Hyperoxia inhibits glucose-induced insulin secretion and mitochondrial metabolism in rat pancreatic islets

Biochemical and Biophysical Research Communications

Volumn 443, Issue 1, 2014, Pages 223-228

  Ma, Zuheng ^a   Moruzzi, Noah ^a   Catrina, Sergiu Bogdan ^a   Grill, Valdemar ^a,b,c   Björklund, Anneli ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

^c TRONDHEIM UNIVERSITY HOSPITAL   (Norway)

Author keywords

Hyperoxia; Insulin biosynthesis; Insulin secretion

Indexed keywords

CYTOCHROME C OXIDASE; GLUCOSE; IMMUNOREACTIVE INSULIN; OLIGOMYCIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); UBIQUINOL CYTOCHROME C REDUCTASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CIRCULATION; CONTROLLED STUDY; HYPEROXIA; HYPOXIA; IN VITRO STUDY; INSULIN RELEASE; INSULIN SYNTHESIS; MALE; MITOCHONDRIAL RESPIRATION; NECROSIS; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXYGENATION; PANCREAS ISLET; PRIORITY JOURNAL; PROTEIN CONTENT; RAT; SPRAGUE DAWLEY RAT; WESTERN BLOTTING;

RATTUS;

HYPEROXIA; INSULIN BIOSYNTHESIS; INSULIN SECRETION;

ANIMALS; APOPTOSIS; CELL SEPARATION; DNA; ELECTRON TRANSPORT CHAIN COMPLEX PROTEINS; GLUCOSE; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INSULIN; INSULIN-SECRETING CELLS; MALE; MITOCHONDRIA; OXIDATIVE PHOSPHORYLATION; OXYGEN; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES;

EID: 84890858270     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.11.088     Document Type: Article

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