Expression of HDAC9 in lung cancer - potential role in lung carcinogenesis

International Journal of Clinical and Experimental Pathology

Volumn 7, Issue 1, 2014, Pages 213-220

  Okudela, Koji ^a   Mitsui, Hideaki ^a   Suzuki, Takehisa ^a   Woo, Tetsukan ^a   Tateishi, Yoko ^a   Umeda, Shigeaki ^a   Saito, Yuichi ^a   Tajiri, Michihiko ^b   Masuda, Munetaka ^a   Ohashi, Kenichi ^a  

^a YOKOHAMA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b Kanagawa Prefectural Cardiovascular and Respiratory Center Hospital   (Japan)

Author keywords

HDAC9; KRAS; Lung cancer

Indexed keywords

HDAC9 PROTEIN, HUMAN; HISTONE DEACETYLASE; REPRESSOR PROTEIN;

ARTICLE; CARCINOGENESIS; CARCINOMA; DISEASE COURSE; DOWN REGULATION; GENETIC TRANSFECTION; HDAC9; HUMAN; IMMUNOHISTOCHEMISTRY; KRAS; LUNG CANCER; LUNG TUMOR; METABOLISM; PATHOLOGY; POLYMERASE CHAIN REACTION; TUMOR CELL LINE; WESTERN BLOTTING;

HDAC9; KRAS; LUNG CANCER;

BLOTTING, WESTERN; CARCINOGENESIS; CARCINOMA; CELL LINE, TUMOR; DISEASE PROGRESSION; DOWN-REGULATION; HISTONE DEACETYLASES; HUMANS; IMMUNOHISTOCHEMISTRY; LUNG NEOPLASMS; POLYMERASE CHAIN REACTION; REPRESSOR PROTEINS; TRANSFECTION;

EID: 84891700846     PISSN: None     EISSN: 19362625     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Hoffman PC, Cohen EE, Masters GA, Haraf DJ, Mauer AM, Rudin CM, Krauss SA, Huo D and Vokes EE. Carboplatin plus vinorelbine with concomitant radiation therapy in advanced non-small cell lung cancer: a phase I study. Lung Cancer 2002; 38: 65-71.
2. Spira A and Ettinger DS. Multidisciplinary management of lung cancer. N Engl J Med 2004; 350: 379-392.
3. Okudela K, Woo T and Kitamura H. KRAS gene mutations in lung cancer: particulars established and issues unresolved. Pathol Int 2010; 60: 651-660.
4. Woo T, Okudela K, Yazawa T, Wada N, Ogawa N, Ishiwa N, Tajiri M, Rino Y, Kitamura H and Masuda M. Prognostic value of KRAS mutations and Ki-67 expression in stage I lung adenocarcinomas. Lung Cancer 2009; 65: 355-362.
5. Okudela K, Yazawa T, Ishii J, Woo T, Mitsui H, Bunai T, Sakaeda M, Shimoyamada H, Sato H, Tajiri M, Ogawa N, Masuda M, Sugimura H and Kitamura H. Down-regulation of FXYD3 expression in human lung cancers: its mechanism and potential role in carcinogenesis. Am J Pathol 2009; 175: 2646-2656.
6. Mason DX, Jackson TJ and Lin AW. Molecular signature of oncogenic ras-induced senescence. Oncogene 2004; 23: 9238-9246.
7. Clocchiatti A, Florean C and Brancolini C. Class IIa HDACs: from important roles in differentiation to possible implications in tumourigenesis. J Cell Mol Med 2011; 15: 1833-1846.
8. Tao R, de Zoeten EF, Ozkaynak E, Chen C, Wang L, Porrett PM, Li B, Turka LA, Olson EN, Greene MI, Wells AD and Hancock WW. Deacetylase inhibition promotes the generation and function of regulatory T cells. Nat Med 2007; 13: 1299-1307.
9. Morrison BE and D'Mello SR. Polydactyly in mice lacking HDAC9/HDRP. Exp Biol Med (Maywood) 2008; 233: 980-988.
10. Nishikawa H and Sakaguchi S. Regulatory T cells in tumor immunity. Int J Cancer 2010; 127: 759-767.
11. Milde T, Oehme I, Korshunov A, Kopp-Schneider A, Remke M, Northcott P, Deubzer HE, Lodrini M, Taylor MD, von Deimling A, Pfister S and Witt O. HDAC5 and HDAC9 in medulloblastoma: novel markers for risk stratification and role in tumor cell growth. Clin Cancer Res 2010; 16: 3240-3252.
12. Moreno DA, Scrideli CA, Cortez MA, de Paula Queiroz R, Valera ET, da Silva Silveira V, Yunes JA, Brandalise SR and Tone LG. Differential expression of HDAC3, HDAC7 and HDAC9 is associated with prognosis and survival in childhood acute lymphoblastic leukaemia. Br J Haematol 2010; 150: 665-673.
13. Choi YW, Bae SM, Kim YW, Lee HN, Kim YW, Park TC, Ro DY, Shin JC, Shin SJ, Seo JS and Ahn WS. Gene expression profiles in squamous cell cervical carcinoma using array-based comparative genomic hybridization analysis. Int J Gynecol Cancer 2007; 17: 687-696.
14. Okudela K, Yazawa T, Woo T, Sakaeda M, Ishii J, Mitsui H, Shimoyamada H, Sato H, Tajiri M, Ogawa N, Masuda M, Takahashi T, Sugimura H and Kitamura H. Down-regulation of DUSP6 expression in lung cancer: its mechanism and potential role in carcinogenesis. Am J Pathol 2009; 175: 867-881.
15. Travis WD, Brambilla E, Muller-Hermelink HK and Harris CC. Pathology and Genetics - Tumors of the Lung, Pleura, Thymus and Heart. Lyon: IARC Press, 2004.
16. Cozens AL, Yezzi MJ, Kunzelmann K, Ohrui T, Chin L, Eng K, Finkbeiner WE, Widdicombe JH and Gruenert DC. CFTR expression and chloride secretion in polarized immortal human bronchial epithelial cells. Am J Respir Cell Mol Biol 1994; 10: 38-47.
17. Reinersman JM, Johnson ML, Riely GJ, Chitale DA, Nicastri AD, Soff GA, Schwartz AG, Sima CS, Ayalew G, Lau C, Zakowski MF, Rusch VW, Ladanyi M and Kris MG. Frequency of EGFR and KRAS Mutations in Lung Adenocarcinomas in African Americans. J Thorac Oncol 2011 Jan; 6: 28-31.
18. Schmid K, Oehl N, Wrba F, Pirker R, Pirker C and Filipits M. EGFR/KRAS/BRAF mutations in primary lung adenocarcinomas and corresponding locoregional lymph node metastases. Clin Cancer Res 2009; 15: 4554-4560.
19. Marks JL, Broderick S, Zhou Q, Chitale D, Li AR, Zakowski MF, Kris MG, Rusch VW, Azzoli CG, Seshan VE, Ladanyi M and Pao W. Prognostic and therapeutic implications of EGFR and KRAS mutations in resected lung adenocarcinoma. J Thorac Oncol 2008; 3: 111-116.
20. Lucio-Eterovic AK, Cortez MA, Valera ET, Motta FJ, Queiroz RG, Machado HR, Carlotti CG Jr, Neder L, Scrideli CA and Tone LG. Differential expression of 12 histone deacetylase (HDAC) genes in astrocytomas and normal brain tissue: class II and IV are hypoexpressed in glioblastomas. BMC Cancer 2008; 8: 243.
21. Yuan Z, Peng L, Radhakrishnan R and Seto E. Histone deacetylase 9 (HDAC9) regulates the functions of the ATDC (TRIM29) protein. J Biol Chem 2010; 285: 39329-39338.