Effects of through-hole drug reservoirs on key clinical attributes for drug-eluting depot stent

Medical Engineering and Physics

Volumn 35, Issue 7, 2013, Pages 884-897

  Hsiao, Hao Ming ^a   Chiu, Yi Hsiang ^a   Wu, Tsung Yuan ^a   Shen, Jung Keng ^a   Lee, Ting Yu ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Depot stent; Drug eluting stent; Finite element; Radial strength; Reservoir shape; Stent fatigue life

Indexed keywords

ARTIFICIAL ORGANS; DISEASES; ECONOMIC AND SOCIAL EFFECTS; FATIGUE OF MATERIALS; FINITE ELEMENT METHOD; SAFETY FACTOR; SCAFFOLDS;

BALLOON EXPANDABLE STENT; CORONARY ARTERY DISEASE; DEPOT STENT; DRUG LOADING CAPACITY; DRUG-ELUTING STENTS; EQUIVALENT PLASTIC STRAIN; RADIAL STRENGTH; SMART DRUG DELIVERIES;

STENTS;

ARTICLE; BIOMECHANICS; CONTROLLED STUDY; DEVICE SAFETY; DRUG DELIVERY SYSTEM; DRUG ELUTING STENT; FINITE ELEMENT ANALYSIS; GEOMETRY; MATERIALS TESTING; PARTICLE SIZE; PRIORITY JOURNAL; SURFACE PROPERTY; TENSILE STRENGTH;

EID: 84890858276     PISSN: 13504533     EISSN: 18734030     Source Type: Journal    
DOI: 10.1016/j.medengphy.2012.08.021     Document Type: Article

References (21)

1. Bell MR, Berger PB, Bresnahan JF, Reeder GS, Bailey KR, Holmes DR. Initial and long-term outcome of 354 patients after coronary balloon angioplasty of total coronary-artery occlusions. Circulation 1992;85:1003-11.
2. Landau C, Lange RA, Hillis LD. Medical progress-percutaneous transluminal coronary angioplasty. N Engl J Med 1994;330:981-93.
3. van der Hoeven BL, Pires NMM, Warda HM, Oemrawsingh PV, van Vlijmen BJM, Quax PHA, et al. Drug-eluting stents: results, promises and problems. Int J Cardiol 2005;99:9-17.
4. Morice M, Serruys PW, Sousa JE, Fajadet J, Hayashi EB, Perin M, et al. A randomized comparison of a sirolimus-eluting stent with a standard stent for coronary revascularization. N Engl J Med 2002;346:1773-80.
5. Moses JW, Leon MB, Popma JJ, Fitzgerald PJ, Holmes DR, O'Shaughnessy C, et al. Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery. N Engl J Med 2003;349:1315-23.
6. Finkelstein A, McClean D, Kar S, Takizawa K, Varghese K, Baek N, et al. Local drug delivery via a coronary stent with programmable release pharmacokinetics. Circulation 2003;107:777-84.
7. Serruys PW, Sianos G, Abizaid A, Aoki J, den Heijer P, Bonnier H, et al. The effect of variable dose and release kinetics on neointimal hyperplasia using a novel paclitaxel-eluting stent platform-the paclitaxel in-stent controlled elution study (PISCES). J Am Coll Cardiol 2005;46:253-60.
8. Dumoulin C, Cochelin B. Mechanical behaviour modelling of balloonexpandable stents. J Biomech 2000;33:1461-70.
9. Migliavacca F, Petrini L, Montanari V, Quagliana I, Auricchio F, Dubini G. A predictive study of the mechanical behaviour of coronary stents by computer modelling. Med Eng Phys 2005;27:13-8.
10. Migliavacca F, Gervasco F, Prosi M, Zunino P, Minisini S, Formaggia L, et al. Expansion and drug elution model of a coronary stent. Comput Methods Biomech Biomed Eng 2007;10:63-73.
11. Donnelly EW, Bruzzi MS, Connolley T, McHugh PE. Finite element comparison of performance related characteristics of balloon expandable stents. Comput Methods Biomech Biomed Eng 2007;10:103-10.
12. Gervaso F, Capelli C, Petrini L, Lattanzio S, Di Virgilio L, Migliavacca F. On the effects of different strategies in modelling balloon-expandable stenting by means of finite element method. J Biomech 2008;41:1206-12.
13. Early M, Lally C, Prendergast PJ, Kelly DJ. Stresses in peripheral arteries following stent placement: a finite element analysis. Comput Methods Biomech Biomed Eng 2009;12:25-33.
14. Hsiao HM, Nikanorov A, Prabhu S, Razavi MK. Respiration-induced kidney motion on cobalt-chromium stent fatigue resistance. J Biomed Mater Res B 2009;91:508-16.
15. Hsiao HM. Why similar stent designs cause new clinical issues? J Am Coll Cardiol Interv 2012;5:362-3.
16. Hsiao HM, Chiu YH, Lee KH, Lin CH. Computational modeling of effects of intravascular stent design on key mechanical and hemodynamic behavior. Comput Aided Des 2012;44:757-65.
17. Hsiao HM, Lee KH, Liao YC, Cheng YC. Cardiovascular stent design and wall shear stress distribution in coronary stented arteries. Micro Nano Lett 2012;7: 430-3.
18. Gizdulich P, Wesseling KH. Forearm arterial pressure-volume relationships in man. Clin Phys Physiol Meas 1988;9:123-32.
19. Muntinga JHJ, van Leeuwen JTM, Gels ME, Terpstra WF, Smit AJ, Visser KR. Arteriolar constriction in mild-to-moderate essential hypertension: an old concept requiring reconsideration? J Hypertens 1997;15: 411-9.
20. Suresh S. Fatigue of materials. Cambridge, UK: Cambridge University Press; 1991.
21. Hsiao HM, Prabhu S, Nikanorov A. Renal artery stent bending fatigue analysis. ASME J Med Dev 2007;1:113-8.