Time to say goodbye to the drug or the model? - Why do drugs fail to live up to their promise in bile duct ligated mice?

Journal of Hepatology

Volumn 60, Issue 1, 2014, Pages 12-15

  Fickert, Peter ^a  

^a MEDICAL UNIVERSITY OF GRAZ   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIHYDRO 2,4,6 TRIMETHYL 3,5 PYRIDINEDICARBOXYLIC ACID DIETHYL ESTER; BILE ACID; BILIRUBIN; CARBON TETRACHLORIDE; CELL NUCLEUS RECEPTOR; CHOLERETIC AGENT; GLUCURONOSYLTRANSFERASE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; MULTIDRUG RESISTANCE PROTEIN 2; MULTIDRUG RESISTANCE PROTEIN 3; MULTIDRUG RESISTANCE PROTEIN 4; OLTIPRAZ; PHOSPHOLIPID; URSODEOXYCHOLIC ACID;

ATTENUATION; BILE DUCT; BILE DUCT DISEASE; BILE DUCT LIGATION; BILE DUCT PRESSURE; BILE FLOW; BILIARY FIBROSIS; BILIARY TRACT DISEASE; CHOLESTASIS; COMMON BILE DUCT; DISEASE ASSOCIATION; DRUG EFFICACY; DRUG EXCRETION; DRUG METABOLISM; FLOW RATE; HUMAN; LIVER CELL; LIVER DISEASE; LIVER FIBROSIS; LIVER FUNCTION; LIVER INJURY; MOUSE; NICK END LABELING; NONALCOHOLIC FATTY LIVER; NONHUMAN; PATHOLOGY; PHENOTYPE; PORTAL HYPERTENSION; PRIMARY BILIARY CIRRHOSIS; PRIORITY JOURNAL; REVIEW; SCLEROSING CHOLANGITIS; WOUND HEALING; EDITORIAL; END STAGE LIVER DISEASE; LIVER FAILURE;

ANIMALS; CHOLESTASIS, EXTRAHEPATIC; MALE; PYRAZINES;

EID: 84890562897     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2013.09.019     Document Type: Editorial

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