Metabolomics reveal D-alanine: D-alanine ligase as the target of D-cycloserine in mycobacterium tuberculosis

ACS Medicinal Chemistry Letters

Volumn 4, Issue 12, 2013, Pages 1233-1237

  Prosser, Gareth A ^a   De Carvalho, Luiz P S ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

cycloserine; mechanism of action; metabolomics; peptidoglycan; Tuberculosis

Indexed keywords

ALANINE; CARBON 13; CYCLOSERINE; LIGASE; RACEMASE;

ARTICLE; DRUG TARGETING; GROWTH INHIBITION; METABOLOMICS; MOLECULARLY TARGETED THERAPY; MULTIDRUG RESISTANT TUBERCULOSIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; VALIDATION STUDY;

EID: 84890499902     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml400349n     Document Type: Article

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