Xiao-Xu-Ming decoction preserves mitochondrial integrity and reduces apoptosis after focal cerebral ischemia and reperfusion via the mitochondrial p53 pathway

Journal of Ethnopharmacology

Volumn 151, Issue 1, 2014, Pages 307-316

  Lan, Rui ^a   Zhang, Yong ^b   Xiang, Jun ^a,c   Zhang, Wen ^a   Wang, Guo Hua ^a   Li, Wen Wei ^a   Xu, Li Li ^a   Cai, Ding Fang ^a  

^a FUDAN UNIVERSITY   (China)

^b GUANGZHOU UNIVERSITY OF CHINESE MEDICINE   (China)

^c SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Apoptosis; Focal cerebral ischemia and reperfusion; Mitochondria integrity; Mitochondrial p53 pathway; Xiao Xu Ming decoction

Indexed keywords

CASPASE 3; CASPASE 9; CYTOCHROME C; EOSIN; HEMATOXYLIN; HERBACEOUS AGENT; MITOCHONDRIAL PROTEIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; UNCLASSIFIED DRUG; XIAO XU MING DECOCTION;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CORTEX; BRAIN ISCHEMIA; BRAIN MITOCHONDRION; CELL PROTECTION; CELL ULTRASTRUCTURE; CHINESE HERB; CONTROLLED STUDY; CYTOPLASM; DRUG EFFECT; ENZYME ACTIVATION; HISTOPATHOLOGY; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NICK END LABELING; NONHUMAN; PROTEIN EXPRESSION; PROTEIN SECRETION; RAT; REPERFUSION INJURY; SIGNAL TRANSDUCTION; STAINING; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING;

RATTUS;

APOPTOSIS; FOCAL CEREBRAL ISCHEMIA AND REPERFUSION; MITOCHONDRIA INTEGRITY; MITOCHONDRIAL P53 PATHWAY; XIAO-XU-MING DECOCTION;

ANIMALS; APOPTOSIS; BRAIN ISCHEMIA; DRUGS, CHINESE HERBAL; GENE EXPRESSION REGULATION; MALE; MITOCHONDRIA; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84891490835     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2013.10.042     Document Type: Article

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