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Volumn 63, Issue , 2014, Pages 92-106

Developmental molecular and functional cerebellar alterations induced by PCP4/PEP19 overexpression: Implications for Down syndrome

Author keywords

Cerebellum; Down syndrome; Learning; Pcp4; Transgenic mouse

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE IIALPHA; PURKINJE CELL PROTEIN 4; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

EID: 84890824287     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2013.11.016     Document Type: Article
Times cited : (19)

References (104)
  • 1
    • 84856688136 scopus 로고    scopus 로고
    • Loss of correlations among proteins in brains of the Ts65Dn mouse model of down syndrome
    • Ahmed M.M., Sturgeon X., Ellison M., Davisson M.T., Gardiner K.J. Loss of correlations among proteins in brains of the Ts65Dn mouse model of down syndrome. J. Proteome Res. 2012, 11(2):1251-1263.
    • (2012) J. Proteome Res. , vol.11 , Issue.2 , pp. 1251-1263
    • Ahmed, M.M.1    Sturgeon, X.2    Ellison, M.3    Davisson, M.T.4    Gardiner, K.J.5
  • 4
    • 3242794941 scopus 로고    scopus 로고
    • Dosage-dependent over-expression of genes in the trisomic region of Ts1Cje mouse model for Down syndrome
    • Amano K., Sago H., Uchikawa C., Suzuki T., Kotliarova S.E., Nukina N., et al. Dosage-dependent over-expression of genes in the trisomic region of Ts1Cje mouse model for Down syndrome. Hum. Mol. Genet. 2004, 13:1333-1340.
    • (2004) Hum. Mol. Genet. , vol.13 , pp. 1333-1340
    • Amano, K.1    Sago, H.2    Uchikawa, C.3    Suzuki, T.4    Kotliarova, S.E.5    Nukina, N.6
  • 5
    • 12344252023 scopus 로고    scopus 로고
    • Neuronal subtype-specific genes that control corticospinal motor neuron development in vivo
    • Arlotta P., Molyneaux B.J., Chen J., Inoue J., Kominami R., Macklis J.D. Neuronal subtype-specific genes that control corticospinal motor neuron development in vivo. Neuron 2005, 45(2):207-221.
    • (2005) Neuron , vol.45 , Issue.2 , pp. 207-221
    • Arlotta, P.1    Molyneaux, B.J.2    Chen, J.3    Inoue, J.4    Kominami, R.5    Macklis, J.D.6
  • 6
    • 49749143326 scopus 로고    scopus 로고
    • Impaired spatial learning strategies and novel object recognition in mice haploinsufficient for the dual specificity tyrosine-regulated kinase-1A (Dyrk1A)
    • Arqué G., Fotaki V., Fernández D., Martínez de Lagrán M., Arbonés M.L., Dierssen M. Impaired spatial learning strategies and novel object recognition in mice haploinsufficient for the dual specificity tyrosine-regulated kinase-1A (Dyrk1A). PLoS One 2008, 3(7):e2575.
    • (2008) PLoS One , vol.3 , Issue.7
    • Arqué, G.1    Fotaki, V.2    Fernández, D.3    Martínez de Lagrán, M.4    Arbonés, M.L.5    Dierssen, M.6
  • 8
    • 1442349271 scopus 로고    scopus 로고
    • Distribution of calcium-binding proteins in the cerebellum
    • (Review)
    • Bastianelli E. Distribution of calcium-binding proteins in the cerebellum. Cerebellum 2003, 2:242-262. (Review).
    • (2003) Cerebellum , vol.2 , pp. 242-262
    • Bastianelli, E.1
  • 9
    • 65949098892 scopus 로고    scopus 로고
    • The "Down syndrome critical region" is sufficient in the mouse model to confer behavioral, neurophysiological, and synaptic phenotypes characteristic of Down syndrome
    • Belichenko N.P., Belichenko P.V., Kleschevnikov A.M., Salehi A., Reeves R.H., Mobley W.C. The "Down syndrome critical region" is sufficient in the mouse model to confer behavioral, neurophysiological, and synaptic phenotypes characteristic of Down syndrome. J. Neurosci. 2009, 29(18):5938-5948.
    • (2009) J. Neurosci. , vol.29 , Issue.18 , pp. 5938-5948
    • Belichenko, N.P.1    Belichenko, P.V.2    Kleschevnikov, A.M.3    Salehi, A.4    Reeves, R.H.5    Mobley, W.C.6
  • 10
    • 33644846044 scopus 로고    scopus 로고
    • 140 mouse brain proteins identified by Ca2+-calmodulin affinity chromatography and tandem mass spectrometry
    • Berggård T., Arrigoni G., Olsson O., Fex M., Linse S., James P. 140 mouse brain proteins identified by Ca2+-calmodulin affinity chromatography and tandem mass spectrometry. J. Proteome Res. 2006, 5(3):669-687.
    • (2006) J. Proteome Res. , vol.5 , Issue.3 , pp. 669-687
    • Berggård, T.1    Arrigoni, G.2    Olsson, O.3    Fex, M.4    Linse, S.5    James, P.6
  • 12
    • 79960404131 scopus 로고    scopus 로고
    • βCaMKII plays a nonenzymatic role in hippocampal synaptic plasticity and learning by targeting αCaMKII to synapses
    • Borgesius N.Z., van Woerden G.M., Buitendijk G.H., Keijzer N., Jaarsma D., Hoogenraad C.C., Elgersma Y. βCaMKII plays a nonenzymatic role in hippocampal synaptic plasticity and learning by targeting αCaMKII to synapses. J. Neurosci. 2011, 31(28):10141-10148.
    • (2011) J. Neurosci. , vol.31 , Issue.28 , pp. 10141-10148
    • Borgesius, N.Z.1    van Woerden, G.M.2    Buitendijk, G.H.3    Keijzer, N.4    Jaarsma, D.5    Hoogenraad, C.C.6    Elgersma, Y.7
  • 13
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • (7 May)
    • Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976, 72:248-254. (7 May).
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 14
    • 34648840173 scopus 로고    scopus 로고
    • Dendritic mRNA: transport, translation and function
    • (Review)
    • Bramham C.R., Wells D.G. Dendritic mRNA: transport, translation and function. Nat. Rev. Neurosci. 2007, 8(10):776-789. (Review).
    • (2007) Nat. Rev. Neurosci. , vol.8 , Issue.10 , pp. 776-789
    • Bramham, C.R.1    Wells, D.G.2
  • 15
    • 1642330422 scopus 로고    scopus 로고
    • Pcp4l1, a novel gene encoding a Pcp4-like polypeptide, is expressed in specific domains of the developing brain
    • Bulfone A., Caccioppoli C., Pardini C., Faedo A., Martinez S., Banfi S. Pcp4l1, a novel gene encoding a Pcp4-like polypeptide, is expressed in specific domains of the developing brain. Gene Expr. Patterns 2004, 4(3):297-301.
    • (2004) Gene Expr. Patterns , vol.4 , Issue.3 , pp. 297-301
    • Bulfone, A.1    Caccioppoli, C.2    Pardini, C.3    Faedo, A.4    Martinez, S.5    Banfi, S.6
  • 16
    • 0025442474 scopus 로고
    • In situ hybridization histochemistry of Ca2+/calmodulin-dependent protein kinase in developing rat brain
    • Burgin K.E., Waxham M.N., Rickling S., Westgate S.A., Mobley W.C., Kelly P.T. In situ hybridization histochemistry of Ca2+/calmodulin-dependent protein kinase in developing rat brain. J. Neurosci. 1990, 10(6):1788-1798.
    • (1990) J. Neurosci. , vol.10 , Issue.6 , pp. 1788-1798
    • Burgin, K.E.1    Waxham, M.N.2    Rickling, S.3    Westgate, S.A.4    Mobley, W.C.5    Kelly, P.T.6
  • 18
    • 4744367472 scopus 로고    scopus 로고
    • Accelerated maturation in brains of patients with Down syndrome
    • Buxhoeveden D., Casanova M.F. Accelerated maturation in brains of patients with Down syndrome. J. Intellect. Disabil. Res. 2003, 48:705-706.
    • (2003) J. Intellect. Disabil. Res. , vol.48 , pp. 705-706
    • Buxhoeveden, D.1    Casanova, M.F.2
  • 19
    • 0029985173 scopus 로고    scopus 로고
    • Molecular genetic characterization and comparative mapping of the human PCP4 gene
    • Cabin D.E., Gardiner K., Reeves R.H. Molecular genetic characterization and comparative mapping of the human PCP4 gene. Somat. Cell Mol. Genet. 1996, 22(3):167-175.
    • (1996) Somat. Cell Mol. Genet. , vol.22 , Issue.3 , pp. 167-175
    • Cabin, D.E.1    Gardiner, K.2    Reeves, R.H.3
  • 20
    • 37749024923 scopus 로고    scopus 로고
    • Neurogenesis in the cerebellum
    • (Feb., Review)
    • Carletti B., Rossi F. Neurogenesis in the cerebellum. Neuroscientist 2008, 14(1):91-100. (Feb., Review).
    • (2008) Neuroscientist , vol.14 , Issue.1 , pp. 91-100
    • Carletti, B.1    Rossi, F.2
  • 21
    • 0034633668 scopus 로고    scopus 로고
    • Presynaptic N-methyl-d-aspartate receptors at the parallel fiber-Purkinje cell synapse
    • Casado M., Dieudonné S., Ascher P. Presynaptic N-methyl-d-aspartate receptors at the parallel fiber-Purkinje cell synapse. Proc. Natl. Acad. Sci. U. S. A. 2000, 97(21):11593-11597.
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , Issue.21 , pp. 11593-11597
    • Casado, M.1    Dieudonné, S.2    Ascher, P.3
  • 22
    • 0037012097 scopus 로고    scopus 로고
    • Involvement of presynaptic N-methyl-d-aspartate receptors in cerebellar long-term depression
    • Casado M., Isope P., Ascher P. Involvement of presynaptic N-methyl-d-aspartate receptors in cerebellar long-term depression. Neuron 2002, 33(1):123-130.
    • (2002) Neuron , vol.33 , Issue.1 , pp. 123-130
    • Casado, M.1    Isope, P.2    Ascher, P.3
  • 23
    • 0034256090 scopus 로고    scopus 로고
    • Calmodulin: a prototypical calcium sensor
    • (Review. Erratum in: Trends Cell Biol 2000;10(10):428)
    • Chin D., Means A.R. Calmodulin: a prototypical calcium sensor. Trends Cell Biol. 2000, 10(8):322-328. (Review. Erratum in: Trends Cell Biol 2000;10(10):428).
    • (2000) Trends Cell Biol. , vol.10 , Issue.8 , pp. 322-328
    • Chin, D.1    Means, A.R.2
  • 24
    • 0033407499 scopus 로고    scopus 로고
    • Motor dysfunction in a mouse model for Down syndrome
    • Costa A.C., Walsh K., Davisson M.T. Motor dysfunction in a mouse model for Down syndrome. Physiol. Behav. 1999, 68(1-2):211-220.
    • (1999) Physiol. Behav. , vol.68 , Issue.1-2 , pp. 211-220
    • Costa, A.C.1    Walsh, K.2    Davisson, M.T.3
  • 25
    • 84864914128 scopus 로고    scopus 로고
    • Molecular and cellular alterations in Down syndrome: toward the identification of targets for therapeutics
    • (Review)
    • Créau N. Molecular and cellular alterations in Down syndrome: toward the identification of targets for therapeutics. Neural Plast. 2012, 2012:171639. (Review).
    • (2012) Neural Plast. , vol.2012 , pp. 171639
    • Créau, N.1
  • 26
    • 68149168768 scopus 로고    scopus 로고
    • Role of presynaptic kainate receptors at parallel fiber-Purkinje cell synapses in induction of cerebellar LTD: interplay with climbing fiber input
    • Crépel F. Role of presynaptic kainate receptors at parallel fiber-Purkinje cell synapses in induction of cerebellar LTD: interplay with climbing fiber input. J. Neurophysiol. 2009, 10(2):965-973.
    • (2009) J. Neurophysiol. , vol.10 , Issue.2 , pp. 965-973
    • Crépel, F.1
  • 28
    • 0036139184 scopus 로고    scopus 로고
    • Short-term retrograde inhibition of GABAergic synaptic currents in rat Purkinje cells is mediated by endogenous cannabinoids
    • Diana M.A., Levenes C., Mackie K., Marty A. Short-term retrograde inhibition of GABAergic synaptic currents in rat Purkinje cells is mediated by endogenous cannabinoids. J. Neurosci. 2002, 22(1):200-208.
    • (2002) J. Neurosci. , vol.22 , Issue.1 , pp. 200-208
    • Diana, M.A.1    Levenes, C.2    Mackie, K.3    Marty, A.4
  • 30
    • 67651036860 scopus 로고    scopus 로고
    • Aneuploidy: from a physiological mechanism of variance to Down syndrome
    • (Review)
    • Dierssen M., Herault Y., Estivill X. Aneuploidy: from a physiological mechanism of variance to Down syndrome. Physiol. Rev. 2009, 89(3):887-920. (Review).
    • (2009) Physiol. Rev. , vol.89 , Issue.3 , pp. 887-920
    • Dierssen, M.1    Herault, Y.2    Estivill, X.3
  • 31
    • 0028326424 scopus 로고
    • Endothelial nitric oxide synthase localized to hippocampal pyramidal cells: implications for synaptic plasticity
    • Dinerman J.L., Dawson T.M., Schell M.J., Snowman A., Snyder S.H. Endothelial nitric oxide synthase localized to hippocampal pyramidal cells: implications for synaptic plasticity. Proc. Natl. Acad. Sci. U. S. A. 1994, 91(10):4214-4218.
    • (1994) Proc. Natl. Acad. Sci. U. S. A. , vol.91 , Issue.10 , pp. 4214-4218
    • Dinerman, J.L.1    Dawson, T.M.2    Schell, M.J.3    Snowman, A.4    Snyder, S.H.5
  • 33
    • 34250178749 scopus 로고    scopus 로고
    • Object recognition memory is conserved in Ts1Cje, a mouse model of Down syndrome
    • (Jun. 27)
    • Fernandez F., Garner C.C. Object recognition memory is conserved in Ts1Cje, a mouse model of Down syndrome. Neurosci. Lett. 2007, 421(2):137-141. (Jun. 27).
    • (2007) Neurosci. Lett. , vol.421 , Issue.2 , pp. 137-141
    • Fernandez, F.1    Garner, C.C.2
  • 34
    • 0029958287 scopus 로고    scopus 로고
    • High endogenous calcium buffering in Purkinje cells from rat cerebellar slices
    • Fierro L., Llano I. High endogenous calcium buffering in Purkinje cells from rat cerebellar slices. J. Physiol. 1996, 496(Pt 3):617-625.
    • (1996) J. Physiol. , vol.496 , Issue.PART 3 , pp. 617-625
    • Fierro, L.1    Llano, I.2
  • 35
    • 33644998123 scopus 로고    scopus 로고
    • Development of the deep cerebellar nuclei: transcription factors and cell migration from the rhombic lip
    • Fink A.J., Englund C., Daza R.A., Pham D., Lau C., Nivison M., et al. Development of the deep cerebellar nuclei: transcription factors and cell migration from the rhombic lip. J. Neurosci. 2006, 26:3066-3076.
    • (2006) J. Neurosci. , vol.26 , pp. 3066-3076
    • Fink, A.J.1    Englund, C.2    Daza, R.A.3    Pham, D.4    Lau, C.5    Nivison, M.6
  • 36
    • 2842552968 scopus 로고
    • Reflex-ontogeny and behavioural development of the mouse
    • Fox W.M. Reflex-ontogeny and behavioural development of the mouse. Anim. Behav. 1965, 13(2):234-241.
    • (1965) Anim. Behav. , vol.13 , Issue.2 , pp. 234-241
    • Fox, W.M.1
  • 37
    • 0347362910 scopus 로고    scopus 로고
    • RORalpha coordinates reciprocal signaling in cerebellar development through sonic hedgehog and calcium-dependent pathways
    • Gold D.A., Baek S.H., Schork N.J., Rose D.W., Larsen D.D., Sachs B.D., Rosenfeld M.G., Hamilton B.A. RORalpha coordinates reciprocal signaling in cerebellar development through sonic hedgehog and calcium-dependent pathways. Neuron 2003, 40(6):1119-1131.
    • (2003) Neuron , vol.40 , Issue.6 , pp. 1119-1131
    • Gold, D.A.1    Baek, S.H.2    Schork, N.J.3    Rose, D.W.4    Larsen, D.D.5    Sachs, B.D.6    Rosenfeld, M.G.7    Hamilton, B.A.8
  • 38
    • 3242727011 scopus 로고    scopus 로고
    • Alteration of NO-producing system in the basal forebrain and hypothalamus of Ts65Dn mice: an immunohistochemical and histochemical study of a murine model for Down syndrome
    • Gotti S., Chiavegatto S., Sica M., Viglietti-Panzica C., Nelson R.J., Panzica G. Alteration of NO-producing system in the basal forebrain and hypothalamus of Ts65Dn mice: an immunohistochemical and histochemical study of a murine model for Down syndrome. Neurobiol. Dis. 2004, 16(3):563-571.
    • (2004) Neurobiol. Dis. , vol.16 , Issue.3 , pp. 563-571
    • Gotti, S.1    Chiavegatto, S.2    Sica, M.3    Viglietti-Panzica, C.4    Nelson, R.J.5    Panzica, G.6
  • 39
    • 0025770112 scopus 로고
    • Postnatal expression of glutamate decarboxylases in developing rat cerebellum
    • Greif K.F., Erlander M.G., Tillakaratne N.J., Tobin A.J. Postnatal expression of glutamate decarboxylases in developing rat cerebellum. Neurochem. Res. 1991, 16(3):235-242.
    • (1991) Neurochem. Res. , vol.16 , Issue.3 , pp. 235-242
    • Greif, K.F.1    Erlander, M.G.2    Tillakaratne, N.J.3    Tobin, A.J.4
  • 40
    • 84858156775 scopus 로고    scopus 로고
    • DYRK1A: a master regulatory protein controlling brain growth
    • (Erratum in: Neurobiol Dis 2012;47(2):294)
    • Guedj F., Pereira P.L., Najas S., Barallobre M.J., Chabert C., Souchet B., et al. DYRK1A: a master regulatory protein controlling brain growth. Neurobiol. Dis. 2012, 46(1):190-203. (Erratum in: Neurobiol Dis 2012;47(2):294).
    • (2012) Neurobiol. Dis. , vol.46 , Issue.1 , pp. 190-203
    • Guedj, F.1    Pereira, P.L.2    Najas, S.3    Barallobre, M.J.4    Chabert, C.5    Souchet, B.6
  • 41
    • 0033565768 scopus 로고    scopus 로고
    • Differential activation of adenylyl cyclases by spatial and procedural learning
    • Guillou J.L., Rose G.M., Cooper D.M. Differential activation of adenylyl cyclases by spatial and procedural learning. J. Neurosci. 1999, 19(14):6183-6190.
    • (1999) J. Neurosci. , vol.19 , Issue.14 , pp. 6183-6190
    • Guillou, J.L.1    Rose, G.M.2    Cooper, D.M.3
  • 42
    • 84884579475 scopus 로고    scopus 로고
    • Size does not always matter: Ts65Dn down syndrome mice show cerebellum-dependent motor learning deficits that cannot be rescued by postnatal sag treatment
    • Gutierrez-Castellanos N., Winkelman B.H., Tolosa-Rodriguez L., Devenney B., Reeves R.H., De Zeeuw C.I. Size does not always matter: Ts65Dn down syndrome mice show cerebellum-dependent motor learning deficits that cannot be rescued by postnatal sag treatment. J. Neurosci. 2013, 3(39):15408-15413.
    • (2013) J. Neurosci. , vol.3 , Issue.39 , pp. 15408-15413
    • Gutierrez-Castellanos, N.1    Winkelman, B.H.2    Tolosa-Rodriguez, L.3    Devenney, B.4    Reeves, R.H.5    De Zeeuw, C.I.6
  • 44
    • 36849062574 scopus 로고    scopus 로고
    • The dynamic network subserving the three phases of cognitive procedural learning
    • Hubert V., Beaunieux H., Chételat G., Platel H., Landeau B., Danion J.M., et al. The dynamic network subserving the three phases of cognitive procedural learning. Hum. Brain Mapp. 2007, 28(12):1415-1429.
    • (2007) Hum. Brain Mapp. , vol.28 , Issue.12 , pp. 1415-1429
    • Hubert, V.1    Beaunieux, H.2    Chételat, G.3    Platel, H.4    Landeau, B.5    Danion, J.M.6
  • 45
    • 0037097022 scopus 로고    scopus 로고
    • Structure-function of the multifunctional Ca2+/calmodulin-dependent protein kinase II
    • (Review)
    • Hudmon A., Schulman H. Structure-function of the multifunctional Ca2+/calmodulin-dependent protein kinase II. Biochem. J. 2002, 364(Pt 3):593-611. (Review).
    • (2002) Biochem. J. , vol.364 , Issue.PART 3 , pp. 593-611
    • Hudmon, A.1    Schulman, H.2
  • 46
    • 14844337861 scopus 로고    scopus 로고
    • Peptide 19 in the rat vagal and glossopharyngeal sensory ganglia
    • Ichikawa H., Sugimoto T. Peptide 19 in the rat vagal and glossopharyngeal sensory ganglia. Brain Res. 2005, 1038:107-112.
    • (2005) Brain Res. , vol.1038 , pp. 107-112
    • Ichikawa, H.1    Sugimoto, T.2
  • 47
    • 0033528468 scopus 로고    scopus 로고
    • Peptide 19 in the dorsal root ganglion and the mesencephalic trigeminal tract nucleus of the adult rat
    • Ichikawa H., Morgan J.I., Sugimoto T. Peptide 19 in the dorsal root ganglion and the mesencephalic trigeminal tract nucleus of the adult rat. Brain Res. 1999, 821:231-235.
    • (1999) Brain Res. , vol.821 , pp. 231-235
    • Ichikawa, H.1    Morgan, J.I.2    Sugimoto, T.3
  • 48
    • 1242296344 scopus 로고    scopus 로고
    • Immunohistochemical characterization of the orphan nuclear receptor ROR alpha in the mouse nervous system
    • (Mar.)
    • Ino H. Immunohistochemical characterization of the orphan nuclear receptor ROR alpha in the mouse nervous system. J. Histochem. Cytochem. 2004, 52(3):311-323. (Mar.).
    • (2004) J. Histochem. Cytochem. , vol.52 , Issue.3 , pp. 311-323
    • Ino, H.1
  • 49
    • 0034655394 scopus 로고    scopus 로고
    • Calmodulin-binding peptide PEP-19 modulates activation of calmodulin kinase II In situ
    • Johanson R.A., Sarau H.M., Foley J.J., Slemmon J.R. Calmodulin-binding peptide PEP-19 modulates activation of calmodulin kinase II In situ. J. Neurosci. 2000, 20:2860-2866.
    • (2000) J. Neurosci. , vol.20 , pp. 2860-2866
    • Johanson, R.A.1    Sarau, H.M.2    Foley, J.J.3    Slemmon, J.R.4
  • 50
    • 0042287970 scopus 로고    scopus 로고
    • Investigation of differentially expressed genes during the development of mouse cerebellum
    • Kagami Y., Furuichi T. Investigation of differentially expressed genes during the development of mouse cerebellum. Brain Res. Gene Expr. Patterns 2001, 1(1):39-59.
    • (2001) Brain Res. Gene Expr. Patterns , vol.1 , Issue.1 , pp. 39-59
    • Kagami, Y.1    Furuichi, T.2
  • 51
    • 3543110316 scopus 로고    scopus 로고
    • Transcript level alterations reflect gene dosage effects across multiple tissues in a mouse model of down syndrome
    • Kahlem P., Sultan M., Herwig R., Steinfath M., Balzereit D., Eppens B., et al. Transcript level alterations reflect gene dosage effects across multiple tissues in a mouse model of down syndrome. Genome Res. 2004, 14:1258-1267.
    • (2004) Genome Res. , vol.14 , pp. 1258-1267
    • Kahlem, P.1    Sultan, M.2    Herwig, R.3    Steinfath, M.4    Balzereit, D.5    Eppens, B.6
  • 52
    • 79958033258 scopus 로고    scopus 로고
    • Synaptophysin regulates the kinetics of synaptic vesicle endocytosis in central neurons
    • Kwon S.E., Chapman E.R. Synaptophysin regulates the kinetics of synaptic vesicle endocytosis in central neurons. Neuron 2011, 70(5):847-854.
    • (2011) Neuron , vol.70 , Issue.5 , pp. 847-854
    • Kwon, S.E.1    Chapman, E.R.2
  • 53
    • 65549148290 scopus 로고    scopus 로고
    • Gene expression signature of cerebellar hypoplasia in a mouse model of Down syndrome during postnatal development
    • Laffaire J., Rivals I., Dauphinot L., Pasteau F., Wehrle R., Larrat B., et al. Gene expression signature of cerebellar hypoplasia in a mouse model of Down syndrome during postnatal development. BMC Genomics 2009, 10:138.
    • (2009) BMC Genomics , vol.10 , pp. 138
    • Laffaire, J.1    Rivals, I.2    Dauphinot, L.3    Pasteau, F.4    Wehrle, R.5    Larrat, B.6
  • 54
    • 0002565635 scopus 로고    scopus 로고
    • Motor coordination in Down syndrome: the role of adaptive changes
    • Human Kinetics Inc. D.J. Weeks, R. Chua, D. Elliott (Eds.)
    • Latash M.L. Motor coordination in Down syndrome: the role of adaptive changes. Perceptual-motor Behavior in Down Syndrome 2000, 199-224. Human Kinetics Inc. D.J. Weeks, R. Chua, D. Elliott (Eds.).
    • (2000) Perceptual-motor Behavior in Down Syndrome , pp. 199-224
    • Latash, M.L.1
  • 55
    • 0033067775 scopus 로고    scopus 로고
    • Cerebellar contribution to spatial event processing: characterization of procedural learning
    • Leggio M.G., Neri P., Graziano A., Mandolesi L., Molinari M., Petrosini L. Cerebellar contribution to spatial event processing: characterization of procedural learning. Exp. Brain Res. 1999, 127(1):1-11.
    • (1999) Exp. Brain Res. , vol.127 , Issue.1 , pp. 1-11
    • Leggio, M.G.1    Neri, P.2    Graziano, A.3    Mandolesi, L.4    Molinari, M.5    Petrosini, L.6
  • 56
    • 16844366957 scopus 로고    scopus 로고
    • Redefining the boundaries of the hippocampal CA2 subfield in the mouse using gene expression and 3-dimensional reconstruction
    • Lein E.S., Callaway E.M., Albright T.D., Gage F.H. Redefining the boundaries of the hippocampal CA2 subfield in the mouse using gene expression and 3-dimensional reconstruction. J. Comp. Neurol. 2005, 485(1):1-10.
    • (2005) J. Comp. Neurol. , vol.485 , Issue.1 , pp. 1-10
    • Lein, E.S.1    Callaway, E.M.2    Albright, T.D.3    Gage, F.H.4
  • 57
    • 0025801411 scopus 로고
    • Calcium entry increases the sensitivity of cerebellar Purkinje cells to applied GABA and decreases inhibitory synaptic currents
    • Llano I., Leresche N., Marty A. Calcium entry increases the sensitivity of cerebellar Purkinje cells to applied GABA and decreases inhibitory synaptic currents. Neuron 1991, 6:565-574.
    • (1991) Neuron , vol.6 , pp. 565-574
    • Llano, I.1    Leresche, N.2    Marty, A.3
  • 58
    • 0037101835 scopus 로고    scopus 로고
    • Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain
    • Luthi-Carter R., Hanson S.A., Strand A.D., Bergstrom D.A., Chun W., Peters N.L., et al. Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain. Hum. Mol. Genet. 2002, 11(17):1911-1926.
    • (2002) Hum. Mol. Genet. , vol.11 , Issue.17 , pp. 1911-1926
    • Luthi-Carter, R.1    Hanson, S.A.2    Strand, A.D.3    Bergstrom, D.A.4    Chun, W.5    Peters, N.L.6
  • 59
    • 3543097554 scopus 로고    scopus 로고
    • Gene expression from the aneuploid chromosome in a trisomy mouse model of down syndrome
    • Lyle R., Gehrig C., Neergaard-Henrichsen C., Deutsch S., Antonarakis S.E. Gene expression from the aneuploid chromosome in a trisomy mouse model of down syndrome. Genome Res. 2004, 14:1268-1274.
    • (2004) Genome Res. , vol.14 , pp. 1268-1274
    • Lyle, R.1    Gehrig, C.2    Neergaard-Henrichsen, C.3    Deutsch, S.4    Antonarakis, S.E.5
  • 60
    • 0021894210 scopus 로고
    • Ca2+/calmodulin-dependent protein kinase II. Isozymic forms from rat forebrain and cerebellum
    • McGuinness T.L., Lai Y., Greengard P. Ca2+/calmodulin-dependent protein kinase II. Isozymic forms from rat forebrain and cerebellum. J. Biol. Chem. 1985, 260(3):1696-1704.
    • (1985) J. Biol. Chem. , vol.260 , Issue.3 , pp. 1696-1704
    • McGuinness, T.L.1    Lai, Y.2    Greengard, P.3
  • 61
    • 0022258786 scopus 로고
    • Distinct forebrain and cerebellar isozymes of type II Ca2+/calmodulin-dependent protein kinase associate differently with the postsynaptic density fraction
    • Miller S.G., Kennedy M.B. Distinct forebrain and cerebellar isozymes of type II Ca2+/calmodulin-dependent protein kinase associate differently with the postsynaptic density fraction. J. Biol. Chem. 1985, 260(15):9039-9046.
    • (1985) J. Biol. Chem. , vol.260 , Issue.15 , pp. 9039-9046
    • Miller, S.G.1    Kennedy, M.B.2
  • 62
    • 0037168109 scopus 로고    scopus 로고
    • Disruption of dendritic translation of CaMKIIalpha impairs stabilization of synaptic plasticity and memory consolidation
    • Miller S., Yasuda M., Coats J.K., Jones Y., Martone M.E., Mayford M. Disruption of dendritic translation of CaMKIIalpha impairs stabilization of synaptic plasticity and memory consolidation. Neuron 2002, 36(3):507-519.
    • (2002) Neuron , vol.36 , Issue.3 , pp. 507-519
    • Miller, S.1    Yasuda, M.2    Coats, J.K.3    Jones, Y.4    Martone, M.E.5    Mayford, M.6
  • 64
    • 47549096987 scopus 로고    scopus 로고
    • Preservation of long-term memory and synaptic plasticity despite short-term impairments in the Tc1 mouse model of Down syndrome
    • (Jul. 14)
    • Morice E., Andreae L.C., Cooke S.F., Vanes L., Fisher E.M., Tybulewicz V.L., Bliss T.V. Preservation of long-term memory and synaptic plasticity despite short-term impairments in the Tc1 mouse model of Down syndrome. Learn. Mem. 2008, 15(7):492-500. (Jul. 14).
    • (2008) Learn. Mem. , vol.15 , Issue.7 , pp. 492-500
    • Morice, E.1    Andreae, L.C.2    Cooke, S.F.3    Vanes, L.4    Fisher, E.M.5    Tybulewicz, V.L.6    Bliss, T.V.7
  • 65
    • 0033646251 scopus 로고    scopus 로고
    • Evidence for a deficit in procedural learning in children and adolescents with autism: implications for cerebellar contribution
    • Mostofsky S.H., Goldberg M.C., Landa R.J., Denckla M.B. Evidence for a deficit in procedural learning in children and adolescents with autism: implications for cerebellar contribution. J. Int. Neuropsychol. Soc. 2000, 6(7):752-759.
    • (2000) J. Int. Neuropsychol. Soc. , vol.6 , Issue.7 , pp. 752-759
    • Mostofsky, S.H.1    Goldberg, M.C.2    Landa, R.J.3    Denckla, M.B.4
  • 66
    • 80053259489 scopus 로고    scopus 로고
    • PCP4 (PEP19) overexpression induces premature neuronal differentiation associated with Ca(2+)/calmodulin-dependent kinase II-δ activation in mouse models of Down syndrome
    • (Erratum in: J Comp Neurol. 2011;519(17):3597)
    • Mouton-Liger F., Thomas S., Rattenbach R., Magnol L., Larigaldie V., Ledru A., et al. PCP4 (PEP19) overexpression induces premature neuronal differentiation associated with Ca(2+)/calmodulin-dependent kinase II-δ activation in mouse models of Down syndrome. J. Comp. Neurol. 2011, 519(14):2779-2802. (Erratum in: J Comp Neurol. 2011;519(17):3597).
    • (2011) J. Comp. Neurol. , vol.519 , Issue.14 , pp. 2779-2802
    • Mouton-Liger, F.1    Thomas, S.2    Rattenbach, R.3    Magnol, L.4    Larigaldie, V.5    Ledru, A.6
  • 67
    • 0023949656 scopus 로고
    • The polypeptide PEP-19 is a marker for Purkinje neurons in cerebellar cortex and cartwheel neurons in the dorsal cochlear nucleus
    • Mugnaini E., Berrebi A.S., Dahl A.L., Morgan J.I. The polypeptide PEP-19 is a marker for Purkinje neurons in cerebellar cortex and cartwheel neurons in the dorsal cochlear nucleus. Arch. Ital. Biol. 1987, 126:41-67.
    • (1987) Arch. Ital. Biol. , vol.126 , pp. 41-67
    • Mugnaini, E.1    Berrebi, A.S.2    Dahl, A.L.3    Morgan, J.I.4
  • 68
    • 33846916150 scopus 로고    scopus 로고
    • Nucleus- and cell-specific gene expression in monkey thalamus
    • Murray K.D., Choudary P.V., Jones E.G. Nucleus- and cell-specific gene expression in monkey thalamus. Proc. Natl. Acad. Sci. U. S. A. 2007, 104(6):1989-1994.
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , Issue.6 , pp. 1989-1994
    • Murray, K.D.1    Choudary, P.V.2    Jones, E.G.3
  • 69
    • 3042612213 scopus 로고    scopus 로고
    • Down syndrome mouse models Ts65Dn, Ts1Cje, and Ms1Cje/Ts65Dn exhibit variable severity of cerebellar phenotypes
    • Olson L.E., Roper R.J., Baxter L.L., Carlson E.J., Epstein C.J., Reeves R.H. Down syndrome mouse models Ts65Dn, Ts1Cje, and Ms1Cje/Ts65Dn exhibit variable severity of cerebellar phenotypes. Dev. Dyn. 2004, 230(3):581-589.
    • (2004) Dev. Dyn. , vol.230 , Issue.3 , pp. 581-589
    • Olson, L.E.1    Roper, R.J.2    Baxter, L.L.3    Carlson, E.J.4    Epstein, C.J.5    Reeves, R.H.6
  • 71
    • 0038687498 scopus 로고    scopus 로고
    • The neuropsychology of Down syndrome: evidence for hippocampal dysfunction
    • Pennington B.F., Moon J., Edgin J., Stedron J., Nadel L. The neuropsychology of Down syndrome: evidence for hippocampal dysfunction. Child Dev. 2003, 74(1):75-93.
    • (2003) Child Dev. , vol.74 , Issue.1 , pp. 75-93
    • Pennington, B.F.1    Moon, J.2    Edgin, J.3    Stedron, J.4    Nadel, L.5
  • 73
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl M.W. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 2001, 29:e45.
    • (2001) Nucleic Acids Res. , vol.29
    • Pfaffl, M.W.1
  • 75
    • 0038449825 scopus 로고    scopus 로고
    • Transcriptional profiling of neuronal differentiation by human embryonal carcinoma stem cells in vitro
    • Przyborski S.A., Smith S., Wood A. Transcriptional profiling of neuronal differentiation by human embryonal carcinoma stem cells in vitro. Stem Cells 2003, 21(4):459-471.
    • (2003) Stem Cells , vol.21 , Issue.4 , pp. 459-471
    • Przyborski, S.A.1    Smith, S.2    Wood, A.3
  • 76
    • 0347379936 scopus 로고    scopus 로고
    • A new role for IQ motif proteins in regulating calmodulin function
    • Putkey J.A., Kleerekoper Q., Gaertner T.R., Waxham M.N. A new role for IQ motif proteins in regulating calmodulin function. J. Biol. Chem. 2003, 278:49667-49670.
    • (2003) J. Biol. Chem. , vol.278 , pp. 49667-49670
    • Putkey, J.A.1    Kleerekoper, Q.2    Gaertner, T.R.3    Waxham, M.N.4
  • 81
    • 0032568615 scopus 로고    scopus 로고
    • Ts1Cje, a partial trisomy 16 mouse model for Down syndrome, exhibits learning and behavioral abnormalities
    • Sago H., Carlson E.J., Smith D.J., Kilbridge J., Rubin E.M., Mobley W.C., et al. Ts1Cje, a partial trisomy 16 mouse model for Down syndrome, exhibits learning and behavioral abnormalities. Proc. Natl. Acad. Sci. U. S. A. 1998, 95:6256-6261.
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 6256-6261
    • Sago, H.1    Carlson, E.J.2    Smith, D.J.3    Kilbridge, J.4    Rubin, E.M.5    Mobley, W.C.6
  • 82
    • 0033756144 scopus 로고    scopus 로고
    • Genetic dissection of region associated with behavioral abnormalities in mouse models for Down syndrome
    • (Nov.)
    • Sago H., Carlson E.J., Smith D.J., Rubin E.M., Crnic L.S., Huang T.T., Epstein C.J. Genetic dissection of region associated with behavioral abnormalities in mouse models for Down syndrome. Pediatr. Res. 2000, 48(5):606-613. (Nov.).
    • (2000) Pediatr. Res. , vol.48 , Issue.5 , pp. 606-613
    • Sago, H.1    Carlson, E.J.2    Smith, D.J.3    Rubin, E.M.4    Crnic, L.S.5    Huang, T.T.6    Epstein, C.J.7
  • 84
    • 0024312665 scopus 로고
    • Molecular cloning of a neuron-specific transcript and its regulation during normal and aberrant cerebellar development
    • Sangameswaran L., Hempstead J., Morgan J.I. Molecular cloning of a neuron-specific transcript and its regulation during normal and aberrant cerebellar development. Proc. Natl. Acad. Sci. U. S. A. 1989, 86(14):5651-5655.
    • (1989) Proc. Natl. Acad. Sci. U. S. A. , vol.86 , Issue.14 , pp. 5651-5655
    • Sangameswaran, L.1    Hempstead, J.2    Morgan, J.I.3
  • 85
    • 72949124431 scopus 로고    scopus 로고
    • The treasury of the commons: making use of public gene expression resources to better characterize the molecular diversity of inhibitory interneurons in the cerebellar cortex
    • Schilling K., Oberdick J. The treasury of the commons: making use of public gene expression resources to better characterize the molecular diversity of inhibitory interneurons in the cerebellar cortex. Cerebellum 2009, 8(4):477-489.
    • (2009) Cerebellum , vol.8 , Issue.4 , pp. 477-489
    • Schilling, K.1    Oberdick, J.2
  • 86
    • 17844410932 scopus 로고    scopus 로고
    • Scanning the human proteome for calmodulin-binding proteins
    • (Erratum in: Proc Natl Acad Sci U S A. 2005;102(27):9734. Szostak, Jack [corrected to Szostak, Jack W])
    • Shen X., Valencia C.A., Szostak J.W., Dong B., Liu R. Scanning the human proteome for calmodulin-binding proteins. Proc. Natl. Acad. Sci. U. S. A. 2005, 102(17):5969-5974. (Erratum in: Proc Natl Acad Sci U S A. 2005;102(27):9734. Szostak, Jack [corrected to Szostak, Jack W]).
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , Issue.17 , pp. 5969-5974
    • Shen, X.1    Valencia, C.A.2    Szostak, J.W.3    Dong, B.4    Liu, R.5
  • 87
    • 69549126585 scopus 로고    scopus 로고
    • Regional differences in hippocampal calcium handling provide a cellular mechanism for limiting plasticity
    • Simons S.B., Escobedo Y., Yasuda R., Dudek S.M. Regional differences in hippocampal calcium handling provide a cellular mechanism for limiting plasticity. Proc. Natl. Acad. Sci. U. S. A. 2009, 106(33):14080-14084.
    • (2009) Proc. Natl. Acad. Sci. U. S. A. , vol.106 , Issue.33 , pp. 14080-14084
    • Simons, S.B.1    Escobedo, Y.2    Yasuda, R.3    Dudek, S.M.4
  • 88
    • 0028215986 scopus 로고
    • Increased levels of hemoglobin-derived and other peptides in Alzheimer's disease cerebellum
    • Slemmon J.R., Hughes C.M., Campbell G.A., Flood D.G. Increased levels of hemoglobin-derived and other peptides in Alzheimer's disease cerebellum. J. Neurosci. 1994, 14(4):2225-2235.
    • (1994) J. Neurosci. , vol.14 , Issue.4 , pp. 2225-2235
    • Slemmon, J.R.1    Hughes, C.M.2    Campbell, G.A.3    Flood, D.G.4
  • 89
    • 0030036476 scopus 로고    scopus 로고
    • Camstatins are peptide antagonists of calmodulin based upon a conserved structural motif in PEP-19, neurogranin, and neuromodulin
    • Slemmon J.R., Morgan J.I., Fullerton S.M., Danho W., Hilbush B.S., Wengenack T.M. Camstatins are peptide antagonists of calmodulin based upon a conserved structural motif in PEP-19, neurogranin, and neuromodulin. J. Biol. Chem. 1996, 271:15911-15917.
    • (1996) J. Biol. Chem. , vol.271 , pp. 15911-15917
    • Slemmon, J.R.1    Morgan, J.I.2    Fullerton, S.M.3    Danho, W.4    Hilbush, B.S.5    Wengenack, T.M.6
  • 90
    • 0037168115 scopus 로고    scopus 로고
    • MRNA at synapses, synaptic plasticity, and memory consolidation
    • Steward O. mRNA at synapses, synaptic plasticity, and memory consolidation. Neuron 2002, 36(3):338-340.
    • (2002) Neuron , vol.36 , Issue.3 , pp. 338-340
    • Steward, O.1
  • 91
    • 0141918785 scopus 로고    scopus 로고
    • Compartmentalized synthesis and degradation of proteins in neurons
    • Steward O., Schuman E.M. Compartmentalized synthesis and degradation of proteins in neurons. Neuron 2003, 40(2):347-359.
    • (2003) Neuron , vol.40 , Issue.2 , pp. 347-359
    • Steward, O.1    Schuman, E.M.2
  • 93
    • 80051667850 scopus 로고    scopus 로고
    • Activation of a δFOSB dependent gene expression pattern in the dorsolateral prefrontal cortex of patients with major depressive disorder
    • Teyssier J.R., Ragot S., Chauvet-Gélinier J.C., Trojak B., Bonin B. Activation of a δFOSB dependent gene expression pattern in the dorsolateral prefrontal cortex of patients with major depressive disorder. J. Affect. Disord. 2011, 133(1-2):174-178.
    • (2011) J. Affect. Disord. , vol.133 , Issue.1-2 , pp. 174-178
    • Teyssier, J.R.1    Ragot, S.2    Chauvet-Gélinier, J.C.3    Trojak, B.4    Bonin, B.5
  • 96
    • 0032543782 scopus 로고    scopus 로고
    • PEP-19 immunohistochemistry defines the basal ganglia and associated structures in the adult human brain, and is dramatically reduced in Huntington's disease
    • Utal A.K., Stopka A.L., Roy M., Coleman P.D. PEP-19 immunohistochemistry defines the basal ganglia and associated structures in the adult human brain, and is dramatically reduced in Huntington's disease. Neuroscience 1998, 86:1055-1063.
    • (1998) Neuroscience , vol.86 , pp. 1055-1063
    • Utal, A.K.1    Stopka, A.L.2    Roy, M.3    Coleman, P.D.4
  • 97
    • 0034035255 scopus 로고    scopus 로고
    • Astrocytes express specific variants of CaM KII delta and gamma, but not alpha and beta, that determine their cellular localizations
    • Vallano M.L., Beaman-Hall C.M., Mathur A., Chen Q. Astrocytes express specific variants of CaM KII delta and gamma, but not alpha and beta, that determine their cellular localizations. Glia 2000, 30(2):154-164.
    • (2000) Glia , vol.30 , Issue.2 , pp. 154-164
    • Vallano, M.L.1    Beaman-Hall, C.M.2    Mathur, A.3    Chen, Q.4
  • 98
    • 79955658128 scopus 로고    scopus 로고
    • The metamorphosis of the developing cerebellar microcircuit
    • van Welie I., Smith I.T., Watt A.J. The metamorphosis of the developing cerebellar microcircuit. Curr. Opin. Neurobiol. 2011, 21(2):245-253.
    • (2011) Curr. Opin. Neurobiol. , vol.21 , Issue.2 , pp. 245-253
    • van Welie, I.1    Smith, I.T.2    Watt, A.J.3
  • 100
    • 84872732638 scopus 로고    scopus 로고
    • The calmodulin regulator protein, PEP-19, sensitizes ATP-induced Ca2+ release
    • Wang X., Xiong L.W., El Ayadi A., Boehning D., Putkey J.A. The calmodulin regulator protein, PEP-19, sensitizes ATP-induced Ca2+ release. J. Biol. Chem. 2013, 288(3):2040-2048.
    • (2013) J. Biol. Chem. , vol.288 , Issue.3 , pp. 2040-2048
    • Wang, X.1    Xiong, L.W.2    El Ayadi, A.3    Boehning, D.4    Putkey, J.A.5
  • 102
    • 79960361662 scopus 로고    scopus 로고
    • Impaired locomotor learning and altered cerebellar synaptic plasticity in pep-19/PCP4-null mice
    • Wei P., Blundon J.A., Rong Y., Zakharenko S.S., Morgan J.I. Impaired locomotor learning and altered cerebellar synaptic plasticity in pep-19/PCP4-null mice. Mol. Cell. Biol. 2011, 31(14):2838-2844.
    • (2011) Mol. Cell. Biol. , vol.31 , Issue.14 , pp. 2838-2844
    • Wei, P.1    Blundon, J.A.2    Rong, Y.3    Zakharenko, S.S.4    Morgan, J.I.5
  • 103
    • 0032215079 scopus 로고    scopus 로고
    • CPEB-mediated cytoplasmic polyadenylation and the regulation of experience-dependent translation of alpha-CaMKII mRNA at synapses
    • Wu L., Wells D., Tay J., Mendis D., Abbott M.A., Barnitt A., et al. CPEB-mediated cytoplasmic polyadenylation and the regulation of experience-dependent translation of alpha-CaMKII mRNA at synapses. Neuron 1998, 21(5):1129-1139.
    • (1998) Neuron , vol.21 , Issue.5 , pp. 1129-1139
    • Wu, L.1    Wells, D.2    Tay, J.3    Mendis, D.4    Abbott, M.A.5    Barnitt, A.6


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