Cordyceps sinensis polysaccharide CPS-2 protects human mesangial cells from PDGF-BB-induced proliferation through the PDGF/ERK and TGF-β1/Smad pathways

Molecular and Cellular Endocrinology

Volumn 382, Issue 2, 2014, Pages 979-988

  Wang, Ying ^a   Liu, Dan ^a   Zhao, Huan ^a   Jiang, Huixing ^b   Luo, Chen ^a   Wang, Min ^a   Yin, Hongping ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Cordyceps sinensis; ERK; Mesangial cells; PDGF BB; Polysaccharide; TGF 1

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; ALPHA SMOOTH MUSCLE ACTIN; CORDYCEPS SINENSIS POLYSACCHARIDE; CPS 2; MITOGEN ACTIVATED PROTEIN KINASE; PLATELET DERIVED GROWTH FACTOR BB; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; POLYSACCHARIDE; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ARTICLE; CELL PROLIFERATION; CELL PROTECTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENTIATION; ENZYME ACTIVATION; ENZYME INHIBITION; GENE SILENCING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MESANGIUM CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

CORDYCEPS SINENSIS; ERK; MESANGIAL CELLS; PDGF-BB; POLYSACCHARIDE; TGF-Β1;

ACTINS; BUTADIENES; CELL PROLIFERATION; CELLS, CULTURED; CORDYCEPS; DRUG SYNERGISM; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FUNGAL POLYSACCHARIDES; GENE EXPRESSION REGULATION; HUMANS; MESANGIAL CELLS; NITRILES; PLATELET-DERIVED GROWTH FACTOR; PROTO-ONCOGENE PROTEINS C-SIS; SIGNAL TRANSDUCTION; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84890679385     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2013.11.018     Document Type: Article

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