Study on human promyelocytic leukemia HL-60 cells apoptosis induced by fucosterol

Bio-Medical Materials and Engineering

Volumn 24, Issue 1, 2014, Pages 845-851

  Ji, Yu Bin ^a   Ji, Chen Feng ^a   Yue, Lei ^b  

^a HARBIN UNIVERSITY OF COMMERCE   (China)

^b HARBIN INSTITUTE OF TECHNOLOGY   (China)

Author keywords

apoptosis; Fucosterol; Human promyelocytic leukemia; mechanism

Indexed keywords

ANTI-TUMOR ACTIVITIES; CASPASE-3 ACTIVATION; FUCOSTEROL; LASER SCANNING CONFOCAL MICROSCOPES; MITOCHONDRIAL MEMBRANE POTENTIAL; MOLECULAR MECHANISM; PROMYELOCYTIC LEUKEMIA; PROTEIN EXPRESSIONS;

BIOMEDICAL ENGINEERING; BIOTECHNOLOGY; CELL DEATH; DISEASES; MECHANISMS; MORPHOLOGY;

CALCIUM ION SENSORS;

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CASPASE 3; CASPASE 8; CASPASE 9; FAS ANTIGEN; FAS ASSOCIATED DEATH DOMAIN PROTEIN; FAS LIGAND; FUCOSTEROL; PROCASPASE 3; PROCASPASE 9;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; CANCER INHIBITION; CELL CYCLE ASSAY; CELL PROLIFERATION; CELL STRAIN HL 60; CELL STRUCTURE; CONFERENCE PAPER; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENZYME ACTIVITY; FLOW CYTOMETRY; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; PROTEIN EXPRESSION; WESTERN BLOTTING;

APOPTOSIS; FUCOSTEROL; HUMAN PROMYELOCYTIC LEUKEMIA; MECHANISM;

ANTIGENS, CD95; APOPTOSIS; CASPASE 3; CASPASE 8; CASPASE 9; CELL CYCLE; FAS LIGAND PROTEIN; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; GENE EXPRESSION REGULATION, LEUKEMIC; HL-60 CELLS; HUMANS; LEUKEMIA, PROMYELOCYTIC, ACUTE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; STIGMASTEROL;

EID: 84891126125     PISSN: 09592989     EISSN: None     Source Type: Journal    
DOI: 10.3233/BME-130876     Document Type: Conference Paper

References (9)

1. M. S. Yoo, J. S. Shin, H. E. Choi, et al. Fucosterol isolated from Undaria pinnatifida inhibits lipo-polysaccharide-induced production of nitric oxide and pro-inflammatory cytokines via the inactivation of nuclear factor-B and p38 mitogenactivated protein kinase in RAW264. 7 macrophages, Food Chem. 135 (2012), 967-975.
2. M. Khanavi, R. Gheidarloo, N. Sadati, et al. Cytotoxicity of fucosterol containing fraction of marine algae against breast and colon carcinoma cell line, Pharmacogn Mag. 8 (2012), 60-64.
3. L. J. Martin, The mitochondrial permeability transition pore: A molecular target for amyotrophic lateral sclerosis therapy, Biochim Biophys Acta. 1802 (2010); 186-197.
4. W. Lemeshko, Potential-dependent membrane permeabilization and mitochondrial aggregation caused by anticancer polyarginine-KLA peptides, Arch Biochem Biophys. 493 (2010), 213-220.
5. S. Luca, Opening the doors to cytochrome c: Changes in mitochondrial shape and apoptosis, Int J Biochem Cell Biol. 41 (2010), 1875-1883.
6. M. Villa-Morales and J. Fernandez-Piqueras, Targeting the Fas/FasL signaling pathway in cancer therapy, Expert Opin Ther Targets. 16 (2012), 85-101.
7. A. Robert, Y. Newman, P. Y. Alison, et al. Cardiac glycosides as novel cancer therapeutic agents, Mol. Interv. 8 (2008), 36-49.
8. Y. Zhao, X. Sui and H. Ren, From procaspase-8 to caspase-8: Revisiting structural functions of caspase-8, J Cell Physiol. 225 (2010), 316-320.
9. L. Galluzzi, O. Kepp and G. Kroemer, Caspase-3 and prostaglandins signal for tumor regrowth in cancer therapy, Oncogene. 31 (2012), 2805-2808.