Catechol-O-methyltransferase (COMT) genotype moderates the effects of childhood trauma on cognition and symptoms in schizophrenia

Journal of Psychiatric Research

Volumn 49, Issue 1, 2014, Pages 43-50

  Green, Melissa J ^a,b   Chia, T Yunn ^a,b   Cairns, Murray J ^b,c,d   Wu, Jingqin ^c,d   Tooney, Paul A ^b,c,d   Scott, Rodney J ^b,c,d,e   Carr, Vaughan J ^a,b  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b Schizophrenia Research Institute   (Australia)

^c UNIVERSITY OF NEWCASTLE   (Australia)

^d HUNTER MEDICAL RESEARCH INSTITUTE   (Australia)

^e JOHN HUNTER HOSPITAL   (Australia)

Author keywords

Catechol O methyltransferase (COMT); Childhood adversity; Cognition; Epigenetics; Genetics; Psychosis; Symptoms; Trauma

Indexed keywords

CATECHOL METHYLTRANSFERASE; DOPAMINE;

ADULT; AGED; ALLELE; ARTICLE; ATTENTION; CHILD NEGLECT; CHILDHOOD ADVERSITY QUESTIONNAIRE; CHILDHOOD INJURY; CLINICAL ASSESSMENT; COGNITION; CONTROLLED ORAL WORD ASSOCIATION TEST; CONTROLLED STUDY; DOPAMINE BRAIN LEVEL; EMOTIONAL ABUSE; EPIGENETICS; EXECUTIVE FUNCTION; FEMALE; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HOMOZYGOTE; HUMAN; LETTER NUMBER SEQUENCING TEST; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; NAMED INVENTORIES, QUESTIONNAIRES AND RATING SCALES; NEGATIVE SYNDROME; NEUROPSYCHOLOGICAL TEST; PHYSICAL ABUSE; POSITIVE SYNDROME; PREFRONTAL CORTEX; PRIORITY JOURNAL; QUESTIONNAIRE; REPEATABLE BATTERY FOR ASSESSMENT OF NEUROPSYCHOLOGICAL STATUS; SCHIZOPHRENIA; SEXUAL ABUSE; SHORT TERM MEMORY; SYMPTOM; WECHSLER TEST OF ADULT READING; YOUNG ADULT;

CATECHOL-O-METHYLTRANSFERASE (COMT); CHILDHOOD ADVERSITY; COGNITION; EPIGENETICS; GENETICS; PSYCHOSIS; SYMPTOMS; TRAUMA;

ADOLESCENT; ADULT; AGED; CATECHOL O-METHYLTRANSFERASE; CHILD ABUSE; COGNITION DISORDERS; FEMALE; GENOTYPE; HUMANS; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; POLYMORPHISM, SINGLE NUCLEOTIDE; PSYCHIATRIC STATUS RATING SCALES; QUESTIONNAIRES; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY; YOUNG ADULT;

EID: 84891148204     PISSN: 00223956     EISSN: 18791379     Source Type: Journal    
DOI: 10.1016/j.jpsychires.2013.10.018     Document Type: Article

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