Temporal production of the signaling lipid phosphatidic acid by phospholipase D2 determines the output of extracellular signal-regulated kinase signaling in cancer cells

Molecular and Cellular Biology

Volumn 34, Issue 1, 2014, Pages 84-95

  Wang, Feng Zhang ^a   Lu, Maryia ^a   Liang, Yoshiya Yonekubo ^a,b   Zhang, Yueqiang ^a   Wu, Ping ^a   Zhou, Yong ^a   Grinstein, Sergio ^c   Hancock, John F ^a   Du, Guangwei ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDIC ACID; PHOSPHOLIPASE D2; TRANSCRIPTION FACTOR ELK 1; TRANSCRIPTION FACTOR FRA 1;

ANIMAL CELL; ARTICLE; BIOSENSOR; BREAST CANCER; CANCER CELL; CANCER CELL CULTURE; CELL GROWTH; CELL NUCLEUS; CELL PROLIFERATION; ENZYME ACTIVATION; ENZYME INHIBITION; INTRACELLULAR SIGNALING; NONHUMAN; ONCOGENE C FOS; PHOSPHATIDIC ACID BIOSENSOR WITH SUPERIOR SENSITIVITY; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; SIGNAL TRANSDUCTION;

ANIMALS; BINDING SITES; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL MEMBRANE; CELL NUCLEUS; CELL PROLIFERATION; CHO CELLS; CRICETINAE; CRICETULUS; DIACYLGLYCEROL KINASE; EPIDERMAL GROWTH FACTOR; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GREEN FLUORESCENT PROTEINS; HEK293 CELLS; HUMANS; LUMINESCENT PROTEINS; MICROSCOPY, CONFOCAL; NEOPLASMS; PHOSPHATIDIC ACIDS; PHOSPHOLIPASE D; QB-SNARE PROTEINS; QC-SNARE PROTEINS; RNA INTERFERENCE; SACCHAROMYCES CEREVISIAE PROTEINS; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 84891437205     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00987-13     Document Type: Article

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