A failure in energy metabolism and antioxidant uptake precede symptoms of Huntington's disease in mice

Nature Communications

Volumn 4, Issue , 2013, Pages

  Acuña, Aníbal I ^a,b   Esparza, Magdalena ^a,b   Kramm, Carlos ^a,b   Beltrán, Felipe A ^a,b   Parra, Alejandra V ^a,b   Cepeda, Carlos ^c   Toro, Carlos A ^a   Vidal, René L ^d   Hetz, Claudio ^e   Concha, Ilona I ^a   Brauchi, Sebastián ^a,b   Levine, Michael S ^c   Castro, Maite A ^a,b  

^a UNIVERSIDAD AUSTRAL DE CHILE   (Chile)

^b Universidad Austral de Chile   (Chile)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CHILE   (Chile)

^e Millennium Nucleus for Regenerative Biology and Neurounion Biomedical Foundation   (Chile)

Author keywords

[No Author keywords available]

Indexed keywords

ASCORBIC ACID; ASCORBIC ACID TRANSPORTER 2; CARRIER PROTEIN; HUNTINGTIN; MUTANT PROTEIN; UNCLASSIFIED DRUG;

BRAIN; DISEASE INCIDENCE; MEMBRANE; METABOLISM; MUTATION; NEUROLOGY; PLASMA; RODENT; SYMPTOM;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BIOTINYLATION; CELL MEMBRANE; CONTROLLED STUDY; ENDOCYTOSIS; ENDOSOME; ENERGY METABOLISM; EXOCYTOSIS; FEMALE; HUNTINGTON CHOREA; INTRACELLULAR TRANSPORT; MOUSE; NERVE CELL; NONHUMAN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SYNAPTIC TRANSMISSION; WESTERN BLOTTING;

MUS;

ANIMALS; ASCORBIC ACID; ASTROCYTES; CELL LINE; CELL MEMBRANE; DISEASE MODELS, ANIMAL; ENERGY METABOLISM; FEMALE; HUNTINGTON DISEASE; MALE; MICE; MICE, TRANSGENIC; NERVE TISSUE PROTEINS; NEUROGLIA; NEURONS; PROTEIN TRANSPORT; RATS, WISTAR; SODIUM-COUPLED VITAMIN C TRANSPORTERS;

EID: 84890607414     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms3917     Document Type: Article

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