MEK1-RSK2 contributes to hedgehog signaling by stabilizing GLI2 transcription factor and inhibiting ubiquitination

Oncogene

Volumn 33, Issue 1, 2014, Pages 65-73

  Liu, Z ^a,b   Li, T ^c   Reinhold, M I ^a,d   Naski, M C ^a,e  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b UNIVERSITY OF TEXAS   (United States)

^c ZHEJIANG NORMAL UNIVERSITY   (China)

^d GRAND VALLEY STATE UNIVERSITY   (United States)

^e St Mary's Health Care ^*  (United States)

Author keywords

GLI2; Hedgehog; MEK1; multiple myeloma; RSK2; ubiquitination

Indexed keywords

MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; PROTEIN KINASE; RSK2 PROTEIN; TRANSCRIPTION FACTOR GLI2; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; HALF LIFE TIME; HEDGEHOG; HUMAN; HUMAN CELL; MULTIPLE MYELOMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; UBIQUITINATION;

ERINACEIDAE;

EID: 84891743030     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2012.544     Document Type: Article

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