Significant reduction in rate of indeterminate results of the QuantiFERON-TB gold in-tube test by shortening incubation delay

Journal of Clinical Microbiology

Volumn 52, Issue 1, 2014, Pages 90-94

  Yun, Jae Won ^a   Chung, Hae Sun ^b   Koh, Won Jung ^a   Chung, Doo Ryeon ^a   Kim, Yae Jean ^a   Kanga, Eun Suk ^a  

^a Sungkyunkwan University School of Medicine   (South Korea)

^b Ewha Womans University School of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; GAMMA INTERFERON; IMMUNOSUPPRESSIVE AGENT;

ADOLESCENT; ADULT; AGED; ALBUMIN BLOOD LEVEL; ARTICLE; AUTOIMMUNE DISEASE; CHILD; CHRONIC KIDNEY FAILURE; CONTROLLED STUDY; DIABETES MELLITUS; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HYPOALBUMINEMIA; IMMOBILITY; INCUBATION DELAY; INFANT; INJURY; LABORATORY TEST; LYMPHOCYTE COUNT; MAJOR CLINICAL STUDY; MAJOR SURGERY; MALE; MALIGNANT NEOPLASTIC DISEASE; MYCOBACTERIUM TUBERCULOSIS TEST KIT; PRIORITY JOURNAL; RETROSPECTIVE STUDY; TUBERCULOSIS; VERY ELDERLY;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; FEMALE; HUMANS; INTERFERON-GAMMA RELEASE TESTS; MALE; MIDDLE AGED; REPUBLIC OF KOREA; SENSITIVITY AND SPECIFICITY; SPECIMEN HANDLING; TERTIARY CARE CENTERS; TIME FACTORS; TUBERCULOSIS; YOUNG ADULT;

EID: 84891394977     PISSN: 00951137     EISSN: 1098660X     Source Type: Journal    
DOI: 10.1128/JCM.01547-13     Document Type: Article

References (14)

1. Ralph AP, Anstey NM, Kelly PM. 2009. Tuberculosis into the 2010s: Is the glass half full? Clin. Infect. Dis. 49:574-583. http://dx.doi.org/10.1086/ 600889.
2. Maartens G, Wilkinson RJ. 2007. Tuberculosis. Lancet 370:2030-2043. http://dx.doi.org/10.1016/S0140-6736(07)61262-8.
3. Horsburgh CR, Jr. 2004. Priorities for the treatment of latent tuberculosis infection in the United States. N. Engl. J. Med. 350:2060-2067. http://dx.doi.org/10.1056/NEJMsa031667.
4. Mazurek GH, Weis SE, Moonan PK, Daley CL, Bernardo J, Lardizabal AA, Reves RR, Toney SR, Daniels LJ, LoBue PA. 2007. Prospective comparison of the tuberculin skin test and 2 whole-blood interferongamma release assays in persons with suspected tuberculosis. Clin. Infect. Dis. 45:837-845. http://dx.doi.org/10.1086/521107.
5. Pai M, Riley LW, Colford JM, Jr. 2004. Interferon-gamma assays in the immunodiagnosis of tuberculosis: A systematic review. Lancet Infect. Dis. 4:761-776. http://dx.doi.org/10.1016/S1473-3099(04)01206-X.
6. Ferrara G, Losi M, D'Amico R, Roversi P, Piro R, Meacci M, Meccugni B, Dori IM, Andreani A, Bergamini BM, Mussini C, Rumpianesi F, Fabbri LM, Richeldi L. 2006. Use in routine clinical practice of two commercial blood tests for diagnosis of infection with Mycobacterium tuberculosis: A prospective study. Lancet 367:1328-1334. http://dx.doi.org/10.1016/S0140-6736(06)68579-6.
7. Kobashi Y, Mouri K, Obase Y, Fukuda M, Miyashita N, Oka M. 2007. Clinical evaluation of QuantiFERON TB-2G test for immunocompromised patients. Eur. Respir. J. 30:945-950. http://dx.doi.org/10.1183/09031936.00040007.
8. Cummings KJ, Smith TS, Shogren ES, Khakoo R, Nanda S, Bunner L, Smithmyer A, Soccorsi D, Kashon ML, Mazurek GH, Friedman LN, Weissman DN. 2009. Prospective comparison of tuberculin skin test and QuantiFERON-TB Gold In-Tube assay for the detection of latent tuberculosis infection among healthcare workers in a low-incidence setting. Infect. Control Hosp. Epidemiol. 30:1123-1126. http://dx.doi.org/10.1086/644754.
9. Lalvani A, Pareek M. 2010. Interferon gamma release assays: Principles and practice. Enferm. Infecc. Microbiol. Clin. 28:245-252. http://dx.doi.org/10. 1016/j.eimc.2009.05.012.
10. Miranda C, Yen-Lieberman B, Terpeluk P, Tomford JW, Gordon S. 2009. Reducing the rates of indeterminate results of the Quanti-FERON-TB Gold In-Tube test during routine preemployment screening for latent tuberculosis infection among healthcare personnel. Infect. Control Hosp. Epidemiol. 30:296-298. http://dx.doi.org/10.1086/595732.
11. Cho K, Cho E, Kwon S, Im S, Sohn I, Song S, Kim H, Kim S. 2012. Factors associated with indeterminate and false negative results of Quanti-FERON-TB Gold In-Tube test in active tuberculosis. Tuberc. Respir. Dis. (Seoul) 72:416-425. http://dx.doi.org/10.4046/trd.2012.72.5.416.
12. Kim EY, Lim JE, Jung JY, Son JY, Lee KJ, Yoon YW, Park BH, Moon JW, Park MS, Kim YS, Kim SK, Chang J, Kang YA. 2009. Performance of the tuberculin skin test and interferon-gamma release assay for detection of tuberculosis infection in immunocompromised patients in a BCGvaccinated population. BMC Infect. Dis. 9:207. http://dx.doi.org/10.1186/1471-2334-9-207.
13. Kobashi Y, Sugiu T, Mouri K, Obase Y, Miyashita N, Oka M. 2009. Indeterminate results of QuantiFERON TB-2G test performed in routine clinical practice. Eur. Respir. J. 33:812-815. http://dx.doi.org/10.1183/09031936. 00075008.
14. Herrera V, Yeh E, Murphy K, Parsonnet J, Banaei N. 2010. Immediate incubation reduces indeterminate results for QuantiFERON-TB Gold intube assay. J. Clin. Microbiol. 48:2672-2676. http://dx.doi.org/10.1128/JCM.00482-10.