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Volumn 63, Issue , 2014, Pages 85-91

Behavioral therapy reverses circadian deficits in a transgenic mouse model of Huntington's disease

Author keywords

Alzheimer's disease; Bright light therapy; Circadian; Exercise; Sleep

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR THERAPY; CAUSE OF DEATH; CIRCADIAN RHYTHM; CIRCADIAN RHYTHM SLEEP DISORDER; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENOTYPE; HUNTINGTON CHOREA; IN VIVO STUDY; LIGHT DARK CYCLE; MALE; MOUSE; NONHUMAN; PHOTOTHERAPY; PRIORITY JOURNAL; SLEEP WALKING; SUPRACHIASMATIC NUCLEUS; TRANSGENIC MOUSE;

EID: 84890847943     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2013.11.008     Document Type: Article
Times cited : (41)

References (59)
  • 1
    • 33846859816 scopus 로고    scopus 로고
    • Exercise as a synchroniser of human circadian rhythms: an update and discussion of the methodological problems
    • Atkinson G., et al. Exercise as a synchroniser of human circadian rhythms: an update and discussion of the methodological problems. Eur. J. Appl. Physiol. 2007, 99:331-341.
    • (2007) Eur. J. Appl. Physiol. , vol.99 , pp. 331-341
    • Atkinson, G.1
  • 2
    • 67149136453 scopus 로고    scopus 로고
    • Weight loss in neurodegenerative disorders
    • Aziz N.A., et al. Weight loss in neurodegenerative disorders. J. Neurol. 2008, 255:1872-1880.
    • (2008) J. Neurol. , vol.255 , pp. 1872-1880
    • Aziz, N.A.1
  • 3
    • 71849115710 scopus 로고    scopus 로고
    • Delayed onset of the diurnal melatonin rise in patients with Huntington's disease
    • Aziz N.A., et al. Delayed onset of the diurnal melatonin rise in patients with Huntington's disease. J. Neurol. 2009, 256:1961-1965.
    • (2009) J. Neurol. , vol.256 , pp. 1961-1965
    • Aziz, N.A.1
  • 5
    • 70349299834 scopus 로고    scopus 로고
    • Increased numbers of motor activity peaks during light cycle are associated with reductions in adrenergic α2-receptor levels in a transgenic Huntington's disease rat model
    • Bode F.J., et al. Increased numbers of motor activity peaks during light cycle are associated with reductions in adrenergic α2-receptor levels in a transgenic Huntington's disease rat model. Behav. Brain Res. 2009, 205:175-182.
    • (2009) Behav. Brain Res. , vol.205 , pp. 175-182
    • Bode, F.J.1
  • 6
    • 0036338822 scopus 로고    scopus 로고
    • Biologic rhythms and Parkinson's disease: a chronopharmacologic approach to considering fluctuations in function
    • Bruguerolle B., Simon N. Biologic rhythms and Parkinson's disease: a chronopharmacologic approach to considering fluctuations in function. Clin. Neuropharmacol. 2002, 25:194-201.
    • (2002) Clin. Neuropharmacol. , vol.25 , pp. 194-201
    • Bruguerolle, B.1    Simon, N.2
  • 7
    • 0037342965 scopus 로고    scopus 로고
    • Exercise elicits phase shifts and acute alterations of melatonin that vary with circadian phase
    • Buxton O.M., et al. Exercise elicits phase shifts and acute alterations of melatonin that vary with circadian phase. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2003, 284:R714-R724.
    • (2003) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.284
    • Buxton, O.M.1
  • 8
    • 79551593475 scopus 로고    scopus 로고
    • Exercise for the treatment of depression and anxiety
    • Carek P.J., et al. Exercise for the treatment of depression and anxiety. Int. J. Psychiatry Med. 2011, 41:15-28.
    • (2011) Int. J. Psychiatry Med. , vol.41 , pp. 15-28
    • Carek, P.J.1
  • 9
    • 0033560924 scopus 로고    scopus 로고
    • Characterization of progressive motor deficits in mice transgenic for the human Huntington's disease mutation
    • Carter R.J., et al. Characterization of progressive motor deficits in mice transgenic for the human Huntington's disease mutation. J. Neurosci. 1999, 19:3248-3257.
    • (1999) J. Neurosci. , vol.19 , pp. 3248-3257
    • Carter, R.J.1
  • 10
    • 69849105296 scopus 로고    scopus 로고
    • Neurogenetics of food anticipation
    • Challet E., et al. Neurogenetics of food anticipation. Eur. J. Neurosci. 2009, 30:1676-1687.
    • (2009) Eur. J. Neurosci. , vol.30 , pp. 1676-1687
    • Challet, E.1
  • 11
    • 41649085452 scopus 로고    scopus 로고
    • Rigidity in social and emotional memory in the R6/2 mouse model of Huntington's disease
    • Ciamei A., Morton A.J. Rigidity in social and emotional memory in the R6/2 mouse model of Huntington's disease. Neurobiol. Learn. Mem. 2008, 89:533-544.
    • (2008) Neurobiol. Learn. Mem. , vol.89 , pp. 533-544
    • Ciamei, A.1    Morton, A.J.2
  • 12
    • 33748441730 scopus 로고    scopus 로고
    • Sleep disorders in psychiatry
    • Costa e Silva J.A. Sleep disorders in psychiatry. Metabolism 2006, 55:S40-S44.
    • (2006) Metabolism , vol.55
    • Costa e Silva, J.A.1
  • 13
    • 41349122663 scopus 로고    scopus 로고
    • Serotonergic activation potentiates light resetting of the main circadian clock and alters clock gene expression in a diurnal rodent
    • Cuesta M., et al. Serotonergic activation potentiates light resetting of the main circadian clock and alters clock gene expression in a diurnal rodent. Exp. Neurol. 2008, 210:501-513.
    • (2008) Exp. Neurol. , vol.210 , pp. 501-513
    • Cuesta, M.1
  • 14
    • 81955167992 scopus 로고    scopus 로고
    • The methamphetamine-sensitive circadian oscillator is dysfunctional in a transgenic mouse model of Huntington's disease
    • Cuesta M., et al. The methamphetamine-sensitive circadian oscillator is dysfunctional in a transgenic mouse model of Huntington's disease. Neurobiol. Dis. 2012, 45:145-155.
    • (2012) Neurobiol. Dis. , vol.45 , pp. 145-155
    • Cuesta, M.1
  • 15
    • 0029937519 scopus 로고    scopus 로고
    • Phase-shifting effect of 8-OH-DPAT, a 5-HT1A/5-HT7 receptor agonist, on locomotor activity in golden hamster in constant darkness
    • Cutrera R.A., et al. Phase-shifting effect of 8-OH-DPAT, a 5-HT1A/5-HT7 receptor agonist, on locomotor activity in golden hamster in constant darkness. Neurosci. Lett. 1996, 210:1-4.
    • (1996) Neurosci. Lett. , vol.210 , pp. 1-4
    • Cutrera, R.A.1
  • 16
    • 35648958264 scopus 로고    scopus 로고
    • Light treatment for neuropsychiatric behaviors in Alzheimer's disease
    • Dowling G.A., et al. Light treatment for neuropsychiatric behaviors in Alzheimer's disease. West. J. Nurs. Res. 2007, 29:961-975.
    • (2007) West. J. Nurs. Res. , vol.29 , pp. 961-975
    • Dowling, G.A.1
  • 17
    • 0029586346 scopus 로고
    • Phase-shifting human circadian rhythms with exercise during the night shift
    • Eastman C.I., et al. Phase-shifting human circadian rhythms with exercise during the night shift. Physiol. Behav. 1995, 58:1287-1291.
    • (1995) Physiol. Behav. , vol.58 , pp. 1287-1291
    • Eastman, C.I.1
  • 18
    • 0026048367 scopus 로고
    • Regularly scheduled voluntary exercise synchronizes the mouse circadian clock
    • Edgar D.M., Dement W.C. Regularly scheduled voluntary exercise synchronizes the mouse circadian clock. Am. J. Physiol. 1991, 261:R928-R933.
    • (1991) Am. J. Physiol. , vol.261
    • Edgar, D.M.1    Dement, W.C.2
  • 19
    • 84879926757 scopus 로고    scopus 로고
    • Longitudinal analysis of the electroencephalogram and sleep phenotype in the R6/2 mouse model of Huntington's disease
    • Fisher S.P., et al. Longitudinal analysis of the electroencephalogram and sleep phenotype in the R6/2 mouse model of Huntington's disease. Brain 2013, 136:2159-2172.
    • (2013) Brain , vol.136 , pp. 2159-2172
    • Fisher, S.P.1
  • 20
    • 84882792190 scopus 로고    scopus 로고
    • Exercise attenuates neuropathology and has greater benefit on cognitive than motor deficits in the R6/1 Huntington's disease mouse model
    • Harrison D.J., et al. Exercise attenuates neuropathology and has greater benefit on cognitive than motor deficits in the R6/1 Huntington's disease mouse model. Exp. Neurol. 2013, 248:457-469.
    • (2013) Exp. Neurol. , vol.248 , pp. 457-469
    • Harrison, D.J.1
  • 21
    • 0036152343 scopus 로고    scopus 로고
    • Environmental enrichment slows disease progression in R6/2 Huntington's disease mice
    • Hockly E., et al. Environmental enrichment slows disease progression in R6/2 Huntington's disease mice. Ann. Neurol. 2002, 51:235-242.
    • (2002) Ann. Neurol. , vol.51 , pp. 235-242
    • Hockly, E.1
  • 22
    • 0032844030 scopus 로고    scopus 로고
    • Activity of serotonergic neurons in behaving animals
    • Jacobs B.L., Fornal C.A. Activity of serotonergic neurons in behaving animals. Neuropsychopharmacology 1999, 21:9S-15S.
    • (1999) Neuropsychopharmacology , vol.21
    • Jacobs, B.L.1    Fornal, C.A.2
  • 23
    • 75149133374 scopus 로고    scopus 로고
    • Conceptual evolution in Alzheimer's disease: implications for understanding the clinical phenotype of progressive neurodegenerative disease
    • Jicha G.A., Carr S.A. Conceptual evolution in Alzheimer's disease: implications for understanding the clinical phenotype of progressive neurodegenerative disease. J. Alzheimers Dis. 2010, 19:253-272.
    • (2010) J. Alzheimers Dis. , vol.19 , pp. 253-272
    • Jicha, G.A.1    Carr, S.A.2
  • 24
    • 84879928399 scopus 로고    scopus 로고
    • Progressive sleep and electroencephalogram changes in mice carrying the Huntington's disease mutation
    • Kantor S., et al. Progressive sleep and electroencephalogram changes in mice carrying the Huntington's disease mutation. Brain 2013, 136:2147-2158.
    • (2013) Brain , vol.136 , pp. 2147-2158
    • Kantor, S.1
  • 25
    • 0002918666 scopus 로고
    • The resynchronization of human circadian rhythms after transmeridian flights as a result of flight direction and mode of activity
    • Igaku Shoin LTD, Tokyo, L.E. Scheving (Ed.)
    • Klein K.E., Wegmann H.M. The resynchronization of human circadian rhythms after transmeridian flights as a result of flight direction and mode of activity. Chronobiology 1974, 564-570. Igaku Shoin LTD, Tokyo. L.E. Scheving (Ed.).
    • (1974) Chronobiology , pp. 564-570
    • Klein, K.E.1    Wegmann, H.M.2
  • 27
    • 79851513583 scopus 로고    scopus 로고
    • Dysfunctions in circadian behavior and physiology in mouse models of Huntington's disease
    • Kudo T., et al. Dysfunctions in circadian behavior and physiology in mouse models of Huntington's disease. Exp. Neurol. 2011, 228:80-90.
    • (2011) Exp. Neurol. , vol.228 , pp. 80-90
    • Kudo, T.1
  • 28
    • 77953189335 scopus 로고    scopus 로고
    • Circadian rhythms and clock genes in psychotic disorders
    • Lamont E.W., et al. Circadian rhythms and clock genes in psychotic disorders. Isr. J. Psychiatry Relat. Sci. 2010, 47:27-35.
    • (2010) Isr. J. Psychiatry Relat. Sci. , vol.47 , pp. 27-35
    • Lamont, E.W.1
  • 29
    • 0033500593 scopus 로고    scopus 로고
    • Selective discrimination learning impairments in mice expressing the human Huntington's disease mutation
    • Lione L.A., et al. Selective discrimination learning impairments in mice expressing the human Huntington's disease mutation. J. Neurosci. 1999, 19:10428-10437.
    • (1999) J. Neurosci. , vol.19 , pp. 10428-10437
    • Lione, L.A.1
  • 30
    • 0030220077 scopus 로고    scopus 로고
    • Entrainment and phase shifting of circadian rhythms in mice by forced treadmill running
    • Marchant E.G., Mistlberger R.E. Entrainment and phase shifting of circadian rhythms in mice by forced treadmill running. Physiol. Behav. 1996, 60:657-663.
    • (1996) Physiol. Behav. , vol.60 , pp. 657-663
    • Marchant, E.G.1    Mistlberger, R.E.2
  • 31
    • 77955407582 scopus 로고    scopus 로고
    • Disruption of peripheral circadian timekeeping in a mouse model of Huntington's disease and its restoration by temporally scheduled feeding
    • Maywood E.S., et al. Disruption of peripheral circadian timekeeping in a mouse model of Huntington's disease and its restoration by temporally scheduled feeding. J. Neurosci. 2010, 30:10199-10204.
    • (2010) J. Neurosci. , vol.30 , pp. 10199-10204
    • Maywood, E.S.1
  • 32
    • 0029880413 scopus 로고    scopus 로고
    • Differential serotonergic innervation of the suprachiasmatic nucleus and the intergeniculate leaflet and its role in circadian rhythm modulation
    • Meyer-Bernstein E.L., Morin L.P. Differential serotonergic innervation of the suprachiasmatic nucleus and the intergeniculate leaflet and its role in circadian rhythm modulation. J. Neurosci. 1996, 16:2097-2111.
    • (1996) J. Neurosci. , vol.16 , pp. 2097-2111
    • Meyer-Bernstein, E.L.1    Morin, L.P.2
  • 33
    • 69849094896 scopus 로고    scopus 로고
    • Food-anticipatory circadian rhythms: concepts and methods
    • Mistlberger R.E. Food-anticipatory circadian rhythms: concepts and methods. Eur. J. Neurosci. 2009, 30:1718-1729.
    • (2009) Eur. J. Neurosci. , vol.30 , pp. 1718-1729
    • Mistlberger, R.E.1
  • 35
    • 0031709183 scopus 로고    scopus 로고
    • Suprachiasmatic nucleus organization
    • Moore R.Y., Silver R. Suprachiasmatic nucleus organization. Chronobiol. Int. 1998, 15:475-487.
    • (1998) Chronobiol. Int. , vol.15 , pp. 475-487
    • Moore, R.Y.1    Silver, R.2
  • 36
    • 33746900451 scopus 로고    scopus 로고
    • The circadian visual system, 2005
    • Morin L.P., Allen C.N. The circadian visual system, 2005. Brain Res. Rev. 2006, 51:1-60.
    • (2006) Brain Res. Rev. , vol.51 , pp. 1-60
    • Morin, L.P.1    Allen, C.N.2
  • 37
    • 84875381701 scopus 로고    scopus 로고
    • Circadian and sleep disorder in Huntington's disease
    • Morton A.J. Circadian and sleep disorder in Huntington's disease. Exp. Neurol. 2013, 243:34-44.
    • (2013) Exp. Neurol. , vol.243 , pp. 34-44
    • Morton, A.J.1
  • 38
    • 12144273983 scopus 로고    scopus 로고
    • Disintegration of the sleep-wake cycle and circadian timing in Huntington's disease
    • Morton A.J., et al. Disintegration of the sleep-wake cycle and circadian timing in Huntington's disease. J. Neurosci. 2005, 25:157-163.
    • (2005) J. Neurosci. , vol.25 , pp. 157-163
    • Morton, A.J.1
  • 39
    • 84857692121 scopus 로고    scopus 로고
    • Circadian abnormalities in motor activity in a BAC transgenic mouse model of Huntington's disease
    • RRN1225
    • Oakeshott S., et al. Circadian abnormalities in motor activity in a BAC transgenic mouse model of Huntington's disease. PLoS Curr. 2011, 3:RRN1225.
    • (2011) PLoS Curr. , vol.3
    • Oakeshott, S.1
  • 40
    • 80051740344 scopus 로고    scopus 로고
    • Exercise and the treatment of diabetes and obesity
    • O'Gorman D.J., Krook A. Exercise and the treatment of diabetes and obesity. Med. Clin. North Am. 2011, 95:953-969.
    • (2011) Med. Clin. North Am. , vol.95 , pp. 953-969
    • O'Gorman, D.J.1    Krook, A.2
  • 41
    • 79961130958 scopus 로고    scopus 로고
    • Bright-light therapy in the treatment of mood disorders
    • Pail G., et al. Bright-light therapy in the treatment of mood disorders. Neuropsychobiology 2011, 64:152-162.
    • (2011) Neuropsychobiology , vol.64 , pp. 152-162
    • Pail, G.1
  • 42
    • 34447637430 scopus 로고    scopus 로고
    • Pharmacological imposition of sleep slows cognitive decline and reverses dysregulation of circadian gene expression in a transgenic mouse model of Huntington's disease
    • Pallier P.N., et al. Pharmacological imposition of sleep slows cognitive decline and reverses dysregulation of circadian gene expression in a transgenic mouse model of Huntington's disease. J. Neurosci. 2007, 27:7869-7878.
    • (2007) J. Neurosci. , vol.27 , pp. 7869-7878
    • Pallier, P.N.1
  • 43
    • 33745979171 scopus 로고    scopus 로고
    • Differential effects of voluntary exercise on behavioral and brain-derived neurotrophic factor expression deficits in Huntington's disease transgenic mice
    • Pang T.Y.C., et al. Differential effects of voluntary exercise on behavioral and brain-derived neurotrophic factor expression deficits in Huntington's disease transgenic mice. Neuroscience 2006, 141:569-584.
    • (2006) Neuroscience , vol.141 , pp. 569-584
    • Pang, T.Y.C.1
  • 44
    • 34548026072 scopus 로고    scopus 로고
    • Bright light therapy in Parkinson's disease: a pilot study
    • Paus S., et al. Bright light therapy in Parkinson's disease: a pilot study. Mov. Disord. 2007, 22:1495-1498.
    • (2007) Mov. Disord. , vol.22 , pp. 1495-1498
    • Paus, S.1
  • 45
    • 33747602312 scopus 로고    scopus 로고
    • Hypothalamic-endocrine aspects in Huntington's disease
    • Petersen A., Bjorkqvist M. Hypothalamic-endocrine aspects in Huntington's disease. Eur. J. Neurosci. 2006, 24:961-967.
    • (2006) Eur. J. Neurosci. , vol.24 , pp. 961-967
    • Petersen, A.1    Bjorkqvist, M.2
  • 46
    • 84873428789 scopus 로고    scopus 로고
    • Exercise is not beneficial and may accelerate symptom onset in a mouse model of Huntington's disease
    • RRN1201
    • Potter M.C., et al. Exercise is not beneficial and may accelerate symptom onset in a mouse model of Huntington's disease. PLoS Curr. 2010, 2:RRN1201.
    • (2010) PLoS Curr. , vol.2
    • Potter, M.C.1
  • 47
    • 84857066193 scopus 로고    scopus 로고
    • Treatment of depressive-like behaviour in Huntington's disease mice by chronic sertraline and exercise
    • Renoir T., et al. Treatment of depressive-like behaviour in Huntington's disease mice by chronic sertraline and exercise. Br. J. Pharmacol. 2012, 165:1375-1389.
    • (2012) Br. J. Pharmacol. , vol.165 , pp. 1375-1389
    • Renoir, T.1
  • 48
    • 78650031174 scopus 로고    scopus 로고
    • Huntington's disease: from molecular pathogenesis to clinical treatment
    • Ross C.A., Tabrizi S.J. Huntington's disease: from molecular pathogenesis to clinical treatment. Lancet Neurol. 2011, 10:83-98.
    • (2011) Lancet Neurol. , vol.10 , pp. 83-98
    • Ross, C.A.1    Tabrizi, S.J.2
  • 49
    • 79957606041 scopus 로고    scopus 로고
    • Etiology and pathogenesis of Parkinson's disease
    • Schapira A.H., Jenner P. Etiology and pathogenesis of Parkinson's disease. Mov. Disord. 2011, 26:1049-1055.
    • (2011) Mov. Disord. , vol.26 , pp. 1049-1055
    • Schapira, A.H.1    Jenner, P.2
  • 50
    • 0030454875 scopus 로고    scopus 로고
    • Using outdoor exercise to decrease jet lag in airline crewmembers
    • Shiota M., et al. Using outdoor exercise to decrease jet lag in airline crewmembers. Aviat. Space Environ. Med. 1996, 67:1155-1160.
    • (1996) Aviat. Space Environ. Med. , vol.67 , pp. 1155-1160
    • Shiota, M.1
  • 51
    • 79952276435 scopus 로고    scopus 로고
    • Regular physical exercise: way to healthy life
    • Siddiqui N.I., et al. Regular physical exercise: way to healthy life. Mymensingh Med. J. 2010, 19:154-158.
    • (2010) Mymensingh Med. J. , vol.19 , pp. 154-158
    • Siddiqui, N.I.1
  • 52
    • 0034643362 scopus 로고    scopus 로고
    • Delaying the onset of Huntington's in mice
    • van Dellen A., et al. Delaying the onset of Huntington's in mice. Nature 2000, 404:721-722.
    • (2000) Nature , vol.404 , pp. 721-722
    • van Dellen, A.1
  • 53
    • 42549092746 scopus 로고    scopus 로고
    • Wheel running from a juvenile age delays onset of specific motor deficits but does not alter protein aggregate density in a mouse model of Huntington's disease
    • van Dellen A., et al. Wheel running from a juvenile age delays onset of specific motor deficits but does not alter protein aggregate density in a mouse model of Huntington's disease. BMC Neurosci. 2008, 1:9-34.
    • (2008) BMC Neurosci. , vol.1 , pp. 9-34
    • van Dellen, A.1
  • 54
    • 70350746364 scopus 로고    scopus 로고
    • Food-entrainable circadian oscillators in the brain
    • Verwey M., Amir S. Food-entrainable circadian oscillators in the brain. Eur. J. Neurosci. 2009, 30:1650-1657.
    • (2009) Eur. J. Neurosci. , vol.30 , pp. 1650-1657
    • Verwey, M.1    Amir, S.2
  • 55
    • 77249131189 scopus 로고    scopus 로고
    • Circadian clock resetting by behavioral arousal: neural correlates in the midbrain raphe nuclei and locus coeruleus
    • Webb I.C., et al. Circadian clock resetting by behavioral arousal: neural correlates in the midbrain raphe nuclei and locus coeruleus. Neuroscience 2010, 166:739-751.
    • (2010) Neuroscience , vol.166 , pp. 739-751
    • Webb, I.C.1
  • 56
    • 77954344517 scopus 로고    scopus 로고
    • The effects of acute and chronic exercise on the vasculature
    • Whyte J.J., Laughlin M.H. The effects of acute and chronic exercise on the vasculature. Acta Physiol. (Oxf.) 2010, 199:441-450.
    • (2010) Acta Physiol. (Oxf.) , vol.199 , pp. 441-450
    • Whyte, J.J.1    Laughlin, M.H.2
  • 57
    • 34347385604 scopus 로고    scopus 로고
    • Primary and secondary features of Parkinson's disease improve with strategic exposure to bright light: a case series study
    • Willis G.L., Turner E.J. Primary and secondary features of Parkinson's disease improve with strategic exposure to bright light: a case series study. Chronobiol. Int. 2007, 24:521-537.
    • (2007) Chronobiol. Int. , vol.24 , pp. 521-537
    • Willis, G.L.1    Turner, E.J.2
  • 58
    • 79954628590 scopus 로고    scopus 로고
    • "Brain training" improves cognitive performance and survival in transgenic mouse model of Huntington's disease
    • Wood N.I., et al. "Brain training" improves cognitive performance and survival in transgenic mouse model of Huntington's disease. Neurobiol. Dis. 2011, 42:427-437.
    • (2011) Neurobiol. Dis. , vol.42 , pp. 427-437
    • Wood, N.I.1
  • 59
    • 84873511756 scopus 로고    scopus 로고
    • Adaptation to experimental jet-lag in R6/2 mice despite circadian dysrhythmia
    • Wood N.I., et al. Adaptation to experimental jet-lag in R6/2 mice despite circadian dysrhythmia. PLoS One 2013, 8:e55036.
    • (2013) PLoS One , vol.8
    • Wood, N.I.1


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