메뉴 건너뛰기




Volumn 12, Issue 12, 2013, Pages 1371-1378

Nonsurgical treatment options for basal cell carcinoma - Focus on advanced disease

Author keywords

[No Author keywords available]

Indexed keywords

FLUOROURACIL; IMIQUIMOD; VISMODEGIB; ANTINEOPLASTIC AGENT;

EID: 84890960311     PISSN: 15459616     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (13)

References (110)
  • 1
    • 31644445651 scopus 로고    scopus 로고
    • Basal cell carcinoma: Biology, morphology and clinical implications
    • Crowson AN. Basal cell carcinoma: biology, morphology and clinical implications. Mod Pathol. 2006;19(Suppl 2):S127-S147.
    • (2006) Mod Pathol , vol.19 , Issue.SUPPL. 2
    • Crowson, A.N.1
  • 2
    • 84887916647 scopus 로고    scopus 로고
    • Clinical variants, stages, and management of basal cell carcinoma
    • Dourmishev LA, Rusinova D, Botev I. Clinical variants, stages, and management of basal cell carcinoma. Indian Dermatol Online J. 2013;4(1):12-17.
    • (2013) Indian Dermatol Online J , vol.4 , Issue.1 , pp. 12-17
    • Dourmishev, L.A.1    Rusinova, D.2    Botev, I.3
  • 3
    • 84856556569 scopus 로고    scopus 로고
    • Basal cell carcinoma - molecular - biology and potential new therapies
    • Kasper M, Jaks V, Hohl D, Toftgard R. Basal cell carcinoma - molecular - biology and potential new therapies. J Clin Invest. 2012;122(2):455-463.
    • (2012) J Clin Invest , vol.122 , Issue.2 , pp. 455-463
    • Kasper, M.1    Jaks, V.2    Hohl, D.3    Toftgard, R.4
  • 4
    • 4243795083 scopus 로고    scopus 로고
    • Available at Accessed June 19, 2013
    • National Cancer Institute at the National Institutes of Health. Skin cancer. Available at www.cancer.gov/cancertopics/types/skin. Accessed June 19, 2013.
    • Skin Cancer
  • 5
    • 84890905716 scopus 로고    scopus 로고
    • Ultra violet radiation and the INTERSUN Programme
    • Available at Accessed July 24, 2013
    • World Health Organization (WHO). Ultra violet radiation and the INTERSUN Programme. Skin cancer: How commo is skin cancer? Available at www. who.int/uv/faq/skincancer/en/index1.html#. Accessed July 24, 2013.
    • Skin Cancer: How Commo Is Skin Cancer?
  • 6
    • 84867805547 scopus 로고    scopus 로고
    • Epidemiology and economic burden of nonmelanoma skin cancer
    • Cakir BO, Adamson P, Cingi C. Epidemiology and economic burden of nonmelanoma skin cancer. Facial Plast Surg Clin North Am. 2012;20(4):419-422.
    • (2012) Facial Plast Surg Clin North Am , vol.20 , Issue.4 , pp. 419-422
    • Cakir, B.O.1    Adamson, P.2    Cingi, C.3
  • 8
    • 84877590369 scopus 로고    scopus 로고
    • Nonmelanoma skin cancer in young women
    • Wu TP, Stein JA. Nonmelanoma skin cancer in young women. J Drugs Dermatol. 2013;12(5):568-572.
    • (2013) J Drugs Dermatol , vol.12 , Issue.5 , pp. 568-572
    • Wu, T.P.1    Stein, J.A.2
  • 9
    • 0035667729 scopus 로고    scopus 로고
    • Cost of nonmelanoma skin cancer treatment in the United States
    • Chen JG, Fleischer AB Jr, Smith ED, et al. Cost of nonmelanoma skin cancer treatment in the United States. Dermatol Surg. 2001;27(12):1035-1038.
    • (2001) Dermatol Surg , vol.27 , Issue.12 , pp. 1035-1038
    • Chen, J.G.1    Fleischer Jr., A.B.2    Smith, E.D.3
  • 10
    • 84882251352 scopus 로고    scopus 로고
    • Actinic keratosis, basal cell carcinoma and squamous cell carcinoma
    • Bolognia JL, Jorizzo JL, Schaffer JV, eds. Third ed. New York: Elsevier Saunders
    • Soyer HP, Rigel DS, Wurm EMT. Actinic keratosis, basal cell carcinoma and squamous cell carcinoma. In: Bolognia JL, Jorizzo JL, Schaffer JV, eds. Dermatology. Vol 2. Third ed. New York: Elsevier Saunders; 2012:1773-1794.
    • (2012) Dermatology , vol.2 , pp. 1773-1794
    • Soyer, H.P.1    Rigel, D.S.2    Wurm, E.M.T.3
  • 11
    • 84885440830 scopus 로고    scopus 로고
    • Presentations and treatment of basal cell carcinoma: A review
    • Frankel A, Goldenberg G. Presentations and treatment of basal cell carcinoma: a review. Cutaneous Oncology Today. 2011 (October):5-9.
    • (2011) Cutaneous Oncology Today , Issue.OCTOBER , pp. 5-9
    • Frankel, A.1    Goldenberg, G.2
  • 12
    • 84876586267 scopus 로고    scopus 로고
    • Tumor recurrence 5 years after treatment of cutaneous basal cell carcinoma and squamous cell carcinoma
    • Chren MM, Linos E, Torres JS, Stuart SE, Parvataneni R, Boscardin WJ. Tumor recurrence 5 years after treatment of cutaneous basal cell carcinoma and squamous cell carcinoma. J Invest Dermatol. 2013;133(5):1188-1196.
    • (2013) J Invest Dermatol , vol.133 , Issue.5 , pp. 1188-1196
    • Chren, M.M.1    Linos, E.2    Torres, J.S.3    Stuart, S.E.4    Parvataneni, R.5    Boscardin, W.J.6
  • 13
    • 23744482479 scopus 로고    scopus 로고
    • Do basal cell carcinomas recur after complete conventional surgical excision?
    • Griffiths RW, Suvarna SK, Stone J. Do basal cell carcinomas recur after complete conventional surgical excision? Br J Plast Surg. 2005;58(6):795-805
    • (2005) Br J Plast Surg , vol.58 , Issue.6 , pp. 795-805
    • Griffiths, R.W.1    Suvarna, S.K.2    Stone, J.3
  • 16
  • 17
    • 33845235986 scopus 로고    scopus 로고
    • European Dermatology Forum Guideline C. Guidelines: The management of basal cell carcinoma
    • Sterry W, European Dermatology Forum Guideline C. Guidelines: the management of basal cell carcinoma. Eur J Dermatol. 2006;16(5):467-475.
    • (2006) Eur J Dermatol , vol.16 , Issue.5 , pp. 467-475
    • Sterry, W.1
  • 18
    • 35348882662 scopus 로고    scopus 로고
    • Factors affecting the recurrence rate of basal cell carcinoma
    • Bogelund FS, Philipsen PA, Gniadecki R. Factors affecting the recurrence rate of basal cell carcinoma. Acta Derm Venereol. 2007;87(4):330-334.
    • (2007) Acta Derm Venereol , vol.87 , Issue.4 , pp. 330-334
    • Bogelund, F.S.1    Philipsen, P.A.2    Gniadecki, R.3
  • 19
    • 77952836149 scopus 로고    scopus 로고
    • Clinical, histological and demographic predictors for recurrence and second primary tumours of head and neck basal cell carcinoma. A 1062 patient-cohort study from a tertiary cancer referral hospital
    • Kyrgidis A, Vahtsevanos K, Tzellos TG, et al. Clinical, histological and demographic predictors for recurrence and second primary tumours of head and neck basal cell carcinoma. A 1062 patient-cohort study from a tertiary cancer referral hospital. Eur J Dermatol. 2010;20(3):276-282.
    • (2010) Eur J Dermatol , vol.20 , Issue.3 , pp. 276-282
    • Kyrgidis, A.1    Vahtsevanos, K.2    Tzellos, T.G.3
  • 20
    • 84859571452 scopus 로고    scopus 로고
    • Evaluation of recurrence after photodynamic therapy with topical methylaminolaevulinate for 157 basal cell carcinomas in 90 patients
    • Lindberg-Larsen R, Solvsten H, Kragballe K. Evaluation of recurrence after photodynamic therapy with topical methylaminolaevulinate for 157 basal cell carcinomas in 90 patients. Acta Derm Venereol. 2012;92(2):144-147.
    • (2012) Acta Derm Venereol , vol.92 , Issue.2 , pp. 144-147
    • Lindberg-Larsen, R.1    Solvsten, H.2    Kragballe, K.3
  • 21
    • 76749096684 scopus 로고    scopus 로고
    • Non-melanoma skin cancer
    • Madan V, Lear JT, Szeimies RM. Non-melanoma skin cancer. Lancet.2010;375(9715):673-685.
    • (2010) Lancet , vol.375 , Issue.9715 , pp. 673-685
    • Madan, V.1    Lear, J.T.2    Szeimies, R.M.3
  • 23
    • 0029917721 scopus 로고    scopus 로고
    • Basal cell carcinoma. Identification and treatment of the highrisk patient
    • Randle HW. Basal cell carcinoma. Identification and treatment of the highrisk patient. Dermatol Surg. 1996;22(3):255-261.
    • (1996) Dermatol Surg , vol.22 , Issue.3 , pp. 255-261
    • Randle, H.W.1
  • 26
    • 0018936179 scopus 로고
    • Metastatic basal cell carcinoma: A clinicopathologic study of seventeen cases
    • Farmer ER, Helwig EB. Metastatic basal cell carcinoma: a clinicopathologic study of seventeen cases. Cancer. 1980;46(4):748-757.
    • (1980) Cancer , vol.46 , Issue.4 , pp. 748-757
    • Farmer, E.R.1    Helwig, E.B.2
  • 27
    • 79961002707 scopus 로고    scopus 로고
    • Systemic therapy for disseminated basal cell carcinoma: An uncommon manifestation of a common cancer
    • Ganti AK, Kessinger A. Systemic therapy for disseminated basal cell carcinoma: an uncommon manifestation of a common cancer. Cancer Treat Rev. 2011;37(6):440-443.
    • (2011) Cancer Treat Rev , vol.37 , Issue.6 , pp. 440-443
    • Ganti, A.K.1    Kessinger, A.2
  • 28
    • 0015712201 scopus 로고
    • Horrifying basal cell carcinoma: A study of 33 cases and a comparison with 435 non-horror cases and a report on four metastatic cases
    • Jackson R, Adams RH. Horrifying basal cell carcinoma: a study of 33 cases and a comparison with 435 non-horror cases and a report on four metastatic cases. J Surg Oncol. 1973;5(5):431-463.
    • (1973) J Surg Oncol , vol.5 , Issue.5 , pp. 431-463
    • Jackson, R.1    Adams, R.H.2
  • 30
    • 84881313469 scopus 로고    scopus 로고
    • Metastatic basal cell carcinoma: A case report and review of the literature
    • Vu A, Laub D Jr. Metastatic basal cell carcinoma: a case report and review of the literature. Eplasty. 2011;11:ic8.
    • (2011) Eplasty , vol.11
    • Vu, A.1    Laub Jr., D.2
  • 31
    • 84877863749 scopus 로고    scopus 로고
    • Update on metastatic basal cell carcinoma: A summary of published cases from 1981 through 2011
    • Wysong A, Aasi SZ, Tang JY. Update on metastatic basal cell carcinoma: a summary of published cases from 1981 through 2011. JAMA Dermatol. 2013;149(5):615-616.
    • (2013) JAMA Dermatol , vol.149 , Issue.5 , pp. 615-616
    • Wysong, A.1    Aasi, S.Z.2    Tang, J.Y.3
  • 32
    • 84867770220 scopus 로고    scopus 로고
    • Nonmelanoma skin cancer of the head and neck: Nonsurgical treatment
    • Ermertcan AT, Hellings PW, Cingi C. Nonmelanoma skin cancer of the head and neck: nonsurgical treatment. Facial Plast Surg Clin North Am. 2012;20(4):445-454.
    • (2012) Facial Plast Surg Clin North Am , vol.20 , Issue.4 , pp. 445-454
    • Ermertcan, A.T.1    Hellings, P.W.2    Cingi, C.3
  • 33
    • 33646167641 scopus 로고    scopus 로고
    • Current modalities and new advances in the treatment of basal cell carcinoma
    • Ceilley RI, Del Rosso JQ. Current modalities and new advances in the treatment of basal cell carcinoma. Int J Dermatol. 2006;45(5):489-498.
    • (2006) Int J Dermatol , vol.45 , Issue.5 , pp. 489-498
    • Ceilley, R.I.1    Del Rosso, J.Q.2
  • 34
    • 79960419826 scopus 로고    scopus 로고
    • The use of brachytherapy in the treatment of nonmelanoma skin cancer: A review
    • Alam M, Nanda S, Mittal BB, Kim NA, Yoo S. The use of brachytherapy in the treatment of nonmelanoma skin cancer: a review. J Am Acad Dermatol. 2011;65(2):377-388.
    • (2011) J Am Acad Dermatol , vol.65 , Issue.2 , pp. 377-388
    • Alam, M.1    Nanda, S.2    Mittal, B.B.3    Kim, N.A.4    Yoo, S.5
  • 35
    • 8244261275 scopus 로고    scopus 로고
    • Basal cell carcinoma of the face: Surgery or radiotherapy? Results of a randomized study
    • Avril MF, Auperin A, Margulis A, et al. Basal cell carcinoma of the face: surgery or radiotherapy? Results of a randomized study. Br J Cancer. 1997;76(1):100-106.
    • (1997) Br J Cancer , vol.76 , Issue.1 , pp. 100-106
    • Avril, M.F.1    Auperin, A.2    Margulis, A.3
  • 37
    • 0024538831 scopus 로고
    • Long-term recurrence rates in previously untreated (primary) basal cell carcinoma: Implications for patient follow-up
    • Rowe DE, Carroll RJ, Day CL Jr. Long-term recurrence rates in previously untreated (primary) basal cell carcinoma: implications for patient follow-up. J Dermatol Surg Oncol. 1989;15(3):315-328.
    • (1989) J Dermatol Surg Oncol , vol.15 , Issue.3 , pp. 315-328
    • Rowe, D.E.1    Carroll, R.J.2    Day Jr., C.L.3
  • 38
    • 0032740969 scopus 로고    scopus 로고
    • A systematic review of treatment modalities for primary basal cell carcinomas
    • Thissen MR, Neumann MH, Schouten LJ. A systematic review of treatment modalities for primary basal cell carcinomas. Arch Dermatol. 1999;135(10):1177-1183.
    • (1999) Arch Dermatol , vol.135 , Issue.10 , pp. 1177-1183
    • Thissen, M.R.1    Neumann, M.H.2    Schouten, L.J.3
  • 40
    • 0034034969 scopus 로고    scopus 로고
    • Evaluation of cosmetic results of a randomized trial comparing surgery and radiotherapy in the treatment of basal cell carcinoma of the face
    • Petit JY, Avril MF, Margulis A, et al. Evaluation of cosmetic results of a randomized trial comparing surgery and radiotherapy in the treatment of basal cell carcinoma of the face. Plast Reconstr Surg. 2000;105(7):2544-2551.
    • (2000) Plast Reconstr Surg , vol.105 , Issue.7 , pp. 2544-2551
    • Petit, J.Y.1    Avril, M.F.2    Margulis, A.3
  • 41
    • 24044514012 scopus 로고    scopus 로고
    • Postradiation sarcoma: Case report and review of the potential complications of therapeutic ionizing radiation
    • Fangman WL, Cook JL. Postradiation sarcoma: case report and review of the potential complications of therapeutic ionizing radiation. Dermatol Surg. 2005;31(8 Pt 1):966-972.
    • (2005) Dermatol Surg , vol.31 , Issue.8 PART 1 , pp. 966-972
    • Fangman, W.L.1    Cook, J.L.2
  • 42
    • 17444448286 scopus 로고    scopus 로고
    • Radiation dose as a risk factor for malignant melanoma following childhood cancer
    • Guerin S, Dupuy A, Anderson H, et al. Radiation dose as a risk factor for malignant melanoma following childhood cancer. Eur J Cancer. 2003;39(16):2379-2386.
    • (2003) Eur J Cancer , vol.39 , Issue.16 , pp. 2379-2386
    • Guerin, S.1    Dupuy, A.2    Anderson, H.3
  • 43
    • 0033897189 scopus 로고    scopus 로고
    • Therapeutic ionizing radiation and the incidence of basal cell carcinoma and squamous cell carcinoma
    • The New Hampshire Skin Cancer Study Group
    • Lichter MD, Karagas MR, Mott LA, Spencer SK, Stukel TA, Greenberg ER. Therapeutic ionizing radiation and the incidence of basal cell carcinoma and squamous cell carcinoma. The New Hampshire Skin Cancer Study Group. Arch Dermatol. 2000;136(8):1007-1011.
    • (2000) Arch Dermatol , vol.136 , Issue.8 , pp. 1007-1011
    • Lichter, M.D.1    Karagas, M.R.2    Mott, L.A.3    Spencer, S.K.4    Stukel, T.A.5    Greenberg, E.R.6
  • 44
    • 84877634426 scopus 로고    scopus 로고
    • Nontraditional management of basal cell carcinoma
    • Botto N, Rogers G. Nontraditional management of basal cell carcinoma. J Drugs Dermatol. 2013;12(5):525-532.
    • (2013) J Drugs Dermatol , vol.12 , Issue.5 , pp. 525-532
    • Botto, N.1    Rogers, G.2
  • 45
    • 84890893415 scopus 로고    scopus 로고
    • Bristol, TN: Graceway Pharmaceuticals, LLC; Available at
    • Aldara Cream [package insert]; Bristol, TN: Graceway Pharmaceuticals, LLC; 2010. Available at www.accessdata.fda.gov/drugsatfda-docs/ label/2010/020723s0022lbl.pdf. .
    • (2010) Aldara Cream [Package Insert]
  • 46
    • 2342473348 scopus 로고    scopus 로고
    • Imiquimod 5% cream for the treatment of superficial basal cell carcinoma: Results from two phase III, randomized, vehicle-controlled studies
    • Geisse J, Caro I, Lindholm J, Golitz L, Stampone P, Owens M. Imiquimod 5% cream for the treatment of superficial basal cell carcinoma: results from two phase III, randomized, vehicle-controlled studies. J Am Acad Dermatol. 2004;50(5):722-733.
    • (2004) J Am Acad Dermatol , vol.50 , Issue.5 , pp. 722-733
    • Geisse, J.1    Caro, I.2    Lindholm, J.3    Golitz, L.4    Stampone, P.5    Owens, M.6
  • 47
    • 18944395052 scopus 로고    scopus 로고
    • Imiquimod 5% cream for the treatment of superficial basal cell carcinoma: Results from a randomized vehiclecontrolled phase III study in Europe
    • Schulze HJ, Cribier B, Requena L, et al. Imiquimod 5% cream for the treatment of superficial basal cell carcinoma: results from a randomized vehiclecontrolled phase III study in Europe. Br J Dermatol. 2005;152(5):939-947.
    • (2005) Br J Dermatol , vol.152 , Issue.5 , pp. 939-947
    • Schulze, H.J.1    Cribier, B.2    Requena, L.3
  • 48
    • 57749201993 scopus 로고    scopus 로고
    • Recurrence rate of superficial basal cell carcinoma following treatment with imiquimod 5% cream: Conclusion of a 5-year long-term follow-up study in Europe
    • Gollnick H, Barona CG, Frank RG, et al. Recurrence rate of superficial basal cell carcinoma following treatment with imiquimod 5% cream: conclusion of a 5-year long-term follow-up study in Europe. Eur J Dermatol. 2008;18(6):677-682.
    • (2008) Eur J Dermatol , vol.18 , Issue.6 , pp. 677-682
    • Gollnick, H.1    Barona, C.G.2    Frank, R.G.3
  • 49
    • 77955778580 scopus 로고    scopus 로고
    • Sustained clearance of superficial basal cell carcinomas treated with imiquimod cream 5%: Results of a prospective 5-year study
    • Quirk C, Gebauer K, De'Ambrosis B, Slade HB, Meng TC. Sustained clearance of superficial basal cell carcinomas treated with imiquimod cream 5%: results of a prospective 5-year study. Cutis. 2010;85(6):318-324.
    • (2010) Cutis , vol.85 , Issue.6 , pp. 318-324
    • Quirk, C.1    Gebauer, K.2    De'Ambrosis, B.3    Slade, H.B.4    Meng, T.C.5
  • 50
    • 84867063990 scopus 로고    scopus 로고
    • Overall treatment success after treatment of primary superficial basal cell carcinoma: A systematic review and meta-analysis of randomized and nonrandomized trials
    • Roozeboom MH, Arits AH, Nelemans PJ, Kelleners-Smeets NW. Overall treatment success after treatment of primary superficial basal cell carcinoma: a systematic review and meta-analysis of randomized and nonrandomized trials. Br J Dermatol. 2012;167(4):733-756.
    • (2012) Br J Dermatol , vol.167 , Issue.4 , pp. 733-756
    • Roozeboom, M.H.1    Arits, A.H.2    Nelemans, P.J.3    Kelleners-Smeets, N.W.4
  • 51
    • 5444266559 scopus 로고    scopus 로고
    • 5% imiquimod cream for the treatment of large superficial basal cell carcinoma
    • Shumack S, Gebauer K, Quirk C, Macdonald K, Walters SA, Owens M. 5% imiquimod cream for the treatment of large superficial basal cell carcinoma. Arch Dermatol. 2004;140(10):1286-1287.
    • (2004) Arch Dermatol , vol.140 , Issue.10 , pp. 1286-1287
    • Shumack, S.1    Gebauer, K.2    Quirk, C.3    Macdonald, K.4    Walters, S.A.5    Owens, M.6
  • 52
    • 34548531036 scopus 로고    scopus 로고
    • A phase III, randomized, open label study to evaluate the safety and efficacy of imiquimod 5% cream applied thrice weekly for 8 and 12 weeks in the treatment of low-risk nodular basal cell carcinoma
    • Eigentler TK, Kamin A, Weide BM, et al. A phase III, randomized, open label study to evaluate the safety and efficacy of imiquimod 5% cream applied thrice weekly for 8 and 12 weeks in the treatment of low-risk nodular basal cell carcinoma. J Am Acad Dermatol. 2007;57(4):616-621.
    • (2007) J Am Acad Dermatol , vol.57 , Issue.4 , pp. 616-621
    • Eigentler, T.K.1    Kamin, A.2    Weide, B.M.3
  • 53
    • 18244384077 scopus 로고    scopus 로고
    • Imiquimod treatment of superficial and nodular basal cell carcinoma: 12-week open-label trial
    • Peris K, Campione E, Micantonio T, Marulli GC, Fargnoli MC, Chimenti S. Imiquimod treatment of superficial and nodular basal cell carcinoma: 12-week open-label trial. Dermatol Surg. 2005;31(3):318-323.
    • (2005) Dermatol Surg , vol.31 , Issue.3 , pp. 318-323
    • Peris, K.1    Campione, E.2    Micantonio, T.3    Marulli, G.C.4    Fargnoli, M.C.5    Chimenti, S.6
  • 54
    • 0036715342 scopus 로고    scopus 로고
    • Efficacy of topical 5% imiquimod cream for the treatment of nodular basal cell carcinoma: Comparison of dosing regimens
    • Shumack S, Robinson J, Kossard S, et al. Efficacy of topical 5% imiquimod cream for the treatment of nodular basal cell carcinoma: comparison of dosing regimens. Arch Dermatol. 2002;138(9):1165-1171.
    • (2002) Arch Dermatol , vol.138 , Issue.9 , pp. 1165-1171
    • Shumack, S.1    Robinson, J.2    Kossard, S.3
  • 55
    • 0036886426 scopus 로고    scopus 로고
    • Imiquimod 5% cream for the treatment of superficial and nodular basal cell carcinoma: Randomized studies comparing low-frequency dosing with and without occlusion
    • Sterry W, Ruzicka T, Herrera E, et al. Imiquimod 5% cream for the treatment of superficial and nodular basal cell carcinoma: randomized studies comparing low-frequency dosing with and without occlusion. Br J Dermatol. 2002;147(6):1227-1236.
    • (2002) Br J Dermatol , vol.147 , Issue.6 , pp. 1227-1236
    • Sterry, W.1    Ruzicka, T.2    Herrera, E.3
  • 56
    • 58149293337 scopus 로고    scopus 로고
    • Imiquimod 5% cream as adjunctive therapy for primary, solitary, nodular nasal basal cell carcinomas before Mohs micrographic surgery: A randomized, double blind, vehicle-controlled study
    • Butler DF, Parekh PK, Lenis A. Imiquimod 5% cream as adjunctive therapy for primary, solitary, nodular nasal basal cell carcinomas before Mohs micrographic surgery: a randomized, double blind, vehicle-controlled study. Dermatol Surg. 2009;35(1):24-29.
    • (2009) Dermatol Surg , vol.35 , Issue.1 , pp. 24-29
    • Butler, D.F.1    Parekh, P.K.2    Lenis, A.3
  • 57
    • 33645802442 scopus 로고    scopus 로고
    • Pilot study of imiquimod 5% cream as adjunctive therapy to curettage and electrodesiccation for nodular basal cell carcinoma
    • Spencer JM. Pilot study of imiquimod 5% cream as adjunctive therapy to curettage and electrodesiccation for nodular basal cell carcinoma. Dermatol Surg. 2006;32(1):63-69.
    • (2006) Dermatol Surg , vol.32 , Issue.1 , pp. 63-69
    • Spencer, J.M.1
  • 58
    • 77949930463 scopus 로고    scopus 로고
    • Imiquimod 5% cream for the treatment of periocular Basal cell carcinoma
    • Carneiro RC, de Macedo EM, Matayoshi S. Imiquimod 5% cream for the treatment of periocular Basal cell carcinoma. Ophthal Plast Reconstr Surg. 2010;26(2):100-102.
    • (2010) Ophthal Plast Reconstr Surg , vol.26 , Issue.2 , pp. 100-102
    • Carneiro, R.C.1    De Macedo, E.M.2    Matayoshi, S.3
  • 60
    • 79951724288 scopus 로고    scopus 로고
    • Long-term outcome after treatment with 5% topical imiquimod cream in patients with basal cell carcinoma of the eyelids
    • Prokosch V, Thanos S, Spaniol K, Stupp T. Long-term outcome after treatment with 5% topical imiquimod cream in patients with basal cell carcinoma of the eyelids. Graefes Arch Clin Exp Ophthalamol. 2011;249(1):121-125.
    • (2011) Graefes Arch Clin Exp Ophthalamol , vol.249 , Issue.1 , pp. 121-125
    • Prokosch, V.1    Thanos, S.2    Spaniol, K.3    Stupp, T.4
  • 63
    • 34147123685 scopus 로고    scopus 로고
    • 5% 5-Fluorouracil cream for the treatment of small superficial Basal cell carcinoma: Efficacy, tolerability, cosmetic outcome, and patient satisfaction
    • discussion 440
    • Gross K, Kircik L, Kricorian G. 5% 5-Fluorouracil cream for the treatment of small superficial Basal cell carcinoma: efficacy, tolerability, cosmetic outcome, and patient satisfaction. Dermatol Surg. 2007;33(4):433-439; discussion 440.
    • (2007) Dermatol Surg , vol.33 , Issue.4 , pp. 433-439
    • Gross, K.1    Kircik, L.2    Kricorian, G.3
  • 64
    • 0031038493 scopus 로고    scopus 로고
    • Nonsurgical treatment of basal cell carcinomas with intralesional 5-fluorouracil/epinephrine injectable gel
    • Miller BH, Shavin JS, Cognetta A, et al. Nonsurgical treatment of basal cell carcinomas with intralesional 5-fluorouracil/epinephrine injectable gel. J Am Acad Dermatol. 1997;36(1):72-77.
    • (1997) J Am Acad Dermatol , vol.36 , Issue.1 , pp. 72-77
    • Miller, B.H.1    Shavin, J.S.2    Cognetta, A.3
  • 65
    • 0021920469 scopus 로고
    • Fluorouracil paste treatment of thin basal cell carcinomas
    • Epstein E. Fluorouracil paste treatment of thin basal cell carcinomas. Arch Dermatol. 1985;121(2):207-213.
    • (1985) Arch Dermatol , vol.121 , Issue.2 , pp. 207-213
    • Epstein, E.1
  • 66
    • 0018768696 scopus 로고
    • Treatment of basal cell carcinoma of the skin with 5-fluorouracil ointment. A 10-year follow-up study
    • Reymann F. Treatment of basal cell carcinoma of the skin with 5-fluorouracil ointment. A 10-year follow-up study. Dermatologica. 1979;158(5):368-372.
    • (1979) Dermatologica , vol.158 , Issue.5 , pp. 368-372
    • Reymann, F.1
  • 67
    • 84861722221 scopus 로고    scopus 로고
    • Ingenol mebutate: An introduction
    • Fallen RS, Gooderham M. Ingenol mebutate: an introduction. Skin Therapy Lett. 2012;17(2):1-3.
    • (2012) Skin Therapy Lett , vol.17 , Issue.2 , pp. 1-3
    • Fallen, R.S.1    Gooderham, M.2
  • 68
    • 77951989505 scopus 로고    scopus 로고
    • PEP005 (ingenol mebutate) gel for the topical treatment of superficial basal cell carcinoma: Results of a randomized phase IIa trial
    • Siller G, Rosen R, Freeman M, Welburn P, Katsamas J, Ogbourne SM. PEP005 (ingenol mebutate) gel for the topical treatment of superficial basal cell carcinoma: results of a randomized phase IIa trial. Australas J Dermatol. 2010;51(2):99-105.
    • (2010) Australas J Dermatol , vol.51 , Issue.2 , pp. 99-105
    • Siller, G.1    Rosen, R.2    Freeman, M.3    Welburn, P.4    Katsamas, J.5    Ogbourne, S.M.6
  • 69
    • 33845701344 scopus 로고    scopus 로고
    • Guidelines on the use of photodynamic therapy for nonmelanoma skin cancer: An international consensus. International Society for Photodynamic Therapy in Dermatology, 2005
    • Braathen LR, Szeimies RM, Basset-Seguin N, et al. Guidelines on the use of photodynamic therapy for nonmelanoma skin cancer: an international consensus. International Society for Photodynamic Therapy in Dermatology, 2005. J Am Acad Dermatol. 2007;56(1):125-143.
    • (2007) J Am Acad Dermatol , vol.56 , Issue.1 , pp. 125-143
    • Braathen, L.R.1    Szeimies, R.M.2    Basset-Seguin, N.3
  • 70
    • 56549129972 scopus 로고    scopus 로고
    • Guidelines for topical photodynamic therapy: Update
    • British Association of Dermatologists Therapy G, Audit S, the British Photodermatology G
    • Morton CA, McKenna KE, Rhodes LE, British Association of Dermatologists Therapy G, Audit S, the British Photodermatology G. Guidelines for topical photodynamic therapy: update. Br J Dermatol. 2008;159(6):1245-1266.
    • (2008) Br J Dermatol , vol.159 , Issue.6 , pp. 1245-1266
    • Morton, C.A.1    McKenna, K.E.2    Rhodes, L.E.3
  • 71
    • 0034522313 scopus 로고    scopus 로고
    • Routine double treatments of superficial basal cell carcinomas using aminolaevulinic acid-based photodynamic therapy
    • Haller JC, Cairnduff F, Slack G, et al. Routine double treatments of superficial basal cell carcinomas using aminolaevulinic acid-based photodynamic therapy. Br J Dermatol. 2000;143(6):1270-1275.
    • (2000) Br J Dermatol , vol.143 , Issue.6 , pp. 1270-1275
    • Haller, J.C.1    Cairnduff, F.2    Slack, G.3
  • 72
    • 84887075605 scopus 로고    scopus 로고
    • Consensus recommendations for the treatment of basal cell carcinomas in Gorlin syndrome with topical methylaminolaevulinate-photodynamic therapy
    • April 13. [Epub ahead of print]
    • Basset-Seguin N, Bissonnette R, Girard C, et al. Consensus recommendations for the treatment of basal cell carcinomas in Gorlin syndrome with topical methylaminolaevulinate-photodynamic therapy. J Eur Acad Dermatol Venereol. 2013 April 13. [Epub ahead of print].
    • (2013) J Eur Acad Dermatol Venereol
    • Basset-Seguin, N.1    Bissonnette, R.2    Girard, C.3
  • 73
    • 0342382121 scopus 로고    scopus 로고
    • Available at Accessed September 9, 2013
    • American Cancer Society. Photodynamic therapy. Available at http://www.cancer.org/treatment/treatmentsandsideeffects/treatmenttypes/ photodynamic-therapy. Accessed September 9, 2013.
    • Photodynamic Therapy
  • 74
    • 52649102554 scopus 로고    scopus 로고
    • Topical methyl aminolaevulinate photodynamic therapy versus cryotherapy for superficial basal cell carcinoma: A 5 year randomized trial
    • Basset-Seguin N, Ibbotson SH, Emtestam L, et al. Topical methyl aminolaevulinate photodynamic therapy versus cryotherapy for superficial basal cell carcinoma: a 5 year randomized trial. Eur J Dermatol. 2008;18(5):547-553.
    • (2008) Eur J Dermatol , vol.18 , Issue.5 , pp. 547-553
    • Basset-Seguin, N.1    Ibbotson, S.H.2    Emtestam, L.3
  • 75
    • 35548931472 scopus 로고    scopus 로고
    • Randomized phase II trial of firstline treatment with sorafenib versus interferon in patients with advanced renal cell carcinoma: Final results
    • Abstract 5025
    • Szczylik C, Demkow T, Staehler WM, et al. Randomized phase II trial of firstline treatment with sorafenib versus interferon in patients with advanced renal cell carcinoma: final results. J Clin Oncol. 2007;25(18S). Abstract 5025.
    • (2007) J Clin Oncol , vol.25 , Issue.18 S
    • Szczylik, C.1    Demkow, T.2    Staehler, W.M.3
  • 76
    • 9144262975 scopus 로고    scopus 로고
    • Photodynamic therapy using topical methyl aminolevulinate vs surgery for nodular basal cell carcinoma: Results of a multicenter randomized prospective trial
    • Rhodes LE, de Rie M, Enstrom Y, et al. Photodynamic therapy using topical methyl aminolevulinate vs surgery for nodular basal cell carcinoma: results of a multicenter randomized prospective trial. Arch Dermatol. 2004;140(1):17-23.
    • (2004) Arch Dermatol , vol.140 , Issue.1 , pp. 17-23
    • Rhodes, L.E.1    De Rie, M.2    Enstrom, Y.3
  • 77
    • 9144228152 scopus 로고    scopus 로고
    • Topical methyl aminolaevulinate photodynamic therapy in patients with basal cell carcinoma prone to complications and poor cosmetic outcome with conventional treatment
    • Horn M, Wolf P, Wulf HC, et al. Topical methyl aminolaevulinate photodynamic therapy in patients with basal cell carcinoma prone to complications and poor cosmetic outcome with conventional treatment. Br J Dermatol. 2003;149(6):1242-1249.
    • (2003) Br J Dermatol , vol.149 , Issue.6 , pp. 1242-1249
    • Horn, M.1    Wolf, P.2    Wulf, H.C.3
  • 78
    • 20244366385 scopus 로고    scopus 로고
    • Photodynamic therapy with topical methyl aminolaevulinate for 'difficult-to-treat' basal cell carcinoma
    • Vinciullo C, Elliott T, Francis D, et al. Photodynamic therapy with topical methyl aminolaevulinate for 'difficult-to-treat' basal cell carcinoma. Br J Dermatol. 2005;152(4):765-772.
    • (2005) Br J Dermatol , vol.152 , Issue.4 , pp. 765-772
    • Vinciullo, C.1    Elliott, T.2    Francis, D.3
  • 79
    • 53749103876 scopus 로고    scopus 로고
    • A clinical study comparing methyl aminolevulinate photodynamic therapy and surgery in small superficial basal cell carcinoma (8-20 mm), with a 12-month follow-up
    • Szeimies RM, Ibbotson S, Murrell DF, et al. A clinical study comparing methyl aminolevulinate photodynamic therapy and surgery in small superficial basal cell carcinoma (8-20 mm), with a 12-month follow-up. J Eur AcadDermatol Venereol. 2008;22(11):1302-1311.
    • (2008) J Eur AcadDermatol Venereol , vol.22 , Issue.11 , pp. 1302-1311
    • Szeimies, R.M.1    Ibbotson, S.2    Murrell, D.F.3
  • 80
    • 34548850373 scopus 로고    scopus 로고
    • Five-year follow-up of a randomized, prospective trial of topical methyl aminolevulinate photodynamic therapy vs surgery for nodular basal cell carcinoma
    • Rhodes LE, de Rie MA, Leifsdottir R, et al. Five-year follow-up of a randomized, prospective trial of topical methyl aminolevulinate photodynamic therapy vs surgery for nodular basal cell carcinoma. Arch Dermatol. 2007;143(9):1131-1136.
    • (2007) Arch Dermatol , vol.143 , Issue.9 , pp. 1131-1136
    • Rhodes, L.E.1    De Rie, M.A.2    Leifsdottir, R.3
  • 81
    • 84866981561 scopus 로고    scopus 로고
    • South San Francisco, CA: Genentech USA, Inc.; Available at
    • Erivedge [package insert]; South San Francisco, CA: Genentech USA, Inc.; 2012.Available at www.accessdata.fda.gov/drugsatfda-docs/label/2012/203388lbl. pdf.
    • (2012) Erivedge [Package Insert]
  • 82
    • 84877089372 scopus 로고    scopus 로고
    • U.S. Food and Drug Administration approval: Vismodegib for recurrent, locally advanced, or metastatic basal cell carcinoma
    • Axelson M, Liu K, Jiang X, et al. U.S. Food and Drug Administration approval: vismodegib for recurrent, locally advanced, or metastatic basal cell carcinoma. Clin Cancer Res. 2013;19(9):2289-2293.
    • (2013) Clin Cancer Res , vol.19 , Issue.9 , pp. 2289-2293
    • Axelson, M.1    Liu, K.2    Jiang, X.3
  • 83
    • 19944433687 scopus 로고    scopus 로고
    • Somatic mutations in the PTCH, SMOH, SUFUH and TP53 genes in sporadic basal cell carcinomas
    • Reifenberger J, Wolter M, Knobbe CB, et al. Somatic mutations in the PTCH, SMOH, SUFUH and TP53 genes in sporadic basal cell carcinomas. Br J Dermatol. 2005;152(1):43-51.
    • (2005) Br J Dermatol , vol.152 , Issue.1 , pp. 43-51
    • Reifenberger, J.1    Wolter, M.2    Knobbe, C.B.3
  • 84
    • 84866244250 scopus 로고    scopus 로고
    • Gorlin-Goltz syndrome - A medical condition requiring a multidisciplinary approach
    • Kiwilsza M, Sporniak-Tutak K. Gorlin-Goltz syndrome - a medical condition requiring a multidisciplinary approach. Med Sci Monit. 2012;18(9):RA145-153.
    • (2012) Med Sci Monit , vol.18 , Issue.9
    • Kiwilsza, M.1    Sporniak-Tutak, K.2
  • 85
    • 77954227128 scopus 로고    scopus 로고
    • The role of the hedgehog signaling pathway in the development of basal cell carcinoma and opportunities for treatment
    • Caro I, Low JA. The role of the hedgehog signaling pathway in the development of basal cell carcinoma and opportunities for treatment. Clin Cancer Res. 2010;16(13):3335-3339.
    • (2010) Clin Cancer Res , vol.16 , Issue.13 , pp. 3335-3339
    • Caro, I.1    Low, J.A.2
  • 86
    • 77951995826 scopus 로고    scopus 로고
    • Genetics of basal cell carcinoma
    • quiz 93-84
    • de Zwaan SE, Haass NK. Genetics of basal cell carcinoma. Australas J Dermatol. 2010;51(2):81-92; quiz 93-84.
    • (2010) Australas J Dermatol , vol.51 , Issue.2 , pp. 81-92
    • De Zwaan, S.E.1    Haass, N.K.2
  • 87
    • 84865986389 scopus 로고    scopus 로고
    • Targeting Hedgehog signaling and understanding refractory response to treatment with Hedgehog pathway inhibitors
    • Queiroz KC, Spek CA, Peppelenbosch MP. Targeting Hedgehog signaling and understanding refractory response to treatment with Hedgehog pathway inhibitors. Drug Resist Updat. 2012;15(4):211-222.
    • (2012) Drug Resist Updat , vol.15 , Issue.4 , pp. 211-222
    • Queiroz, K.C.1    Spek, C.A.2    Peppelenbosch, M.P.3
  • 89
    • 0025332468 scopus 로고
    • Metastatic basal cell carcinoma: Response to chemotherapy
    • Bason MM, Grant-Kels JM, Govil M. Metastatic basal cell carcinoma: response to chemotherapy. J Am Acad Dermatol. 1990;22(5 Pt 2):905-908.
    • (1990) J Am Acad Dermatol , vol.22 , Issue.5 PART 2 , pp. 905-908
    • Bason, M.M.1    Grant-Kels, J.M.2    Govil, M.3
  • 90
    • 33745317180 scopus 로고    scopus 로고
    • Metastatic basal cell carcinoma: Complete response to chemotherapy and associated pure red cell aplasia
    • Carneiro BA, Watkin WG, Mehta UK, Brockstein BE. Metastatic basal cell carcinoma: complete response to chemotherapy and associated pure red cell aplasia. Cancer Invest. 2006;24(4):396-400.
    • (2006) Cancer Invest , vol.24 , Issue.4 , pp. 396-400
    • Carneiro, B.A.1    Watkin, W.G.2    Mehta, U.K.3    Brockstein, B.E.4
  • 91
    • 0021969870 scopus 로고
    • Cisplatin and doxorubicin. An effective chemotherapy combination in the treatment of advanced basal cell and squamous carcinoma of the skin
    • Guthrie TH Jr, McElveen LJ, Porubsky ES, Harmon JD. Cisplatin and doxorubicin. An effective chemotherapy combination in the treatment of advanced basal cell and squamous carcinoma of the skin. Cancer. 1985;55(8):1629-1632.
    • (1985) Cancer , vol.55 , Issue.8 , pp. 1629-1632
    • Guthrie Jr., T.H.1    McElveen, L.J.2    Porubsky, E.S.3    Harmon, J.D.4
  • 92
    • 4444381037 scopus 로고    scopus 로고
    • Metastatic basal cell carcinoma: Rapid symptomatic response to cisplatin and paclitaxel
    • Jefford M, Kiffer JD, Somers G, Daniel FJ, Davis ID. Metastatic basal cell carcinoma: rapid symptomatic response to cisplatin and paclitaxel. ANZ J Surg. 2004;74(8):704-705.
    • (2004) ANZ J Surg , vol.74 , Issue.8 , pp. 704-705
    • Jefford, M.1    Kiffer, J.D.2    Somers, G.3    Daniel, F.J.4    Davis, I.D.5
  • 93
    • 0029977921 scopus 로고    scopus 로고
    • Platinum-based cytotoxic therapy in basal cell carcinoma - A review of the literature
    • Moeholt K, Aagaard H, Pfeiffer P, Hansen O. Platinum-based cytotoxic therapy in basal cell carcinoma - a review of the literature. Acta Oncol. 1996;35(6):677-682.
    • (1996) Acta Oncol , vol.35 , Issue.6 , pp. 677-682
    • Moeholt, K.1    Aagaard, H.2    Pfeiffer, P.3    Hansen, O.4
  • 94
    • 0020610834 scopus 로고
    • Responsiveness of metastatic basalcell carcinoma to chemotherapy. A case report
    • Wieman TJ, Shively EH, Woodcock TM. Responsiveness of metastatic basalcell carcinoma to chemotherapy. A case report. Cancer. 1983;52(9):1583- 1585.
    • (1983) Cancer , vol.52 , Issue.9 , pp. 1583-1585
    • Wieman, T.J.1    Shively, E.H.2    Woodcock, T.M.3
  • 95
    • 79952768073 scopus 로고    scopus 로고
    • An overview of Mohs micrographic surgery for the treatment of basal cell carcinoma
    • Wood LD, Ammirati CT. An overview of Mohs micrographic surgery for the treatment of basal cell carcinoma. Dermatol Clin. 2011;29(2):153-160, vii.
    • (2011) Dermatol Clin , vol.29 , Issue.2
    • Wood, L.D.1    Ammirati, C.T.2
  • 96
    • 69949084378 scopus 로고    scopus 로고
    • GDC-0449-a potent inhibitor of the hedgehog pathway
    • Robarge KD, Brunton SA, Castanedo GM, et al. GDC-0449-a potent inhibitor of the hedgehog pathway. Bioorg Med Chem Lett. 2009;19(19):5576-5581.
    • (2009) Bioorg Med Chem Lett , vol.19 , Issue.19 , pp. 5576-5581
    • Robarge, K.D.1    Brunton, S.A.2    Castanedo, G.M.3
  • 97
    • 78649647341 scopus 로고    scopus 로고
    • Hedgehog antagonist GDC-0449 is effective in the treatment of advanced basal cell carcinoma
    • Amin SH, Tibes R, Kim JE, Hybarger CP. Hedgehog antagonist GDC-0449 is effective in the treatment of advanced basal cell carcinoma. Laryngoscope. 2010;120(12):2456-2459.
    • (2010) Laryngoscope , vol.120 , Issue.12 , pp. 2456-2459
    • Amin, S.H.1    Tibes, R.2    Kim, J.E.3    Hybarger, C.P.4
  • 98
    • 79954611501 scopus 로고    scopus 로고
    • Phase I trial of hedgehog pathway inhibitor vismodegib (GDC-0449) in patients with refractory, locally advanced or metastatic solid tumors
    • LoRusso PM, Rudin CM, Reddy JC, et al. Phase I trial of hedgehog pathway inhibitor vismodegib (GDC-0449) in patients with refractory, locally advanced or metastatic solid tumors. Clin Cancer Res. 2011;17(8):2502-2511.
    • (2011) Clin Cancer Res , vol.17 , Issue.8 , pp. 2502-2511
    • LoRusso, P.M.1    Rudin, C.M.2    Reddy, J.C.3
  • 99
    • 70349238733 scopus 로고    scopus 로고
    • Inhibition of the hedgehog pathway in advanced basal-cell carcinoma
    • Von Hoff DD, LoRusso PM, Rudin CM, et al. Inhibition of the hedgehog pathway in advanced basal-cell carcinoma. N Engl J Med. 2009;361(12):1164-1172.
    • (2009) N Engl J Med , vol.361 , Issue.12 , pp. 1164-1172
    • Von Hoff, D.D.1    LoRusso, P.M.2    Rudin, C.M.3
  • 100
    • 80052475002 scopus 로고    scopus 로고
    • Pharmacokinetic dose-scheduling study of hedgehog pathway inhibitor vismodegib (GDC-0449) in patients with locally advanced or metastatic solid tumors
    • Lorusso PM, Jimeno A, Dy G, et al. Pharmacokinetic dose-scheduling study of hedgehog pathway inhibitor vismodegib (GDC-0449) in patients with locally advanced or metastatic solid tumors. Clin Cancer Res. 2011;17(17):5774-5782.
    • (2011) Clin Cancer Res , vol.17 , Issue.17 , pp. 5774-5782
    • Lorusso, P.M.1    Jimeno, A.2    Dy, G.3
  • 101
    • 84872323415 scopus 로고    scopus 로고
    • Co-administration of vismodegib with rosiglitazone or combined oral contraceptive in patients with locally advanced or metastatic solid tumors: A pharmacokinetic assessment of drugdrug interaction potential
    • LoRusso PM, Piha-Paul SA, Mita M, et al. Co-administration of vismodegib with rosiglitazone or combined oral contraceptive in patients with locally advanced or metastatic solid tumors: a pharmacokinetic assessment of drugdrug interaction potential. Cancer Chemother Pharmacol. 2013;71(1):193-202.
    • (2013) Cancer Chemother Pharmacol , vol.71 , Issue.1 , pp. 193-202
    • LoRusso, P.M.1    Piha-Paul, S.A.2    Mita, M.3
  • 102
    • 84861856844 scopus 로고    scopus 로고
    • Efficacy and safety of vismodegib in advanced basal-cell carcinoma
    • Sekulic A, Migden MR, Oro AE, et al. Efficacy and safety of vismodegib in advanced basal-cell carcinoma. N Engl J Med. 2012;366(23):2171-2179.
    • (2012) N Engl J Med , vol.366 , Issue.23 , pp. 2171-2179
    • Sekulic, A.1    Migden, M.R.2    Oro, A.E.3
  • 103
    • 0344837756 scopus 로고    scopus 로고
    • Disruption of sonic hedgehog signaling alters growth and patterning of lingual taste papillae
    • Hall JM, Bell ML, Finger TE. Disruption of sonic hedgehog signaling alters growth and patterning of lingual taste papillae. Dev Biol. 2003;255(2):263-277.
    • (2003) Dev Biol , vol.255 , Issue.2 , pp. 263-277
    • Hall, J.M.1    Bell, M.L.2    Finger, T.E.3
  • 104
    • 9944225812 scopus 로고    scopus 로고
    • Sonic hedgehog exerts distinct, stage-specific effects on tongue and taste papilla development
    • Liu HX, Maccallum DK, Edwards C, Gaffield W, Mistretta CM. Sonic hedgehog exerts distinct, stage-specific effects on tongue and taste papilla development. Dev Biol. 2004;276(2):280-300.
    • (2004) Dev Biol , vol.276 , Issue.2 , pp. 280-300
    • Liu, H.X.1    Maccallum, D.K.2    Edwards, C.3    Gaffield, W.4    Mistretta, C.M.5
  • 105
    • 0032953901 scopus 로고    scopus 로고
    • Essential role for Sonic hedgehog during hair follicle morphogenesis
    • Chiang C, Swan RZ, Grachtchouk M, et al. Essential role for Sonic hedgehog during hair follicle morphogenesis. Dev Biol. 1999;205(1):1-9.
    • (1999) Dev Biol , vol.205 , Issue.1 , pp. 1-9
    • Chiang, C.1    Swan, R.Z.2    Grachtchouk, M.3
  • 107
    • 77649337790 scopus 로고    scopus 로고
    • Hedgehog beyond medulloblastoma and basal cell carcinoma
    • Teglund S, Toftgard R. Hedgehog beyond medulloblastoma and basal cell carcinoma. Biochim Biophys Acta. 2010;1805(2):181-208.
    • (2010) Biochim Biophys Acta , vol.1805 , Issue.2 , pp. 181-208
    • Teglund, S.1    Toftgard, R.2
  • 109
    • 84861876867 scopus 로고    scopus 로고
    • Inhibiting the hedgehog pathway in patients with the basal-cell nevus syndrome
    • Tang JY, Mackay-Wiggan JM, Aszterbaum M, et al. Inhibiting the hedgehog pathway in patients with the basal-cell nevus syndrome. N Engl J Med. 2012;366(23):2180-2188.
    • (2012) N Engl J Med , vol.366 , Issue.23 , pp. 2180-2188
    • Tang, J.Y.1    Mackay-Wiggan, J.M.2    Aszterbaum, M.3
  • 110
    • 84885456754 scopus 로고    scopus 로고
    • Preliminary results of a Phase 2 trial evaluating efficacy and saefty of vismodegib (GDC-0449) in operable basal cell carcinoma
    • abstr 543
    • Gross KG, Sofen H, Goldberg LH, et al. Preliminary results of a Phase 2 trial evaluating efficacy and saefty of vismodegib (GDC-0449) in operable basal cell carcinoma. J Invest Dermatol 2012;132:S92; abstr 543.
    • (2012) J Invest Dermatol , vol.132
    • Gross, K.G.1    Sofen, H.2    Goldberg, L.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.