Juliprosopine and juliprosine from Prosopis juliflora leaves induce mitochondrial damage and cytoplasmic vacuolation on cocultured glial cells and neurons

Chemical Research in Toxicology

Volumn 26, Issue 12, 2013, Pages 1810-1820

  Silva, Victor Diogenes A ^a   Pitanga, Bruno P S ^a   Nascimento, Ravena P ^a   Souza, Cleide S ^a   Coelho, Paulo Lucas C ^a   Menezes Filho, Noélio ^a   Silva, André Mário M ^a   Costa, Maria De Fátima D ^a   El Bachá, Ramon S ^a   Velozo, Eudes S ^a   Costa, Silvia L ^a  

^a FEDERAL UNIVERSITY OF BAHIA   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ACID PROTEIN; JULIPROSINE; JULIPROSOPINE; PIPERIDINE DERIVATIVE; PLANT EXTRACT; TOTAL ALKALOID EXTRACT; UNCLASSIFIED DRUG; ALKALOID; INDOLIZINE DERIVATIVE; JULIFLORINE;

ALKALOID FRACTION; ANIMAL CELL; ARTICLE; BRAIN CELL; CARBON NUCLEAR MAGNETIC RESONANCE; CELL VACUOLE; CELL VIABILITY; COCULTURE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; FRACTIONATION; GLIA CELL; HEMISPHERE; IC 50; IMMUNOCYTOCHEMISTRY; NERVE CELL; NONHUMAN; PLANT LEAF; PRIMARY CULTURE; PROSOPIS JULIFLORA; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; WISTAR RAT; ANIMAL; CELL CULTURE; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; CYTOPLASM; DOSE RESPONSE; DRUG EFFECTS; GLIA; ISOLATION AND PURIFICATION; MITOCHONDRION; PATHOLOGY; PROSOPIS; STRUCTURE ACTIVITY RELATION;

ALKALOIDS; ANIMALS; CELL SURVIVAL; CELLS, CULTURED; COCULTURE TECHNIQUES; CYTOPLASM; DOSE-RESPONSE RELATIONSHIP, DRUG; INDOLIZINES; MITOCHONDRIA; MOLECULAR STRUCTURE; NEUROGLIA; NEURONS; PLANT LEAVES; PROSOPIS; RATS; RATS, WISTAR; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84890516418     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx4001573     Document Type: Article

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