Trends in drug-delivery-system microfabrication and a new scalable technology using x-ray synchrotron irradiation

2013 Transducers and Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013

Volumn , Issue , 2013, Pages 1603-1608

  Cho, D I ^a,b   Yoo, H J ^a,b   Lee, S ^a,b   Hong, S J ^a,b   Seo, J M ^b   Kim, T Y ^c   Kim, S J ^b  

^a Department of Aerospace Engineering   (South Korea)

^b Department of Electrical Engineering and Computer Science ^*  (South Korea)

^c Seoul National University   (South Korea)

Author keywords

bacterial migration; biodegradable polymers; Drug delivery systems (DDS); microfabrication; nanofabrication; targeted drug delivery; x ray synchrotron irradiation

Indexed keywords

BACTERIAL MIGRATION; DRUG DELIVERY SYSTEM; LASER MICRO-MACHINING; MICRO-FABRICATION TECHNIQUES; POLYMERIC MICRODEVICES; REPLICATION TECHNIQUES; TARGETED DRUG DELIVERY; X-RAY SYNCHROTRON;

ACTUATORS; BIOCHEMISTRY; BIODEGRADABLE POLYMERS; DRUG DELIVERY; IRRADIATION; MICROANALYSIS; MICROFABRICATION; MICROSYSTEMS; NANOTECHNOLOGY; SOLID-STATE SENSORS;

X RAYS;

EID: 84891667777     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/Transducers.2013.6627090     Document Type: Conference Paper

References (32)

1. C. A. Lipinski, F. Lombardo, B. W. Dominy, and P. J. Feeney, "Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings," Adv. Drug Deliv. Rev., vol. 64, pp. 4-17, 2012.
2. N. Van Bruggen, H. Thibodeaux, J. T. Palmer, W. P. Lee, L. Fu, B. Cairns, et al., "VEGF antagonism reduces edema formation and tissue damage after ischemia/reperfusion injury in the mouse brain," J. Clin. Invest., vol. 104, pp. 1613-1620, 1999.
3. T. M. Allen and P. R. Cullis, "Drug delivery systems: entering the mainstream," Science, vol. 303, pp. 1818-1822, 2004.
4. R. R. Dmochowski and D. R. Staskin, "Advances in drug delivery: improved bioavailability and drug effect," Curr. Urol. Rep., vol. 3, pp. 439-444, 2002.
5. Y. Zhang, H. F. Chan, and K. W. Leong, "Advanced materials and processing for drug delivery: The past and the future," Adv. Drug Deliv. Rev., vol. 65, pp. 104-120, 2013.
6. Y. Lu and S. Chen, "Micro and nano-fabrication of biodegradable polymers for drug delivery," Adv. Drug Deliv. Rev., vol. 56, pp. 1621-1633, 2004.
7. K. S. Soppimath, T. M. Aminabhavi, A. R. Kulkarni, and W. E. Rudzinski, "Biodegradable polymeric nanoparticles as drug delivery devices," J. Control. Release, vol. 70, pp. 1-20, 2001.
8. Sharma and R. M. Straubinger, "Novel taxol formulations: preparation and characterization of taxol-containing liposomes," Pharmaceutical research, vol. 11, pp. 889-896, 1994.
9. S. Tan, X. Li, Y. Guo, and Z. Zhang, "Lipid-enveloped hybrid nanoparticles for drug delivery," Nanoscale, vol. 5, pp. 860-872, 2013.
10. R. Jain, N. H. Shah, A. W. Malick, and C. T. Rhodes, "Controlled drug delivery by biodegradable poly (ester) devices: different preparative approaches," Drug Dev. Ind. Pharm., vol. 24, pp. 703-727, 1998.
11. R. Langer and J. Folkman, "Polymers for the sustained release of proteins and other macromolecules," Nature, vol. 263, pp. 797-800, 1976.
12. D. W. Hutmacher, "Scaffolds in tissue engineering bone and cartilage," Biomaterials, vol. 21, pp. 2529-2543, 2000.
13. J.-J. Min, V. H. Nguyen, H.-J. Kim, Y. Hong, and H. E. Choy, "Quantitative bioluminescence imaging of tumor-targeting bacteria in living animals," Nature protocols, vol. 3, pp. 629-636, 2008.
14. S. J. Park, H. Bae, J. Kim, B. Lim, J. Park and S. Park, "Motility enhancement of bacteria actuated microstructures using selective bacteria adhesion," Lab Chip, vol. 10, pp. 1706-1711, 2010.
15. H. J. Yoo, S. Lee, J. H. Ahn, S. J. Hong, M. Lee, J. M. Seo, T. Y. Kim, S. J. Kim and D. I. Cho, "Laminated, cubic, biodegradable polymer structures for bacteria-based, robotic drug delivery," in Global Congress on Nano-Medicine: Nano-Bio-Info Convergence, 2012, pp. 85483S-85483S-7.
16. R. Crafer and P. J. Oakley, Laser processing in manufacturing: Springer, pp. 1-20, 1992.
17. Aguilar, Y. Lu, S. Mao, and S. Chen, "Direct micro-patterning of biodegradable polymers using ultraviolet and femtosecond lasers," Biomaterials, vol. 26, pp. 7642-7649, 2005.
18. Zein, D. W. Hutmacher, K. C. Tan, and S. H. Teoh, "Fused deposition modeling of novel scaffold architectures for tissue engineering applications," Biomaterials, vol. 23, pp. 1169-1185, 2002.
19. M. Wu, S. W. Borland, R. A. Giordano, L. G. Cima, E. M. Sachs, and M. J. Cima, "Solid free-form fabrication of drug delivery devices," J. Control. Release, vol. 40, pp. 77-87, 1996.
20. M. N. Cooke, J. P. Fisher, D. Dean, C. Rimnac, and A. G. Mikos, "Use of stereolithography to manufacture critical-sized 3D biodegradable scaffolds for bone ingrowth," J. Biomed. Mater. Res. Part B Appl. Biomater., vol. 64, pp. 65-69, 2002.
21. L. C. Glangchai, M. Caldorera-Moore, L. Shi, and K. Roy, "Nanoimprint lithography based fabrication of shape-specific, enzymatically-triggered smart nanoparticles," J. Control. Release, vol. 125, pp. 263-272, 2008.
22. S. Xiong, X. Zhao, B. C. Heng, K. W. Ng, and J. S. C. Loo, "Cellular uptake of Poly?(D, L?lactide?co?glycolide)(PLGA) nanoparticles synthesized through solvent emulsion evaporation and nanoprecipitation method," Biotechnology Journal, vol. 6, pp. 501-508, 2011.
23. Y. Liu and X. Deng, "Influences of preparation conditions on particle size and DNA-loading efficiency for poly (dl-lactic acid-polyethylene glycol) microspheres entrapping free DNA," J. Control. Release, vol. 83, pp. 147-155, 2002.
24. D. Rosca, F. Watari, and M. Uo, "Microparticle formation and its mechanism in single and double emulsion solvent evaporation," J. Control. Release, Vol. 99, pp. 271-280, 2004.
25. J. Halliday, S. E. Moulton, G. G. Wallace, and M. J. Cook, "Novel methods of antiepileptic drug delivery-polymer-based implants," Adv. Drug Deliv. Rev., vol 64, pp. 953-964, 2012
26. W. J. Duncanson, T. Lin, A. R. Abate, S. Seiffert, R. K. Shah, and D. A. Weitz, "Microfluidic synthesis of advanced microparticles for encapsulation and controlled release," Lab Chip, vol. 12, pp. 2135-2145, 2012.
27. L. L. A. Adams, T. E. Kodger, S. H. Kim, H. C. Shum, T. Franke, and D. A. Weitz, "Single step emulsification for the generation of multi-component double emulsions," Soft Matter, vol. 8, pp. 10719-10724, 2012.
28. Spiller, et al., "Application of synchrotron radiation to x?ray lithography," J. Appl. Phys., vol. 47, pp. 5450-5459, 1976.
29. Becker, W. Ehrfeld, P. Hagmann, A. Maner, and D. Münchmeyer, "Fabrication of microstructures with high aspect ratios and great structural heights by synchrotron radiation lithography, galvanoforming, and plastic moulding (LIGA process)," Microelectron. Eng., vol. 4, pp. 35-56, 1986.
30. http://pal.postech.ac.kr
31. Schmalz, O., Hess, M. and Kosfeld, R., "Structural changes in poly(methyl methacrylate) during deep-etch X-ray synchrotron radiation lithography. Part II: Radiation effects on PMMA," Angew. Makromol. Chem., vol. 239, pp. 79-91, 1996.
32. Cam, D., Hyon, S. H., and Ikada, Y., "Degradation of high molecular weight poly (L-lactide) in alkaline medium," Biomaterials, vol. 16, pp. 833-843, 1995.