Immunoprevalence and immunodominance of HLA-Cw*0801-restricted T cell response targeting the hepatitis B virus envelope transmembrane region

Journal of Virology

Volumn 88, Issue 2, 2014, Pages 1332-1341

  Tan, Anthony T ^a,b   Sodsai, Pimpayao ^b,c   Chia, Adeline ^a,b   Moreau, Eglantine ^b   Chng, Melissa H Y ^b   Tham, Christine Y L ^b   Ho, Zi Zong ^a,b   Banu, Nasirah ^a,b   Hirankarn, Nattiya ^d   Bertoletti, Antonio ^b,e  

^a DUKE NUS MEDICAL SCHOOL   (Singapore)

^b AGENCY FOR SCIENCE   (Singapore)

^c CHULALONGKORN UNIVERSITY   (Thailand)

^d CHULALONGKORN UNIVERSITY   (Thailand)

^e UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; EPITOPE; HEPATITIS B SURFACE ANTIGEN; HLA ANTIGEN CLASS 1;

ADAPTIVE IMMUNITY; ARTICLE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; DISEASE CONTROL; GENOTYPE; HEPATITIS B VIRUS; HLA SYSTEM; HUMAN; MAJOR CLINICAL STUDY; MEMBRANE POTENTIAL; PATHOGENESIS; PREVALENCE; PRIORITY JOURNAL; SOUTHEAST ASIA; T LYMPHOCYTE; VIRUS ENVELOPE; VIRUS REPLICATION;

CD8-POSITIVE T-LYMPHOCYTES; HEPATITIS B; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VIRUS; HLA-A ANTIGENS; HLA-C ANTIGENS; HUMANS; IMMUNITY, CELLULAR; IMMUNODOMINANT EPITOPES; PROTEIN STRUCTURE, TERTIARY; SINGAPORE; THAILAND; VIRAL ENVELOPE PROTEINS;

EID: 84891674603     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.02600-13     Document Type: Article

References (17)

1. Berger CT, Frahm N, Price DA, Mothe B, Ghebremichael M, Hartman KL, Henry LM, Brenchley JM, Ruff LE, Venturi V, Pereyra F, Sidney J, Sette A, Douek DC, Walker BD, Kaufmann DE, Brander C. 2011. High-functional-avidity cytotoxic T lymphocyte responses to HLA-B-restricted Gag-derived epitopes associated with relative HIV control. J. Virol. 85:9334-9345. http://dx.doi.org/10.1128/JVI.00460-11.
2. Bihl F, Frahm N, Di Giammarino L, Sidney J, John M, Yusim K, Woodberry T, Sango K, Hewitt HS, Henry L, Linde CH, Chisholm JV, III, Zaman TM, Pae E, Mallal S, Walker BD, Sette A, Korber BT, Heckerman D, Brander C. 2006. Impact of HLA-B alleles, epitope binding affinity, functional avidity, and viral coinfection on the immunodominance of virus-specific CTL responses. J. Immunol. 176:4094-4101.
3. Blais ME, Dong T, Rowland-Jones S. 2011. HLA-C as a mediator of natural killer and T-cell activation: spectator or key player? Immunology 133:1-7. http://dx.doi.org/10.1111/j.1365-2567.2011.03422.x.
4. Fellay J, Shianna KV, Ge D, Colombo S, Ledergerber B, Weale M, Zhang K, Gumbs C, Castagna A, Cossarizza A, Cozzi-Lepri A, De Luca A, Easterbrook P, Francioli P, Mallal S, Martinez-Picado J, Miro JM, Obel N, Smith JP, Wyniger J, Descombes P, Antonarakis SE, Letvin NL, McMichael AJ, Haynes BF, Telenti A, Goldstein DB. 2007. A wholegenome association study of major determinants for host control of HIV-1. Science 317:944-947. http://dx.doi.org/10.1126/science.1143767.
5. Apps R, Qi Y, Carlson JM, Chen H, Gao X, Thomas R, Yuki Y, Del Prete GQ, Goulder P, Brumme ZL, Brumme CJ, John M, Mallal S, Nelson G, Bosch R, Heckerman D, Stein JL, Soderberg KA, Moody MA, Denny TN, Zeng X, Fang J, Moffett A, Lifson JD, Goedert JJ, Buchbinder S, Kirk GD, Fellay J, McLaren P, Deeks SG, Pereyra F, Walker B, Michael NL, Weintrob A, Wolinsky S, Liao W, Carrington M. 2013. Influence of HLA-C expression level on HIV control. Science 340:87-91. http://dx.doi.org/10.1126/science.1232685.
6. Thomas R, Apps R, Qi Y, Gao X, Male V, O'hUigin C, O'Connor G, Ge D, Fellay J, Martin JN, Margolick J, Goedert JJ, Buchbinder S, Kirk GD, Martin MP, Telenti A, Deeks SG, Walker BD, Goldstein D, McVicar DW, Moffett A, Carrington M. 2009. HLA-C cell surface expression and control of HIV/AIDS correlate with a variant upstream of HLA-C. Nat. Genet. 41:1290-1294. http://dx.doi.org/10.1038/ng.486.
7. Blais ME, Zhang Y, Rostron T, Griffin H, Taylor S, Xu K, Yan H, Wu H, James I, John M, Dong T, Rowland-Jones SL. 2012. High frequency of HIV mutations associated with HLA-C suggests enhanced HLA-C-restricted CTL selective pressure associated with an AIDS-protective polymorphism. J. Immunol. 188:4663-4670. http://dx.doi.org/10.4049/jimmunol.1103472.
8. Cohen GB, Gandhi RT, Davis DM, Mandelboim O, Chen BK, Strominger JL, Baltimore D. 1999. The selective downregulation of class I major histocompatibility complex proteins by HIV-1 protects HIV-infected cells from NK cells. Immunity 10:661-671. http://dx.doi.org/10.1016/S1074-7613(00)80065-5.
9. Chang CX, Tan AT, Or MY, Toh KY, Lim PY, Chia AS, Froesig TM, Nadua KD, Oh HL, Leong HN, Hadrup SR, Gehring AJ, Tan YJ, Bertoletti A, Grotenbreg GM. 2013. Conditional ligands for Asian HLA variants facilitate the definition of CD8+ T-cell responses in acute and chronic viral diseases. Eur. J. Immunol. 43:1109-1120. http://dx.doi.org/10.1002/eji.201243088.
10. Abbott WG, Tsai P, Leung E, Trevarton A, Ofanoa M, Hornell J, Gane EJ, Munn SR, Rodrigo AG. 2010. Associations between HLA class I alleles and escape mutations in the hepatitis B virus core gene in New Zealand-resident Tongans. J. Virol. 84:621-629. http://dx.doi.org/10.1128/JVI.01471-09.
11. + cytotoxic T lymphocytes. J. Clin. Invest. 97:577-584. http://dx.doi.org/10.1172/JCI118450.
12. Desmond CP, Gaudieri S, James IR, Pfafferott K, Chopra A, Lau GK, Audsley J, Day C, Chivers S, Gordon A, Revill PA, Bowden S, Ayres A, Desmond PV, Thompson AJ, Roberts SK, Locarnini SA, Mallal SA, Lewin SR. 2012. Viral adaptation to host immune responses occurs in chronic hepatitis B virus (HBV) infection, and adaptation is greatest in HBV e antigen-negative disease. J. Virol. 86:1181-1192. http://dx.doi.org/10.1128/JVI.05308-11.
13. Tan AT, Loggi E, Boni C, Chia A, Gehring AJ, Sastry KS, Goh V, Fisicaro P, Andreone P, Brander C, Lim SG, Ferrari C, Bihl F, Bertoletti A. 2008. Host ethnicity and virus genotype shape the hepatitis B virusspecific T-cell repertoire. J. Virol. 82:10986-10997. http://dx.doi.org/10.1128/JVI.01124-08.
14. Sandalova E, Laccabue D, Boni C, Watanabe T, Tan A, Zong HZ, Ferrari C, Bertoletti A. 2012. Increased levels of arginase in patients with acute hepatitis B suppress antiviral T cells. Gastroenterology 143:78-87 e73. http://dx.doi.org/10.1053/j.gastro.2012.03.041.
15. Liu MK, Hawkins N, Ritchie AJ, Ganusov VV, Whale V, Brackenridge S, Li H, Pavlicek JW, Cai F, Rose-Abrahams M, Treurnicht F, Hraber P, Riou C, Gray C, Ferrari G, Tanner R, Ping LH, Anderson JA, Swanstrom R, Cohen M, Karim SS, Haynes B, Borrow P, Perelson AS, Shaw GM, Hahn BH, Williamson C, Korber BT, Gao F, Self S, McMichael A, Goonetilleke N. 2013. Vertical T cell immunodominance and epitope entropy determine HIV-1 escape. J. Clin. Invest. 123:380-393. http://dx.doi.org/10.1172/JCI65330.
16. Lepere-Douard C, Trotard M, Le Seyec J, Gripon P. 2009. The first transmembrane domain of the hepatitis B virus large envelope protein is crucial for infectivity. J. Virol. 83:11819-11829. http://dx.doi.org/10.1128/JVI.01026-09.
17. Siegler VD, Bruss V. 2013. Role of transmembrane domains of hepatitis B virus small surface proteins in subviral-particle biogenesis. J. Virol. 87:1491-1496. http://dx.doi.org/10.1128/JVI.02500-12.