-
2
-
-
84855792427
-
Cancer statistics, 2012
-
Siegel R, Naishadham D and Jemal A: Cancer statistics, 2012. CA Cancer J Clin 62 (1): 10-29, 2012.
-
(2012)
CA Cancer J Clin
, vol.62
, Issue.1
, pp. 10-29
-
-
Siegel, R.1
Naishadham, D.2
Jemal, A.3
-
3
-
-
79958043675
-
-
National Cancer Institute. Bethesda, MD, based on November 2012 SEER data submission, posted to the SEER web site, April
-
Howlader N, Noone AM, Krapcho M, Garshell J, Neyman N, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z, Cho H, Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds.). SEER Cancer Statistics Review, 1975-2010, National Cancer Institute. Bethesda, MD, based on November 2012 SEER data submission, posted to the SEER web site, April 2013.
-
(2013)
SEER Cancer Statistics Review, 1975-2010
-
-
Howlader, N.1
Noone, A.M.2
Krapcho, M.3
Garshell, J.4
Neyman, N.5
Altekruse, S.F.6
Kosary, C.L.7
Yu, M.8
Ruhl, J.9
Tatalovich, Z.10
Cho, H.11
Mariotto, A.12
Lewis, D.R.13
Chen, H.S.14
Feuer, E.J.15
Cronin, K.A.16
-
4
-
-
33746808398
-
Wnt/beta-catenin signaling in development and disease
-
Clevers H: Wnt/beta-catenin signaling in development and disease. Cell 127: 469-480, 2006.
-
(2006)
Cell
, vol.127
, pp. 469-480
-
-
Clevers, H.1
-
6
-
-
19644373254
-
Wnt signaling in disease and in development
-
Nusse R. Wnt signaling in disease and in development. Cell Res 15: 28-32, 2005.
-
(2005)
Cell Res
, vol.15
, pp. 28-32
-
-
Nusse, R.1
-
7
-
-
0033895709
-
Wnt signaling and cancer
-
Polakis P: Wnt signaling and cancer. Genes Dev 14: 1837-1851, 2000
-
(2000)
Genes Dev
, vol.14
, pp. 1837-1851
-
-
Polakis, P.1
-
8
-
-
33744791463
-
Wnt signaling: Is the party in the nucleus?
-
Willert K and Jones KA: Wnt signaling: is the party in the nucleus? Genes Dev 20: 1394-1404, 2006.
-
(2006)
Genes Dev
, vol.20
, pp. 1394-1404
-
-
Willert, K.1
Jones, K.A.2
-
9
-
-
0030978351
-
Betacatenin is a target for the ubiquitin-proteasome pathway
-
Aberle H, Bauer A, Stappert J, Kispert A and Kemler R: betacatenin is a target for the ubiquitin-proteasome pathway. EMBO J 16(13): 3797-3804, 1997.
-
(1997)
EMBO J
, vol.16
, Issue.13
, pp. 3797-3804
-
-
Aberle, H.1
Bauer, A.2
Stappert, J.3
Kispert, A.4
Kemler, R.5
-
10
-
-
70350492327
-
Aurora kinase A is a target of Wnt/beta-catenin involved in multiple myeloma disease progression
-
Dutta-Simmons J, Zhang Y, Gorgun G, Gatt M, Mani M, Hideshima T, Takada K, Carlson NE, Carrasco DE, Tai YT, Raje N, Letai AG, Anderson KC and Carrasco DR: Aurora kinase A is a target of Wnt/beta-catenin involved in multiple myeloma disease progression. Blood 114: 2699-708, 2009.
-
(2009)
Blood
, vol.114
, pp. 2699-2708
-
-
Dutta-Simmons, J.1
Zhang, Y.2
Gorgun, G.3
Gatt, M.4
Mani, M.5
Hideshima, T.6
Takada, K.7
Carlson, N.E.8
Carrasco, D.E.9
Tai, Y.T.10
Raje, N.11
Letai, A.G.12
Anderson, K.C.13
Carrasco, D.R.14
-
12
-
-
34250678970
-
Targeting the beta-catenin/TCF transcriptional complex in the treatment of multiple myeloma
-
Sukhdeo K, Mani M, Zhang Y, Dutta J, Yasui H, Rooney MD, Carrasco DE, Zheng M, He H, Tai YT, Mitsiades C, Anderson KC and Carrasco DR: Targeting the beta-catenin/TCF transcriptional complex in the treatment of multiple myeloma. Proc Natl Acad Sci USA 104: 7516-7521, 2007.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 7516-7521
-
-
Sukhdeo, K.1
Mani, M.2
Zhang, Y.3
Dutta, J.4
Yasui, H.5
Rooney, M.D.6
Carrasco, D.E.7
Zheng, M.8
He, H.9
Tai, Y.T.10
Mitsiades, C.11
Anderson, K.C.12
Carrasco, D.R.13
-
13
-
-
11144355390
-
Illegitimate WNT signaling promotes proliferation of multiple myeloma cells
-
Derksen PW, Tjin E, Meijer HP, Klok MD, MacGillavry HD, van Oers MH, Lokhorst HM, Bloem AC, Clevers H, Nusse R, van der Neut R, Spaargaren M and Pals ST: Illegitimate WNT signaling promotes proliferation of multiple myeloma cells. Proc Natl Acad Sci USA 101: 6122-6127, 2004
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 6122-6127
-
-
Derksen, P.W.1
Tjin, E.2
Meijer, H.P.3
Klok, M.D.4
MacGillavry, H.D.5
Van Oers, M.H.6
Lokhorst, H.M.7
Bloem, A.C.8
Clevers, H.9
Nusse, R.10
Van Der Neut, R.11
Spaargaren, M.12
Pals, S.T.13
-
14
-
-
79951494668
-
Initial genome sequencing and analysis of multiple myeloma
-
Chapman MA, Lawrence MS, Keats JJ, Cibulskis K, Sougnez C, Schinzel AC, Harview CL, Brunet JP, Ahmann GJ, Adli M, Anderson KC, Ardlie KG, Auclair D, Baker A, Bergsagel PL, Bernstein BE, Drier Y, Fonseca R, Gabriel SB, Hofmeister CC, Jagannath S, Jakubowiak AJ, Krishnan A, Levy J, Liefeld T, Lonial S, Mahan S, Mfuko B, Monti S, Perkins LM, Onofrio R, Pugh TJ, Rajkumar SV, Ramos AH, Siegel DS, Sivachenko A, Stewart AK, Trudel S, Vij R, Voet D, Winckler W, Zimmerman T, Carpten J, Trent J, Hahn WC, Garraway LA, Meyerson M, Lander ES, Getz G and Golub TR: Initial genome sequencing and analysis of multiple myeloma. Nature 471: 467-472, 2011.
-
(2011)
Nature
, vol.471
, pp. 467-472
-
-
Chapman, M.A.1
Lawrence, M.S.2
Keats, J.J.3
Cibulskis, K.4
Sougnez, C.5
Schinzel, A.C.6
Harview, C.L.7
Brunet, J.P.8
Ahmann, G.J.9
Adli, M.10
Anderson, K.C.11
Ardlie, K.G.12
Auclair, D.13
Baker, A.14
Bergsagel, P.L.15
Bernstein, B.E.16
Drier, Y.17
Fonseca, R.18
Gabriel, S.B.19
Hofmeister, C.C.20
Jagannath, S.21
Jakubowiak, A.J.22
Krishnan, A.23
Levy, J.24
Liefeld, T.25
Lonial, S.26
Mahan, S.27
Mfuko, B.28
Monti, S.29
Perkins, L.M.30
Onofrio, R.31
Pugh, T.J.32
Rajkumar, S.V.33
Ramos, A.H.34
Siegel, D.S.35
Sivachenko, A.36
Stewart, A.K.37
Trudel, S.38
Vij, R.39
Voet, D.40
Winckler, W.41
Zimmerman, T.42
Carpten, J.43
Trent, J.44
Hahn, W.C.45
Garraway, L.A.46
Meyerson, M.47
Lander, E.S.48
Getz, G.49
Golub, T.R.50
more..
-
15
-
-
65249127502
-
{beta}-Catenin small interfering RNA successfully suppressed progression of multiple myeloma in a mouse model
-
Ashihara E, Kawata E, Nakagawa Y, Shimazaski C, Kuroda J, Taniguchi K, Uchiyama H, Tanaka R, Yokota A, Takeuchi M, Kamitsuji Y, Inaba T, Taniwaki M, Kimura S and Maekawa T: {beta}-Catenin small interfering RNA successfully suppressed progression of multiple myeloma in a mouse model. Clin Cancer Res 15: 2731-2738, 2009.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 2731-2738
-
-
Ashihara, E.1
Kawata, E.2
Nakagawa, Y.3
Shimazaski, C.4
Kuroda, J.5
Taniguchi, K.6
Uchiyama, H.7
Tanaka, R.8
Yokota, A.9
Takeuchi, M.10
Kamitsuji, Y.11
Inaba, T.12
Taniwaki, M.13
Kimura, S.14
Maekawa, T.15
-
16
-
-
0037236924
-
Inhibition of constitutive STAT3 activity sensitizes resistant non-Hodgkin's lymphoma and multiple myeloma to chemotherapeutic drug-mediated apoptosis
-
Alas S and Bonavida B: Inhibition of constitutive STAT3 activity sensitizes resistant non-Hodgkin's lymphoma and multiple myeloma to chemotherapeutic drug-mediated apoptosis. Clin Cancer Res 9(1): 316-326, 2003.
-
(2003)
Clin Cancer Res
, vol.9
, Issue.1
, pp. 316-326
-
-
Alas, S.1
Bonavida, B.2
-
17
-
-
84862786059
-
In vivo efficacy of the diuretic agent ethacrynic acid against multiple myeloma
-
Kim Y, Gast SM, Endo T, Lu D, Carson D and Schmidt-Wolf IG: In vivo efficacy of the diuretic agent ethacrynic acid against multiple myeloma. Leuk Res 36(5): 598-600, 2012.
-
(2012)
Leuk Res
, vol.36
, Issue.5
, pp. 598-600
-
-
Kim, Y.1
Gast, S.M.2
Endo, T.3
Lu, D.4
Carson, D.5
Schmidt-Wolf, I.G.6
-
18
-
-
80755142841
-
Targeting the Wnt/beta-catenin pathway with the antifungal agent ciclopirox olamine in a murine myeloma model
-
Kim Y, Schmidt M, Endo T, Lu D, Carson D and Schmidt-Wolf IG: Targeting the Wnt/beta-catenin pathway with the antifungal agent ciclopirox olamine in a murine myeloma model. In Vivo 25(6): 887-893, 2011.
-
(2011)
In Vivo
, vol.25
, Issue.6
, pp. 887-893
-
-
Kim, Y.1
Schmidt, M.2
Endo, T.3
Lu, D.4
Carson, D.5
Schmidt-Wolf, I.G.6
-
19
-
-
84860537254
-
Bone marrow stromal cells create a permissive microenvironment for myeloma development: A new stromal role for Wnt inhibitor Dkk1
-
Fowler JA, Mundy GR, Lwin ST and Edwards CM: Bone marrow stromal cells create a permissive microenvironment for myeloma development: a new stromal role for Wnt inhibitor Dkk1. Cancer Res 72(9): 2183-2189, 2012.
-
(2012)
Cancer Res
, vol.72
, Issue.9
, pp. 2183-2189
-
-
Fowler, J.A.1
Mundy, G.R.2
Lwin, S.T.3
Edwards, C.M.4
-
20
-
-
84857155905
-
Transcriptional silencing of the Wnt-antagonist DKK1 by promoter methylation is associated with enhanced Wnt signaling in advanced multiple myeloma
-
Kocemba KA, Groen RW, van Andel H, Kersten MJ, Mahtouk K, Spaargaren M and Pals ST: Transcriptional silencing of the Wnt-antagonist DKK1 by promoter methylation is associated with enhanced Wnt signaling in advanced multiple myeloma. PLoS One 7(2): e30359, 2012.
-
(2012)
PLoS One
, vol.7
, Issue.2
-
-
Kocemba, K.A.1
Groen, R.W.2
Van Andel, H.3
Kersten, M.J.4
Mahtouk, K.5
Spaargaren, M.6
Pals, S.T.7
-
21
-
-
34547106018
-
Understanding multiple myeloma pathogenesis in the bone marrow to identify new therapeutic targets
-
Hideshima T, Mitsiades C, Tonon G, Richardson PG and Anderson KC: Understanding multiple myeloma pathogenesis in the bone marrow to identify new therapeutic targets. Nat Rev Cancer 7: 585-598, 2007.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 585-598
-
-
Hideshima, T.1
Mitsiades, C.2
Tonon, G.3
Richardson, P.G.4
Anderson, K.C.5
-
22
-
-
79956359593
-
Increased in vivo efficacy of lenalidomide and thalidomide by addition of ethacrynic acid
-
Schmidt M, Kim Y, Gast SM, Endo T, Lu D, Carson D and Schmidt-Wolf IG: Increased in vivo efficacy of lenalidomide and thalidomide by addition of ethacrynic acid. In Vivo 25(3): 325-333, 2011.
-
(2011)
In Vivo
, vol.25
, Issue.3
, pp. 325-333
-
-
Schmidt, M.1
Kim, Y.2
Gast, S.M.3
Endo, T.4
Lu, D.5
Carson, D.6
Schmidt-Wolf, I.G.7
-
23
-
-
77954069621
-
Ethacrynic acid exhibits selective toxicity to chronic lymphocytic leukemia cells by inhibition of the Wnt/beta-catenin pathway
-
Lu D, Liu JX, Endo T, Zhou H, Yao S, Willert K, Schmidt-Wolf IG, Kipps TJ and Carson DA: Ethacrynic acid exhibits selective toxicity to chronic lymphocytic leukemia cells by inhibition of the Wnt/beta-catenin pathway. PLoS One 4 (12): e8294, 2009.
-
(2009)
PLoS One
, vol.4
, Issue.12
-
-
Lu, D.1
Liu, J.X.2
Endo, T.3
Zhou, H.4
Yao, S.5
Willert, K.6
Schmidt-Wolf, I.G.7
Kipps, T.J.8
Carson, D.A.9
-
24
-
-
3142665469
-
TNF activates Syk protein tyrosine kinase leading to TNF-induced MAPK activation, NF-κB activation, and apoptosis
-
Takada Y and Aggarwal BB: TNF activates Syk protein tyrosine kinase leading to TNF-induced MAPK activation, NF-κB activation, and apoptosis. Journal of Immunology 173(2): 1066-1077, 2004.
-
(2004)
Journal of Immunology
, vol.173
, Issue.2
, pp. 1066-1077
-
-
Takada, Y.1
Aggarwal, B.B.2
-
25
-
-
70350507937
-
The grape component piceatannol induces apoptosis in du145 human prostate cancer cells via the activation of extrinsic and intrinsic pathways
-
Kim EJ, Park H, Park SY, Jun JG and Park JHY: The grape component piceatannol induces apoptosis in du145 human prostate cancer cells via the activation of extrinsic and intrinsic pathways. Journal of Medicinal Food 12(5): 943-951, 2009.
-
(2009)
Journal of Medicinal Food
, vol.12
, Issue.5
, pp. 943-951
-
-
Kim, E.J.1
Park, H.2
Park, S.Y.3
Jun, J.G.4
Park, J.H.Y.5
-
26
-
-
84887967828
-
AKT/mTOR as novel targets of polyphenol piceatannol possibly contributing to inhibition of proliferation of cultured prostate cancer cells
-
Hsieh TC, Lin CY, Lin HY and Wu JM: AKT/mTOR as novel targets of polyphenol piceatannol possibly contributing to inhibition of proliferation of cultured prostate cancer cells. ISRN Urology 2012: 272697, 2012.
-
(2012)
ISRN Urology
, vol.2012
, pp. 272697
-
-
Hsieh, T.C.1
Lin, C.Y.2
Lin, H.Y.3
Wu, J.M.4
-
27
-
-
84860334952
-
Piceatannol suppresses breast cancer cell invasion through the inhibition of MMP-9: Involvement of PI3K/AKT and NF-kappaB pathways
-
Ko HS, Lee HJ, Kim SH and Lee EO: Piceatannol suppresses breast cancer cell invasion through the inhibition of MMP-9: involvement of PI3K/AKT and NF-kappaB pathways. Journal of Agricultural and Food Chemistry 60: 4083-4089, 2012.
-
(2012)
Journal of Agricultural and Food Chemistry
, vol.60
, pp. 4083-4089
-
-
Ko, H.S.1
Lee, H.J.2
Kim, S.H.3
Lee, E.O.4
-
28
-
-
0036173620
-
Piceatannol, a natural analog of resveratrol, inhibits progression through the s phase of the cell cycle in colorectal cancer cell lines
-
Wolter F, Clausnitzer A, Akoglu B, Stein J. Piceatannol, a natural analog of resveratrol, inhibits progression through the s phase of the cell cycle in colorectal cancer cell lines. Journal of Nutrition 132(2): 298-302, 2002.
-
(2002)
Journal of Nutrition
, vol.132
, Issue.2
, pp. 298-302
-
-
Wolter, F.1
Clausnitzer, A.2
Akoglu, B.3
Stein, J.4
-
29
-
-
84874233056
-
Fungicidal drugs induce a common oxidative-damage cellular death pathway
-
Belenky P, Camacho D and Collins JJ: Fungicidal drugs induce a common oxidative-damage cellular death pathway. Cell Rep 3(2): 350-358, 2013.
-
(2013)
Cell Rep
, vol.3
, Issue.2
, pp. 350-358
-
-
Belenky, P.1
Camacho, D.2
Collins, J.J.3
-
30
-
-
70449466605
-
Chelation of intracellular iron with the antifungal agent ciclopirox olamine induces cell death in leukemia and myeloma cells
-
Eberhard Y, McDermott SP, Wang X, Gronda M, Venugopal A, Wood TE, Hurren R, Datti A, Batey RA, Wrana J, Antholine WE, Dick JE, Schimmer AD. Chelation of intracellular iron with the antifungal agent ciclopirox olamine induces cell death in leukemia and myeloma cells. Blood 114(14): 3064-3073, 2009.
-
(2009)
Blood
, vol.114
, Issue.14
, pp. 3064-3073
-
-
Eberhard, Y.1
McDermott, S.P.2
Wang, X.3
Gronda, M.4
Venugopal, A.5
Wood, T.E.6
Hurren, R.7
Datti, A.8
Batey, R.A.9
Wrana, J.10
Antholine, W.E.11
Dick, J.E.12
Schimmer, A.D.13
-
31
-
-
78049512724
-
The antitumor activity of the fungicide ciclopirox
-
Zhou H, Shen T, Luo Y, Liu L, Chen W, Xu B, Han X, Pang J, Rivera CA and Huang S: The antitumor activity of the fungicide ciclopirox. Int J Cancer 127(10): 2467-2477, 2010.
-
(2010)
Int J Cancer
, vol.127
, Issue.10
, pp. 2467-2477
-
-
Zhou, H.1
Shen, T.2
Luo, Y.3
Liu, L.4
Chen, W.5
Xu, B.6
Han, X.7
Pang, J.8
Rivera, C.A.9
Huang, S.10
-
32
-
-
84255199531
-
Wnt inhibitor screen reveals iron dependence of β-catenin signaling in cancers
-
Song S, Christova T, Perusini S, Alizadeh S, Bao RY, Miller BW, Hurren R, Jitkova Y, Gronda M, Isaac M, Joseph B, Subramaniam R, Aman A, Chau A, Hogge DE, Weir SJ, Kasper J, Schimmer AD, Al-awar R, Wrana JL and Attisano L: Wnt inhibitor screen reveals iron dependence of β-catenin signaling in cancers. Cancer Res 71(24): 7628-7639, 2011.
-
(2011)
Cancer Res
, vol.71
, Issue.24
, pp. 7628-7639
-
-
Song, S.1
Christova, T.2
Perusini, S.3
Alizadeh, S.4
Bao, R.Y.5
Miller, B.W.6
Hurren, R.7
Jitkova, Y.8
Gronda, M.9
Isaac, M.10
Joseph, B.11
Subramaniam, R.12
Aman, A.13
Chau, A.14
Hogge, D.E.15
Weir, S.J.16
Kasper, J.17
Schimmer, A.D.18
Al-awar, R.19
Wrana, J.L.20
Attisano, L.21
more..
-
33
-
-
84855758079
-
Modulation of Wnt/β-catenin signaling and proliferation by a ferrous iron chelator with therapeutic efficacy in genetically engineered mouse models of cancer
-
Coombs GS, Schmitt AA, Canning CA, Alok A, Low IC, Banerjee N, Kaur S, Utomo V, Jones CM, Pervaiz S, Toone EJ and Virshup DM: Modulation of Wnt/β-catenin signaling and proliferation by a ferrous iron chelator with therapeutic efficacy in genetically engineered mouse models of cancer. Oncogene 31(2): 213-225, 2012.
-
(2012)
Oncogene
, vol.31
, Issue.2
, pp. 213-225
-
-
Coombs, G.S.1
Schmitt, A.A.2
Canning, C.A.3
Alok, A.4
Low, I.C.5
Banerjee, N.6
Kaur, S.7
Utomo, V.8
Jones, C.M.9
Pervaiz, S.10
Toone, E.J.11
Virshup, D.M.12
-
34
-
-
0023679751
-
Ethacrynic acid and piriprost as enhancers of cytotoxicity in drug resistant and sensitive cell lines
-
Tew KD, Bomber AM and Hoffman SJ: Ethacrynic acid and piriprost as enhancers of cytotoxicity in drug resistant and sensitive cell lines. Cancer Res 48(13): 3622-3625, 1988.
-
(1988)
Cancer Res
, vol.48
, Issue.13
, pp. 3622-3625
-
-
Tew, K.D.1
Bomber, A.M.2
Hoffman, S.J.3
-
35
-
-
0242609868
-
Characterization of cell death induced by ethacrynic acid in a human colon cancer cell line DLD-1 and suppression by N-acetyl-L-cysteine
-
Aizawa S, Ookawa K, Kudo T, Asano J, Hayakari M and Tsuchida S: Characterization of cell death induced by ethacrynic acid in a human colon cancer cell line DLD-1 and suppression by N-acetyl-L-cysteine. Cancer Sci 94 (10): 886-893, 2003.
-
(2003)
Cancer Sci
, vol.94
, Issue.10
, pp. 886-893
-
-
Aizawa, S.1
Ookawa, K.2
Kudo, T.3
Asano, J.4
Hayakari, M.5
Tsuchida, S.6
-
36
-
-
11444264654
-
Ethacrynic acid inhibits multiple steps in the NF-kappaB signaling pathway
-
Han Y, Englert JA, Delude RL and Fink MP: Ethacrynic acid inhibits multiple steps in the NF-kappaB signaling pathway. Shock 23(1): 45-53, 2005.
-
(2005)
Shock
, vol.23
, Issue.1
, pp. 45-53
-
-
Han, Y.1
Englert, J.A.2
Delude, R.L.3
Fink, M.P.4
|