Atropisomerization in N-aryl-2(1H)-pyrimidin-(thi)ones: A ring-opening/rotation/ring-closure process in place of a classical rotation around the pivot bond

Journal of Organic Chemistry

Volumn 78, Issue 24, 2013, Pages 12577-12584

  Najahi, Ennaji ^b   Vanthuyne, Nicolas ^a   Nepveu, Françoise ^b   Jean, Marion ^a   Alkorta, Ibon ^c   Elguero, Jose ^c   Roussel, Christian ^a  

^a AIX MARSEILLE UNIVERSITÉ   (France)

^b Hôpital Purpan   (France)

^c INSTITUTO DE QUÍMICA MÉDICA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CHIRAL SEPARATIONS; ENANTIOMERIZATION BARRIERS; PYRIMIDINETHIONES; RACEMIZATION PROCESS; ROTATIONAL BARRIERS; SEMI-PREPARATIVE HPLC; SULFUR DERIVATIVES; X-RAY DIFFRACTION STUDIES;

CHIRALITY; OXYGEN; SULFUR; X RAY DIFFRACTION;

ROTATION;

OXYGEN DERIVATIVE; PYRIMIDINONE DERIVATIVE; SULFUR DERIVATIVE;

ARTICLE; CHIRALITY; CYCLIZATION; ENANTIOMER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOMERIZATION; RACEMIZATION; RING CLOSING METATHESIS; RING OPENING; SYNTHESIS; X RAY DIFFRACTION;

CRYSTALLOGRAPHY, X-RAY; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PYRIMIDINES; QUANTUM THEORY; ROTATION; STEREOISOMERISM; THIONES;

EID: 84890904526     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo402149f     Document Type: Article

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