The association between negative affect and prescription opioid misuse in patients with chronic pain: The mediating role of opioid craving

Journal of Pain

Volumn 15, Issue 1, 2014, Pages 90-100

  Martel, Marc O ^a   Dolman, Andrew J ^a   Edwards, Robert R ^a   Jamison, Robert N ^a   Wasan, Ajay D ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Chronic pain; negative affect; opioid craving; prescription opioid misuse

Indexed keywords

OPIATE;

ADULT; AFFECT; ARTICLE; BACKACHE; CHRONIC PAIN; DRUG MISUSE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; NECK PAIN; NEGATIVE AFFECT; NEUROBIOLOGY; PHYSICAL EXAMINATION; PRESCRIPTION; PRESCRIPTION OPIOID MISUSE; PSYCHOLOGICAL ASPECT; SELF REPORT; WITHDRAWAL SYNDROME;

CHRONIC PAIN; NEGATIVE AFFECT; OPIOID CRAVING; PRESCRIPTION OPIOID MISUSE;

ADULT; ANALGESICS, OPIOID; CHRONIC PAIN; DRUG-SEEKING BEHAVIOR; FEMALE; HUMANS; MALE; MIDDLE AGED; OPIOID-RELATED DISORDERS; PAIN MEASUREMENT; PRESCRIPTION DRUGS; QUESTIONNAIRES; SELF REPORT; STATISTICS AS TOPIC;

EID: 84891487013     PISSN: 15265900     EISSN: 15288447     Source Type: Journal    
DOI: 10.1016/j.jpain.2013.09.014     Document Type: Article

References (95)

1. K.M. Abel, V. O'Keane, R.M. Murray, and A.J. Cleare Serotonergic function and negative and depressive symptomatology in schizophrenia and major depression Psychoneuroendocrinology 22 1997 539 548 (Pubitemid 27505113)
2. L.L. Adams, R.J. Gatchel, R.C. Robinson, P. Polatin, N. Gajraj, M. Deschner, and C. Noe Development of a self-report screening instrument for assessing potential opioid medication misuse in chronic pain patients J Pain Symptom Manage 27 2004 440 459 (Pubitemid 38569650)
3. G. Affleck, H. Tennen, S. Urrows, and P. Higgins Person and contextual features of daily stress reactivity: Individual differences in relations of undesirable daily events with mood disturbance and chronic pain intensity J Pers Soc Psychol 66 1994 329 340
4. American Academy of Pain Medicine, The American Society of Addiction Medicine Definitions related to the use of opioids for the treatment of pain: A consensus document from the American Academy of Pain Medicine, the American Pain Society, and the American Society of Addiction Medicine 2001 American Society of Addiction Medicine Chevy Chase, MD
5. American Psychological Association Diagnostic and Statistical Manual of Mental Disorders 4th ed. 2000 APA Washington, DC
6. T.B. Baker, M.E. Piper, D.E. McCarthy, M.R. Majeskie, and M.C. Fiore Addiction motivation reformulated: An affective processing model of negative reinforcement Psychol Rev 111 2004 33 51 (Pubitemid 38157073)
7. J.C. Ballantyne Opioid controls: Regulate to educate Pain Med 11 2010 480 481
8. J.C. Ballantyne, and K.S. LaForge Opioid dependence and addiction during opioid treatment of chronic pain Pain 129 2007 235 255 (Pubitemid 46754581)
9. R.M. Baron, and D.A. Kenny The moderator-mediator variable distinction in social psychological research: Conceptual, strategic, and statistical considerations J Pers Soc Psychol 51 1986 1173 1182
10. A.T. Beck, C.F. Newman, and B.S. Liese Cognitive Therapy of Substance Abuse 1993 Guilford Press New York
11. W.C. Becker, L.E. Sullivan, J.M. Tetrault, R.A. Desai, and D.A. Fiellin Non-medical use, abuse and dependence on prescription opioids among U.S. adults: Psychiatric, medical and substance use correlates Drug Alcohol Depend 94 2008 38 47
12. J.W. Burns, P. Quartana, W. Gilliam, E. Gray, J. Matsuura, C. Nappi, B. Wolfe, and K. Lofland Effects of anger suppression on pain severity and pain behaviors among chronic pain patients: Evaluation of an ironic process model Health Psychol 27 2008 645 652
13. S.F. Butler, S.H. Budman, G.J. Fanciullo, and R.N. Jamison Cross validation of the current opioid misuse measure to monitor chronic pain patients on opioid therapy Clin J Pain 26 2010 770 776
14. S.F. Butler, S.H. Budman, K. Fernandez, and R.N. Jamison Validation of a screener and opioid assessment measure for patients with chronic pain Pain 112 2004 65 75 (Pubitemid 39371021)
15. S.F. Butler, S.H. Budman, K.C. Fernandez, B. Houle, C. Benoit, N. Katz, and R.N. Jamison Development and validation of the Current Opioid Misuse Measure Pain 130 2007 144 156 (Pubitemid 46843461)
16. S.F. Butler, K. Fernandez, C. Benoit, S.H. Budman, and R.N. Jamison Validation of the revised Screener and Opioid Assessment for Patients with Pain (SOAPP-R) J Pain 9 2008 360 372
17. S.L. Catz, J.A. Kelly, L.M. Bogart, E.G. Benotsch, and T.L. McAuliffe Patterns, correlates, and barriers to medication adherence among persons prescribed new treatments for HIV disease Health Psychol 19 2000 124 133
18. C. Chabal, M.K. Erjavec, L. Jacobson, A. Mariano, and E. Chaney Prescription opiate abuse in chronic pain patients: Clinical criteria, incidence, and predictors Clin J Pain 13 1997 150 155 (Pubitemid 27251109)
19. A.R. Childress, R. Ehrman, A.T. McLellan, J. MacRae, M. Natale, and C.P. O'Brien Can induced moods trigger drug-related responses in opiate abuse patients? J Subst Abuse Treat 11 1994 17 23 (Pubitemid 24113136)
20. R. Chou, G.J. Fanciullo, P.G. Fine, C. Miaskowski, S.D. Passik, and R.K. Portenoy Opioids for chronic noncancer pain: Prediction and identification of aberrant drug-related behaviors: A review of the evidence for an American Pain Society and American Academy of Pain Medicine clinical practice guideline J Pain 10 2009 131 146
21. R. Ciccocioppo The role of serotonin in craving: From basic research to human studies Alcohol Alcohol 34 1999 244 253 (Pubitemid 29213718)
22. P. Compton, J. Darakjian, and K. Miotto Screening for addiction in patients with chronic pain and "problematic" substance use: Evaluation of a pilot assessment tool J Pain Symptom Manage 16 1998 355 363 (Pubitemid 29006198)
23. H. de Wit Impulsivity as a determinant and consequence of drug use: A review of underlying processes Addict Biol 14 2009 22 31
24. D.C. Drummond Theories of drug craving, ancient and modern Addiction 96 2001 33 46 (Pubitemid 32099338)
25. J. Dunbar-Jacob, and M.K. Mortimer-Stephens Treatment adherence in chronic disease J Clin Epidemiol 54 Suppl 1 2001 S57 S60
26. M.J. Edlund Chronic opioid therapy for chronic noncancer pain in the United States: Long Day's Journey into Night? Gen Hosp Psychiatry 33 2011 416 418
27. M.J. Edlund, M. Sullivan, D. Steffick, K.M. Harris, and K.B. Wells Do users of regularly prescribed opioids have higher rates of substance use problems than nonusers? Pain Med 8 2007 647 656 (Pubitemid 350142912)
28. D.H. Epstein, J. Willner-Reid, M. Vahabzadeh, M. Mezghanni, J.L. Lin, and K.L. Preston Real-time electronic diary reports of cue exposure and mood in the hours before cocaine and heroin craving and use Arch Gen Psychiatry 66 2009 88 94
29. S. Erhardt, S.K. Olsson, and G. Engberg Pharmacological manipulation of kynurenic acid: Potential in the treatment of psychiatric disorders CNS Drugs 23 2009 91 101
30. K.D. Ersche, A.J. Turton, S. Pradhan, E.T. Bullmore, and T.W. Robbins Drug addiction endophenotypes: Impulsive versus sensation-seeking personality traits Biol Psychiatry 68 2010 770 773
31. V.G. Frokjaer, E.L. Mortensen, F.A. Nielsen, S. Haugbol, L.H. Pinborg, K.H. Adams, C. Svarer, S.G. Hasselbalch, S. Holm, O.B. Paulson, and G.M. Knudsen Frontolimbic serotonin 2A receptor binding in healthy subjects is associated with personality risk factors for affective disorder Biol Psychiatry 63 2008 569 576 (Pubitemid 351273195)
32. V.G. Frokjaer, M. Vinberg, D. Erritzoe, W. Baare, K.K. Holst, E.L. Mortensen, H. Arfan, J. Madsen, T.L. Jernigan, L.V. Kessing, and G.M. Knudsen Familial risk for mood disorder and the personality risk factor, neuroticism, interact in their association with frontolimbic serotonin 2A receptor binding Neuropsychopharmacology 35 2010 1129 1137
33. K. Gao, D.E. Kemp, C. Conroy, S.J. Ganocy, R.L. Findling, and J.R. Calabrese Comorbid anxiety and substance use disorders associated with a lower use of mood stabilisers in patients with rapid cycling bipolar disorder: A descriptive analysis of the cross-sectional data of 566 patients Int J Clin Pract 64 2010 336 344
34. R.J. Gatchel, Y.B. Peng, M.L. Peters, P.N. Fuchs, and D.C. Turk The biopsychosocial approach to chronic pain: Scientific advances and future directions Psychol Bull 133 2007 581 624
35. K.M. Gil, J.W. Carson, L.S. Porter, C. Scipio, S.M. Bediako, and E. Orringer Daily mood and stress predict pain, health care use, and work activity in African American adults with sickle-cell disease Health Psychol 23 2004 267 274 (Pubitemid 38542358)
36. A. Grattan, M.D. Sullivan, K.W. Saunders, C.I. Campbell, and M.R. Von Korff Depression and prescription opioid misuse among chronic opioid therapy recipients with no history of substance abuse Ann Fam Med 10 2012 304 311
37. A. Hayes Beyond Baron and Kenny: Statistical mediation analysis in the new millennium Communication Monographs 76 2009 408 420
38. B.D. Heckman, S.L. Catz, T.G. Heckman, J.G. Miller, and S.C. Kalichman Adherence to antiretroviral therapy in rural persons living with HIV disease in the United States AIDS Care 16 2004 219 230 (Pubitemid 38183585)
39. S.M. Hyman, H. Fox, K.I. Hong, C. Doebrick, and R. Sinha Stress and drug-cue-induced craving in opioid-dependent individuals in naltrexone treatment Exp Clin Psychopharmacol 15 2007 134 143 (Pubitemid 47445242)
40. T.J. Ives, P.R. Chelminski, C.A. Hammett-Stabler, R.M. Malone, J.S. Perhac, N.M. Potisek, B.B. Shilliday, D.A. DeWalt, and M.P. Pignone Predictors of opioid misuse in patients with chronic pain: A prospective cohort study BMC Health Serv Res 6 2006 46
41. J.P. Jacobsen, I.O. Medvedev, and M.G. Caron The 5-HT deficiency theory of depression: Perspectives from a naturalistic 5-HT deficiency model, the tryptophan hydroxylase 2Arg439His knockin mouse Philos Trans R Soc Lond B Biol Sci 367 2012 2444 2459
42. R.N. Jamison, R.R. Edwards, X. Liu, E.L. Ross, E. Michna, M. Warnick, and A.D. Wasan Relationship of negative affect and outcome of an opioid therapy trial among low back pain patients Pain Pract 13 2013 173 181
43. R.N. Jamison, C.L. Link, and L.D. Marceau Do pain patients at high risk for substance misuse experience more pain? A longitudinal outcomes study Pain Med 10 2009 1084 1094
44. R.N. Jamison, S.A. Raymond, J.G. Levine, E.A. Slawsby, S.S. Nedeljkovic, and N.P. Katz Electronic diaries for monitoring chronic pain: 1-year validation study Pain 91 2001 277 285 (Pubitemid 32241149)
45. R.N. Jamison, E.L. Ross, E. Michna, L.Q. Chen, C. Holcomb, and A.D. Wasan Substance misuse treatment for high-risk chronic pain patients on opioid therapy: A randomized trial Pain 150 2010 390 400
46. R.N. Jamison, J. Serraillier, and E. Michna Assessment and treatment of abuse risk in opioid prescribing for chronic pain Pain Res Treat 2011 941808 2011
47. M.P. Jensen, J.A. Turner, J.M. Romano, and P. Karoly Coping with chronic pain: A critical review of the literature Pain 47 1991 249 283
48. G.F. Koob A role for brain stress systems in addiction Neuron 59 2008 11 34 (Pubitemid 351905857)
49. G.F. Koob, and N.D. Volkow Neurocircuitry of addiction Neuropsychopharmacology 35 2010 217 238
50. D.P. MacKinnon, A.J. Fairchild, and M.S. Fritz Mediation analysis Annu Rev Psychol 58 2007 593 614
51. D.P. MacKinnon, C.M. Lockwood, J.M. Hoffman, S.G. West, and V. Sheets A comparison of methods to test mediation and other intervening variable effects Psychol Methods 7 2002 83 104
52. L. Manchikanti, J. Giordano, M.V. Boswell, B. Fellows, R. Manchukonda, and V. Pampati Psychological factors as predictors of opioid abuse and illicit drug use in chronic pain patients J Opioid Manag 3 2007 89 100 (Pubitemid 46760149)
53. L.D. Marceau, C. Link, R.N. Jamison, and S. Carolan Electronic diaries as a tool to improve pain management: Is there any evidence? Pain Med 8 Suppl 3 2007 S101 S109
54. G.A. Marlatt Cue exposure and relapse prevention in the treatment of addictive behaviors Addict Behav 15 1990 395 399 (Pubitemid 20302492)
55. E. Michna, E.L. Ross, W.L. Hynes, S.S. Nedeljkovic, S. Soumekh, D. Janfaza, D. Palombi, and R.N. Jamison Predicting aberrant drug behavior in patients treated for chronic pain: Importance of abuse history J Pain Symptom Manage 28 2004 250 258 (Pubitemid 39158807)
56. F.G. Moeller, D.M. Dougherty, E.S. Barratt, J.M. Schmitz, A.C. Swann, and J. Grabowski The impact of impulsivity on cocaine use and retention in treatment J Subst Abuse Treat 21 2001 193 198 (Pubitemid 34037109)
57. C. O'Brien Addiction and dependence in DSM-V Addiction 106 2011 866 867
58. C.P. O'Brien Anticraving medications for relapse prevention: A possible new class of psychoactive medications Am J Psychiatry 162 2005 1423 1431 (Pubitemid 41105556)
59. C.P. O'Brien Review. Evidence-based treatments of addiction Philos Trans R Soc Lond B Biol Sci 363 2008 3277 3286
60. S.D. Passik, and L. Webster Pseudoaddiction revisited: A commentary on clinical and historical considerations Pain Management 1 2011 239 248
61. S.D. Passik, and K.L. Kirsh Addictions in pain clinics and pain treatment Ann N Y Acad Sci 1216 2011 138 143
62. K.J. Preacher, and A.F. Hayes SPSS and SAS procedures for estimating indirect effects in simple mediation models Behav Res Methods Instrum Comput 36 2004 717 731 (Pubitemid 40251423)
63. K.J. Preacher, and A.F. Hayes Asymptotic and resampling strategies for assessing and comparing indirect effects in multiple mediator models Behav Res Methods 40 2008 879 891
64. S.E. Reme, T. Tangen, T. Moe, and H.R. Eriksen Prevalence of psychiatric disorders in sick listed chronic low back pain patients Eur J Pain 15 2011 1075 1080
65. T.E. Robinson, and K.C. Berridge The neural basis of drug craving: An incentive-sensitization theory of addiction Brain Res Brain Res Rev 18 1993 247 291 (Pubitemid 23219500)
66. B.M. Schieffer, Q. Pham, J. Labus, A. Baria, W. Van Vort, P. Davis, F. Davis, and B.D. Naliboff Pain medication beliefs and medication misuse in chronic pain J Pain 6 2005 620 629
67. S. Passik, and K. Kirsch Pain in the substance abuse population H. Smith, Current Therapy in Pain 2009 Saunders Elsevier Press Philadelphia, PA 392 395
68. N. Sehgal, L. Manchikanti, and H.S. Smith Prescription opioid abuse in chronic pain: A review of opioid abuse predictors and strategies to curb opioid abuse Pain Physician 15 2012 ES67 ES92
69. Sheehan DV, Lecrubier Y, Sheehan KH, Amorim P, Janavs J, Weiller E, Hergueta T, Baker R, Dunbar GC: The Mini-International Neuropsychiatric Interview (M.I.N.I.): The development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J Clin Psychiatry 59 (Suppl 20):22-33;quiz 34-57, 1998
70. P.E. Shrout, and N. Bolger Mediation in experimental and nonexperimental studies: New procedures and recommendations Psychol Methods 7 2002 422 445
71. R. Sinha Modeling stress and drug craving in the laboratory: Implications for addiction treatment development Addict Biol 14 2009 84 98
72. R. Sinha, D. Catapano, and S. O'Malley Stress-induced craving and stress response in cocaine dependent individuals Psychopharmacology (Berl) 142 1999 343 351 (Pubitemid 29187622)
73. R. Sinha, M. Garcia, P. Paliwal, M.J. Kreek, and B.J. Rounsaville Stress-induced cocaine craving and hypothalamic-pituitary-adrenal responses are predictive of cocaine relapse outcomes Arch Gen Psychiatry 63 2006 324 331 (Pubitemid 43345357)
74. M.D. Skinner, and H.J. Aubin Craving's place in addiction theory: Contributions of the major models Neurosci Biobehav Rev 34 2010 606 623
75. B.L. Smalls, R.J. Walker, M.A. Hernandez-Tejada, J.A. Campbell, K.S. Davis, and L.E. Egede Associations between coping, diabetes knowledge, medication adherence and self-care behaviors in adults with type 2 diabetes Gen Hosp Psychiatry 34 2012 385 389
76. M.D. Sullivan, and J.C. Ballantyne What are we treating with long-term opioid therapy? Arch Intern Med 172 2012 433 434
77. M.D. Sullivan, M.J. Edlund, M.Y. Fan, A. Devries, J. Brennan Braden, and B.C. Martin Risks for possible and probable opioid misuse among recipients of chronic opioid therapy in commercial and medicaid insurance plans: The TROUP Study Pain 150 2010 332 339
78. R.M. Swift, and R.L. Stout The relationship between craving, anxiety, and other symptoms in opioid withdrawal J Subst Abuse 4 1992 19 26
79. N.K. Tang, P.M. Salkovskis, A. Hodges, K.J. Wright, M. Hanna, and J. Hester Effects of mood on pain responses and pain tolerance: An experimental study in chronic back pain patients Pain 138 2008 392 401
80. S.T. Tiffany, E. Singleton, C.A. Haertzen, and J.E. Henningfield The development of a cocaine craving questionnaire Drug Alcohol Depend 34 1993 19 28 (Pubitemid 24036387)
81. S.T. Tiffany, and J.M. Wray The clinical significance of drug craving Ann N Y Acad Sci 1248 2012 1 17
82. D.C. Turk, K.S. Swanson, and R.J. Gatchel Predicting opioid misuse by chronic pain patients: A systematic review and literature synthesis Clin J Pain 24 2008 497 508
83. D. Tziortzis, J.J. Mahoney 3rd, A.D. Kalechstein, T.F. Newton, and R. De la Garza 2nd The relationship between impulsivity and craving in cocaine- and methamphetamine-dependent volunteers Pharmacol Biochem Behav 98 2011 196 202
84. R. Verheul, W. van den Brink, and P. Geerlings A three-pathway psychobiological model of craving for alcohol Alcohol Alcohol 34 1999 197 222 (Pubitemid 29213715)
85. A.D. Wasan, S.F. Butler, S.H. Budman, C. Benoit, K. Fernandez, and R.N. Jamison Psychiatric history and psychologic adjustment as risk factors for aberrant drug-related behavior among patients with chronic pain Clin J Pain 23 2007 307 315 (Pubitemid 46650023)
86. A.D. Wasan, S.F. Butler, S.H. Budman, K. Fernandez, R.D. Weiss, S.F. Greenfield, and R.N. Jamison Does report of craving opioid medication predict aberrant drug behavior among chronic pain patients? Clin J Pain 25 2009 193 198
87. A.D. Wasan, G. Davar, and R. Jamison The association between negative affect and opioid analgesia in patients with discogenic low back pain Pain 117 2005 450 461 (Pubitemid 41383540)
88. A.D. Wasan, R.N. Jamison, L. Pham, N. Tipirneni, S.S. Nedeljkovic, and J.N. Katz Psychopathology predicts the outcome of medial branch blocks with corticosteroid for chronic axial low back or cervical pain: A prospective cohort study BMC Musculoskelet Disord 10 2009 22
89. A.D. Wasan, E.L. Ross, E. Michna, L. Chibnik, S.F. Greenfield, R.D. Weiss, and R.N. Jamison Craving of prescription opioids in patients with chronic pain: A longitudinal outcomes trial J Pain 13 2012 146 154
90. L.R. Webster, and R.M. Webster Predicting aberrant behaviors in opioid-treated patients: Preliminary validation of the Opioid Risk Tool Pain Med 6 2005 432 442 (Pubitemid 43110296)
91. F. Weiss Neurobiology of craving, conditioned reward and relapse Curr Opin Pharmacol 5 2005 9 19 (Pubitemid 40124529)
92. R.D. Weiss, M.L. Griffin, C. Mazurick, B. Berkman, D.R. Gastfriend, A. Frank, J.P. Barber, J. Blaine, I. Salloum, and K. Moras The relationship between cocaine craving, psychosocial treatment, and subsequent cocaine use Am J Psychiatry 160 2003 1320 1325 (Pubitemid 41070950)
93. C.A. Winstanley, P. Olausson, J.R. Taylor, and J.D. Jentsch Insight into the relationship between impulsivity and substance abuse from studies using animal models Alcohol Clin Exp Res 34 2010 1306 1318
94. S.M. Wu, P. Compton, R. Bolus, B. Schieffer, Q. Pham, A. Baria, W. Van Vort, F. Davis, P. Shekelle, and B.D. Naliboff The addiction behaviors checklist: Validation of a new clinician-based measure of inappropriate opioid use in chronic pain J Pain Symptom Manage 32 2006 342 351 (Pubitemid 44430131)
95. A.J. Zautra, L.M. Johnson, and M.C. Davis Positive affect as a source of resilience for women in chronic pain J Consult Clin Psychol 73 2005 212 220 (Pubitemid 40446376)