Latency can be conferred to a variety of cytokines by fusion with latency-associated peptide from TGF-β

Expert Opinion on Drug Delivery

Volumn 11, Issue 1, 2014, Pages 5-16

  Mullen, Lisa ^a   Rigby, Anne ^b   Sclanders, Michelle ^a   Adams, Gill ^a   Mittal, Gayatri ^a   Colston, Julia ^a   Fatah, Rewas ^a   Subang, Cristina ^a   Foster, Julie ^a   Francis West, Philippa ^c   Köster, Mario ^d   Hauser, Hansjörg ^d   Layward, Lorna ^a   Vessillier, Sandrine ^a   Annenkov, Alex ^a   Al Izki, Sarah ^a   Pryce, Gareth ^a   Bolton, Chris ^a   Baker, David ^a   Gould, David J ^a   Chernajovsky, Yuti ^a   more..

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

Author keywords

Bioassay; Cytokines; Latency associated peptide; Protein design; Targeted delivery

Indexed keywords

BETA INTERFERON; CYTOKINE; ERYTHROPOIETIN; HYBRID PROTEIN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 4; INTERSTITIAL COLLAGENASE; LATENCY ASSOCIATED PEPTIDE; OSTEOGENIC PROTEIN 1; SOMATOMEDIN C; TRANSFORMING GROWTH FACTOR BETA; LATENCY-ASSOCIATED PROPEPTIDE, TGF-BETA; PEPTIDE; PROTEIN PRECURSOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOASSAY; BIOLOGICAL ACTIVITY; CHEMICAL STRUCTURE; DISEASE COURSE; DRUG DELIVERY SYSTEM; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; HALF LIFE TIME; MOLECULAR SIZE; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN ENGINEERING; SPINAL CORD; TRANSIENT EXPRESSION; WESTERN BLOTTING; ANIMAL; CELL CULTURE; CELL LINE; CHICK EMBRYO; DBA MOUSE; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FIBROBLAST; GENETICS; HEK293 CELL LINE; HELA CELL LINE; HUMAN; METABOLISM; MINK; MOLECULARLY TARGETED THERAPY;

ANIMALS; CELL LINE; CELLS, CULTURED; CHICK EMBRYO; CYTOKINES; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FIBROBLASTS; HEK293 CELLS; HELA CELLS; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MATRIX METALLOPROTEINASE 1; MICE; MICE, INBRED DBA; MINK; MOLECULAR TARGETED THERAPY; PEPTIDES; PROTEIN PRECURSORS; RECOMBINANT FUSION PROTEINS; TRANSFORMING GROWTH FACTOR BETA;

EID: 84890611751     PISSN: 17425247     EISSN: 17447593     Source Type: Journal    
DOI: 10.1517/17425247.2013.839655     Document Type: Article

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