Glycosylation characterization of recombinant human erythropoietin produced in glycoengineered Pichia pastoris by mass spectrometry

Journal of Mass Spectrometry

Volumn 48, Issue 12, 2013, Pages 1308-1317

  Gong, Bing ^a   Burnina, Irina ^a   Stadheim, Terrance A ^a   Li, Huijuan ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

mass spectrometry; N linked glycosylation; O linked glycosylation; Pichia pastoris; rhEPO

Indexed keywords

CHINESE HAMSTER OVARY; GLYCOENGINEERED PICHIA PASTORIS; MASS SPECTROMETRIC ANALYSIS; N-LINKED GLYCOSYLATION; O-LINKED; PICHIA PASTORIS; RECOMBINANT HUMAN EPO; RHEPO;

GLYCOSYLATION; MASS SPECTROMETRY; POLYSACCHARIDES; YEAST;

ESTERIFICATION;

RECOMBINANT ERYTHROPOIETIN;

ANIMAL CELL; ARTICLE; COLLISIONALLY ACTIVATED DISSOCIATION; ELECTROSPRAY; GENETIC ENGINEERING; GLYCOSYLATION; MASS SPECTROMETRY; NONHUMAN; PEPTIDE MAPPING; PICHIA PASTORIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ENGINEERING; PROTEIN EXPRESSION; SIALYLATION;

MASS SPECTROMETRY; N-LINKED GLYCOSYLATION; O-LINKED GLYCOSYLATION; PICHIA PASTORIS; RHEPO;

ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; ERYTHROPOIETIN; HUMANS; METABOLIC ENGINEERING; PICHIA; RECOMBINANT PROTEINS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 84890517373     PISSN: 10765174     EISSN: 10969888     Source Type: Journal    
DOI: 10.1002/jms.3291     Document Type: Article

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