S.H.1    Wray, N.R.2    Goddard, M.E.3    Visscher, P.M.4
  • 57
    • 78649317608 scopus 로고    scopus 로고
    • Predicting genetic predisposition in humans: The promise of whole-genome markers
    • G. de los Campos, D. Gianola, and D.B. Allison Predicting genetic predisposition in humans: the promise of whole-genome markers Nat Rev Genet 11 2010 880 886
    • (2010) Nat Rev Genet , vol.11 , pp. 880-886
    • De Los Campos, G.1    Gianola, D.2    Allison, D.B.3
  • 59
    • 77953301125 scopus 로고    scopus 로고
    • Review: Defensins and cathelicidins in lung immunity
    • T. Tecle, S. Tripathi, and K.L. Hartshorn Review: defensins and cathelicidins in lung immunity Innate Immun 16 2010 151 159
    • (2010) Innate Immun , vol.16 , pp. 151-159
    • Tecle, T.1    Tripathi, S.2    Hartshorn, K.L.3
  • 61
    • 79960469576 scopus 로고    scopus 로고
    • Increased expression of beta-defensin 1 (DEFB1) in chronic obstructive pulmonary disease
    • E. Andresen, G. Gunther, J. Bullwinkel, C. Lange, and H. Heine Increased expression of beta-defensin 1 (DEFB1) in chronic obstructive pulmonary disease PLoS One 6 2011 e21898
    • (2011) PLoS One , vol.6 , pp. 21898
    • Andresen, E.1    Gunther, G.2    Bullwinkel, J.3    Lange, C.4    Heine, H.5
  • 62
    • 79953145166 scopus 로고    scopus 로고
    • A polymorphism in the 5′ UTR of the DEFB1 gene is associated with the lung phenotype in F508del homozygous Italian cystic fibrosis patients
    • S. Crovella, L. Segat, A. Amato, E. Athanasakis, V. Bezzerri, and C. Braggion et al. A polymorphism in the 5′ UTR of the DEFB1 gene is associated with the lung phenotype in F508del homozygous Italian cystic fibrosis patients Clin Chem Lab Med 49 2011 49 54
    • (2011) Clin Chem Lab Med , vol.49 , pp. 49-54
    • Crovella, S.1    Segat, L.2    Amato, A.3    Athanasakis, E.4    Bezzerri, V.5    Braggion, C.6
  • 63
    • 0031203966 scopus 로고    scopus 로고
    • A novel human CC chemokine PARC that is most homologous to macrophage-inflammatory protein-1 alpha/LD78 alpha and chemotactic for T lymphocytes, but not for monocytes
    • K. Hieshima, T. Imai, M. Baba, K. Shoudai, K. Ishizuka, and T. Nakagawa et al. A novel human CC chemokine PARC that is most homologous to macrophage-inflammatory protein-1 alpha/LD78 alpha and chemotactic for T lymphocytes, but not for monocytes J Immunol 159 1997 1140 1149
    • (1997) J Immunol , vol.159 , pp. 1140-1149
    • Hieshima, K.1    Imai, T.2    Baba, M.3    Shoudai, K.4    Ishizuka, K.5    Nakagawa, T.6
  • 64
    • 78649747976 scopus 로고    scopus 로고
    • The chemokine CCL18 generates adaptive regulatory T cells from memory CD4+ T cells of healthy but not allergic subjects
    • Y. Chang, P. de Nadai, I. Azzaoui, O. Morales, N. Delhem, and H. Vorng et al. The chemokine CCL18 generates adaptive regulatory T cells from memory CD4+ T cells of healthy but not allergic subjects FASEB J 24 2010 5063 5072
    • (2010) FASEB J , vol.24 , pp. 5063-5072
    • Chang, Y.1    De Nadai, P.2    Azzaoui, I.3    Morales, O.4    Delhem, N.5    Vorng, H.6
  • 65
    • 46349104684 scopus 로고    scopus 로고
    • Interaction between a novel TGFB1 haplotype and CFTR genotype is associated with improved lung function in cystic fibrosis
    • L.A. Bremer, S.M. Blackman, L.L. Vanscoy, K.E. McDougal, A. Bowers, and K.M. Naughton et al. Interaction between a novel TGFB1 haplotype and CFTR genotype is associated with improved lung function in cystic fibrosis Hum Mol Genet 17 2008 2228 2237
    • (2008) Hum Mol Genet , vol.17 , pp. 2228-2237
    • Bremer, L.A.1    Blackman, S.M.2    Vanscoy, L.L.3    McDougal, K.E.4    Bowers, A.5    Naughton, K.M.6
  • 69
    • 84855978239 scopus 로고    scopus 로고
    • Rare mutations in TNFRSF13B increase the risk of asthma symptoms in Swedish children
    • M. Janzi, E. Melen, I. Kull, M. Wickman, and L. Hammarstrom Rare mutations in TNFRSF13B increase the risk of asthma symptoms in Swedish children Genes Immun 13 2012 59 65
    • (2012) Genes Immun , vol.13 , pp. 59-65
    • Janzi, M.1    Melen, E.2    Kull, I.3    Wickman, M.4    Hammarstrom, L.5
  • 70
    • 78049345408 scopus 로고    scopus 로고
    • A novel insight into adaptive immunity in chronic obstructive pulmonary disease: B cell activating factor belonging to the tumor necrosis factor family
    • F. Polverino, S. Baraldo, E. Bazzan, S. Agostini, G. Turato, and F. Lunardi et al. A novel insight into adaptive immunity in chronic obstructive pulmonary disease: B cell activating factor belonging to the tumor necrosis factor family Am J Respir Crit Care Med 182 2010 1011 1019
    • (2010) Am J Respir Crit Care Med , vol.182 , pp. 1011-1019
    • Polverino, F.1    Baraldo, S.2    Bazzan, E.3    Agostini, S.4    Turato, G.5    Lunardi, F.6
  • 71
    • 67649729589 scopus 로고    scopus 로고
    • Genome-wide association study of plasma lipoprotein(a) levels identifies multiple genes on chromosome 6q
    • C. Ober, A.S. Nord, E.E. Thompson, L. Pan, Z. Tan, and D. Cusanovich et al. Genome-wide association study of plasma lipoprotein(a) levels identifies multiple genes on chromosome 6q J Lipid Res 50 2009 798 806
    • (2009) J Lipid Res , vol.50 , pp. 798-806
    • Ober, C.1    Nord, A.S.2    Thompson, E.E.3    Pan, L.4    Tan, Z.5    Cusanovich, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.