-
2
-
-
63549126247
-
The contribution of brca1 and brca2 to ovarian cancer
-
Ramus SJ, Gayther SA. The contribution of BRCA1 and BRCA2 to ovarian cancer. Mol Oncol. 2009;3(2):138-150.
-
(2009)
Mol Oncol.
, vol.3
, Issue.2
, pp. 138-150
-
-
Ramus, S.J.1
Gayther, S.A.2
-
3
-
-
0037080115
-
Effect of brca mutations on the length of survival in epithelial ovarian tumors
-
David YB, Chetrit A, Hirsh-Yechezkel G, et al. Effect of BRCA mutations on the length of survival in epithelial ovarian tumors. Journal of Clinical Oncology 2002;20(2):463-466.
-
(2002)
Journal of Clinical Oncology
, vol.20
, Issue.2
, pp. 463-466
-
-
David, Y.B.1
Chetrit, A.2
Hirsh-Yechezkel, G.3
-
4
-
-
80053950209
-
Association of brca1 and brca2 mutations with survival, chemotherapy sensitivity, and gene mutator phenotype in patients with ovarian cancer
-
Yang D, Khan S, Sun Y, et al. Association of BRCA1 and BRCA2 mutations with survival, chemotherapy sensitivity, and gene mutator phenotype in patients with ovarian cancer. JAMA. 2011;306(14):1557-1565.
-
(2011)
JAMA
, vol.306
, Issue.14
, pp. 1557-1565
-
-
Yang, D.1
Khan, S.2
Sun, Y.3
-
5
-
-
0034604716
-
The breast cancer susceptibility gene brca1 is required for subnuclear assembly of rad51 and survival following treatment with the dna cross-linking agent cisplatin
-
Bhattacharyya A, Ear US, Koller BH, et al. The breast cancer susceptibility gene BRCA1 is required for subnuclear assembly of Rad51 and survival following treatment with the DNA cross-linking agent cisplatin. J Biol Chem. 2000;275(31):23899-23903.
-
(2000)
J Biol Chem.
, vol.275
, Issue.31
, pp. 23899-23903
-
-
Bhattacharyya, A.1
Ear, U.S.2
Koller, B.H.3
-
6
-
-
34249946686
-
Abraxas and rap80 form a brca1 protein complex required for the dna damage response
-
Wang B, Matsuoka S, Ballif BA, et al. Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response. Science. 2007;316(5828):1194-1198.
-
(2007)
Science.
, vol.316
, Issue.5828
, pp. 1194-1198
-
-
Wang, B.1
Matsuoka, S.2
Ballif, B.A.3
-
7
-
-
0028073794
-
Brca1 mutations in primary breast and ovarian carcinomas
-
Futreal PA, Liu Q, Shattuck-Eidens D, et al. BRCA1 mutations in primary breast and ovarian carcinomas. Science. 1994;266(5182):120-122.
-
(1994)
Science.
, vol.266
, Issue.5182
, pp. 120-122
-
-
Futreal, P.A.1
Liu, Q.2
Shattuck-Eidens, D.3
-
8
-
-
77953424052
-
Somatic brca status in ovarian tumors
-
abstract 5528
-
Hennessy B TK, Carey MS, et al. Somatic BRCA status in ovarian tumors. J Clin Oncol. 2009;27 (Suppl):abstract 5528.
-
(2009)
J Clin Oncol.
, vol.27
, Issue.SUPPL.
-
-
Hennessy B, T.K.1
Carey, M.S.2
-
9
-
-
0037130885
-
Inactivation of brca1 and brca2 in ovarian cancer
-
Hilton JL, Geisler JP, Rathe JA, et al. Inactivation of BRCA1 and BRCA2 in ovarian cancer. J Natl Cancer Inst. 2002;94(18):1396-1406.
-
(2002)
J Natl Cancer Inst.
, vol.94
, Issue.18
, pp. 1396-1406
-
-
Hilton, J.L.1
Geisler, J.P.2
Rathe, J.A.3
-
10
-
-
0034307160
-
Brca1 promoter region hypermethylation in ovarian carcinoma: A population-based study
-
Baldwin RL, Nemeth E, Tran H, et al. BRCA1 promoter region hypermethylation in ovarian carcinoma: A population-based study. Cancer Res. 2000;60(19):5329-5333.
-
(2000)
Cancer Res.
, vol.60
, Issue.19
, pp. 5329-5333
-
-
Baldwin, R.L.1
Nemeth, E.2
Tran, H.3
-
11
-
-
0034607234
-
Promoter hypermethylation and brca1 inactivation in sporadic breast and ovarian tumors
-
Esteller M, Silva JM, Dominguez G, et al. Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors. J Natl Cancer Inst. 2000;92(7):564-569.
-
(2000)
J Natl Cancer Inst.
, vol.92
, Issue.7
, pp. 564-569
-
-
Esteller, M.1
Silva, J.M.2
Dominguez, G.3
-
12
-
-
0033580432
-
Methylation of the brca1 promoter region in sporadic breast and ovarian cancer: Correlation with disease characteristics
-
Catteau A, Harris WH, Xu CF, et al. Methylation of the BRCA1 promoter region in sporadic breast and ovarian cancer: correlation with disease characteristics. Oncogene. 1999;18(11):1957-1965.
-
(1999)
Oncogene.
, vol.18
, Issue.11
, pp. 1957-1965
-
-
Catteau, A.1
Harris, W.H.2
Xu, C.F.3
-
13
-
-
60149095444
-
Most mammalian mrnas are conserved targets of micrornas
-
Friedman RC, Farh KK, Burge CB, et al. Most mammalian mRNAs are conserved targets of microRNAs. Genome Res. 2009;19(1):92-105.
-
(2009)
Genome Res.
, vol.19
, Issue.1
, pp. 92-105
-
-
Friedman, R.C.1
Farh, K.K.2
Burge, C.B.3
-
14
-
-
78649663246
-
A microrna screen to identify modulators of sensitivity to bcl2 inhibitor abt-263 (navitoclax)
-
Lam LT, Lu X, Zhang H, et al. A microRNA screen to identify modulators of sensitivity to BCL2 inhibitor ABT-263 (navitoclax). Mol Cancer Ther. 2010;9(11):2943-2950.
-
(2010)
Mol Cancer Ther.
, vol.9
, Issue.11
, pp. 2943-2950
-
-
Lam, L.T.1
Lu, X.2
Zhang, H.3
-
15
-
-
34547791273
-
Regulation of the p27(kip1) tumor suppressor by mir-221 and mir-222 promotes cancer cell proliferation
-
le Sage C, Nagel R, Egan DA, et al. Regulation of the p27(Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation. EMBO J. 2007;26(15):3699-3708.
-
(2007)
EMBO J.
, vol.26
, Issue.15
, pp. 3699-3708
-
-
Le Sage, C.1
Nagel, R.2
Egan, D.A.3
-
16
-
-
17244373777
-
Targeting the dna repair defect in brca mutant cells as a therapeutic strategy
-
Farmer H, McCabe N, Lord CJ, et al. Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature. 2005;434(7035):917-921.
-
(2005)
Nature.
, vol.434
, Issue.7035
, pp. 917-921
-
-
Farmer, H.1
McCabe, N.2
Lord, C.J.3
-
17
-
-
77955039099
-
Oral poly(adp-ribose) polymerase inhibitor olaparib in patients with brca1 or brca2 mutations and recurrent ovarian cancer: A proof-of-concept trial
-
Audeh MW, Carmichael J, Penson RT, et al. Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: A proof-of-concept trial. Lancet. 2010;376(9737):245- 251.
-
(2010)
Lancet.
, vol.376
, Issue.9737
, pp. 245-251
-
-
Audeh, M.W.1
Carmichael, J.2
Penson, R.T.3
-
18
-
-
67650471685
-
Inhibition of poly(adp-ribose) polymerase in tumors from brca mutation carriers
-
Fong PC, Boss DS, Yap TA, et al. Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers. N Engl J Med. 2009;361(2):123-134.
-
(2009)
N Engl J Med.
, vol.361
, Issue.2
, pp. 123-134
-
-
Fong, P.C.1
Boss, D.S.2
Yap, T.A.3
-
19
-
-
84863804699
-
Microrna-375 targets aeg-1 in hepatocellular carcinoma and suppresses liver cancer cell growth in vitro and in vivo
-
He XX, Chang Y, Meng FY, et al. MicroRNA-375 targets AEG-1 in hepatocellular carcinoma and suppresses liver cancer cell growth in vitro and in vivo. Oncogene. 2012;31(28):3357-3369.
-
(2012)
Oncogene.
, vol.31
, Issue.28
, pp. 3357-3369
-
-
He, X.X.1
Chang, Y.2
Meng, F.Y.3
-
20
-
-
80155174280
-
Breast cancer 1 (brca1) protein expression as a prognostic marker in sporadic epithelial ovarian carcinoma: An ncic ctg ov.16 correlative study
-
Weberpals JI, Tu D, Squire JA, et al. Breast cancer 1 (BRCA1) protein expression as a prognostic marker in sporadic epithelial ovarian carcinoma: An NCIC CTG OV.16 correlative study. Ann Oncol. 2011; 22(11):2403-2410.
-
(2011)
Ann Oncol.
, vol.22
, Issue.11
, pp. 2403-2410
-
-
Weberpals, J.I.1
Tu, D.2
Squire, J.A.3
-
21
-
-
30944436435
-
Prognostic factors in ovarian carcinoma stage iii patients. Can biomarkers improve the prediction of shortand long-Term survivors?
-
Kaern J, Aghmesheh M, Nesland JM, et al. Prognostic factors in ovarian carcinoma stage III patients. Can biomarkers improve the prediction of shortand long-Term survivors? Intl J Gynecol Cancer. 2005;15(6):1014-1022.
-
(2005)
Intl J Gynecol Cancer.
, vol.15
, Issue.6
, pp. 1014-1022
-
-
Kaern, J.1
Aghmesheh, M.2
Nesland, J.M.3
-
22
-
-
33645359491
-
Brca1 expression in a large series of sporadic ovarian carcinomas: A gynecologic oncology group study
-
Thrall M, Gallion HH, Kryscio R, et al. BRCA1 expression in a large series of sporadic ovarian carcinomas: A Gynecologic Oncology Group study. Int J Gynecol Cancer. 2006;16(Suppl 1):166-171.
-
(2006)
Int J Gynecol Cancer.
, vol.16
, Issue.SUPPL. 1
, pp. 166-171
-
-
Thrall, M.1
Gallion, H.H.2
Kryscio, R.3
-
23
-
-
70350048828
-
Methylation and protein expression of dna repair genes: Association with chemotherapy exposure and survival in sporadic ovarian and peritoneal carcinomas
-
Swisher EM, Gonzalez RM, Taniguchi T, et al. Methylation and protein expression of DNA repair genes: Association with chemotherapy exposure and survival in sporadic ovarian and peritoneal carcinomas. Mol Cancer. 2009;8:48.
-
(2009)
Mol Cancer
, vol.8
, pp. 48
-
-
Swisher, E.M.1
Gonzalez, R.M.2
Taniguchi, T.3
-
24
-
-
84857475389
-
Loss of brca1 protein expression as indicator of the brcaness phenotype is associated with favorable overall survival after complete resection of sporadic ovarian cancer
-
Radosa MP, Hafner N, Camara O, et al. Loss of BRCA1 protein expression as indicator of the BRCAness phenotype is associated with favorable overall survival after complete resection of sporadic ovarian cancer. Int J Gynecol Cancer. 2011;21(8):1399-1406.
-
(2011)
Int J Gynecol Cancer.
, vol.21
, Issue.8
, pp. 1399-1406
-
-
Radosa, M.P.1
Hafner, N.2
Camara, O.3
-
25
-
-
19544374106
-
A study on the expression of brca1 & p53 and their correlation in epithelial ovarian cancer
-
Yu M, Hao J, Jiao Z. A study on the expression of BRCA1 & P53 and their correlation in epithelial ovarian cancer. Chinese J Clin Oncol. 2005;32(1):18-20.
-
(2005)
Chinese J Clin Oncol.
, vol.32
, Issue.1
, pp. 18-20
-
-
Yu, M.1
Hao, J.2
Jiao, Z.3
-
26
-
-
81155133676
-
Brca1 is both a prognostic and predictive biomarker of response to chemotherapy in sporadic epithelial ovarian cancer
-
Carser JE, Quinn JE, Michie CO, et al. BRCA1 is both a prognostic and predictive biomarker of response to chemotherapy in sporadic epithelial ovarian cancer. Gynecol Oncol. 2011;123(3):492-498.
-
(2011)
Gynecol Oncol.
, vol.123
, Issue.3
, pp. 492-498
-
-
Carser, J.E.1
Quinn, J.E.2
Michie, C.O.3
-
27
-
-
33847005066
-
Prevalence of brca1 expression in epithelial ovarian cancer: Immunohistochemical study
-
Sirisabya N, Manchana T, Termrungreunglert W, et al. Prevalence of BRCA1 expression in epithelial ovarian cancer: immunohistochemical study. J Med Assoc Thailand. 2007;90(1):9-14.
-
(2007)
J Med Assoc Thailand.
, vol.90
, Issue.1
, pp. 9-14
-
-
Sirisabya, N.1
Manchana, T.2
Termrungreunglert, W.3
-
28
-
-
33646574585
-
Brca1 promoter methylation predicts adverse ovarian cancer prognosis
-
Chiang JW, Karlan BY, Cass L, et al. BRCA1 promoter methylation predicts adverse ovarian cancer prognosis. Gynecol Oncol. 2006;101(3):403-410.
-
(2006)
Gynecol Oncol.
, vol.101
, Issue.3
, pp. 403-410
-
-
Chiang, J.W.1
Karlan, B.Y.2
Cass, L.3
-
29
-
-
59149091637
-
Microrna regulation of dna repair gene expression in hypoxic stress
-
Crosby ME, Kulshreshtha R, Ivan M, et al. MicroRNA regulation of DNA repair gene expression in hypoxic stress. Cancer Res. 2009;69(3):1221-1229.
-
(2009)
Cancer Res.
, vol.69
, Issue.3
, pp. 1221-1229
-
-
Crosby, M.E.1
Kulshreshtha, R.2
Ivan, M.3
-
30
-
-
79955575393
-
Down-regulation of brca1 expression by mir-146a and mir-146b-5p in triple negative sporadic breast cancers
-
Garcia AI, Buisson M, Bertrand P, et al. Down-regulation of BRCA1 expression by miR-146a and miR-146b-5p in triple negative sporadic breast cancers. EMBO Mol Med. 2011;3(5):279-290.
-
(2011)
EMBO Mol Med.
, vol.3
, Issue.5
, pp. 279-290
-
-
Garcia, A.I.1
Buisson, M.2
Bertrand, P.3
-
31
-
-
0038147067
-
Brca1 expression modulates chemosensitivity of brca1-defective hcc1937 human breast cancer cells
-
Tassone P, Tagliaferri P, Perricelli A, et al. BRCA1 expression modulates chemosensitivity of BRCA1-defective HCC1937 human breast cancer cells. Br J Cancer. 2003;88(8):1285-1291.
-
(2003)
Br J Cancer.
, vol.88
, Issue.8
, pp. 1285-1291
-
-
Tassone, P.1
Tagliaferri, P.2
Perricelli, A.3
-
32
-
-
84867026675
-
Brca1 expression is an important biomarker for chemosensitivity: Suppression of brca1 increases the apoptosis via up-regulation of p53 and p21 during cisplatin treatment in ovarian cancer cells
-
Horiuchi A, Wang C, Kikuchi N, et al. BRCA1 expression is an important biomarker for chemosensitivity: suppression of BRCA1 increases the apoptosis via up-regulation of p53 and p21 during cisplatin treatment in ovarian cancer cells. Biomark Insights. 2007;1:49-59.
-
(2007)
Biomark Insights.
, vol.1
, pp. 49-59
-
-
Horiuchi, A.1
Wang, C.2
Kikuchi, N.3
-
33
-
-
0038031592
-
Role of brca1 in cellular resistance to paclitaxel and ionizing radiation in an ovarian cancer cell line carrying a defective brca1
-
Zhou C, Smith JL, Liu J. Role of BRCA1 in cellular resistance to paclitaxel and ionizing radiation in an ovarian cancer cell line carrying a defective BRCA1. Oncogene. 2003;22(16):2396-2404.
-
(2003)
Oncogene.
, vol.22
, Issue.16
, pp. 2396-2404
-
-
Zhou, C.1
Smith, J.L.2
Liu, J.3
-
34
-
-
0036546218
-
Dominant-negative activity of a brca1 truncation mutant: Effects on proliferation, tumorigenicity in vivo, and chemosensitivity in a mouse ovarian cancer cell line
-
Sylvain V, Lafarge S, Bignon YJ. Dominant-negative activity of a Brca1 truncation mutant: effects on proliferation, tumorigenicity in vivo, and chemosensitivity in a mouse ovarian cancer cell line. Int J Oncol. 2002;20(4):845-853.
-
(2002)
Int J Oncol.
, vol.20
, Issue.4
, pp. 845-853
-
-
Sylvain, V.1
Lafarge, S.2
Bignon, Y.J.3
-
35
-
-
80051736673
-
Real-Time pcr-based analysis of the human bile micrornaome identifies mir-9 as a potential diagnostic biomarker for biliary tract cancer
-
Shigehara K, Yokomuro S, Ishibashi O, et al. Real-Time PCR-based analysis of the human bile microRNAome identifies miR-9 as a potential diagnostic biomarker for biliary tract cancer. PLoS One. 2011;6(8):e23584.
-
(2011)
PLoS One
, vol.6
, Issue.8
-
-
Shigehara, K.1
Yokomuro, S.2
Ishibashi, O.3
-
36
-
-
77649275464
-
Mir-9, a myc/mycn-Activated microrna, regulates e-cadherin and cancer metastasis
-
Ma L, Young J, Prabhala H, et al. miR-9, a MYC/MYCN-Activated microRNA, regulates E-cadherin and cancer metastasis. Nat Cell Biol. 2010;12(3):247-256.
-
(2010)
Nat Cell Biol.
, vol.12
, Issue.3
, pp. 247-256
-
-
Ma, L.1
Young, J.2
Prabhala, H.3
-
37
-
-
84863790390
-
Microrna-9 up-regulation is involved in colorectal cancer metastasis via promoting cell motility
-
Zhu L, Chen H, Zhou D, et al. MicroRNA-9 up-regulation is involved in colorectal cancer metastasis via promoting cell motility. Med Oncol. 2012; 29(2):1037-1043.
-
(2012)
Med Oncol.
, vol.29
, Issue.2
, pp. 1037-1043
-
-
Zhu, L.1
Chen, H.2
Zhou, D.3
-
38
-
-
66949150988
-
Mir-92b and mir-9/9. Are specifically expressed in brain primary tumors and can be used to differentiate primary from metastatic brain tumors
-
Nass D, Rosenwald S, Meiri E, et al. MiR-92b and miR-9/9. are specifically expressed in brain primary tumors and can be used to differentiate primary from metastatic brain tumors. Brain Pathol. 2009;19(3):375-383.
-
(2009)
Brain Pathol.
, vol.19
, Issue.3
, pp. 375-383
-
-
Nass, D.1
Rosenwald, S.2
Meiri, E.3
-
39
-
-
43949136141
-
Potential role of mir-9 and mir-223 in recurrent ovarian cancer
-
Laios A, O'Toole S, Flavin R, et al. Potential role of miR-9 and miR-223 in recurrent ovarian cancer. Mol Cancer. 2008;7:35.
-
(2008)
Mol Cancer
, vol.7
, pp. 35
-
-
Laios, A.1
O'Toole, S.2
Flavin, R.3
-
40
-
-
10944251591
-
Repair and genetic consequences of endogenous dna base damage in mammalian cells
-
Barnes DE, Lindahl T. Repair and genetic consequences of endogenous DNA base damage in mammalian cells. Annu Rev Genet. 2004; 38:445-476.
-
(2004)
Annu Rev Genet.
, vol.38
, pp. 445-476
-
-
Barnes, D.E.1
Lindahl, T.2
-
41
-
-
49249119415
-
A synthetic lethal therapeutic approach: Poly(adp) ribose polymerase inhibitors for the treatment of cancers deficient in dna double-strand break repair
-
Ashworth A. A synthetic lethal therapeutic approach: poly(ADP) ribose polymerase inhibitors for the treatment of cancers deficient in DNA double-strand break repair. J Clin Oncol. 2008;26(22):3785-3790.
-
(2008)
J Clin Oncol.
, vol.26
, Issue.22
, pp. 3785-3790
-
-
Ashworth, A.1
-
42
-
-
80052389761
-
Olaparib in patients with recurrent high-grade serous or poorly differentiated ovarian carcinoma or triple-negative breast cancer: A phase 2, multicentre, open-label, nonrandomised study
-
Gelmon KA, Tischkowitz M, Mackay H, et al. Olaparib in patients with recurrent high-grade serous or poorly differentiated ovarian carcinoma or triple-negative breast cancer: A phase 2, multicentre, open-label, nonrandomised study. Lancet Oncol. 2011;12(9):852-861.
-
(2011)
Lancet Oncol.
, vol.12
, Issue.9
, pp. 852-861
-
-
Gelmon, K.A.1
Tischkowitz, M.2
Mackay, H.3
-
43
-
-
79960150694
-
Compromised cdk1 activity sensitizes brca-proficient cancers to parp inhibition
-
Johnson N, Li YC, Walton ZE, et al. Compromised CDK1 activity sensitizes BRCA-proficient cancers to PARP inhibition. Nat Med. 2011;17(7):875-882.
-
(2011)
Nat Med.
, vol.17
, Issue.7
, pp. 875-882
-
-
Johnson, N.1
Li, Y.C.2
Walton, Z.E.3
|