A case-control study on the effect of metabolic gene polymorphisms, nutrition, and their interaction on the risk of non-alcoholic fatty liver disease

Genes and Nutrition

Volumn 9, Issue 2, 2014, Pages

  Miele, Luca ^a,b   Dall'Armi, Valentina ^c   Cefalo, Consuelo ^a   Nedovic, Bojan ^a   Arzani, Dario ^a   Amore, Rosarita ^a   Rapaccini, Gianlodovico ^a,b   Gasbarrini, Antonio ^a   Ricciardi, Walter ^a   Grieco, Antonio ^a   Boccia, Stefania ^a,c  

^a CATHOLIC UNIVERSITY   (Italy)

^b Sect Int Med and Gastroenterology   (Italy)

^c IRCCS SAN RAFFAELE PISANA   (Italy)

Author keywords

Gene environment interaction; Metabolic genes; Non alcoholic fatty liver disease; Nutrition; Polymorphism

Indexed keywords

CYTOCHROME; GLUTATHIONE TRANSFERASE; SULFOTRANSFERASE;

1A1 GENE; ADULT; ALCOHOL CONSUMPTION; ARTICLE; CASE CONTROL STUDY; CONTROLLED STUDY; CYP2E1 GENE; DISEASE ASSOCIATION; DNA EXTRACTION; DRINKING BEHAVIOR; FAT INTAKE; FEMALE; FOOD INTAKE; GENE; GENE INTERACTION; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; GSTM1 GENE; GSTT1 GENE; HUMAN; LIFESTYLE; MAJOR CLINICAL STUDY; MALE; NONALCOHOLIC FATTY LIVER; NUTRITION; OXIDATIVE STRESS; PHYSICAL ACTIVITY; RISK ASSESSMENT; RISK FACTOR; SULT1A1 GENE;

EID: 84891643660     PISSN: 15558932     EISSN: 18653499     Source Type: Journal    
DOI: 10.1007/s12263-013-0383-1     Document Type: Article

References (43)

1. Abdelmalek MF, Suzuki A, Guy C, Unalp-Arida A, Colvin R, Johnson RJ, Diehl AM, Nonalcoholic Steatohepatitis Clinical Research Network (2010) Increased fructose consumption is associated with fibrosis severity in patients with nonalcoholic fatty liver disease. Hepatology 51:1961-1971
2. Abid A, Taha O, Nseir W, Farah R, Grosovski M, Assy N (2009) Soft drink consumption is associated with fatty liver disease independent of metabolic syndrome. J Hepatol 51:918-924
3. Adams LA, Lymp JF, St Sauver J, Sanderson SO, Lindor KD, Feldstein A, Angulo P (2005) The natural history of nonalcoholic fatty liver disease: a population-based cohort study. Gastroenterology 129:113-121 (Pubitemid 41002048)
4. Arand M, Muhlbauer R, Hengstler J, Jager E, Fuchs J, Winkler L, Oesch F (1996) A multiplex polymerase chain reaction protocol for the simultaneous analysis of the glutathione S-transferase GSTM1 and GSTT1 polymorphisms. Anal Biochem 236:184-186 (Pubitemid 26100747)
5. Bell LN, Molleston JP, Morton MJ, Klipsch A, Saxena R, Vuppalanchi R, Chalasani N (2011) Hepatic lipid peroxidation and cytochrome P-450 2E1 in pediatric nonalcoholic fatty liver disease and its subtypes. J Clin Gastroenterol 45:800-807
6. Bolt HM, Thier R (2006) Relevance of the deletion polymorphisms of the glutathione S-transferases GSTT1 and GSTM1 in pharmacology and toxicology. Curr Drug Metab 7:613-628 (Pubitemid 44226589)
7. Chalasani N, Younossi Z, Lavine JE, Diehl AM, Brunt EM, Cusi K, Charlton M, Sanyal AJ (2012) The diagnosis and management of non-alcoholic fatty liver disease: practice guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association. Am J Gastroenterol 107:811-826
8. Church TS, Kuk JL, Ross R, Priest EL, Biltoft E, Blair SN (2006) Association of cardiorespiratory fitness, body mass index, and waist circumference to nonalcoholic fatty liver disease. Gastroenterology 130:2023-2030 (Pubitemid 43816951)
9. Cordell HJ, Clayton DG (2005) Genetic association studies. Lancet 366:1121-1131 (Pubitemid 41338767)
10. Coughtrie MW, Gilissen RA, Shek B, Strange RC, Fryer AA, Jones PW, Bamber DE (1999) Phenol sulphotransferase SULT1A1 polymorphism: molecular diagnosis and allele frequencies in Caucasian and African populations. Biochem J 337:45-49 (Pubitemid 29039081)
11. Daly AK, Ballestri S, Carulli L, Loria P, Day CP (2011) Genetic determinants of susceptibility and severity in nonalcoholic fatty liver disease. Expert Rev Gastroenterol Hepatol 5:253-263
12. De Feo E, Cefalo C, Arzani D, Amore R, Landolfi R, Grieco A, Ricciardi W, Miele L, Boccia S (2012) A case-control study on the effects of the apolipoprotein E genotypes in nonalcoholic fatty liver disease. Mol Biol Rep 39:7381-7388
13. Djousse L, Himali JJ, Beiser A, Kelly-Hayes M, Wolf PA (2009) Apolipoprotein e, alcohol consumption, and risk of ischemic stroke: the Framingham Heart Study revisited. J Stroke Cerebrovasc Dis 18:384-388
14. Doney AS, Lee S, Leese GP, Morris AD, Palmer CN (2005) Increased cardiovascular morbidity and mortality in type 2 diabetes is associated with the glutathione S transferase theta-null genotype: a Go-DARTS study. Circulation 111:2927-2934 (Pubitemid 40814185)
15. Dunn W, Xu R, Schwimmer JB (2008) Modest wine drinking and decreased prevalence of suspected nonalcoholic fatty liver disease. Hepatology 47:1947-1954 (Pubitemid 351945562)
16. Fisher CD, Lickteig AJ, Augustine LM, Ranger-Moore J, Jackson JP, Ferguson SS, Cherrington NJ (2009) Hepatic cytochrome P450 enzyme alterations in humans with progressive stages of nonalcoholic fatty liver disease. Drug Metab Dispos 37:2087-2094
17. Hardwick RN, Ferreira DW, More VR, Lake AD, Lu Z, Manautou JE, Slitt AL, Cherrington NJ (2013) Altered UDP-glucuronosyltransferase and sulfotransferase expression and function during progressive stages of human nonalcoholic fatty liver disease. Drug Metab Dispos 41:554-561
18. Hashemi M, Eskandari-Nasab E, Fazaeli A, Bahari A, Hashemzehi NA, Shafieipour S, Taheri M, Moazeni-Roodi A, Zakeri Z, Bakhshipour A, Ghavami S (2012) Association of genetic polymorphisms of glutathione-S-transferase genes (GSTT1, GSTM1, and GSTP1) and susceptibility to nonalcoholic fatty liver disease in Zahedan, Southeast Iran. DNA Cell Biol 31:672-677
19. Hijona E, Hijona L, Arenas JI, Bujanda L (2010) Inflammatory mediators of hepatic steatosis. Mediators Inflamm 2010:837419
20. Hori M, Oniki K, Nakagawa T, Takata K, Mihara S, Marubayashi T, Nakagawa K (2009) Association between combinations of glutathione-S-transferase M1, T1 and P1 genotypes and nonalcoholic fatty liver disease. Liver Int 29:164-168
21. Huang YS, Su WJ, Huang YH, Chen CY, Chang FY, Lin HC, Lee SD (2007) Genetic polymorphisms of manganese superoxide dismutase, NAD(P)H: quinone oxidoreductase, glutathione S-transferase M1 and T1, and the susceptibility to drug-induced liver injury. J Hepatol 47:128-134
22. Khan AJ, Ruwali M, Choudhuri G, Mathur N, Husain Q, Parmar D (2009) Polymorphism in cytochrome P450 2E1 and interaction with other genetic risk factors and susceptibility to alcoholic liver cirrhosis. Mutat Res 664(1-2):55-63
23. Lim JS, Mietus-Snyder M, Valente A, Schwarz JM, Lustig RH (2010) The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome. Nat Rev Gastroenterol Hepatol 7:251-264
24. Loomba R, Sanyal AJ (2013) The global NAFLD epidemic. Nat Rev Gastroenterol Hepatol. doi:10.1038/nrgastro.2013.171
25. Loria P, Adinolfi LE, Bellentani S, Bugianesi E, Grieco A, Fargion S, Gasbarrini A, Loguercio C, Lonardo A, Marchesini G, Marra F, Persico M, Prati D, Baroni GS (2010) Practice guidelines for the diagnosis and management of nonalcoholic fatty liver disease. A decalogue from the Italian Association for the Study of the Liver (AISF) Expert Committee. Dig Liver Dis 42:272-282
26. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC (1985) Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28:412-419 (Pubitemid 15018832)
27. Miele L, Forgione A, Hernandez AP, Gabrieli ML, Vero V, Di Rocco P, Greco AV, Gasbarrini G, Gasbarrini A, Grieco A (2005) The natural history and risk factors for progression of non-alcoholic fatty liver disease and steatohepatitis. Eur Rev Med Pharmacol Sci 9:273-277 (Pubitemid 41387391)
28. Miele L, Valenza V, La Torre G, Montalto M, Cammarota G, Ricci R, Masciana R, Forgione A, Gabrieli ML, Perotti G, Vecchio FM, Rapaccini G, Gasbarrini G, Day CP, Grieco A (2009) Increased intestinal permeability and tight junction alterations in nonalcoholic fatty liver disease. Hepatology 49:1877-1887
29. Oddy WH, Herbison CE, Jacoby P, Ambrosini GL, O'Sullivan TA, Ayonrinde OT, Olynyk JK, Black LJ, Beilin LJ, Mori TA, Hands BP, Adams LA (2013) The Western dietary pattern is prospectively associated with nonalcoholic fatty liver disease in adolescence. Am J Gastroenterol 108:778-785
30. Oniki K, Ueda K, Hori M, Mihara S, Marubayashi T, Nakagawa K (2007) Glutathione-S-transferase (GST)M1 null genotype and combined GSTM1 and GSTT1 null genotypes as a risk factor for alcoholic mild liver dysfunction. Clin Pharmacol Ther 81:634-635 (Pubitemid 46625110)
31. Ruwali M, Khan AJ, Shah PP, Singh AP, Pant MC, Parmar D (2009) Cytochrome P450 2E1 and head and neck cancer: interaction with genetic and environmental risk factors. Environ Mol Mutagen 5(6):473-482
32. Sanyal AJ (2002) AGA technical review on nonalcoholic fatty liver disease. Gastroenterology 123:1705-1725
33. Shi L, Liu ZW, Li Y, Gong C, Zhang H, Song LJ, Huang CY, Li M (2012) The prevalence of nonalcoholic fatty liver disease and its association with lifestyle/dietary habits among university faculty and staff in Chengdu. Biomed Environ Sci 25:383-391
34. Solga S, Alkhuraishe AR, Clark JM, Torbenson M, Greenwald A, Diehl AM, Magnuson T (2004) Dietary composition and nonalcoholic fatty liver disease. Dig Dis Sci 49:1578-1583 (Pubitemid 39335538)
35. Sookoian S, Pirola CJ (2011) Meta-analysis of the influence of I148M variant of patatin-like phospholipase domain containing 3 gene (PNPLA3) on the susceptibility and histological severity of nonalcoholic fatty liver disease. Hepatology 53(6):1883-1894
36. Sumida Y, Niki E, Naito Y, Yoshikawa T (2013) Involvement of free radicals and oxidative stress in NAFLD/NASH. Free Radic Res 47:869-880
37. Tappy L, Le KA (2012) Does fructose consumption contribute to nonalcoholic fatty liver disease? Clin Res Hepatol Gastroenterol 36:554-560
38. Targher G, Day CP, Bonora E (2010) Risk of cardiovascular disease in patients with nonalcoholic fatty liver disease. N Engl J Med 363:1341-1350
39. Tilg H, Moschen AR (2010) Evolution of inflammation in nonalcoholic fatty liver disease: the multiple parallel hits hypothesis. Hepatology 52:1836-1846
40. Ueda K, Ishitsu T, Seo T, Ueda N, Murata T, Hori M, Nakagawa K (2007) Glutathione S-transferase M1 null genotype as a risk factor for carbamazepine-induced mild hepatotoxicity. Pharmacogenomics 8:435-442 (Pubitemid 46746351)
41. Varela NM, Quiñones LA, Orellana M, Poniachik J, Csendes A, Smok G, Rodrigo R, Cáceres DD, Videla LA (2008) Study of cytochrome P450 2E1 and its allele variants in liver injury of nondiabetic, nonalcoholic steatohepatitis obese women. Biol Res 41:81-92
42. Zelber-Sagi S, Nitzan-Kaluski D, Goldsmith R, Webb M, Zvibel I, Goldiner I, Blendis L, Halpern Z, Oren R (2008) Role of leisuretime physical activity in nonalcoholic fatty liver disease: a population-based study. Hepatology 48:1791-1798
43. Zelber-Sagi S, Ratziu V, Oren R (2011) Nutrition and physical activity in NAFLD: an overview of the epidemiological evidence. World J Gastroenterol 17:3377-3389