-
1
-
-
34250864795
-
Protein turnover via autophagy: implications for metabolism
-
Mizushima N., Klionsky D.J. Protein turnover via autophagy: implications for metabolism. Annu. Rev. Nutr. 2007, 19-40.
-
(2007)
Annu. Rev. Nutr.
, pp. 19-40
-
-
Mizushima, N.1
Klionsky, D.J.2
-
2
-
-
39849109338
-
Autophagy fights disease through cellular self-digestion
-
Mizushima N., et al. Autophagy fights disease through cellular self-digestion. Nature 2008, 451:1069-1075.
-
(2008)
Nature
, vol.451
, pp. 1069-1075
-
-
Mizushima, N.1
-
3
-
-
0036569331
-
Yeast autophagosomes: de novo formation of a membrane structure
-
Noda T., et al. Yeast autophagosomes: de novo formation of a membrane structure. Trends Cell Biol. 2002, 12:231-235.
-
(2002)
Trends Cell Biol.
, vol.12
, pp. 231-235
-
-
Noda, T.1
-
4
-
-
84855645313
-
Mechanisms of autophagosome biogenesis
-
Rubinsztein D.C., et al. Mechanisms of autophagosome biogenesis. Curr. Biol. 2012, 22:R29-R34.
-
(2012)
Curr. Biol.
, vol.22
-
-
Rubinsztein, D.C.1
-
5
-
-
84878562770
-
Autophagic processes in yeast: mechanism, machinery and regulation
-
Reggiori F., Klionsky D.J. Autophagic processes in yeast: mechanism, machinery and regulation. Genetics 2013, 194:341-361.
-
(2013)
Genetics
, vol.194
, pp. 341-361
-
-
Reggiori, F.1
Klionsky, D.J.2
-
6
-
-
77950465542
-
Current knowledge of the pre-autophagosomal structure (Pas)
-
Suzuki K., Ohsumi Y. Current knowledge of the pre-autophagosomal structure (Pas). FEBS Lett. 2010, 584:1280-1286.
-
(2010)
FEBS Lett.
, vol.584
, pp. 1280-1286
-
-
Suzuki, K.1
Ohsumi, Y.2
-
7
-
-
84875365804
-
Autophagosomes form at ER-mitochondria contact sites
-
Hamasaki M., et al. Autophagosomes form at ER-mitochondria contact sites. Nature 2013, 495:389-393.
-
(2013)
Nature
, vol.495
, pp. 389-393
-
-
Hamasaki, M.1
-
8
-
-
84881506338
-
The ER-Golgi intermediate compartment is a key membrane source for the Lc3 lipidation step of autophagosome biogenesis
-
Ge L., et al. The ER-Golgi intermediate compartment is a key membrane source for the Lc3 lipidation step of autophagosome biogenesis. eLife 2013, 2e00947.
-
(2013)
eLife
-
-
Ge, L.1
-
9
-
-
33846514235
-
Hierarchy of Atg proteins in pre-autophagosomal structure organization
-
Suzuki K., et al. Hierarchy of Atg proteins in pre-autophagosomal structure organization. Genes Cells 2007, 12:209-218.
-
(2007)
Genes Cells
, vol.12
, pp. 209-218
-
-
Suzuki, K.1
-
10
-
-
70349739560
-
Characterization of the Atg17-Atg29-Atg31 complex specifically required for starvation-induced autophagy in Saccharomyces cerevisiae
-
Kabeya Y., et al. Characterization of the Atg17-Atg29-Atg31 complex specifically required for starvation-induced autophagy in Saccharomyces cerevisiae. Biochem. Biophys. Res. Commun. 2009, 389:612-615.
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.389
, pp. 612-615
-
-
Kabeya, Y.1
-
11
-
-
79960585318
-
Ammonia-induced autophagy is independent of Ulk1/Ulk2 kinases
-
Cheong H., et al. Ammonia-induced autophagy is independent of Ulk1/Ulk2 kinases. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:11121-11126.
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, pp. 11121-11126
-
-
Cheong, H.1
-
12
-
-
84877323647
-
Regulation of nutrient-sensitive autophagy by uncoordinated 51-like kinases 1 and 2
-
Mcalpine F., et al. Regulation of nutrient-sensitive autophagy by uncoordinated 51-like kinases 1 and 2. Autophagy 2013, 9:361-373.
-
(2013)
Autophagy
, vol.9
, pp. 361-373
-
-
Mcalpine, F.1
-
13
-
-
43149090064
-
Fip200, a Ulk-interacting protein, is required for autophagosome formation in mammalian cells
-
Hara T., et al. Fip200, a Ulk-interacting protein, is required for autophagosome formation in mammalian cells. J. Cell Biol. 2008, 181:497-510.
-
(2008)
J. Cell Biol.
, vol.181
, pp. 497-510
-
-
Hara, T.1
-
14
-
-
66449083078
-
Ulk1-Atg13-Fip200 complex mediates mTOR signaling and is essential for autophagy
-
Ganley I.G., et al. Ulk1-Atg13-Fip200 complex mediates mTOR signaling and is essential for autophagy. J. Biol. Chem. 2009, 284:12297-12305.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 12297-12305
-
-
Ganley, I.G.1
-
15
-
-
65249119430
-
Nutrient-dependent mTORC1 association with the Ulk1-Atg13-Fip200 complex required for autophagy
-
Hosokawa N., et al. Nutrient-dependent mTORC1 association with the Ulk1-Atg13-Fip200 complex required for autophagy. Mol. Biol. Cell 2009, 20:1981-1991.
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 1981-1991
-
-
Hosokawa, N.1
-
16
-
-
65249176304
-
Ulk-Atg13-Fip200 complexes mediate mTOR signaling to the autophagy machinery
-
Jung C.H., et al. Ulk-Atg13-Fip200 complexes mediate mTOR signaling to the autophagy machinery. Mol. Biol. Cell 2009, 20:1992-2003.
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 1992-2003
-
-
Jung, C.H.1
-
17
-
-
67549110195
-
A novel, human Atg13 binding protein, Atg101, interacts with Ulk1 and is essential for macroautophagy
-
Mercer C.A., et al. A novel, human Atg13 binding protein, Atg101, interacts with Ulk1 and is essential for macroautophagy. Autophagy 2009, 5:649-662.
-
(2009)
Autophagy
, vol.5
, pp. 649-662
-
-
Mercer, C.A.1
-
18
-
-
58149473473
-
Kinase-inactivated Ulk proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanism
-
Chan E.Y., et al. Kinase-inactivated Ulk proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanism. Mol. Cell. Biol. 2009, 29:157-171.
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 157-171
-
-
Chan, E.Y.1
-
19
-
-
77957198526
-
An Atg9-containing compartment that functions in the early steps of autophagosome biogenesis
-
Mari M., et al. An Atg9-containing compartment that functions in the early steps of autophagosome biogenesis. J. Cell Biol. 2010, 190:1005-1022.
-
(2010)
J. Cell Biol.
, vol.190
, pp. 1005-1022
-
-
Mari, M.1
-
20
-
-
78649682788
-
Membrane delivery to the yeast autophagosome from the Golgi-endosomal system
-
Ohashi Y., Munro S. Membrane delivery to the yeast autophagosome from the Golgi-endosomal system. Mol. Biol. Cell 2010, 21:3998-4008.
-
(2010)
Mol. Biol. Cell
, vol.21
, pp. 3998-4008
-
-
Ohashi, Y.1
Munro, S.2
-
21
-
-
84864991509
-
Atg9 vesicles are an important membrane source during early steps of autophagosome formation
-
Yamamoto H., et al. Atg9 vesicles are an important membrane source during early steps of autophagosome formation. J. Cell Biol. 2012, 198:219-233.
-
(2012)
J. Cell Biol.
, vol.198
, pp. 219-233
-
-
Yamamoto, H.1
-
22
-
-
33750366092
-
Starvation and Ulk1-dependent cycling of mammalian Atg9 between the TGN and endosomes
-
Young A.R.J., et al. Starvation and Ulk1-dependent cycling of mammalian Atg9 between the TGN and endosomes. J. Cell Sci. 2006, 119:3888-3900.
-
(2006)
J. Cell Sci.
, vol.119
, pp. 3888-3900
-
-
Young, A.R.J.1
-
23
-
-
84861158462
-
Dynamic and transient interactions of Atg9 with autophagosomes, but not membrane integration, are required for autophagy
-
Orsi A., et al. Dynamic and transient interactions of Atg9 with autophagosomes, but not membrane integration, are required for autophagy. Mol. Biol. Cell 2012, 23:1860-1873.
-
(2012)
Mol. Biol. Cell
, vol.23
, pp. 1860-1873
-
-
Orsi, A.1
-
24
-
-
0346503885
-
The Atg1-Atg13 complex regulates Atg9 and Atg23 retrieval transport from the pre-autophagosomal structure
-
Reggiori F., et al. The Atg1-Atg13 complex regulates Atg9 and Atg23 retrieval transport from the pre-autophagosomal structure. Dev. Cell 2004, 6:79-90.
-
(2004)
Dev. Cell
, vol.6
, pp. 79-90
-
-
Reggiori, F.1
-
25
-
-
0347611578
-
Atg23 is essential for the Cvt pathway and efficient autophagy but not pexophagy
-
Tucker K.A., et al. Atg23 is essential for the Cvt pathway and efficient autophagy but not pexophagy. J. Biol. Chem. 2003, 278:48445-48452.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 48445-48452
-
-
Tucker, K.A.1
-
26
-
-
33846807374
-
Atg27 is required for autophagy-dependent cycling of Atg9
-
Yen W-L., et al. Atg27 is required for autophagy-dependent cycling of Atg9. Mol. Biol. Cell 2007, 18:581-593.
-
(2007)
Mol. Biol. Cell
, vol.18
, pp. 581-593
-
-
Yen, W.-L.1
-
27
-
-
77954184503
-
Post-Golgi Sec proteins are required for autophagy in Saccharomyces cerevisiae
-
Geng J.F., et al. Post-Golgi Sec proteins are required for autophagy in Saccharomyces cerevisiae. Mol. Biol. Cell 2010, 21:2257-2269.
-
(2010)
Mol. Biol. Cell
, vol.21
, pp. 2257-2269
-
-
Geng, J.F.1
-
28
-
-
34347250847
-
Crystal structure of the Sec4p-Sec2p complex in the nucleotide exchanging intermediate state
-
Sato Y., et al. Crystal structure of the Sec4p-Sec2p complex in the nucleotide exchanging intermediate state. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:8305-8310.
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 8305-8310
-
-
Sato, Y.1
-
29
-
-
78651488777
-
Ralb and the exocyst mediate the cellular starvation response by direct activation of autophagosome assembly
-
Bodemann B.O., et al. Ralb and the exocyst mediate the cellular starvation response by direct activation of autophagosome assembly. Cell 2011, 144:253-267.
-
(2011)
Cell
, vol.144
, pp. 253-267
-
-
Bodemann, B.O.1
-
30
-
-
84871581862
-
Architecture of the Atg17 complex as a scaffold for autophagosome biogenesis
-
Ragusa M.J., et al. Architecture of the Atg17 complex as a scaffold for autophagosome biogenesis. Cell 2012, 151:1501-1512.
-
(2012)
Cell
, vol.151
, pp. 1501-1512
-
-
Ragusa, M.J.1
-
31
-
-
0034682772
-
Apg13p and Vac8p are part of a complex of phosphoproteins that are required for cytoplasm to vacuole targeting
-
Scott S.V., et al. Apg13p and Vac8p are part of a complex of phosphoproteins that are required for cytoplasm to vacuole targeting. J. Biol. Chem. 2000, 275:25840-25849.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 25840-25849
-
-
Scott, S.V.1
-
32
-
-
0034683568
-
TOR-mediated induction of autophagy via an Apg1 protein kinase complex
-
Kamada Y., et al. TOR-mediated induction of autophagy via an Apg1 protein kinase complex. J. Cell Biol. 2000, 150:1507-1513.
-
(2000)
J. Cell Biol.
, vol.150
, pp. 1507-1513
-
-
Kamada, Y.1
-
33
-
-
70350128436
-
The TOR and PKA signaling pathways independently target the Atg1/Atg13 protein kinase complex to control autophagy
-
Stephan J.S., et al. The TOR and PKA signaling pathways independently target the Atg1/Atg13 protein kinase complex to control autophagy. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:17049-17054.
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 17049-17054
-
-
Stephan, J.S.1
-
34
-
-
75749090429
-
TOR directly controls the Atg1 kinase complex to regulate autophagy
-
Kamada Y., et al. TOR directly controls the Atg1 kinase complex to regulate autophagy. Mol. Cell. Biol. 2010, 30:1049-1058.
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 1049-1058
-
-
Kamada, Y.1
-
35
-
-
84866426794
-
Binding of the Atg1/Ulk1 kinase to the ubiquitin-like protein Atg8 regulates autophagy
-
Kraft C., et al. Binding of the Atg1/Ulk1 kinase to the ubiquitin-like protein Atg8 regulates autophagy. EMBO J. 2012, 31:3691-3703.
-
(2012)
EMBO J.
, vol.31
, pp. 3691-3703
-
-
Kraft, C.1
-
36
-
-
39449108917
-
The Atg1 kinase complex is involved in the regulation of protein recruitment to initiate sequestering vesicle formation for nonspecific autophagy in Saccharomyces cerevisiae
-
Cheong H., et al. The Atg1 kinase complex is involved in the regulation of protein recruitment to initiate sequestering vesicle formation for nonspecific autophagy in Saccharomyces cerevisiae. Mol. Biol. Cell 2008, 19:668-681.
-
(2008)
Mol. Biol. Cell
, vol.19
, pp. 668-681
-
-
Cheong, H.1
-
37
-
-
65449186232
-
Atg17 recruits Atg9 to organize the pre-autophogsomal structure
-
Sekito T., et al. Atg17 recruits Atg9 to organize the pre-autophogsomal structure. Genes Cells 2009, 14:525-538.
-
(2009)
Genes Cells
, vol.14
, pp. 525-538
-
-
Sekito, T.1
-
38
-
-
34247623568
-
Coats, tethers, Rabs, and SNARES work together to mediate the intracellular destination of a transport vesicle
-
Cai H.Q., et al. Coats, tethers, Rabs, and SNARES work together to mediate the intracellular destination of a transport vesicle. Dev. Cell 2007, 12:671-682.
-
(2007)
Dev. Cell
, vol.12
, pp. 671-682
-
-
Cai, H.Q.1
-
39
-
-
56149091013
-
The TRAPP complex: insights into its architecture and function
-
Sacher M., et al. The TRAPP complex: insights into its architecture and function. Traffic 2008, 9:2032-2042.
-
(2008)
Traffic
, vol.9
, pp. 2032-2042
-
-
Sacher, M.1
-
40
-
-
84860797387
-
Regulation of selective autophagy onset by a Ypt/Rab GTPase module
-
Lipatova Z., et al. Regulation of selective autophagy onset by a Ypt/Rab GTPase module. Proc. Natl. Acad. Sci. U.S.A. 2012, 109:6981-6986.
-
(2012)
Proc. Natl. Acad. Sci. U.S.A.
, vol.109
, pp. 6981-6986
-
-
Lipatova, Z.1
-
41
-
-
77952329475
-
Trs85 directs a Ypt1 GEF, TRAPPIII, to the phagophore to promote autophagy
-
Lynch-Day M.A., et al. Trs85 directs a Ypt1 GEF, TRAPPIII, to the phagophore to promote autophagy. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:7811-7816.
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 7811-7816
-
-
Lynch-Day, M.A.1
-
42
-
-
25844489089
-
Trs85 (Gsg1), a component of the TRAPP complexes, is required for the organization of the preautophagosomal structure during selective autophagy via the Cvt pathway
-
Meiling-Wesse K., et al. Trs85 (Gsg1), a component of the TRAPP complexes, is required for the organization of the preautophagosomal structure during selective autophagy via the Cvt pathway. J. Biol. Chem. 2005, 280:33669-33678.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 33669-33678
-
-
Meiling-Wesse, K.1
-
43
-
-
33845345128
-
Trs85 is required for macroautophagy, pexophagy and cytoplasm to vacuole targeting in Yarrowia lipolytica and Saccharomyces cerevisiae
-
Nazarko T.Y., et al. Trs85 is required for macroautophagy, pexophagy and cytoplasm to vacuole targeting in Yarrowia lipolytica and Saccharomyces cerevisiae. Autophagy 2005, 1:37-45.
-
(2005)
Autophagy
, vol.1
, pp. 37-45
-
-
Nazarko, T.Y.1
-
44
-
-
84862552255
-
Modular TRAPP complexes regulate intracellular protein trafficking through multiple Ypt/Rab GTPases in Saccharomyces cerevisiae
-
Zou S.S., et al. Modular TRAPP complexes regulate intracellular protein trafficking through multiple Ypt/Rab GTPases in Saccharomyces cerevisiae. Genetics 2012, 191:451-460.
-
(2012)
Genetics
, vol.191
, pp. 451-460
-
-
Zou, S.S.1
-
45
-
-
84871811752
-
Atg9 vesicles recruit vesicle-tethering proteins Trs85 and Ypt1 to the autophagosome formation site
-
Kakuta S., et al. Atg9 vesicles recruit vesicle-tethering proteins Trs85 and Ypt1 to the autophagosome formation site. J. Biol. Chem. 2012, 287:44261-44269.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 44261-44269
-
-
Kakuta, S.1
-
46
-
-
84878983074
-
Ypt1 recruits the Atg1 kinase to the preautophagosomal structure
-
Wang J., et al. Ypt1 recruits the Atg1 kinase to the preautophagosomal structure. Proc. Natl. Acad. Sci. U. S. A. 2013, 110:9800-9805.
-
(2013)
Proc. Natl. Acad. Sci. U. S. A.
, vol.110
, pp. 9800-9805
-
-
Wang, J.1
-
47
-
-
78149306025
-
Multisubunit tethering complexes and their role in membrane fusion
-
Brocker C., et al. Multisubunit tethering complexes and their role in membrane fusion. Curr. Biol. 2010, 20:R943-R952.
-
(2010)
Curr. Biol.
, vol.20
-
-
Brocker, C.1
-
48
-
-
79960774898
-
Autophagosome precursor maturation requires homotypic fusion
-
Moreau K., et al. Autophagosome precursor maturation requires homotypic fusion. Cell 2011, 146:303-317.
-
(2011)
Cell
, vol.146
, pp. 303-317
-
-
Moreau, K.1
-
49
-
-
84872793852
-
Connections between SNARES and autophagy
-
Moreau K., et al. Connections between SNARES and autophagy. Trends Biochem. Sci. 2013, 38:57-63.
-
(2013)
Trends Biochem. Sci.
, vol.38
, pp. 57-63
-
-
Moreau, K.1
-
50
-
-
79960798816
-
SNARE proteins are required for macroautophagy
-
Nair U., et al. SNARE proteins are required for macroautophagy. Cell 2011, 146:290-302.
-
(2011)
Cell
, vol.146
, pp. 290-302
-
-
Nair, U.1
-
51
-
-
58849092285
-
Membrane fusion: grappling with SNARE and SM proteins
-
Sudhof T.C., Rothman J.E. Membrane fusion: grappling with SNARE and SM proteins. Science 2009, 323:474-477.
-
(2009)
Science
, vol.323
, pp. 474-477
-
-
Sudhof, T.C.1
Rothman, J.E.2
-
52
-
-
84875834380
-
A HORMA domain in Atg13 mediates PI 3-kinase recruitment in autophagy
-
Jao C.C., et al. A HORMA domain in Atg13 mediates PI 3-kinase recruitment in autophagy. Proc. Natl. Acad. Sci. U.S.A. 2013, 110:5486-5491.
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 5486-5491
-
-
Jao, C.C.1
-
53
-
-
84880019176
-
Fine mapping of autophagy-related proteins during autophagosome formation in Saccharomyces cerevisiae
-
Suzuki K., et al. Fine mapping of autophagy-related proteins during autophagosome formation in Saccharomyces cerevisiae. J. Cell Sci. 2013, 126:2534-2544.
-
(2013)
J. Cell Sci.
, vol.126
, pp. 2534-2544
-
-
Suzuki, K.1
-
54
-
-
84865251228
-
The autophagy-related protein kinase Atg1 interacts with the ubiquitin-like protein Atg8 via the Atg8 family interacting motif to facilitate autophagosome formation
-
Nakatogawa H., et al. The autophagy-related protein kinase Atg1 interacts with the ubiquitin-like protein Atg8 via the Atg8 family interacting motif to facilitate autophagosome formation. J. Biol. Chem. 2012, 287:28503-28507.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 28503-28507
-
-
Nakatogawa, H.1
-
55
-
-
84869222326
-
Atg8 family proteins act as scaffolds for assembly of the Ulk complex sequence requirements for Lc3-interacting region (LIR) motifs
-
Alemu E.A., et al. Atg8 family proteins act as scaffolds for assembly of the Ulk complex sequence requirements for Lc3-interacting region (LIR) motifs. J. Biol. Chem. 2012, 287:39275-39290.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 39275-39290
-
-
Alemu, E.A.1
-
56
-
-
78649299852
-
Activation of Atg1 kinase in autophagy by regulated phosphorylation
-
Kijanska M., et al. Activation of Atg1 kinase in autophagy by regulated phosphorylation. Autophagy 2010, 6:1168-1178.
-
(2010)
Autophagy
, vol.6
, pp. 1168-1178
-
-
Kijanska, M.1
-
57
-
-
84869040414
-
Curvature, lipid packing, and electrostatics of membrane organelles: defining cellular territories in determining specificity
-
Bigay J., Antonny B. Curvature, lipid packing, and electrostatics of membrane organelles: defining cellular territories in determining specificity. Dev. Cell 2012, 23:886-895.
-
(2012)
Dev. Cell
, vol.23
, pp. 886-895
-
-
Bigay, J.1
Antonny, B.2
|