Nonpolymeric surface-coated iron oxide nanoparticles for in vivo molecular imaging: Biodegradation, biocompatibility, and multiplatform

Journal of Nuclear Medicine

Volumn 54, Issue 11, 2013, Pages 1974-1980

  Lee, Chang Moon ^a   Cheong, Su Jin ^b   Kim, Eun Mi ^b   Lim, Seok Tae ^b   Jeong, Yong Yeon ^c   Sohn, Myung Hee ^b   Jeong, Hwan Jeong ^b  

^a Chonnam National University   (South Korea)

^b Chonbuk National University Medical School   (South Korea)

^c Chonnam National University Medical School   (South Korea)

Author keywords

ATP; Iron oxide nanoparticle; Molecular imaging; Multiplatform; Tumor imaging

Indexed keywords

ADENOSINE TRIPHOSPHATE; GLUCONIC ACID SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE CONJUGATE; IODINE SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE I 125; NANOPARTICLE; RADIOPHARMACEUTICAL AGENT; SCATTER FACTOR RECEPTOR; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE; UNCLASSIFIED DRUG; BIOMATERIAL; DIAGNOSTIC AGENT; FERRIC ION; FERRIC OXIDE; GLUCONIC ACID; IRON OXIDE NANOPARTICLE; LIGAND;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCOMPATIBILITY; BIODEGRADATION; CHEMICAL MODIFICATION; CONJUGATION; CONTROLLED STUDY; IN VITRO STUDY; IN VIVO STUDY; MATERIAL COATING; MOLECULAR IMAGING; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SCANNER; PHAGOCYTOSIS; PRIORITY JOURNAL; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SURFACE PROPERTY; TUMOR MODEL; ANIMAL; CHEMISTRY; HUMAN; MAGNET; METABOLISM; METHODOLOGY; MULTIMODAL IMAGING; MULTIPLATFORM; TUMOR CELL LINE; TUMOR IMAGING; DIAGNOSTIC USE; PROCEDURES;

ATP; IRON OXIDE NANOPARTICLE; MOLECULAR IMAGING; MULTIPLATFORM; TUMOR IMAGING;

ADENOSINE TRIPHOSPHATE; ANIMALS; CELL LINE, TUMOR; COATED MATERIALS, BIOCOMPATIBLE; FERRIC COMPOUNDS; GLUCONATES; HUMANS; LIGANDS; MAGNETS; MICE; MOLECULAR IMAGING; MULTIMODAL IMAGING; NANOPARTICLES; SURFACE PROPERTIES;

EID: 84891702929     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.113.122267     Document Type: Article

References (40)

1. Gupta AK, Gupta M. Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications. Biomaterials. 2005;26:3995-4021.
2. Lee CM, Jeong HJ, Lim ST, Sohn MH, Kim DW. Synthesis of iron oxide nanoparticles with control over shape using imidazolium-based ionic liquids. ACS Appl Mater Interfaces. 2010;2:756-759.
3. Lu AH, Salabas EL, Schüth F. Magnetic nanoparticles: synthesis, protection, functionalization, and application. Angew Chem Int Ed Engl. 2007;46:1222-1244.
4. Lin MM, Kim HH, Kim H, Dobson J, Kim do K. Surface activation and targeting strategies of superparamagnetic iron oxide nanoparticles in cancer-oriented diagnosis and therapy. Nanomedicine (Lond). 2010;5:109-133.
5. Shubayev VI, Pisanic TR, Jin S. Magnetic nanoparticles for theragnostics. Adv Drug Deliv Rev. 2009;61:467-477.
6. Gupta AK, Naregalkar RR, Vaidya VD, Gupta M. Recent advances on surface engineering of magnetic iron oxide nanoparticles and their biomedical applications. Nanomedicine (Lond). 2007;2:23-39.
7. Liong M, Lu J, Kovochich M, et al. Multifunctional inorganic nanoparticles for imaging, targeting, and drug delivery. ACS Nano. 2008;2:889-896.
8. Choi JS, Park JC, Nah H, et al. Hybrid nanoparticle probe for dual-modality positron emission tomography and magnetic resonance imaging. Angew Chem Int Ed Engl. 2008;47:6259-6262.
9. Shi Z, Neoh KG, Kang ET, et al. (Carboxymethyl)chitosan-modified superparamagnetic iron oxide nanoparticles for magnetic resonance imaging of stem cells. ACS Appl Mater Interfaces. 2009;1:328-335.
10. Pittet MJ, Swirski FK, Reynolds F, Josephson L, Weissleder R. Labeling of immune cells for in vivo imaging using magnetofluorescent nanoparticles. Nat Protoc. 2006;1:73-79.
11. Lee CM, Jeong HJ, Kim EM, et al. Synthesis and characterization of iron oxide nanoparticles decorated with carboxymethyl curdlan. Macromol Res. 2009;17: 133-136.
12. Kojima H, Mukai Y, Yoshikawa M, et al. Simple PEG conjugation of SPIO via an Au-S bond improves its tumor targeting potency as a novel MR tumor imaging agent. Bioconjug Chem. 2010;21:1026-1031.
13. Makhluf SB, Abu-Mukh R, Rubinstein S, Breitbart H, Gedanken A. Modified PVA-Fe3O4 nanoparticles as protein carriers into sperm cells. Small. 2008;4: 1453-1458.
14. Lee H, Yu MK, Park S, et al. Thermally cross-linked superparamagnetic iron oxide nanoparticles: synthesis and application as a dual imaging probe for cancer in vivo. J Am Chem Soc. 2007;129:12739-12745.
15. Oksendal AN, Hals PA. Biodistribution and toxicity of MR imaging contrast media. J Magn Reson Imaging. 1993;3:157-165.
16. Kean T, Thanou M. Biodegradation, biodistribution and toxicity of chitosan. Adv Drug Deliv Rev. 2010;62:3-11.
17. Jiskoot W, van Schie RM, Carstens MG, Schellekens H. Immunological risk of injectable drug delivery systems. Pharm Res. 2009;26:1303-1314.
18. Lee H, Lee E, Kim DK, Jang NK, Jeong YY, Jon S. Antibiofouling polymer-coated superparamagnetic iron oxide nanoparticles as potential magnetic resonance contrast agents for in vivo cancer imaging. J Am Chem Soc. 2006;128:7383-7389.
19. Thorek DL, Tsourkas A. Size, charge and concentration dependent uptake of iron oxide particles by non-phagocytic cells. Biomaterials. 2008;29:3583-3590.
20. Nel A, Xia T, Mädler L, Li N. Toxic potential of materials at the nanolevel. Science. 2006;311:622-627.
21. Lalatonne Y, Paris C, Serfaty JM, Weinmann P, Lecouvey M, Motte L. Bisphosphonates-ultra small superparamagnetic iron oxide nanoparticles: a platform towards diagnosis and therapy. Chem Commun (Camb). 2008;14:2553-2555.
22. Bae JE, Huh MI, Ryu BK, et al. The effect of static magnetic fields on the aggregation and cytotoxicity of magnetic nanoparticles. Biomaterials. 2011;32: 9401-9414.
23. Lévy M, Luciani N, Alloyeau D, et al. Long term in vivo biotransformation of iron oxide nanoparticles. Biomaterials. 2011;32:3988-3999.
24. Lee CM, Jeong HJ, Cheong SJ, et al. Prostate cancer-targeted imaging using magnetofluorescent polymeric nanoparticles functionalized with bombesin. Pharm Res. 2010;27:712-721.
25. Wilkinson K, Ekstrand-Hammarström B, Ahlinder L, et al. Visualization of custom-tailored iron oxide nanoparticles chemistry, uptake, and toxicity. Nanoscale. 2012;4:7383-7393.
26. Pazik R, Andersson R, Kepinski L, Nedelec JM, Kessler VG, Seisenbaeva GA. Surface functionalization of the metal oxide nanoparticles with biologically active molecules containing phosphonate moieties: case study of BaTiO3. J Phys Chem C. 2011;115:9850-9860.
27. Li Z, Tan B, Allix M, Cooper AI, Rosseinsky MJ. Direct coprecipitation route to monodisperse dual-functionalized magnetic iron oxide nanocrystals without size selection. Small. 2008;4:231-239.
28. Mahmoudi M, Simchi A, Imani M, Milani AS, Stroeve P. Optimal design and characterization of superparamagnetic iron oxide nanoparticles coated with polyvinyl alcohol for targeted delivery and imaging. J Phys Chem B. 2008;112: 14470-14481.
29. Wang J, Chen Y, Chen B, et al. Pharmacokinetic parameters and tissue distribution of magnetic Fe3O4 nanoparticles in mice. Int J Nanomedicine. 2010;5:861-866.
30. Lunov O, Syrovets T, Röcker C, et al. Lysosomal degradation of the carboxydextran shell of coated superparamagnetic iron oxide nanoparticles and the fate of professional phagocytes. Biomaterials. 2010;31:9015-9022.
31. Briley-Saebø K, Bjørnerud A, Grant D, Ahlstrom H, Berg T, Kindberg GM. Hepatic cellular distribution and degradation of iron oxide nanoparticles following single intravenous injection in rats: implications for magnetic resonance imaging. Cell Tissue Res. 2004;316:315-323.
32. Briley-Saebø K, Hustvedt SO, Haldorsen A, Bjørnerud A. Long-term imaging effects in rat liver after a single injection of an iron oxide nanoparticle based MR contrast agent. J Magn Imaging. 2004;20:622-631.
33. Lee CM, Jeong HJ, Kim EM, et al. Superparamagnetic iron oxide nanoparticles as a dual imaging probe for targeting hepatocytes in vivo. Magn Reson Med. 2009;62:1440-1446.
34. Lee CM, Jeong HJ, Kim SL, et al. SPION-loaded chitosan-linoleic acid nanoparticles to target hepatocytes. Int J Pharm. 2009;371:163-169.
35. Lee CM, Jang DR, Cheong SJ, et al. Surface engineering of QDots for in vivo imaging. Nanotechnology. 2010;21:285102.
36. Martin TA, Jiang WG. Hepatocyte growth factor and its receptor signalling complex as targets in cancer therapy. Anticancer Agents Med Chem. 2010;10: 2-6.
37. Parr C, Jiang WG. Hepatocyte growth factor activators, inhibitors and antagonists and their implication in cancer intervention. Histol Histopathol. 2001;16: 251-268.
38. Moriyama T, Kataoka H, Koono M, Wakisaka S. Expression of hepatocyte growth factor/scatter factor and its receptor c-Met in brain tumors: evidence for a role in progression of astrocytic tumors. Int J Mol Med. 1999;3:531-536.
39. Kim EM, Park EH, Cheong SJ, et al. In vivo imaging of mesenchymal-epithelial transition factor (c-Met) expression using an optical imaging system. Bioconjug Chem. 2009;20:1299-1306.
40. Kim EM, Park EH, Cheong SJ, et al. Characterization, biodistribution and smallanimal SPECT of I-125-labeled c-Met binding peptide in mice bearing c-Met receptor tyrosine kinase-positive tumor xenografts. Nucl Med Biol. 2009;36: 371-378.