-
1
-
-
84872967522
-
Cancer statistics, 2013
-
Siegel R, Naishadham D, Jemal A. Cancer statistics, 2013. CA Cancer J Clin. 2013;63(1):11-30.
-
(2013)
CA Cancer J Clin.
, vol.63
, Issue.1
, pp. 11-30
-
-
Siegel, R.1
Naishadham, D.2
Jemal, A.3
-
2
-
-
84873406234
-
Smoking status and survival in the National Comprehensive Cancer Network non-small cell lung cancer cohort
-
Ferketich AK, Niland JC, Mamet R, et al. Smoking status and survival in the National Comprehensive Cancer Network non-small cell lung cancer cohort. Cancer. 2013;119(4):847-853.
-
(2013)
Cancer.
, vol.119
, Issue.4
, pp. 847-853
-
-
Ferketich, A.K.1
Niland, J.C.2
Mamet, R.3
-
3
-
-
34548457234
-
The IASLC Lung Cancer Staging Project: Proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM Classification of malignant tumours
-
International Association for the Study of Lung Cancer International Staging Committee, Erratum appears in J Thorac Oncol. 2007;2(10):985
-
Goldstraw P, Crowley J, Chansky K, et al; International Association for the Study of Lung Cancer International Staging Committee. The IASLC Lung Cancer Staging Project: proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM Classification of malignant tumours [Erratum appears in J Thorac Oncol. 2007;2(10):985]. J Thorac Oncol. 2007;2(8):706-714.
-
(2007)
J Thorac Oncol.
, vol.2
, Issue.8
, pp. 706-714
-
-
Goldstraw, P.1
Crowley, J.2
Chansky, K.3
-
4
-
-
17844390172
-
Epidermal growth factor receptor mutations, smallmolecule kinase inhibitors, and non-small-cell lung cancer: Current knowledge and future directions
-
Pao W, Miller VA. Epidermal growth factor receptor mutations, smallmolecule kinase inhibitors, and non-small-cell lung cancer: current knowledge and future directions. J Clin Oncol. 2005;23(11):2556-2568.
-
(2005)
J Clin Oncol.
, vol.23
, Issue.11
, pp. 2556-2568
-
-
Pao, W.1
Miller, V.A.2
-
5
-
-
7144227965
-
Epidermal growth factor receptor (EGFR) and EGFR mutations, function and possible role in clinical trials
-
Voldborg BR, Damstrup L, Spang-Thomsen M, et al. Epidermal growth factor receptor (EGFR) and EGFR mutations, function and possible role in clinical trials. Ann Oncol. 1997;8(12):1197-1206.
-
(1997)
Ann Oncol.
, vol.8
, Issue.12
, pp. 1197-1206
-
-
Voldborg, B.R.1
Damstrup, L.2
Spang-Thomsen, M.3
-
6
-
-
80255135963
-
Epidermal growth factor receptor (EGFR) in lung cancer: An overview and update
-
Bethune G, Bethune D, Ridgway N, et al. Epidermal growth factor receptor (EGFR) in lung cancer: an overview and update. J Thorac Dis. 2010; 2(1):48-51.
-
(2010)
J Thorac Dis.
, vol.2
, Issue.1
, pp. 48-51
-
-
Bethune, G.1
Bethune, D.2
Ridgway, N.3
-
7
-
-
0027159063
-
Differential expression of the epidermal growth factor receptor and its ligands in primary non-small cell lung cancers and adjacent benign lung
-
Rusch V, Baselga J, Cordon-Cardo C, et al. Differential expression of the epidermal growth factor receptor and its ligands in primary non-small cell lung cancers and adjacent benign lung. Cancer Res. 1993;53(10 suppl): 2379-2385.
-
(1993)
Cancer Res.
, vol.53
, Issue.10 SUPPL.
, pp. 2379-2385
-
-
Rusch, V.1
Baselga, J.2
Cordon-Cardo, C.3
-
8
-
-
27544503230
-
Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small-cell lung cancer: Results from a randomised, placebo-controlled, multicentre study (Iressa Survival Evaluation in Lung Cancer)
-
Thatcher N, Chang A, Parikh P, et al. Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small-cell lung cancer: results from a randomised, placebo-controlled, multicentre study (Iressa Survival Evaluation in Lung Cancer). Lancet. 2005;366(9496): 1527-1537.
-
(2005)
Lancet.
, vol.366
, Issue.9496
, pp. 1527-1537
-
-
Thatcher, N.1
Chang, A.2
Parikh, P.3
-
9
-
-
0012381722
-
Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer (the IDEAL 1 Trial) [corrected]
-
Fukuoka M, Yano S, Giaccone G, et al. Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer (the IDEAL 1 Trial) [corrected]. J Clin Oncol. 2003;21(12):2237-2246.
-
(2003)
J Clin Oncol.
, vol.21
, Issue.12
, pp. 2237-2246
-
-
Fukuoka, M.1
Yano, S.2
Giaccone, G.3
-
10
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch TJ, Bell DW, Sordella R, et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med. 2004;350(21):2129-2139.
-
(2004)
N Engl J Med.
, vol.350
, Issue.21
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
-
11
-
-
2342624080
-
EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
Paez JG, Jänne PA, Lee JC, et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science. 2004;304 (5676):1497-1500.
-
(2004)
Science.
, vol.304
, Issue.5676
, pp. 1497-1500
-
-
Paez, J.G.1
Jänne, P.A.2
Lee, J.C.3
-
12
-
-
69949186250
-
Screening for epidermal growth factor receptor mutations in lung cancer
-
Spanish Lung Cancer Group
-
Rosell R, Moran T, Queralt C, et al; Spanish Lung Cancer Group. Screening for epidermal growth factor receptor mutations in lung cancer. N Engl J Med. 2009;361(10):958-967.
-
(2009)
N Engl J Med.
, vol.361
, Issue.10
, pp. 958-967
-
-
Rosell, R.1
Moran, T.2
Queralt, C.3
-
15
-
-
0142055937
-
Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: A randomized trial
-
Kris MG, Natale RB, Herbst RS, et al. Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: a randomized trial. JAMA. 2003;290(16):2149-2158.
-
(2003)
JAMA.
, vol.290
, Issue.16
, pp. 2149-2158
-
-
Kris, M.G.1
Natale, R.B.2
Herbst, R.S.3
-
16
-
-
22044445517
-
Erlotinib in previously treated non-small-cell lung cancer
-
Shepherd FA, Rodrigues Pereira J, Ciuleanu T, et al. Erlotinib in previously treated non-small-cell lung cancer. N Engl J Med. 2005;353(2): 123-132.
-
(2005)
N Engl J Med.
, vol.353
, Issue.2
, pp. 123-132
-
-
Shepherd, F.A.1
Rodrigues Pereira, J.2
Ciuleanu, T.3
-
17
-
-
69949162760
-
Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
-
Mok TS, Wu YL, Thongprasert S, et al. Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma. N Engl J Med. 2009;361(10):947-957.
-
(2009)
N Engl J Med.
, vol.361
, Issue.10
, pp. 947-957
-
-
Mok, T.S.1
Wu, Y.L.2
Thongprasert, S.3
-
18
-
-
84861976809
-
First-SIGNAL: First-line single-agent iressa versus gemcitabine and cisplatin trial in never-smokers with adenocarcinoma of the lung
-
Han JY, Park K, Kim SW, et al. First-SIGNAL: first-line single-agent iressa versus gemcitabine and cisplatin trial in never-smokers with adenocarcinoma of the lung. J Clin Oncol. 2012;30(10):1122-1128.
-
(2012)
J Clin Oncol.
, vol.30
, Issue.10
, pp. 1122-1128
-
-
Han, J.Y.1
Park, K.2
Kim, S.W.3
-
19
-
-
75249087060
-
Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): An open label, randomised phase 3 trial
-
Mitsudomi T, Morita S, Yatabe Y, et al. Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial. Lancet Oncol. 2010;11(2):121-128.
-
(2010)
Lancet Oncol.
, vol.11
, Issue.2
, pp. 121-128
-
-
Mitsudomi, T.1
Morita, S.2
Yatabe, Y.3
-
20
-
-
77953930730
-
Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR
-
Maemondo M, Inoue A, Kobayashi K, et al. Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR. N Engl J Med. 2010;362(25):2380-2388.
-
(2010)
N Engl J Med.
, vol.362
, Issue.25
, pp. 2380-2388
-
-
Maemondo, M.1
Inoue, A.2
Kobayashi, K.3
-
21
-
-
79960889662
-
Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive nonsmall-cell lung cancer (OPTIMAL, CTONG-0802): A multicentre, open-label, randomised, phase 3 study
-
Zhou C, Wu YL, Chen G, et al. Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive nonsmall-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study. Lancet Oncol. 2011;12(8):735-742.
-
(2011)
Lancet Oncol.
, vol.12
, Issue.8
, pp. 735-742
-
-
Zhou, C.1
Wu, Y.L.2
Chen, G.3
-
22
-
-
84857502654
-
Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutationpositive non-small-cell lung cancer (EURTAC): A multicentre, open-label, randomised phase 3 trial
-
Spanish Lung Cancer Group in collaboration with Groupe Français de Pneumo-Cancérologie and Associazione Italiana Oncologia Toracica
-
Rosell R, Carcereny E, Gervais R, et al; Spanish Lung Cancer Group in collaboration with Groupe Français de Pneumo-Cancérologie and Associazione Italiana Oncologia Toracica. Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutationpositive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial. Lancet Oncol. 2012;13(3):239-246.
-
(2012)
Lancet Oncol.
, vol.13
, Issue.3
, pp. 239-246
-
-
Rosell, R.1
Carcereny, E.2
Gervais, R.3
-
23
-
-
13844317894
-
EGFR mutation and resistance of non-small-cell lung cancer to gefitinib
-
Kobayashi S, Boggon TJ, Dayaram T, et al. EGFR mutation and resistance of non-small-cell lung cancer to gefitinib. N Engl J Med. 2005;352(8):786-792.
-
(2005)
N Engl J Med.
, vol.352
, Issue.8
, pp. 786-792
-
-
Kobayashi, S.1
Boggon, T.J.2
Dayaram, T.3
-
24
-
-
18244371651
-
Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain
-
Pao W, Miller VA, Politi KA, et al. Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain. PLoS Med. 2005;2(3):e73.
-
(2005)
PLoS Med.
, vol.2
, Issue.3
-
-
Pao, W.1
Miller, V.A.2
Politi, K.A.3
-
25
-
-
34249075147
-
MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling
-
Engelman JA, Zejnullahu K, Mitsudomi T, et al. MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling. Science. 2007;316(5827):1039-1043.
-
(2007)
Science.
, vol.316
, Issue.5827
, pp. 1039-1043
-
-
Engelman, J.A.1
Zejnullahu, K.2
Mitsudomi, T.3
-
26
-
-
84871597401
-
Updated overall survival results from a randomized phase III trial comparing gefitinib with carboplatin-paclitaxel for chemo-naive non-small cell lung cancer with sensitive EGFR gene mutations (NEJ002)
-
North-East Japan Study Group
-
Inoue A, Kobayashi K, Maemondo M, et al; North-East Japan Study Group. Updated overall survival results from a randomized phase III trial comparing gefitinib with carboplatin-paclitaxel for chemo-naive non-small cell lung cancer with sensitive EGFR gene mutations (NEJ002). Ann Oncol. 2013;24(1):54-59.
-
(2013)
Ann Oncol.
, vol.24
, Issue.1
, pp. 54-59
-
-
Inoue, A.1
Kobayashi, K.2
Maemondo, M.3
-
27
-
-
84863221857
-
Epidermal growth factor receptor-tyrosine kinase inhibitor therapy is effective as first-line treatment of advanced nonsmall-cell lung cancer with mutated EGFR: A meta-analysis from six phase III randomized controlled trials
-
Gao G, Ren S, Li A, et al. Epidermal growth factor receptor-tyrosine kinase inhibitor therapy is effective as first-line treatment of advanced nonsmall-cell lung cancer with mutated EGFR: a meta-analysis from six phase III randomized controlled trials. Int J Cancer. 2012;131(5):E822-E829.
-
(2012)
Int J Cancer.
, vol.131
, Issue.5
-
-
Gao, G.1
Ren, S.2
Li, A.3
-
28
-
-
84884736973
-
Phase III study of afatinib or cisplatin plus pemetrexed in patients with metastatic lung adenocarcinoma with EGFR mutations
-
Sequist LV, Yang JC, Yamamoto N, et al. Phase III study of afatinib or cisplatin plus pemetrexed in patients with metastatic lung adenocarcinoma with EGFR mutations. J Clin Oncol. 2013;31(27):3327-3334.
-
(2013)
J Clin Oncol.
, vol.31
, Issue.27
, pp. 3327-3334
-
-
Sequist, L.V.1
Yang, J.C.2
Yamamoto, N.3
-
29
-
-
84884659258
-
LUX-Lung 6: A randomized, open-label, phase III study of afatinib (A) versus gemcitabine/cisplatin (GC) as first-line treatment for Asian patients (pts) with EGFR mutation-positive (EGFR+) advanced adenocarcinoma of the lung
-
abstract 8016
-
Wu YL, Zhou C, Hu C-P, et al. LUX-Lung 6: a randomized, open-label, phase III study of afatinib (A) versus gemcitabine/cisplatin (GC) as first-line treatment for Asian patients (pts) with EGFR mutation-positive (EGFR+) advanced adenocarcinoma of the lung. J Clin Oncol. 2013;(31 suppl):abstract 8016.
-
(2013)
J Clin Oncol.
, Issue.31 SUPPL.
-
-
Wu, Y.L.1
Zhou, C.2
Hu, C.-P.3
-
30
-
-
84866655838
-
LUX-Lung 3: A randomized, open-label, phase III study of afatinib versus pemetrexed and cisplatin as first-line treatment for patients with advanced adenocarcinoma of the lung harboring EGFR-activating mutations
-
Yang JC-H, Schuler MH, Yamamoto N, et al. LUX-Lung 3: a randomized, open-label, phase III study of afatinib versus pemetrexed and cisplatin as first-line treatment for patients with advanced adenocarcinoma of the lung harboring EGFR-activating mutations. J Clin Oncol. 2012;39(18 suppl):LBA7500.
-
(2012)
J Clin Oncol.
, vol.39
, Issue.18 SUPPL.
-
-
Yang, J.C.-H.1
Schuler, M.H.2
Yamamoto, N.3
-
31
-
-
84890896341
-
Gefitinib versus placebo in completely resected non-small-cell lung cancer: Results of the NCIC CTG BR19 study
-
Goss GD, O'Callaghan C, Lorimer I, et al. Gefitinib versus placebo in completely resected non-small-cell lung cancer: results of the NCIC CTG BR19 study. J Clin Oncol. 2013;31(27):3320-3326.
-
(2013)
J Clin Oncol.
, vol.31
, Issue.27
, pp. 3320-3326
-
-
Goss, G.D.1
O'Callaghan, C.2
Lorimer, I.3
-
32
-
-
45149102984
-
Phase III trial of maintenance gefitinib or placebo after concurrent chemoradiotherapy and docetaxel consolidation in inoperable stage III non-small-cell lung cancer: SWOG S0023
-
Kelly K, Chansky K, Gaspar LE, et al. Phase III trial of maintenance gefitinib or placebo after concurrent chemoradiotherapy and docetaxel consolidation in inoperable stage III non-small-cell lung cancer: SWOG S0023. J Clin Oncol. 2008;26(15):2450-2456.
-
(2008)
J Clin Oncol.
, vol.26
, Issue.15
, pp. 2450-2456
-
-
Kelly, K.1
Chansky, K.2
Gaspar, L.E.3
-
33
-
-
84863011008
-
Survival benefit with erlotinib maintenance therapy in patients with advanced nonsmall-cell lung cancer (NSCLC) according to response to first-line chemotherapy
-
SATURN Investigators
-
Coudert B, Ciuleanu T, Park K, et al; SATURN Investigators. Survival benefit with erlotinib maintenance therapy in patients with advanced nonsmall-cell lung cancer (NSCLC) according to response to first-line chemotherapy. Ann Oncol. 2012;23(2):388-394.
-
(2012)
Ann Oncol.
, vol.23
, Issue.2
, pp. 388-394
-
-
Coudert, B.1
Ciuleanu, T.2
Park, K.3
-
34
-
-
21144439000
-
Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib
-
Kwak EL, Sordella R, Bell DW, et al. Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib. Proc Nat Acad Sci U S A. 2005;102(21):7665-7670.
-
(2005)
Proc Nat Acad Sci U S A.
, vol.102
, Issue.21
, pp. 7665-7670
-
-
Kwak, E.L.1
Sordella, R.2
Bell, D.W.3
-
35
-
-
84867406340
-
Combined therapy with mutant-selective EGFR inhibitor and Met kinase inhibitor for overcoming erlotinib resistance in EGFR-mutant lung cancer
-
Nakagawa T, Takeuchi S, Yamada T, et al. Combined therapy with mutant-selective EGFR inhibitor and Met kinase inhibitor for overcoming erlotinib resistance in EGFR-mutant lung cancer. Mol Cancer Ther. 2012;11(10):2149-2157.
-
(2012)
Mol Cancer Ther.
, vol.11
, Issue.10
, pp. 2149-2157
-
-
Nakagawa, T.1
Takeuchi, S.2
Yamada, T.3
-
36
-
-
84862777005
-
Correlation between MET gene copy number by silver in situ hybridization and protein expression by immunohistochemistry in non-small cell lung cancer
-
Dziadziuszko R, Wynes MW, Singh S, et al. Correlation between MET gene copy number by silver in situ hybridization and protein expression by immunohistochemistry in non-small cell lung cancer. J Thorac Oncol. 2012;7(2):340-347.
-
(2012)
J Thorac Oncol.
, vol.7
, Issue.2
, pp. 340-347
-
-
Dziadziuszko, R.1
Wynes, M.W.2
Singh, S.3
-
37
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011;144(5):646-674.
-
(2011)
Cell.
, vol.144
, Issue.5
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
38
-
-
0037050352
-
Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer
-
Eastern Cooperative Oncology Group
-
Schiller JH, Harrington D, Belani CP, et al; Eastern Cooperative Oncology Group. Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer. N Engl J Med. 2002;346(2):92-98.
-
(2002)
N Engl J Med.
, vol.346
, Issue.2
, pp. 92-98
-
-
Schiller, J.H.1
Harrington, D.2
Belani, C.P.3
-
39
-
-
0037050355
-
Lung cancer--time to move on from chemotherapy
-
Carney DN. Lung cancer--time to move on from chemotherapy. N Engl J Med. 2002;346(2):126-128.
-
(2002)
N Engl J Med.
, vol.346
, Issue.2
, pp. 126-128
-
-
Carney, D.N.1
|