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Volumn 65, Issue SUPPL.1, 2014, Pages

Ethical issues in adolescent HIV research in resource-limited countries

Author keywords

Adolescents; Ethics; Informed consent

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; CLINICAL RESEARCH; DEVELOPING COUNTRY; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; PEDIATRICS; PRIORITY JOURNAL; RESEARCH ETHICS; RESEARCH SUBJECT; SCIENTIST; VULNERABLE POPULATION; YOUNG ADULT; ADOLESCENT HEALTH; HEALTH CARE PLANNING; HIGH RISK POPULATION; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; INFECTION RISK; INFORMED CONSENT; LAW; MANDATORY REPORTING; MEDICAL AUDIT; MEDICAL RESEARCH; PARENTAL CONSENT; PRIVACY; RISK ASSESSMENT;

EID: 84890936129     PISSN: 15254135     EISSN: 10779450     Source Type: Journal    
DOI: 10.1097/QAI.0000000000000036     Document Type: Article
Times cited : (30)

References (40)
  • 1
    • 84890945168 scopus 로고    scopus 로고
    • Accessed August 1, 2013
    • UNAIDS. Fact Sheet-2012. Available at: http://www.unaids. org/en/media/unaids/contentassets/documents/factsheet/2012/20120417-FS- adolescentsyoungpeoplehiv-en.pdf. Accessed August 1, 2013.
    • Fact Sheet-2012
  • 2
    • 84858139266 scopus 로고    scopus 로고
    • World Health Organization and Joint United Nations Programme on HIV/AIDS. Accessed August 1, 2013
    • World Health Organization and Joint United Nations Programme on HIV/AIDS. Global HIV/AIDS response: epidemic update and health sector progress towards Universal Access. Available at: http://www. unaids.org/en/media/unaids/ contentassets/documents/unaidspublication/ 2011/20111130-ua-report-en.pdf. Accessed August 1, 2013.
    • Global HIV/AIDS Response: Epidemic Update and Health Sector Progress Towards Universal Access
  • 4
    • 1542357579 scopus 로고    scopus 로고
    • Ethical conduct of research in resource-limited settings
    • DOI 10.1086/381711
    • Kuritzkes D. Ethical conducts of research in resource-limited settings. J Infect Dis. 2004;189: 764-765. (Pubitemid 38328175)
    • (2004) Journal of Infectious Diseases , vol.189 , Issue.5 , pp. 764-765
    • Kuritzkes, D.R.1
  • 5
    • 77954042076 scopus 로고    scopus 로고
    • Ethical and regulatory considerations for the inclusion of adolescents in HIV biomedical prevention research
    • Nelson RM, Lewis LL, Struble K, et al. Ethical and regulatory considerations for the inclusion of adolescents in HIV biomedical prevention research. J Acquir Immune Defic Syndr. 2010;54:S18-S24.
    • (2010) J Acquir Immune Defic Syndr , vol.54
    • Nelson, R.M.1    Lewis, L.L.2    Struble, K.3
  • 6
    • 84890133032 scopus 로고    scopus 로고
    • Preventive misconception and adolescents' knowledge about HIV vaccine trials
    • [Epub ahead of print; January 25, 2013; doi: 10.1136/medethics-2012- 100821]
    • Ott MA, Alexander AB, Lally M, et al. Preventive misconception and adolescents' knowledge about HIV vaccine trials.J Med Ethics. 2013; [Epub ahead of print; January 25, 2013; doi: 10.1136/medethics-2012-100821].
    • (2013) J Med Ethics
    • Ott, M.A.1    Alexander, A.B.2    Lally, M.3
  • 7
    • 84902462975 scopus 로고    scopus 로고
    • "Youth friendly" clinics: Considerations for linking and engaging HIV-infected adolescents into care
    • [Epub ahead of print; June 20, 2013]
    • Tanner AE, Philbin MM, Duval A, et al. "Youth friendly" clinics: considerations for linking and engaging HIV-infected adolescents into care. AIDS Care. 2013; [Epub ahead of print; June 20, 2013].
    • (2013) AIDS Care
    • Tanner, A.E.1    Philbin, M.M.2    Duval, A.3
  • 8
    • 84891372459 scopus 로고    scopus 로고
    • Linking HIV-positive adolescents to care in 15 different clinics across the United States: Creating solutions to address structural barriers for linkage to care
    • [Epub ahead of print; June 18, 2013]
    • Philbin MM, Tanner AE, Duval A, et al. Linking HIV-positive adolescents to care in 15 different clinics across the United States: creating solutions to address structural barriers for linkage to care. AIDS Care. 2013; [Epub ahead of print; June 18, 2013].
    • (2013) AIDS Care
    • Philbin, M.M.1    Tanner, A.E.2    Duval, A.3
  • 9
    • 84890953560 scopus 로고    scopus 로고
    • Mental health care among HIVinfected youth in medical care: Disparities and equalities
    • [Epub ahead of print; May 21, 2013]
    • Whiteley L, Brown L, Swenson R, et al. Mental health care among HIVinfected youth in medical care: disparities and equalities. J Intl Assoc Physicians AIDS Care. 2013; [Epub ahead of print; May 21, 2013].
    • (2013) J Intl Assoc Physicians AIDS Care
    • Whiteley, L.1    Brown, L.2    Swenson, R.3
  • 10
    • 84878183843 scopus 로고    scopus 로고
    • Comprehension of a simplified assent form in a vaccine trial for adolescents
    • Lee S, Kapogiannis B, Flynn P, et al. Comprehension of a simplified assent form in a vaccine trial for adolescents. J Med Ethics. 2013;39: 410-412.
    • (2013) J Med Ethics , vol.39 , pp. 410-412
    • Lee, S.1    Kapogiannis, B.2    Flynn, P.3
  • 11
    • 85027952615 scopus 로고    scopus 로고
    • The acceptability and feasibility of an HIV preexposure prophylaxis (PrEP) trial with young men who have sex with men
    • Hosek S, Siberry G, Bell M, et al. The acceptability and feasibility of an HIV preexposure prophylaxis (PrEP) trial with young men who have sex with men. J Acquir Immune Defic Syndr. 2013;62:447.
    • (2013) J Acquir Immune Defic Syndr , vol.62 , pp. 447
    • Hosek, S.1    Siberry, G.2    Bell, M.3
  • 12
    • 84875644597 scopus 로고    scopus 로고
    • HIV pre-exposure prophylaxis in adolescents at risk: Is an ounce of prevention worth a pound of cure?
    • Pace JE, Siberry GK, Hazra R, et al. HIV pre-exposure prophylaxis in adolescents at risk: is an ounce of prevention worth a pound of cure? Clin Infect Dis. 2013;56: 1149-1155.
    • (2013) Clin Infect Dis , vol.56 , pp. 1149-1155
    • Pace, J.E.1    Siberry, G.K.2    Hazra, R.3
  • 14
    • 34547891930 scopus 로고    scopus 로고
    • Rolling up our sleeves now to reap the benefits later: Preparing the community for an adolescent HIV vaccine
    • DOI 10.1097/COH.0b013e3282cecf0a, PII 0122292920070900000004
    • Kapogiannis BG, Lee SS. Rolling up our sleeves now to reap the benefits later: preparing the community for an adolescent HIV vaccine. Curr Opin HIV AIDS. 2007;2: 375-384. (Pubitemid 47254732)
    • (2007) Current Opinion in HIV and AIDS , vol.2 , Issue.5 , pp. 375-384
    • Kapogiannis, B.G.1    Lee, S.S.2
  • 15
    • 84868460128 scopus 로고    scopus 로고
    • HIV incidence in young girls in KwaZulu-Natal, South Africa-public health imperative for their inclusion in HIV biomedical intervention trials
    • Abdool Karim Q, Kharsany AB, Frohlich JA, et al. HIV incidence in young girls in KwaZulu-Natal, South Africa-public health imperative for their inclusion in HIV biomedical intervention trials. AIDS Behav. 2012; 16: 1870-1876.
    • (2012) AIDS Behav , vol.16 , pp. 1870-1876
    • Abdool Karim, Q.1    Kharsany, A.B.2    Frohlich, J.A.3
  • 17
    • 1542357575 scopus 로고    scopus 로고
    • What makes clinical research in developing countries ethical? The benchmarks of ethical research
    • DOI 10.1086/381709
    • Emanuel EJ, Wendler D, Killen J, et al. What makes clinical research in developing countries ethical? The benchmarks of ethical research. J Infect Dis. 2004:189: 930-937. (Pubitemid 38328195)
    • (2004) Journal of Infectious Diseases , vol.189 , Issue.5 , pp. 930-937
    • Emanuel, E.J.1    Wendler, D.2    Killen, J.3    Grady, C.4
  • 18
    • 84858065957 scopus 로고    scopus 로고
    • UNAIDS/AVAC, Geneva: UNAIDS, Accessed August 1, 2013
    • UNAIDS/AVAC (2011). Good participatory practice: guidelines for biomedical HIV prevention trials. Geneva: UNAIDS. Available at: http:// www.unaids.org/en/media/unaids/contentassets/documents/unaidspublication/ 2011/JC1853-GPP-Guidelines-2011-en.pdf. Accessed August 1, 2013.
    • (2011) Good Participatory Practice: Guidelines for Biomedical HIV Prevention Trials
  • 19
    • 77954076477 scopus 로고    scopus 로고
    • Community engagement and investment in biomedical HIV prevention research for youth: Rationale, challenges, and approaches
    • Ellen JM, Wallace M, Sawe FK, et al. Community engagement and investment in biomedical HIV prevention research for youth: rationale, challenges, and approaches. J Acquir Immune Defic Syndr. 2010;54:S7-S11.
    • (2010) J Acquir Immune Defic Syndr , vol.54
    • Ellen, J.M.1    Wallace, M.2    Sawe, F.K.3
  • 20
    • 33947420947 scopus 로고    scopus 로고
    • One step forward, two steps back - Requiring ministerial approval for all 'non-therapeutic' health research involving minors
    • Strode AE, Slack CM, Wassenaar DR, et al. One step forward, two steps back - requiring ministerial approval for all "non-therapeutic" health research involving minors. S Afr Med J. 2007;97: 200-202. (Pubitemid 46455886)
    • (2007) South African Medical Journal , vol.97 , Issue.3 , pp. 200-202
    • Strode, A.E.1    Slack, C.M.2    Wassenaar, D.R.3    Singh, J.A.4
  • 21
    • 84890944504 scopus 로고    scopus 로고
    • The search for minimal risk in international paediatric clinical trials
    • Accessed August 1, 2013
    • Evans Chan T. The search for minimal risk in international paediatric clinical trials, 5 Santa Clara J Int'l L. 2006. Available at: http:// digitalcommons.law.scu.edu/scujil/vol5/iss1/2. Accessed August 1, 2013.
    • (2006) 5 Santa Clara J Int'l L
    • Evans Chan, T.1
  • 22
    • 79959282779 scopus 로고    scopus 로고
    • Relative versus absolute standards for everyday risk in adolescent HIV prevention trials: Expanding the debate
    • Snyder J, Miller CL, Gray G. Relative versus absolute standards for everyday risk in adolescent HIV prevention trials: expanding the debate. Am J Bioeth. 2011;11: 5-13.
    • (2011) Am J Bioeth , vol.11 , pp. 5-13
    • Snyder, J.1    Miller, C.L.2    Gray, G.3
  • 23
    • 79959206940 scopus 로고    scopus 로고
    • Commentary: The dangers of using a relative standard for minimal risk
    • Shah S. Commentary: the dangers of using a relative standard for minimal risk. Am J Bioeth. 2011;11: 22-23.
    • (2011) Am J Bioeth , vol.11 , pp. 22-23
    • Shah, S.1
  • 25
    • 34249740611 scopus 로고    scopus 로고
    • Enrolling adolescents in HIV vaccine trials: Reflections on legal complexities from South Africa
    • Slack C, Strode A, Fleischer T, et al. Enrolling adolescents in HIV vaccine trials: reflections on legal complexities from South Africa. BMC Med Ethics. 2007;8:5.
    • (2007) BMC Med Ethics , vol.8 , pp. 5
    • Slack, C.1    Strode, A.2    Fleischer, T.3
  • 27
    • 84890940366 scopus 로고    scopus 로고
    • Towards a roadmap: Summary of identified ethical-legal complexities in adolescent HIV vaccine & microbicide research
    • Accessed January 2013
    • Essack Z, Slack C, Strode A. Towards a roadmap: summary of identified ethical-legal complexities in adolescent HIV vaccine & microbicide research. Global Campaign for Microbicides, 2008. Available at: http://www.global- campaign.org/clientfiles/Essack-Slack-Strode(2008) Towards-a-Roadmap.pdf. Accessed January 2013.
    • Global Campaign for Microbicides , vol.2008
    • Essack, Z.1    Slack, C.2    Strode, A.3
  • 28
    • 84878047118 scopus 로고    scopus 로고
    • Parents, adolescents, and consent for research participation
    • Iltis AS. Parents, adolescents, and consent for research participation. J Med Philos. 2013;38: 332-346.
    • (2013) J Med Philos , vol.38 , pp. 332-346
    • Iltis, A.S.1
  • 29
    • 4644281540 scopus 로고    scopus 로고
    • Interventions to improve research participants' understanding in informed consent for research: A systematic review
    • DOI 10.1001/jama.292.13.1593
    • Flory J, Emanuel E. Interventions to improve research participants understanding in informed consent for research: a systematic review. JAMA. 2004;292: 1593-1601. (Pubitemid 39314966)
    • (2004) Journal of the American Medical Association , vol.292 , Issue.13 , pp. 1593-1601
    • Flory, J.1    Emanuel, E.2
  • 30
  • 31
    • 0036695859 scopus 로고    scopus 로고
    • The ethics of paying for children's participation in research
    • Wendler D, Rackoff JE, Emanuel EJ, et al. The ethics of paying for children's participation in research. J Pediatr. 2002;141: 166-171.
    • (2002) J Pediatr , vol.141 , pp. 166-171
    • Wendler, D.1    Rackoff, J.E.2    Emanuel, E.J.3
  • 32
    • 84886290924 scopus 로고    scopus 로고
    • Misconceptions about coercion and undue influence: Reflections on the views of IRB members
    • Largent E, Grady C, Miller FG, et al. Misconceptions about coercion and undue influence: reflections on the views of IRB members. Bioethics. 2013;27: 500-507.
    • (2013) Bioethics , vol.27 , pp. 500-507
    • Largent, E.1    Grady, C.2    Miller, F.G.3
  • 33
    • 84873027435 scopus 로고    scopus 로고
    • The ancillary-care obligations of medical researchers working in developing countries
    • Participants in the 2006 Georgetown UniversityWorkshop on the Ancillary- Care Obligations of Medical Researchers Working in Developing Countries
    • Participants in the 2006 Georgetown UniversityWorkshop on the Ancillary- Care Obligations of Medical Researchers Working in Developing Countries. The ancillary-care obligations of medical researchers working in developing countries. PLoS Med. 2008;5:e90.
    • (2008) PLoS Med , vol.5
  • 34
    • 84872678512 scopus 로고    scopus 로고
    • Barriers to medication adherence in behaviorally and perinatally infected youth living with HIV
    • MacDonell K, Naar-King S, Huszti H, et al. Barriers to medication adherence in behaviorally and perinatally infected youth living with HIV. AIDS Behav. 2013;17: 86-93.
    • (2013) AIDS Behav , vol.17 , pp. 86-93
    • Macdonell, K.1    Naar-King, S.2    Huszti, H.3
  • 35
    • 84878958898 scopus 로고    scopus 로고
    • Pre-exposure prophylaxis for HIV in women: Daily oral tenofovir, oral tenofovir/emtricitabine, or vaginal tenofovir gel in the VOICE Study (MTN 003)
    • Paper presented, Atlanta, GA
    • Marrazzo J, Ramjee G, Nair G, et al. Pre-exposure prophylaxis for HIV in women: daily oral tenofovir, oral tenofovir/emtricitabine, or vaginal tenofovir gel in the VOICE Study (MTN 003). Paper presented at: Conference on Retroviruses and Opportunistic Infections; 2013; Atlanta, GA.
    • (2013) Conference on Retroviruses and Opportunistic Infections
    • Marrazzo, J.1    Ramjee, G.2    Nair, G.3
  • 37
    • 0028471768 scopus 로고
    • Reversing the presumption: The IOM report on women in health research
    • 121
    • Macklin R. Reversing the presumption: the IOM report on women in health research. J Am Med Womens Assoc. 1994;49:113-116, 121.
    • (1994) J Am Med Womens Assoc , vol.49 , pp. 113-116
    • Macklin, R.1
  • 38
    • 79957808796 scopus 로고    scopus 로고
    • Reframing the framework: Toward fair inclusion of pregnant women as participants in research
    • Lyerly AD, Little MO, Faden RR. Reframing the framework: toward fair inclusion of pregnant women as participants in research. Am J Bioeth. 2011;11: 50-52.
    • (2011) Am J Bioeth , vol.11 , pp. 50-52
    • Lyerly, A.D.1    Little, M.O.2    Faden, R.R.3
  • 39
    • 77954079088 scopus 로고    scopus 로고
    • Behavioral considerations for engaging youth in HIV clinical research
    • Hosek SG, Zimet GD. Behavioral considerations for engaging youth in HIV clinical research. J Acquir Immune Defic Syndr. 2010;54: S25-S30.
    • (2010) J Acquir Immune Defic Syndr , vol.54
    • Hosek, S.G.1    Zimet, G.D.2
  • 40
    • 77954064076 scopus 로고    scopus 로고
    • Youth-specific considerations in the development of pre-exposure prophylaxis, microbicide, and vaccine research trials
    • Rudy BJ, Kapogiannis BG, Lally MA, et al. Youth-specific considerations in the development of pre-exposure prophylaxis, microbicide, and vaccine research trials. J Acquir Immune Defic Syndr. 2010;54:S31-S42.
    • (2010) J Acquir Immune Defic Syndr , vol.54
    • Rudy, B.J.1    Kapogiannis, B.G.2    Lally, M.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.