RNA interference-mediated silencing of laminin receptor 1 (LR1) suppresses migration and invasion and down-regulates matrix metalloproteinase (MMP)-2 and MMP-9 in trophoblast cells: Implication in the pathogenesis of preeclampsia

Journal of Molecular Histology

Volumn 44, Issue 6, 2013, Pages 661-668

  Wang, Leilei ^a   Zhang, Dan ^b   Yu, Yang ^a   Guan, Hongbo ^a   Qiao, Chong ^a   Shang, Tao ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

^b Women and Infants Hospital of Shenyang   (China)

Author keywords

67 kDa laminin receptor 1; Matrix metalloproteinases; Preeclampsia; Tissue inhibitor of metalloproteinases; Trophoblast invasion

Indexed keywords

GELATINASE A; GELATINASE B; LAMININ BINDING PROTEIN; LAMININ RECEPTOR 1; MITOGEN ACTIVATED PROTEIN KINASE; SHORT HAIRPIN RNA; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; UNCLASSIFIED DRUG;

ARTICLE; CELL INVASION; CELL INVASION ASSAY; CELL MIGRATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; GENE EXPRESSION; GENE SILENCING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PATHOGENESIS; PLASMID; PREECLAMPSIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RNA INTERFERENCE; SUPERNATANT; TROPHOBLAST; WESTERN BLOTTING; WOUND HEALING; ZYMOGRAPHY;

CELL LINE; CELL MOVEMENT; FEMALE; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; GENE SILENCING; HUMANS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; PRE-ECLAMPSIA; PREGNANCY; RECEPTORS, LAMININ; RNA INTERFERENCE; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TISSUE INHIBITOR OF METALLOPROTEINASE-2; TROPHOBLASTS;

EID: 84890558310     PISSN: 15672379     EISSN: 15672387     Source Type: Journal    
DOI: 10.1007/s10735-013-9515-6     Document Type: Article

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