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Volumn 85, Issue 1, 2014, Pages 11-17

The Nicotinic α5 Subunit Can Replace Either an Acetylcholine-Binding or Nonbinding Subunit in the α4β2* Neuronal Nicotinic Receptor

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR ALPHA4BETA2; NICOTINIC RECEPTOR ALPHA5; UNCLASSIFIED DRUG;

EID: 84890676531     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.113.089979     Document Type: Article
Times cited : (25)

References (23)
  • 3
    • 34548604495 scopus 로고    scopus 로고
    • Nicotinic a5 subunit deletion locally reduces high-affinity agonist activation without altering nicotinic receptor numbers
    • Brown RW, Collins AC, Lindstrom JM, and Whiteaker P (2007) Nicotinic a5 subunit deletion locally reduces high-affinity agonist activation without altering nicotinic receptor numbers. J Neurochem 103:204-215.
    • (2007) J Neurochem , vol.103 , pp. 204-215
    • Brown, R.W.1    Collins, A.C.2    Lindstrom, J.M.3    Whiteaker, P.4
  • 4
    • 67650589051 scopus 로고    scopus 로고
    • Pentameric concatenated (a4)( 2)(b2)(3) and (a4)(3)(b2)(2) nicotinic acetylcholine receptors subunit arrangement determines functional expression
    • Carbone AL, Moroni M, Groot-Kormelink PJ, and Bermudez I (2009) Pentameric concatenated (a4)(2)(b2)(3) and (a4)(3)(b2)(2) nicotinic acetylcholine receptors: Subunit arrangement determines functional expression. Br J Pharmacol 156: 970-981.
    • (2009) Br J Pharmacol , vol.156 , pp. 970-981
    • Carbone, A.L.1    Moroni, M.2    Groot-Kormelink, P.J.3    Bermudez, I.4
  • 5
    • 0036006697 scopus 로고    scopus 로고
    • Potentiation of human a4b2 neuronal nicotinic acetylcholine receptor by estradiol
    • Curtis L, Buisson B, Bertrand S, and Bertrand D (2002) Potentiation of human a4b2 neuronal nicotinic acetylcholine receptor by estradiol. Mol Pharmacol 61:127-135.
    • (2002) Mol Pharmacol , vol.61 , pp. 127-135
    • Curtis, L.1    Buisson, B.2    Bertrand, S.3    Bertrand, D.4
  • 6
    • 84857072852 scopus 로고    scopus 로고
    • Striatal a5 nicotinic receptor subunit regulates dopamine transmission in dorsal striatum
    • Exley R, McIntosh JM, Marks MJ, Maskos U, and Cragg SJ (2012) Striatal a5 nicotinic receptor subunit regulates dopamine transmission in dorsal striatum. J Neurosci 32:2352-2356.
    • (2012) J Neurosci , vol.32 , pp. 2352-2356
    • Exley, R.1    McIntosh, J.M.2    Marks, M.J.3    Maskos, U.4    Cragg, S.J.5
  • 8
    • 0031821563 scopus 로고    scopus 로고
    • A 5 Subunit alters desensitization, pharmacology, Ca11 permeability and Ca11 modulation of human neuronal a 3 nicotinic receptors
    • Gerzanich V, Wang F, Kuryatov A, and Lindstrom J (1998) a 5 Subunit alters desensitization, pharmacology, Ca11 permeability and Ca11 modulation of human neuronal a 3 nicotinic receptors. J Pharmacol Exp Ther 286:311-320.
    • (1998) J Pharmacol Exp Ther , vol.286 , pp. 311-320
    • Gerzanich, V.1    Wang, F.2    Kuryatov, A.3    Lindstrom, J.4
  • 10
    • 0034740035 scopus 로고    scopus 로고
    • Formation of functional a3b4a5 human neuronal nicotinic receptors in Xenopus oocytes: A reporter mutation approach
    • Groot-Kormelink PJ, Boorman JP, and Sivilotti LG (2001) Formation of functional a3b4a5 human neuronal nicotinic receptors in Xenopus oocytes: A reporter mutation approach. Br J Pharmacol 134:789-796.
    • (2001) Br J Pharmacol , vol.134 , pp. 789-796
    • Groot-Kormelink, P.J.1    Boorman, J.P.2    Sivilotti, L.G.3
  • 11
    • 79960953776 scopus 로고    scopus 로고
    • Unraveling the high-and low-sensitivity agonist responses of nicotinic acetylcholine receptors
    • Harpsøe K, Ahring PK, Christensen JK, Jensen ML, Peters D, and Balle T (2011) Unraveling the high-and low-sensitivity agonist responses of nicotinic acetylcholine receptors. J Neurosci 31:10759-10766.
    • (2011) J Neurosci , vol.31 , pp. 10759-10766
    • Harpsøe, K.1    Ahring, P.K.2    Christensen, J.K.3    Jensen, M.L.4    Peters, D.5    Balle, T.6
  • 12
    • 79955712436 scopus 로고    scopus 로고
    • A portable site: A binding element for 17b-estradiol can be placed on any subunit of a nicotinic a4b2 receptor
    • Jin X and Steinbach JH (2011) A portable site: A binding element for 17b-estradiol can be placed on any subunit of a nicotinic a4b2 receptor. J Neurosci 31: 5045-5054.
    • (2011) J Neurosci , vol.31 , pp. 5045-5054
    • Jin, X.1    Steinbach, J.H.2
  • 13
    • 33751097513 scopus 로고    scopus 로고
    • Role of the agonist binding site in up-regulation of neuronal nicotinic a4b2 receptors
    • Kishi M and Steinbach JH (2006) Role of the agonist binding site in up-regulation of neuronal nicotinic a4b2 receptors. Mol Pharmacol 70:2037-2044.
    • (2006) Mol Pharmacol , vol.70 , pp. 2037-2044
    • Kishi, M.1    Steinbach, J.H.2
  • 14
    • 45749094140 scopus 로고    scopus 로고
    • Roles of accessory subunits in a4b2(*) nicotinic receptors
    • Kuryatov A, Onksen J, and Lindstrom J (2008) Roles of accessory subunits in a4b2(*) nicotinic receptors. Mol Pharmacol 74:132-143.
    • (2008) Mol Pharmacol , vol.74 , pp. 132-143
    • Kuryatov, A.1    Onksen, J.2    Lindstrom, J.3
  • 15
    • 37349116624 scopus 로고    scopus 로고
    • The a4b2a5 nicotinic cholinergic receptor in rat brain is resistant to up-regulation by nicotine in vivo
    • Mao D, Perry DC, Yasuda RP, Wolfe BB, and Kellar KJ (2008) The a4b2a5 nicotinic cholinergic receptor in rat brain is resistant to up-regulation by nicotine in vivo. J Neurochem 104:446-456.
    • (2008) J Neurochem , vol.104 , pp. 446-456
    • Mao, D.1    Perry, D.C.2    Yasuda, R.P.3    Wolfe, B.B.4    Kellar, K.J.5
  • 16
    • 80052215644 scopus 로고    scopus 로고
    • Additional acetylcholine (ACh) binding site at a4/a4 interface of (a4b2)2a4 nicotinic receptor influences agonist sensitivity
    • Mazzaferro S, Benallegue N, Carbone A, Gasparri F, Vijayan R, Biggin PC, Moroni M, and Bermudez I (2011) Additional acetylcholine (ACh) binding site at a4/a4 interface of (a4b2)2a4 nicotinic receptor influences agonist sensitivity. J Biol Chem 286:31043-31054.
    • (2011) J Biol Chem , vol.286 , pp. 31043-31054
    • Mazzaferro, S.1    Benallegue, N.2    Carbone, A.3    Gasparri, F.4    Vijayan, R.5    Biggin, P.C.6    Moroni, M.7    Bermudez, I.8
  • 17
    • 33746238089 scopus 로고    scopus 로고
    • A4b2 nicotinic receptors with high and low acetylcholine sensitivity: Pharmacology, stoichiometry, and sensitivity to long-term exposure to nicotine
    • Moroni M, Zwart R, Sher E, Cassels BK, and Bermudez I (2006) a4b2 nicotinic receptors with high and low acetylcholine sensitivity: Pharmacology, stoichiometry, and sensitivity to long-term exposure to nicotine. Mol Pharmacol 70:755-768.
    • (2006) Mol Pharmacol , vol.70 , pp. 755-768
    • Moroni, M.1    Zwart, R.2    Sher, E.3    Cassels, B.K.4    Bermudez, I.5
  • 18
  • 19
    • 0035449919 scopus 로고    scopus 로고
    • The C terminus of the human nicotinic a4b2 receptor forms a binding site required for potentiation by an estrogenic steroid
    • Paradiso K, Zhang J, and Steinbach JH (2001) The C terminus of the human nicotinic a4b2 receptor forms a binding site required for potentiation by an estrogenic steroid. J Neurosci 21:6561-6568.
    • (2001) J Neurosci , vol.21 , pp. 6561-6568
    • Paradiso, K.1    Zhang, J.2    Steinbach, J.H.3
  • 22
    • 33744473099 scopus 로고    scopus 로고
    • 5-I A-85380 and TC-2559 differentially activate heterologously expressed a4b2 nicotinic receptors
    • Zwart R, Broad LM, Xi Q, Lee M, Moroni M, Bermudez I, and Sher E (2006) 5-I A-85380 and TC-2559 differentially activate heterologously expressed a4b2 nicotinic receptors. Eur J Pharmacol 539:10-17.
    • (2006) Eur J Pharmacol , vol.539 , pp. 10-17
    • Zwart, R.1    Broad, L.M.2    Xi, Q.3    Lee, M.4    Moroni, M.5    Bermudez, I.6    Sher, E.7
  • 23
    • 0030842275 scopus 로고    scopus 로고
    • Potentiation and inhibition of neuronal nicotinic receptors by atropine: Competitive and noncompetitive effects
    • Zwart R and Vijverberg HP (1997) Potentiation and inhibition of neuronal nicotinic receptors by atropine: Competitive and noncompetitive effects. Mol Pharmacol 52: 886-895.
    • (1997) Mol Pharmacol , vol.52 , pp. 886-895
    • Zwart, R.1    Vijverberg, H.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.