Moderate hypothermia inhibits brain inflammation and attenuates stroke-induced immunodepression in rats

CNS Neuroscience and Therapeutics

Volumn 20, Issue 1, 2014, Pages 67-75

  Gu, Li Juan ^a,b   Xiong, Xiao Xing ^a   Ito, Takashi ^a   Lee, Jessica ^a   Xu, Bao Hui ^a   Krams, Sheri ^a   Steinberg, Gary K ^a   Zhao, Heng ^a  

^a STANFORD UNIVERSITY   (United States)

^b HANGZHOU NORMAL UNIVERSITY   (China)

Author keywords

Focal cerebral ischemia; Hypothermia; Immunodepression; Inflammation; Leukocytes

Indexed keywords

CD68 ANTIGEN; CYCLOOXYGENASE 2; GAMMA INTERFERON; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; MACROPHAGE INFLAMMATORY PROTEIN 2; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; BODY TEMPERATURE; CAROTID ARTERY OBSTRUCTION; CD4+ T LYMPHOCYTE; CEREBROVASCULAR ACCIDENT; COMMON CAROTID ARTERY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DELAYED HYPERSENSITIVITY; ENCEPHALITIS; FLOW CYTOMETRY; GENE EXPRESSION; HYPOTHERMIA; IMMUNE DEFICIENCY; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE PROLIFERATION; LYMPHOCYTIC INFILTRATION; MACROPHAGE; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MONOCYTE; MONONUCLEAR CELL; NONHUMAN; RAT; REAL TIME POLYMERASE CHAIN REACTION; SPLEEN; STROKE INDUCED IMMUNODEPRESSION;

FOCAL CEREBRAL ISCHEMIA; HYPOTHERMIA; IMMUNODEPRESSION; INFLAMMATION; LEUKOCYTES;

ANIMALS; BRAIN; CYTOKINES; ENCEPHALITIS; GENE EXPRESSION REGULATION; HYPOTHERMIA, INDUCED; IMMUNE TOLERANCE; INFARCTION, MIDDLE CEREBRAL ARTERY; LEUKOCYTES; LEUKOCYTES, MONONUCLEAR; MALE; NEUROIMMUNOMODULATION; RATS; RATS, SPRAGUE-DAWLEY; SPLEEN; STROKE; T-LYMPHOCYTES;

EID: 84890562599     PISSN: 17555930     EISSN: 17555949     Source Type: Journal    
DOI: 10.1111/cns.12160     Document Type: Article

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