Inappropriate exercise-induced increase in pulmonary artery pressure in patients with systemic sclerosis

Heart

Volumn 97, Issue 2, 2011, Pages 112-117

  D'Alto, Michele ^a   Ghio, Stefano ^b   D'Andrea, Antonello ^a   Pazzano, Anna Sara ^b   Argiento, Paola ^a   Camporotondo, Rita ^b   Allocca, Francesca ^a   Scelsi, Laura ^b   Cuomo, Giovanna ^a   Caporali, Roberto ^b   Cavagna, Lorenzo ^b   Valentini, Gabriele ^a   Calabrò, Raffaele ^a  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

^b FONDAZIONE IRCCS POLICLINICO SAN MATTEO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CONTROLLED STUDY; DIASTOLIC DYSFUNCTION; ECHOCARDIOGRAPHY; EXERCISE; EXERCISE TEST; FEMALE; HEART RIGHT VENTRICLE FUNCTION; HUMAN; LUNG ARTERY PRESSURE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PULMONARY HYPERTENSION; STRESS ECHOCARDIOGRAPHY; SYSTEMIC SCLEROSIS; TRICUSPID VALVE REGURGITATION;

ADULT; AGED; BLOOD PRESSURE; DIASTOLE; ECHOCARDIOGRAPHY; EXERCISE; FEASIBILITY STUDIES; FEMALE; HUMANS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; PULMONARY ARTERY; SCLERODERMA, SYSTEMIC; SYSTOLE; VENTRICULAR FUNCTION, RIGHT;

EID: 78651247949     PISSN: 13556037     EISSN: 1468201X     Source Type: Journal    
DOI: 10.1136/hrt.2010.203471     Document Type: Article

References (30)

1. Anon. Preliminary criteria for the classification of systemic sclerosis (scleroderma) Subcommittee for Scleroderma Criteria of the American Rheumatism Association Diagnostic Therapeutic Criteria Committee. Arthritis Rheum 1980;23:581-90.
2. Steen V. Advancements in diagnosis of pulmonary arterial hypertension in scleroderma. Arthritis Rheum 2005;52:3698-700.
3. Galiè N, Rubin LJ, Hoeper MM, et al. Treatment of patients with mildly symptomatic pulmonary arterial hypertension with bosentan (EARLY study): a double-blind, randomised controlled trial. Lancet 2008;371:2093-100. (Pubitemid 351902178)
4. Galiè N, Hoeper MM, Humbert M, et al. Guidelines for the diagnosis and treatment of pulmonary hypertension. Eur Heart J 2009;30:2493-537.
5. Mukerjee D, St George D, Knight C, et al. Echocardiography and pulmonary function as screening tests for pulmonary arterial hypertension in systemic sclerosis. Rheumatology 2004;43:461-6.
6. Hachulla E, Gressin V, Guillevin L, et al. Early detection of pulmonary arterial hypertension in systemic sclerosis: a French nationwide prospective multicenter study. Arthritis Rheum 2005;52:3792-800.
7. Williams MH, Handler CE, Akram R, et al. Role of N-terminal brain natriuretic peptide (N-TproBNP) in scleroderma-associated pulmonary arterial hypertension. Eur Heart J 2006;27:1485-94.
8. Allanore Y, Borderie D, Avouac J, et al. High N-terminal pro-brain natriuretic peptide levels and low diffusing capacity for carbon monoxide as independent predictors of the occurrence of precapillary pulmonary arterial hypertension in patients with systemic sclerosis. Arthritis Rheum 2008;58:284-91.
9. Steen V, Medsger TA Jr. Predictors of isolated pulmonary hypertension in patients with systemic sclerosis and limited cutaneous involvement. Arthritis Rheum 2003;48:516-22.
10. Yamane K, Ihn H, Asano Y, et al. Clinical and laboratory features of scleroderma patients with pulmonary hypertension. Rheumatology 2000;39:1269-71.
11. Black C. Pulmonary arterial hypertension: are we doing enough to identify systemic sclerosis patients at high risk of this rare condition? Rheumatology 2005;44:141-2.
12. Bossone E, Rubenfire M, Bach DS, et al. Range of tricuspid regurgitation velocity at rest and during exercise in normal adult men: implications for the diagnosis of pulmonary hypertension. J Am Coll Cardiol 1999;33:1662-6.
13. Argiento P, Chesler N, Mulè M, et al. Exercise stress echocardiography for the study of the pulmonary circulation. Eur Respir J 2010;35:1273-8.
14. Raeside DA, Brown A, Patel KR, et al. Ambulatory pulmonary artery pressure monitoring during sleep and exercise in normal individuals and patients with COPD. Thorax 2002;57:1050-3.
15. Himelman RB, Stulbarg M, Kircher B, et al. Noninvasive evaluation of pulmonary artery pressure during exercise by saline-enhanced Doppler echocardiography in chronic pulmonary disease. Circulation 1989;79:863-71.
16. Steen V, Chou M, Shanmugam V, et al. Exercise-induced pulmonary arterial hypertension in patients with systemic sclerosis. Chest 2008;134:146-51.
17. Reichenberger F, Voswinckel R, Schulz R, et al. Noninvasive detection of early pulmonary vascular dysfunction in scleroderma. Respir Med 2009;103:1713-18.
18. Valentini G, Medsger TA Jr, Silman AJ, et al. Conclusion and identification of the core set of variables to be used in clinical investigations. Clin Exp Rheumatol 2003;21(3 Suppl 29):S47-8.
19. Valentini G, Bencivelli W, Bombardieri S, et al. European Scleroderma Study Group to define disease activity criteria for systemic sclerosis. III. Assessment of the construct validity of the preliminary activity criteria. Ann Rheum Dis 2003;62:901-3.
20. Kazerooni EA, Martinez FJ, Flint A, et al. Thin-section CT obtained at 10-mm increments versus limited three-level thin-section CT for idiopathic pulmonary fibrosis: correlation with pathologic scoring. AJR Am J Roentgenol 1997;169:977-83.
21. Kovacs G, Maier R, Aberer E, et al. Borderline pulmonary arterial pressure is associated with decreased exercise capacity in scleroderma. Am J Respir Crit Care Med 2009;180:881-6.
22. Naeije R, Huez S. Right ventricular function in pulmonary hypertension: physiological concepts. Eur Heart J Suppl 2007;9:H5-9.
23. Huez S, Roufosse F, Vachiéry JL, et al. Isolated right ventricular dysfunction in systemic sclerosis: latent pulmonary hypertension? Eur Respir J 2007; 30:928-36.
24. Al-Sabbagh MR, Steen VD, Zee BC, et al. Pulmonary arterial histology and morphometry in systemic sclerosis: a case-control autopsy study. J Rheumatol 1989;16:1038-42.
25. Naeije R, Huez S, Lamotte M, et al. Pulmonary artery pressure limits exercise capacity at high altitude. Eur Respir J 2010;5:1049-55.
26. Ghofrani HA, Reichenberger F, Kohstall MG, et al. Sildenafil increased exercise capacity during hypoxia at low altitudes and at Mount Everest base camp: a randomized, double-blind, placebo-controlled crossover trial. Ann Intern Med 2004;141:169-77.
27. Grünig E, Weissmann S, Ehlken N, et al. Stress Doppler echocardiography in relatives of patients with idiopathic and familial pulmonary arterial hypertension: results of a multicenter European analysis of pulmonary artery pressure response to exercise and hypoxia. Circulation 2009;119:1747-57.
28. Giunta A, Tirri E, Maione S, et al. Right ventricular diastolic abnormalities in systemic sclerosis. Relation to left ventricular involvement and pulmonary hypertension. Ann Rheum Dis 2000;59:94-8.
29. Plazak W, Zabinska-Plazak E, Wojas Pelc A, et al. Heart structure and function in systemic sclerosis. Eur J Dermatol 2002;12:257-62.
30. Valentini G, Vitale DF, Giunta A, et al. Diastolic abnormalities in systemic sclerosis: evidence for associated defective cardiac functional reserve. Ann Rheum Dis 1996;55:455-60. (Pubitemid 26249021)