Rare mutations in renal sodium and potassium transporter genes exhibit impaired transport function

Current Opinion in Nephrology and Hypertension

Volumn 23, Issue 1, 2014, Pages 1-8

  Welling, Paul A ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

blood pressure; hypertension; kidney; loop diuretic; NKCC2 SLC12A1; ROMK KCNJ1 Kir1.1; salt; SLC12A3; thiazide

Indexed keywords

ALDOSTERONE; POTASSIUM CHANNEL; POTASSIUM CHANNEL KCNJ1; POTASSIUM CHANNEL KCNJ5; SODIUM CHLORIDE; SODIUM CHLORIDE COTRANSPORTER; SODIUM POTASSIUM CHLORIDE COTRANSPORTER; UNCLASSIFIED DRUG;

BINDING SITE; BLOOD PRESSURE VARIABILITY; CELL MIGRATION; CELL PROLIFERATION; CELL SURFACE; CHANNEL GATING; CHEMICAL ANALYSIS; ENDOPLASMIC RETICULUM; GENE EXPRESSION; GENE MUTATION; GOLGI COMPLEX; HYPERTENSION; ION TRANSPORT; MEMBRANE DEPOLARIZATION; MEMBRANE POTENTIAL; MOLECULE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN PROCESSING; REGULATORY MECHANISM; REVIEW; SECRETORY PATHWAY; SINGLE NUCLEOTIDE POLYMORPHISM; TRANSPORT KINETICS;

ANIMALS; BLOOD PRESSURE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; HYPERTENSION; ION TRANSPORT; KIDNEY; MEMBRANE TRANSPORT PROTEINS; MUTATION; PHENOTYPE; POTASSIUM; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RISK FACTORS; SODIUM; SOLUTE CARRIER FAMILY 12, MEMBER 1; SOLUTE CARRIER FAMILY 12, MEMBER 3;

EID: 84890564817     PISSN: 10624821     EISSN: 14736543     Source Type: Journal    
DOI: 10.1097/01.mnh.0000437204.84826.99     Document Type: Review

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