Impact of isomalathion on malathion cytotoxicity and genotoxicity in human HepaRG cells

Chemico-Biological Interactions

Volumn 209, Issue 1, 2014, Pages 68-76

  Josse, Rozenn ^a,b   Sharanek, Ahmad ^a,b   Savary, Camille C ^a,b   Guillouzo, Andre ^a,b  

^a INSERM   (France)

^b UNIVERSITÉ DE RENNES 1   (France)

Author keywords

Human hepatocytes; Low doses; Micronucleus assay; Mixture; Pesticides

Indexed keywords

CARBOXYLESTERASE; CASPASE 3; CYTOCHROME P450 1A2; CYTOCHROME P450 2B6; CYTOCHROME P450 3A4; HEME OXYGENASE 1; ISOMALATHION; MALATHION; MANGANESE SUPEROXIDE DISMUTASE; ORGANOPHOSPHATE INSECTICIDE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN HEPARG; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DETOXIFICATION; ENZYME ACTIVITY; ENZYME INHIBITION; GENOTOXICITY; HEALTH HAZARD; HUMAN; HUMAN CELL; LIVER CELL CULTURE; MICRONUCLEUS TEST; OXIDATIVE STRESS; TOXICOKINETICS; WESTERN BLOTTING;

HUMAN HEPATOCYTES; LOW DOSES; MICRONUCLEUS ASSAY; MIXTURE; PESTICIDES;

BLOTTING, WESTERN; CASPASE 3; CELL LINE, TUMOR; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; HEPATOCYTES; HUMANS; MALATHION; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84891687541     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2013.12.002     Document Type: Article

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