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Volumn 387, Issue 1, 2014, Pages 23-32

Escitalopram block of hERG potassium channels

Author keywords

Channel trafficking; Citalopram; Escitalopram; hERG

Indexed keywords

CITALOPRAM; ESCITALOPRAM; POTASSIUM CHANNEL HERG;

EID: 84891623820     PISSN: 00281298     EISSN: 14321912     Source Type: Journal    
DOI: 10.1007/s00210-013-0911-y     Document Type: Article
Times cited : (37)

References (33)
  • 1
    • 47549084134 scopus 로고    scopus 로고
    • Corrected QT interval prolongation after an overdose of escitalopram, morphine, oxycodone, zopiclone and benzodiazepines
    • 18612505 10.1016/S0828-282X(08)70643-3
    • Baranchuk A, Simpson CS, Methot M, Gibson K, Strum D (2008) Corrected QT interval prolongation after an overdose of escitalopram, morphine, oxycodone, zopiclone and benzodiazepines. Can J Cardiol 24:e38-e40
    • (2008) Can J Cardiol , vol.24
    • Baranchuk, A.1    Simpson, C.S.2    Methot, M.3    Gibson, K.4    Strum, D.5
  • 2
    • 2342605426 scopus 로고    scopus 로고
    • Blockers of the Kv1.5 channel for the treatment of atrial arrhythmias
    • 1:CAS:528:DC%2BD3sXnslyqur0%3D 15326917 10.2174/1568016033477441
    • Brendel J, Peukert S (2003) Blockers of the Kv1.5 channel for the treatment of atrial arrhythmias. Curr Med Chem Cardiovasc Hematol Agents 1:273-287
    • (2003) Curr Med Chem Cardiovasc Hematol Agents , vol.1 , pp. 273-287
    • Brendel, J.1    Peukert, S.2
  • 3
    • 0030075361 scopus 로고    scopus 로고
    • Combined potassium and calcium channel blocking activities as a basis for antiarrhythmic efficacy with low proarrhythmic risk: Experimental profile of BRL-32872
    • 1:CAS:528:DyaK28XhtFakt78%3D 8632331
    • Bril A, Gout B, Bonhomme M, Landais L, Faivre JF, Linee P, Poyser RH, Ruffolo RR Jr (1996) Combined potassium and calcium channel blocking activities as a basis for antiarrhythmic efficacy with low proarrhythmic risk: experimental profile of BRL-32872. J Pharmacol Exp Ther 276:637-646
    • (1996) J Pharmacol Exp Ther , vol.276 , pp. 637-646
    • Bril, A.1    Gout, B.2    Bonhomme, M.3    Landais, L.4    Faivre, J.F.5    Linee, P.6    Poyser, R.H.7    Ruffolo, Jr.R.R.8
  • 4
    • 0034973504 scopus 로고    scopus 로고
    • QTc interval prolongation associated with citalopram overdose: A case report and literature review
    • 1:STN:280:DC%2BD3MzhvFOhtw%3D%3D 11391127 10.1097/00002826-200105000- 00007
    • Catalano G, Catalano MC, Epstein MA, Tsambiras PE (2001) QTc interval prolongation associated with citalopram overdose: a case report and literature review. Clin Neuropharmacol 24:158-162
    • (2001) Clin Neuropharmacol , vol.24 , pp. 158-162
    • Catalano, G.1    Catalano, M.C.2    Epstein, M.A.3    Tsambiras, P.E.4
  • 6
    • 80053213512 scopus 로고    scopus 로고
    • Antidepressant-induced ubiquitination and degradation of the cardiac potassium channel hERG
    • 1:CAS:528:DC%2BC3MXht1ajtbrN 21832094 10.1074/jbc.M111.254367
    • Dennis AT, Nassal D, Deschenes I, Thomas D, Ficker E (2011) Antidepressant-induced ubiquitination and degradation of the cardiac potassium channel hERG. J Biol Chem 286:34413-34425
    • (2011) J Biol Chem , vol.286 , pp. 34413-34425
    • Dennis, A.T.1    Nassal, D.2    Deschenes, I.3    Thomas, D.4    Ficker, E.5
  • 7
    • 0042668403 scopus 로고    scopus 로고
    • Cardiotoxicity and late onset seizures with citalopram overdose
    • 12902002 10.1016/S0736-4679(03)00164-1
    • Engebretsen KM, Harris CR, Wood JE (2003) Cardiotoxicity and late onset seizures with citalopram overdose. J Emerg Med 25:163-166
    • (2003) J Emerg Med , vol.25 , pp. 163-166
    • Engebretsen, K.M.1    Harris, C.R.2    Wood, J.E.3
  • 9
    • 65649088361 scopus 로고    scopus 로고
    • State-dependent block of HERG potassium channels by R-roscovitine: Implications for cancer therapy
    • 1:CAS:528:DC%2BD1MXkvVyhs7o%3D 19244476 10.1152/ajpcell.00633.2008
    • Ganapathi SB, Kester M, Elmslie KS (2009) State-dependent block of HERG potassium channels by R-roscovitine: implications for cancer therapy. Am J Physiol Cell Physiol 296:C701-C710
    • (2009) Am J Physiol Cell Physiol , vol.296
    • Ganapathi, S.B.1    Kester, M.2    Elmslie, K.S.3
  • 10
    • 77956223300 scopus 로고    scopus 로고
    • Escitalopram: A review of its use in the management of major depressive disorder in adults
    • 1:CAS:528:DC%2BC3cXhtlShurjE 20806989 10.2165/11204760-000000000-00000
    • Garnock-Jones KP, McCormack PL (2010) Escitalopram: a review of its use in the management of major depressive disorder in adults. CNS Drugs 24:769-796
    • (2010) CNS Drugs , vol.24 , pp. 769-796
    • Garnock-Jones, K.P.1    McCormack, P.L.2
  • 11
    • 0020416931 scopus 로고
    • Citalopram - Pharmacological profile of a specific serotonin uptake inhibitor with antidepressant activity
    • 1:CAS:528:DyaL3sXkvA%3D%3D 6128769 10.1016/S0278-5846(82)80179-6
    • Hyttel J (1982) Citalopram - pharmacological profile of a specific serotonin uptake inhibitor with antidepressant activity. Prog Neuropsychopharmacol Biol Psychiatry 6:277-295
    • (1982) Prog Neuropsychopharmacol Biol Psychiatry , vol.6 , pp. 277-295
    • Hyttel, J.1
  • 12
    • 0034710954 scopus 로고    scopus 로고
    • Channel structure and drug-induced cardiac arrhythmias
    • 1:CAS:528:DC%2BD3cXnvVShu7s%3D 34333 11050193 10.1073/pnas.97.22.11683
    • Kass RS, Cabo C (2000) Channel structure and drug-induced cardiac arrhythmias. Proc Natl Acad Sci U S A 97:11683-11684
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 11683-11684
    • Kass, R.S.1    Cabo, C.2
  • 13
    • 0034531061 scopus 로고    scopus 로고
    • Citalopram therapy for depression: A review of 10 years of European experience and data from US clinical trials
    • 1:CAS:528:DC%2BD3MXhtVChtrw%3D 11206593 10.4088/JCP.v61n1202
    • Keller MB (2000) Citalopram therapy for depression: a review of 10 years of European experience and data from U.S. clinical trials. J Clin Psychiatry 61:896-908
    • (2000) J Clin Psychiatry , vol.61 , pp. 896-908
    • Keller, M.B.1
  • 15
    • 77952119359 scopus 로고    scopus 로고
    • Open channel block of Kv1.5 currents by citalopram
    • 1:CAS:528:DC%2BC3cXkt1Wkt7s%3D 20228830 10.1038/aps.2010.14
    • Lee HM, Hahn SJ, Choi BH (2010) Open channel block of Kv1.5 currents by citalopram. Acta Pharmacol Sin 31:429-435
    • (2010) Acta Pharmacol Sin , vol.31 , pp. 429-435
    • Lee, H.M.1    Hahn, S.J.2    Choi, B.H.3
  • 16
    • 0021591318 scopus 로고
    • Distribution of citalopram in the blood serum and in the central nervous system of rats after single and multiple dosage
    • 1:CAS:528:DyaL2MXktVSitr4%3D 6598490
    • Melzacka M, Rurak A, Adamus A, Daniel W (1984) Distribution of citalopram in the blood serum and in the central nervous system of rats after single and multiple dosage. Pol J Pharmacol Pharm 36:675-682
    • (1984) Pol J Pharmacol Pharm , vol.36 , pp. 675-682
    • Melzacka, M.1    Rurak, A.2    Adamus, A.3    Daniel, W.4
  • 17
    • 0038497465 scopus 로고    scopus 로고
    • Blockade of HERG potassium currents by fluvoxamine: Incomplete attenuation by S6 mutations at F656 or Y652
    • 1:CAS:528:DC%2BD3sXlvVCjurY%3D 12839862 10.1038/sj.bjp.0705335
    • Milnes JT, Crociani O, Arcangeli A, Hancox JC, Witchel HJ (2003) Blockade of HERG potassium currents by fluvoxamine: incomplete attenuation by S6 mutations at F656 or Y652. Br J Pharmacol 139:887-898
    • (2003) Br J Pharmacol , vol.139 , pp. 887-898
    • Milnes, J.T.1    Crociani, O.2    Arcangeli, A.3    Hancox, J.C.4    Witchel, H.J.5
  • 19
    • 0034000672 scopus 로고    scopus 로고
    • Cardiac electrophysiological effects of citalopram in guinea pig papillary muscle comparison with clomipramine
    • 1:CAS:528:DC%2BD3cXivVGms7w%3D 10793264 10.1016/S0306-3623(99)00048-8
    • Pacher P, Bagi Z, Lako-Futo Z, Ungvari Z, Nanasi PP, Kecskemeti V (2000) Cardiac electrophysiological effects of citalopram in guinea pig papillary muscle comparison with clomipramine. Gen Pharmacol 34:17-23
    • (2000) Gen Pharmacol , vol.34 , pp. 17-23
    • Pacher, P.1    Bagi, Z.2    Lako-Futo, Z.3    Ungvari, Z.4    Nanasi, P.P.5    Kecskemeti, V.6
  • 20
    • 3242884869 scopus 로고    scopus 로고
    • Cardiovascular side effects of new antidepressants and antipsychotics: New drugs, old concerns?
    • 1:CAS:528:DC%2BD2cXlslWjsbs%3D 2493295 15320756 10.2174/1381612043383872
    • Pacher P, Kecskemeti V (2004) Cardiovascular side effects of new antidepressants and antipsychotics: new drugs, old concerns? Curr Pharm Des 10:2463-2475
    • (2004) Curr Pharm des , vol.10 , pp. 2463-2475
    • Pacher, P.1    Kecskemeti, V.2
  • 21
    • 0034083113 scopus 로고    scopus 로고
    • Citalopram in the treatment of depression
    • 1:CAS:528:DC%2BD3cXksF2qtb4%3D 10860138 10.1345/aph.19137
    • Parker NG, Brown CS (2000) Citalopram in the treatment of depression. Ann Pharmacother 34:761-771
    • (2000) Ann Pharmacother , vol.34 , pp. 761-771
    • Parker, N.G.1    Brown, C.S.2
  • 22
    • 0035987783 scopus 로고    scopus 로고
    • Inhibition of the current of heterologously expressed HERG potassium channels by flecainide and comparison with quinidine, propafenone and lignocaine
    • 1:CAS:528:DC%2BD38XlsFKlt74%3D 12086981 10.1038/sj.bjp.0704784
    • Paul AA, Witchel HJ, Hancox JC (2002) Inhibition of the current of heterologously expressed HERG potassium channels by flecainide and comparison with quinidine, propafenone and lignocaine. Br J Pharmacol 136:717-729
    • (2002) Br J Pharmacol , vol.136 , pp. 717-729
    • Paul, A.A.1    Witchel, H.J.2    Hancox, J.C.3
  • 25
    • 33747033403 scopus 로고    scopus 로고
    • The pharmacology of citalopram enantiomers: The antagonism by R-citalopram on the effect of S-citalopram
    • 1:CAS:528:DC%2BD28Xpt1egsrk%3D 16918708 10.1111/j.1742-7843.2006.pto-295. x
    • Sanchez C (2006) The pharmacology of citalopram enantiomers: the antagonism by R-citalopram on the effect of S-citalopram. Basic Clin Pharmacol Toxicol 99:91-95
    • (2006) Basic Clin Pharmacol Toxicol , vol.99 , pp. 91-95
    • Sanchez, C.1
  • 26
    • 0036151533 scopus 로고    scopus 로고
    • The antidepressant drug fluoxetine is an inhibitor of human ether-A-Go-Go-Related gene (HERG) potassium channels
    • 1:CAS:528:DC%2BD38Xos1yktA%3D%3D 11805215 10.1124/jpet.300.2.543
    • Thomas D, Gut B, Wendt-Nordahl G, Kiehn J (2002) The antidepressant drug fluoxetine is an inhibitor of human ether-a-go-go-related gene (HERG) potassium channels. J Pharmacol Exp Ther 300:543-548
    • (2002) J Pharmacol Exp Ther , vol.300 , pp. 543-548
    • Thomas, D.1    Gut, B.2    Wendt-Nordahl, G.3    Kiehn, J.4
  • 27
    • 84857367918 scopus 로고    scopus 로고
    • Low-dose escitalopram for 2 days associated with corrected QT interval prolongation in a middle-aged woman: A case report and literature review
    • Tseng PT, Lee Y, Lin YE, Lin PY (2012) Low-dose escitalopram for 2 days associated with corrected QT interval prolongation in a middle-aged woman: a case report and literature review. Gen Hosp Psychiatry 34(210):e213-e215
    • (2012) Gen Hosp Psychiatry , vol.34 , Issue.210
    • Tseng, P.T.1    Lee, Y.2    Lin, Y.E.3    Lin, P.Y.4
  • 30
    • 0037266206 scopus 로고    scopus 로고
    • Escitalopram: A review of its use in the management of major depressive and anxiety disorders
    • 1:CAS:528:DC%2BD2MXoslGjurY%3D 12665392 10.2165/00023210-200317050-00004
    • Waugh J, Goa KL (2003) Escitalopram: a review of its use in the management of major depressive and anxiety disorders. CNS Drugs 17:343-362
    • (2003) CNS Drugs , vol.17 , pp. 343-362
    • Waugh, J.1    Goa, K.L.2
  • 31
    • 0037070199 scopus 로고    scopus 로고
    • Inhibitory actions of the selective serotonin re-uptake inhibitor citalopram on HERG and ventricular L-type calcium currents
    • 1:CAS:528:DC%2BD38XhtlGht7g%3D 11852052 10.1016/S0014-5793(01)03320-8
    • Witchel HJ, Pabbathi VK, Hofmann G, Paul AA, Hancox JC (2002) Inhibitory actions of the selective serotonin re-uptake inhibitor citalopram on HERG and ventricular L-type calcium currents. FEBS Lett 512:59-66
    • (2002) FEBS Lett , vol.512 , pp. 59-66
    • Witchel, H.J.1    Pabbathi, V.K.2    Hofmann, G.3    Paul, A.A.4    Hancox, J.C.5
  • 32
    • 84875064164 scopus 로고    scopus 로고
    • Mitral and tufted cells are potential cellular targets of nitration in the olfactory bulb of aged mice
    • 1:CAS:528:DC%2BC3sXltFSnu70%3D 3601056 23527248 10.1371/journal.pone. 0059673
    • Yang MJ, Sim S, Jeon JH, Jeong E, Kim HC, Park YJ, Kim IB (2013) Mitral and tufted cells are potential cellular targets of nitration in the olfactory bulb of aged mice. PLoS One 8:e59673
    • (2013) PLoS One , vol.8 , pp. 59673
    • Yang, M.J.1    Sim, S.2    Jeon, J.H.3    Jeong, E.4    Kim, H.C.5    Park, Y.J.6    Kim, I.B.7
  • 33
    • 40849083799 scopus 로고    scopus 로고
    • Inhibition of the cardiac L-type calcium channel current by antidepressant drugs
    • 1:CAS:528:DC%2BD1cXivVajs70%3D 18048694 10.1124/jpet.107.132456
    • Zahradnik I, Minarovic I, Zahradnikova A (2008) Inhibition of the cardiac L-type calcium channel current by antidepressant drugs. J Pharmacol Exp Ther 324:977-984
    • (2008) J Pharmacol Exp Ther , vol.324 , pp. 977-984
    • Zahradnik, I.1    Minarovic, I.2    Zahradnikova, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.