Cytoplasmic vacuolation in cultured rat astrocytes induced by an organophosphorus agent requires extracellular signal-regulated kinase activation

Toxicology and Applied Pharmacology

Volumn 193, Issue 3, 2003, Pages 383-392

  Isobe, Ichiro ^a   Maeno, Yoshitaka ^a   Nagao, Masataka ^a   Iwasa, Mineo ^a,b   Koyama, Hiroyoshi ^a   Seko Nakamura, Yoshimi ^a   Monma Ohtaki, Jun ^a  

^a NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

^b SEIJOH UNIVERSITY   (Japan)

Author keywords

Astrocyte; Extracellular signal regulated kinase; Organophosphorus agent; Signal transduction; Toxicity; Vacuolar degeneration

Indexed keywords

BIS(PINACOLYLMETHYL)PHOSPHONATE; CYCLOHEXIMIDE; DYE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; ORGANOPHOSPHORUS COMPOUND; PROTEIN SYNTHESIS INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ASTROCYTE; CELL ASSAY; CELL PROTECTION; CELL STRUCTURE; CELL VACUOLE; CONTROLLED STUDY; CYTOPLASM; EMBRYO; ENZYME ACTIVATION; MITOCHONDRION; NEUROLOGIC DISEASE; NONHUMAN; PROTEIN SYNTHESIS; RAT; STELLATE CELL; SYNTHESIS;

EID: 0348109484     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.taap.2003.08.010     Document Type: Article

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