메뉴 건너뛰기




Volumn 32, Issue , 2013, Pages 122-130

Characterization of the secretome of human tooth germ stem cells (hTGSCs) reveals neuro-protection by fine-tuning micro-environment

Author keywords

Bio active molecules; Cytokine; Human tooth germ stem cells (hTGSCs); Neuro protection; Secretome; Toxicity

Indexed keywords

AMYLOID BETA PROTEIN; BONE MORPHOGENETIC PROTEIN 2; CATALASE; CD34 ANTIGEN; EOTAXIN; FIBROBLAST GROWTH FACTOR 2; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GLUCOSE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MONOCYTE CHEMOTACTIC PROTEIN 1; OXIDOPAMINE; OXYGEN; RANTES; SUPEROXIDE DISMUTASE; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN;

EID: 84891373337     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2013.03.007     Document Type: Article
Times cited : (31)

References (36)
  • 1
    • 20444419744 scopus 로고    scopus 로고
    • Autologous mesenchymal stem cell transplantation in stroke patients
    • Bang, O.Y., Lee, J.S., et al., 2005. Autologous mesenchymal stem cell transplantation in stroke patients. Ann. Neurol. 57 (6), 874-882.
    • (2005) Ann. Neurol. , vol.57 , Issue.6 , pp. 874-882
    • Bang, O.Y.1    Lee, J.S.2
  • 2
    • 51349167276 scopus 로고    scopus 로고
    • Growth factors and cytokines in wound healing
    • Barrientos, S., Stojadinovic, O., et al., 2008. Growth factors and cytokines in wound healing. Wound Repair Regen. 16 (5), 585-601.
    • (2008) Wound Repair Regen. , vol.16 , Issue.5 , pp. 585-601
    • Barrientos, S.1    Stojadinovic, O.2
  • 3
    • 57049089034 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stem cells for the treatment of ischemic stroke
    • Dharmasaroja, P., 2009. Bone marrow-derived mesenchymal stem cells for the treatment of ischemic stroke. J. Clin. Neurosci. 16 (1), 12-20.
    • (2009) J. Clin. Neurosci. , vol.16 , Issue.1 , pp. 12-20
    • Dharmasaroja, P.1
  • 4
    • 84870333632 scopus 로고    scopus 로고
    • Differentiation of human stem cells is promoted by amphiphilic pluronic block copolymers
    • Dogan, A., Yalvaç, M.E., et al., 2012. Differentiation of human stem cells is promoted by amphiphilic pluronic block copolymers. Int. J. Nanomed. 7, 4849-4860.
    • (2012) Int. J. Nanomed. , vol.7 , pp. 4849-4860
    • Dogan, A.1    Yalvaç, M.E.2
  • 5
    • 44149114044 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells from healthy donors and sporadic amyotrophic lateral sclerosis patients
    • Ferrero, I., Mazzini, L., et al., 2008. Bone marrow mesenchymal stem cells from healthy donors and sporadic amyotrophic lateral sclerosis patients. Cell Transplant. 17 (3), 255-266.
    • (2008) Cell Transplant. , vol.17 , Issue.3 , pp. 255-266
    • Ferrero, I.1    Mazzini, L.2
  • 6
    • 79955615654 scopus 로고    scopus 로고
    • Ferreting out stem cells from their niches
    • Fuchs, E., Horsley, V., 2011. Ferreting out stem cells from their niches. Nat. Cell Biol. 13 (5), 513-518.
    • (2011) Nat. Cell Biol. , vol.13 , Issue.5 , pp. 513-518
    • Fuchs, E.1    Horsley, V.2
  • 7
    • 1642264093 scopus 로고    scopus 로고
    • The role of oxidative stress in the pathogenesis of multiple sclerosis: the need for effective antioxidant therapy
    • Gilgun-Sherki, Y., Melamed, E., et al., 2004. The role of oxidative stress in the pathogenesis of multiple sclerosis: the need for effective antioxidant therapy. J. Neurol. 251 (3), 261-268.
    • (2004) J. Neurol. , vol.251 , Issue.3 , pp. 261-268
    • Gilgun-Sherki, Y.1    Melamed, E.2
  • 8
    • 79956202078 scopus 로고    scopus 로고
    • Effect of dental materials calcium hydroxidecontaining cement, mineral trioxide aggregate, and enamel matrix derivative on proliferation and differentiation of human tooth germ stem cells
    • Guven, E.P., Yalvaç, M.E., et al., 2011. Effect of dental materials calcium hydroxidecontaining cement, mineral trioxide aggregate, and enamel matrix derivative on proliferation and differentiation of human tooth germ stem cells. J. Endod. 37 (5), 650-656.
    • (2011) J. Endod. , vol.37 , Issue.5 , pp. 650-656
    • Guven, E.P.1    Yalvaç, M.E.2
  • 9
    • 0034658541 scopus 로고    scopus 로고
    • Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors
    • Hirano, T., Ishihara, K., et al., 2000. Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors. Oncogene 19 (21), 2548-2556.
    • (2000) Oncogene , vol.19 , Issue.21 , pp. 2548-2556
    • Hirano, T.1    Ishihara, K.2
  • 10
    • 70349510607 scopus 로고    scopus 로고
    • Mesenchymal stem cells derived from dental tissues vs. those from other sources: their biology and role in regenerative medicine
    • Huang, G.T., Gronthos, S., et al., 2009. Mesenchymal stem cells derived from dental tissues vs. those from other sources: their biology and role in regenerative medicine. J. Dent. Res. 88 (9), 792-806.
    • (2009) J. Dent. Res. , vol.88 , Issue.9 , pp. 792-806
    • Huang, G.T.1    Gronthos, S.2
  • 11
    • 45449092100 scopus 로고    scopus 로고
    • Pramipexole has astrocyte-mediated neuroprotective effects against lactacystin toxicity
    • Imamura, K., Takeshima, T., et al., 2008. Pramipexole has astrocyte-mediated neuroprotective effects against lactacystin toxicity. Neurosci. Lett. 440 (2), 97-102.
    • (2008) Neurosci. Lett. , vol.440 , Issue.2 , pp. 97-102
    • Imamura, K.1    Takeshima, T.2
  • 12
    • 68949209290 scopus 로고    scopus 로고
    • Neuroprotective mesenchymal stem cells are endowed with a potent antioxidant effect in vivo
    • Lanza, C., Morando, S., et al., 2009. Neuroprotective mesenchymal stem cells are endowed with a potent antioxidant effect in vivo. J. Neurochem. 110 (5), 1674-1684.
    • (2009) J. Neurochem. , vol.110 , Issue.5 , pp. 1674-1684
    • Lanza, C.1    Morando, S.2
  • 13
    • 77956638921 scopus 로고    scopus 로고
    • A long-term follow-up study of intravenous autologous mesenchymal stem cell transplantation in patients with ischemic stroke
    • Lee, J.S., Hong, J.M., et al., 2010. A long-term follow-up study of intravenous autologous mesenchymal stem cell transplantation in patients with ischemic stroke. Stem Cells 28 (6), 1099-1106.
    • (2010) Stem Cells , vol.28 , Issue.6 , pp. 1099-1106
    • Lee, J.S.1    Hong, J.M.2
  • 14
    • 33747344967 scopus 로고    scopus 로고
    • Transforming growth factor-a: a major human serum factor that promotes human keratinocyte migration
    • Li, Y., Fan, J., et al., 2006. Transforming growth factor-a: a major human serum factor that promotes human keratinocyte migration. J. Invest. Dermatol. 126 (9), 2096-2105.
    • (2006) J. Invest. Dermatol. , vol.126 , Issue.9 , pp. 2096-2105
    • Li, Y.1    Fan, J.2
  • 15
    • 77953861126 scopus 로고    scopus 로고
    • Paracrine factors from human placental multipotent mesenchymal stromal cells protect endothelium from oxidative injury via STAT3 and manganese superoxide dismutase activation
    • Liu, S.H., Huang, J.P., et al., 2010. Paracrine factors from human placental multipotent mesenchymal stromal cells protect endothelium from oxidative injury via STAT3 and manganese superoxide dismutase activation. Biol. Reprod. 82 (5), 905-913.
    • (2010) Biol. Reprod. , vol.82 , Issue.5 , pp. 905-913
    • Liu, S.H.1    Huang, J.P.2
  • 16
    • 34447104560 scopus 로고    scopus 로고
    • Interleukin-6 (IL-6) modulates migration and matrix metalloproteinase function in dermal fibroblasts from IL-6 KO mice
    • Luckett, L.R., Gallucci, R.M., 2007. Interleukin-6 (IL-6) modulates migration and matrix metalloproteinase function in dermal fibroblasts from IL-6 KO mice. Br. J. Dermatol. 156 (6), 1163-1171.
    • (2007) Br. J. Dermatol. , vol.156 , Issue.6 , pp. 1163-1171
    • Luckett, L.R.1    Gallucci, R.M.2
  • 17
    • 0037687418 scopus 로고    scopus 로고
    • SHED: stem cells from human exfoliated deciduous teeth
    • Miura, M., Gronthos, S., et al., 2003. SHED: stem cells from human exfoliated deciduous teeth. Proc. Natl. Acad. Sci. USA 100 (10), 5807-5812.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , Issue.10 , pp. 5807-5812
    • Miura, M.1    Gronthos, S.2
  • 18
    • 0035062021 scopus 로고    scopus 로고
    • Interleukin-10 and the interleukin-10 receptor
    • Moore, K.W., de Waal Malefyt, R., et al., 2001. Interleukin-10 and the interleukin-10 receptor. Annu. Rev. Immunol. 19, 683-765.
    • (2001) Annu. Rev. Immunol. , vol.19 , pp. 683-765
    • Moore, K.W.1    de Waal Malefyt, R.2
  • 19
    • 0035477752 scopus 로고    scopus 로고
    • Dental pulp cells produce neurotrophic factors, interact with trigeminal neurons in vitro, and rescue motoneurons after spinal cord injury
    • Nosrat, I.V., Widenfalk, J., et al., 2001. Dental pulp cells produce neurotrophic factors, interact with trigeminal neurons in vitro, and rescue motoneurons after spinal cord injury. Dev. Biol. 238 (1), 120-132.
    • (2001) Dev. Biol. , vol.238 , Issue.1 , pp. 120-132
    • Nosrat, I.V.1    Widenfalk, J.2
  • 20
    • 2442430527 scopus 로고    scopus 로고
    • Dental pulp cells provide neurotrophic support for dopaminergic neurons and differentiate into neurons in vitro; implications for tissue engineering and repair in the nervous system
    • Nosrat, I.V., Smith, C.A., et al., 2004. Dental pulp cells provide neurotrophic support for dopaminergic neurons and differentiate into neurons in vitro; implications for tissue engineering and repair in the nervous system. Eur. J. Neurosci. 19 (9), 2388-2398.
    • (2004) Eur. J. Neurosci. , vol.19 , Issue.9 , pp. 2388-2398
    • Nosrat, I.V.1    Smith, C.A.2
  • 21
    • 0030812891 scopus 로고    scopus 로고
    • Transforming growth factor-b protects human hNT cells from degeneration induced by b-amyloid peptide: involvement of the TGF-b type II receptor
    • Ren, R.F., Hawver, D.B., et al., 1997. Transforming growth factor-b protects human hNT cells from degeneration induced by b-amyloid peptide: involvement of the TGF-b type II receptor. Brain Res. Mol. Brain Res. 48 (2), 315-322.
    • (1997) Brain Res. Mol. Brain Res. , vol.48 , Issue.2 , pp. 315-322
    • Ren, R.F.1    Hawver, D.B.2
  • 22
    • 77957287327 scopus 로고    scopus 로고
    • Interaction and self-organization of human mesenchymal stem cells and neuro-blastoma SH-SY5Y cells under co-culture conditions: a novel system for modeling cancer cell micro-environment
    • Rizvanov, A.A., Yalvaç, M.E., et al., 2010. Interaction and self-organization of human mesenchymal stem cells and neuro-blastoma SH-SY5Y cells under co-culture conditions: a novel system for modeling cancer cell micro-environment. Eur. J. Pharm. Biopharm. 76 (2), 253-259.
    • (2010) Eur. J. Pharm. Biopharm. , vol.76 , Issue.2 , pp. 253-259
    • Rizvanov, A.A.1    Yalvaç, M.E.2
  • 23
    • 78751532790 scopus 로고    scopus 로고
    • Genetically modified human umbilical cord blood cells expressing vascular endothelial growth factor and fibroblast growth factor 2 differentiate into glial cells after transplantation into amyotrophic lateral sclerosis transgenic mice
    • Rizvanov, A.A., Guseva, D.S., et al., 2011. Genetically modified human umbilical cord blood cells expressing vascular endothelial growth factor and fibroblast growth factor 2 differentiate into glial cells after transplantation into amyotrophic lateral sclerosis transgenic mice. Exp. Biol. Med. (Maywood) 236 (1), 91-98.
    • (2011) Exp. Biol. Med. (Maywood) , vol.236 , Issue.1 , pp. 91-98
    • Rizvanov, A.A.1    Guseva, D.S.2
  • 24
    • 33847668419 scopus 로고    scopus 로고
    • Increased Bax/Bcl-2 ratio up-regulates caspase-3 and increases apoptosis in the thymus of patients with myasthenia gravis
    • Salakou, S., Kardamakis, D., et al., 2007. Increased Bax/Bcl-2 ratio up-regulates caspase-3 and increases apoptosis in the thymus of patients with myasthenia gravis. In Vivo 21 (1), 123-132.
    • (2007) In Vivo , vol.21 , Issue.1 , pp. 123-132
    • Salakou, S.1    Kardamakis, D.2
  • 25
    • 84870877091 scopus 로고    scopus 로고
    • Isolation and characterization of dental pulp stem cells from a patient with Papillon-Lefevre syndrome
    • Tasli, P.N., Tapsin, S., et al., 2013. Isolation and characterization of dental pulp stem cells from a patient with Papillon-Lefevre syndrome. J. Endod. 39 (1), 31-38.
    • (2013) J. Endod. , vol.39 , Issue.1 , pp. 31-38
    • Tasli, P.N.1    Tapsin, S.2
  • 26
    • 77950628997 scopus 로고    scopus 로고
    • Mesenchymal stem cell-conditioned medium accelerates skin wound healing: an in vitro study of fibroblast and keratinocyte scratch assays
    • Walter, M.N., Wright, K.T., et al., 2010. Mesenchymal stem cell-conditioned medium accelerates skin wound healing: an in vitro study of fibroblast and keratinocyte scratch assays. Exp. Cell Res. 316 (7), 1271-1281.
    • (2010) Exp. Cell Res. , vol.316 , Issue.7 , pp. 1271-1281
    • Walter, M.N.1    Wright, K.T.2
  • 27
    • 0036323779 scopus 로고    scopus 로고
    • Ischemic cerebral tissue and MCP-1 enhance rat bone marrow stromal cell migration in interface culture
    • Wang, L., Li, Y., et al., 2002. Ischemic cerebral tissue and MCP-1 enhance rat bone marrow stromal cell migration in interface culture. Exp. Hematol. 30 (7), 831-836.
    • (2002) Exp. Hematol. , vol.30 , Issue.7 , pp. 831-836
    • Wang, L.1    Li, Y.2
  • 28
    • 0034712109 scopus 로고    scopus 로고
    • Out of Eden: stem cells and their niches
    • Watt, F.M., Hogan, B.L., 2000. Out of Eden: stem cells and their niches. Science 287 (5457), 1427-1430.
    • (2000) Science , vol.287 , Issue.5457 , pp. 1427-1430
    • Watt, F.M.1    Hogan, B.L.2
  • 29
    • 65949098670 scopus 로고    scopus 로고
    • Comparison and optimisation of transfection of human dental follicle cells, a novel source of stem cells, with different chemical methods and electro-poration
    • Yalvaç, M.E., Ramazanoglu, M., et al., 2009. Comparison and optimisation of transfection of human dental follicle cells, a novel source of stem cells, with different chemical methods and electro-poration. Neurochem. Res. 34 (7), 1272-1277.
    • (2009) Neurochem. Res. , vol.34 , Issue.7 , pp. 1272-1277
    • Yalvaç, M.E.1    Ramazanoglu, M.2
  • 30
    • 70649104690 scopus 로고    scopus 로고
    • Potential role of dental stem cells in the cellular therapy of cerebral ischemia
    • Yalvaç, M.E., Rizvanov, A.A., et al., 2009. Potential role of dental stem cells in the cellular therapy of cerebral ischemia. Curr. Pharm. Des. 15 (33), 3908-3916.
    • (2009) Curr. Pharm. Des. , vol.15 , Issue.33 , pp. 3908-3916
    • Yalvaç, M.E.1    Rizvanov, A.A.2
  • 31
    • 77950020375 scopus 로고    scopus 로고
    • Isolation and characterization of stem cells derived from human third molar tooth germs of young adults: implications in neo-vascularization, osteo-, adipo-and neurogenesis
    • Yalvaç, M.E., Ramazanoglu, M., et al., 2010a. Isolation and characterization of stem cells derived from human third molar tooth germs of young adults: implications in neo-vascularization, osteo-, adipo-and neurogenesis. Pharmacogenomics J. 10 (2), 105-113.
    • (2010) Pharmacogenomics J. , vol.10 , Issue.2 , pp. 105-113
    • Yalvaç, M.E.1    Ramazanoglu, M.2
  • 32
    • 77949677147 scopus 로고    scopus 로고
    • Human tooth germ stem cells preserve neuro-protective effects after long-term cryo-preservation
    • Yalvaç, M.E., Ramazanoglu, M., et al., 2010b. Human tooth germ stem cells preserve neuro-protective effects after long-term cryo-preservation. Curr. Neurovasc. Res. 7 (1), 49-58.
    • (2010) Curr. Neurovasc. Res. , vol.7 , Issue.1 , pp. 49-58
    • Yalvaç, M.E.1    Ramazanoglu, M.2
  • 33
    • 80755133427 scopus 로고    scopus 로고
    • Differentiation and neuro-protective properties of immortalized human tooth germ stem cells
    • Yalvaç, M.E., Yilmaz, A., et al., 2011. Differentiation and neuro-protective properties of immortalized human tooth germ stem cells. Neurochem. Res. 36 (12), 2227-2235.
    • (2011) Neurochem. Res. , vol.36 , Issue.12 , pp. 2227-2235
    • Yalvaç, M.E.1    Yilmaz, A.2
  • 34
    • 33846935035 scopus 로고    scopus 로고
    • Comparison of rat mesenchymal stem cells derived from bone marrow, synovium, periosteum, adipose tissue, and muscle
    • Yoshimura, H., Muneta, T., et al., 2007. Comparison of rat mesenchymal stem cells derived from bone marrow, synovium, periosteum, adipose tissue, and muscle. Cell Tissue Res. 327 (3), 449-462.
    • (2007) Cell Tissue Res. , vol.327 , Issue.3 , pp. 449-462
    • Yoshimura, H.1    Muneta, T.2
  • 35
    • 43549106847 scopus 로고    scopus 로고
    • A combined procedure to deliver autologous mesenchymal stromal cells to patients with traumatic brain injury
    • Zhang, Z.X., Guan, L.X., et al., 2008. A combined procedure to deliver autologous mesenchymal stromal cells to patients with traumatic brain injury. Cytotherapy 10 (2), 134-139.
    • (2008) Cytotherapy , vol.10 , Issue.2 , pp. 134-139
    • Zhang, Z.X.1    Guan, L.X.2
  • 36
    • 0034747307 scopus 로고    scopus 로고
    • TGF-b1 inhibits caspase-3 activation and neuronal apoptosis in rat hippocampal cultures
    • Zhu, Y., Ahlemeyer, B., et al., 2001. TGF-b1 inhibits caspase-3 activation and neuronal apoptosis in rat hippocampal cultures. Neurochem. Int. 38 (3), 227-235.
    • (2001) Neurochem. Int. , vol.38 , Issue.3 , pp. 227-235
    • Zhu, Y.1    Ahlemeyer, B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.