Protective effect of turmeric extract on methotrexate-induced intestinal damage and oxidative stress

Chinese Journal of Natural Medicines

Volumn 11, Issue 5, 2013, Pages 477-483

  Moghadam, Adel Rezaei ^a,b   Mohajeri, Daryoush ^b   Namvaran Abbas Abad, Ali ^b   Manafi, Hamed ^b   Shahi, Delavar ^b   Mazani, Mohammad ^c  

^a ISLAMIC AZAD UNIVERSITY   (Iran)

^b ISLAMIC AZAD UNIVERSITY   (Iran)

^c ARDABIL UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Intestinal damage; Methotrexate; Oxidative stress; Turmeric

Indexed keywords

CATALASE; CURCUMA LONGA EXTRACT; MALONALDEHYDE; METHOTREXATE; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD SAMPLING; CELL DEATH; CELL INFILTRATION; CONTROLLED STUDY; EPITHELIUM CELL; GASTROINTESTINAL HEMORRHAGE; HISTOPATHOLOGY; INFLAMMATORY CELL; INTESTINE INJURY; JEJUNUM; LAMINA PROPRIA; LIPID PEROXIDATION; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; WISTAR ALBINO GLAXO RAT;

INTESTINAL DAMAGE; METHOTREXATE; OXIDATIVE STRESS; TURMERIC;

ANIMALS; CATALASE; CURCUMA; GLUTATHIONE PEROXIDASE; HUMANS; INTESTINAL DISEASES; INTESTINES; MALE; MALONDIALDEHYDE; METHOTREXATE; OXIDATIVE STRESS; PLANT EXTRACTS; RATS; RATS, WISTAR; SUPEROXIDE DISMUTASE;

EID: 84890822075     PISSN: 20956975     EISSN: 18755364     Source Type: Journal    
DOI: 10.1016/S1875-5364(13)60087-4     Document Type: Article

References (28)

1. Gulgun M, Erdem O, Oztas E, et al. Proanthocyanidin prevents methotrexate-induced intestinal damage and oxidative stress [J]. Exp Toxicol Pathol 2010, 62(2):109-115.
2. Jahovic N, Sener G, Cevik H, et al. Amelioration of methotrexate-induced enteritis by melatonin in rats [J]. Cell Biochem Funct 2004, 22(3):169-178.
3. Miyazono Y, Gao F, Horie T Oxidative stress contributes to methotrexate-induced small intestinal toxicity in rats [J]. Scand J Gastroenterol 2004, 39(11):1119-1127.
4. Yuncu M, Eralp A, Celik A Effect of aged garlic extract against methotrexate-induced damage to the small intestine in rats [J]. Phytother Res 2006, 20(6):504-510.
5. Gao F, Horie T A synthetic analog of prostaglandin E(1) prevents the production of reactive oxygen species in the intestinal mucosa of methotrexate-treated rats [J]. Life Sci 2002, 19(9):1091-1099. 71.
6. Namvaran Abbas Abad A, Kayate Nouri MH, Gharjanie A, et al. Effect of Matricaria chamomilla hydroalcoholic extract on cisplatin-induced neuropathy in mice [J]. Chin J Nat Med 2011, 9(2):126-131.
7. Namvaran Abbas Abad A, Khayate Nouri MH, Tavakkoli F Effect of Salvia officinalis hydroalcoholic extract on vincristine-induced neuropathy in mice [J]. Chin J Nat Med 2011, 9(5):354-358.
8. Namvaran-Abbas-Abad A, Tavakkoli F Antinociceptive effect of salvia extract on cisplatin-induced hyperalgesia in mice [J]. Neurophysiology 2012, 43(6):452-458.
9. Ak T, Gulcin I Antioxidant and radical scavenging properties of curcumin [J]. Chem Biol Interact 2008, 174(1):27-37.
10. Sandur SK, Ichikawa H, Pandey MK, et al. Role of pro-oxidants and antioxidants in the anti-inflammatory and apoptotic effects of curcumin (diferuloylmethane) [J]. Free Radic Biol Med 2007, 43(4):568-580.
11. Kota N, Krishna P, Polasa K Alterations in antioxidant status of rats following intake of ginger through diet [J]. Food Chem 2008, 106(3):991-996.
12. Katiyar SK, Agarwal R, Mukhtar H Inhibition of tumor promotion in SENCAR mouse skin by ethanol extract of Zingiber officinale rhizome [J]. Cancer Res 1996, 56(5):1023-1030.
13. Erel O A novel automated method to measure total antioxidant response against potent free radical reactions [J]. Clin Biochem 2004, 37(2):112-119.
14. Paoletti F, Aldinucci D, Mocali A, et al. A sensitive spectrophotometric method for the determination of superoxide dismutase activity in tissue extracts [J]. Anal Biochem 1986, 154(2):536-541.
15. Paglia DE, Valentine WN Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase [J]. J Lab Clin Med 1967, 70(1):158-169.
16. Claiborne A Handbook of Methods for Oxygen Radical Research [M] 1985, CRC Press, Florida, America.
17. Kaya H, Sezik M, Ozkaya O, et al. Lipid peroxidation at various estradiol concentrations in human circulation during ovarian stimulation with exogenous gonadotropins [J]. Horm Metab Res 2004, 36(10):693-695.
18. Kremer JM Toward a better understanding of methotrexate [J]. Arthritis Rheum 2004, 50(5):1370-1382.
19. Pinkerton CR, Milla PJ Methotrexate enterotoxicity: influence of drug dose and timing in the rat [J]. Br J Cancer 1984, 49(1):97-101.
20. Papaconstantinou HT, Xie C, Zhang W, et al. The role of caspases in methotrexate-induced gastrointestinal toxicity [J]. Surgery 2001, 130(5):859-865.
21. Song WB, Wang YY, Meng FS, et al. Curcumin protects intestinal mucosal barrier function of rat enteritis via activation of MKP-1 and attenuation of p38 and NF-kappaB activation [J]. PLoS One 2010, 5(9):e12969.
22. Kimura T, Fujiyama Y, Sasaki M, et al. The role of mucosal mast cell degranulation and free-radical generation in intestinal ischaemia-reperfusion injury in rats [J]. Eur J Gastroenterol Hepatol 1998, 10(8):659-666.
23. Grisham MB, Hernandez LA, Granger DN Xanthine oxidase and neutrophil infiltration in intestinal ischemia [J]. Am J Physiol 1986, 251(4 Pt 1):G567-G574.
24. Cheon JH, Kim JS, Kim JM, et al. Plant sterol guggulsterone inhibits nuclear factor-kappa B signaling in intestinal epithelial cells by blocking IkappaB kinase and ameliorates acute murine colitis [J]. Inflamm Bowel Dis 2006, 12(12):1152-1161.
25. Tibble JA, Sigthorsson G, Bridger S, et al. Surrogate markers of intestinal inflammation are predictive of relapse in patients with inflammatory bowel disease [J]. Gastroenterology 2000, 119(1):15-22.
26. Sener G, Eksioglu-Demiralp E, Cetiner M, et al. L-Carnitine ameliorates methotrexate-induced oxidative organ injury and inhibits leukocyte death [J]. Cell Biol Toxicol 2006, 22(1):47-60.
27. Hileman EA, Achanta G, Huang P Superoxide dismutase: an emerging target for cancer therapeutics [J]. Expert Opin Ther Targets 2001, 5(6):697-710.
28. Rezaei-Moghadam A, Mohajeri D, Rafiei B, et al. Effect of turmeric and carrot seed extracts on serum liver biomarkers and hepatic lipid peroxidation, antioxidant enzymes and total antioxidant status in rats [J]. BioImpacts 2012, 2(3):151-157.