High frequency of HIV mutations associated with HLA-C suggests enhanced HLA-C - Restricted CTL selective pressure associated with an AIDS-protective polymorphism

Journal of Immunology

Volumn 188, Issue 9, 2012, Pages 4663-4670

  Blais, Marie Eve ^a   Zhang, Yonghong ^a,b   Rostron, Tim ^a   Griffin, Harry ^a   Taylor, Stephen ^a   Xu, Keyi ^c   Yan, Huiping ^b   Wu, Hao ^b   James, Ian ^d   John, Mina ^d   Dong, Tao ^a,b   Rowland Jones, Sarah L ^a  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^b CAPITAL MEDICAL UNIVERSITY   (China)

^c CAPITAL MEDICAL UNIVERSITY   (China)

^d MURDOCH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; HLA C ANTIGEN; VIRUS DNA;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANTIGEN EXPRESSION; ARTICLE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CHINA; CLADISTICS; COHORT ANALYSIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXIC T LYMPHOCYTE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC CORRELATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; IN VIVO STUDY; INFECTION CONTROL; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; VIRUS MUTATION; VIRUS STRAIN;

3' UNTRANSLATED REGIONS; ACQUIRED IMMUNODEFICIENCY SYNDROME; ALLELES; ASIAN CONTINENTAL ANCESTRY GROUP; CD8-POSITIVE T-LYMPHOCYTES; CHINA; DNA, VIRAL; FEMALE; GENE EXPRESSION REGULATION; HIV-1; HLA-C ANTIGENS; HUMANS; INTERFERON-GAMMA; MALE; MUTATION; POLYMORPHISM, GENETIC; PROVIRUSES; RETROSPECTIVE STUDIES;

EID: 84860337141     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1103472     Document Type: Article

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