A liquid chromatography-tandem mass spectrometry assay for Marfey's derivatives of l-Ala, d-Ala, and d-Ala-d-Ala: Application to the in vivo confirmation of alanine racemase as the target of cycloserine in Escherichia coli

Analytical Biochemistry

Volumn 396, Issue 1, 2010, Pages 1-7

  Jamindar, Darshan ^a   Gutheil, William G ^a  

^a UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

Author keywords

Alanine branch; Alanine racemase; Antibiotic; Cell wall; Cycloserine; LC MS MS; Marfey's reagent

Indexed keywords

AMINO ACIDS; ANTIBIOTICS; BIOCHEMISTRY; BIOSYNTHESIS; CELL MEMBRANES; CYTOLOGY; ESCHERICHIA COLI; MASS SPECTROMETRY; METABOLITES; REAGENTS;

ALANINE BRANCH; ALANINE RACEMASE; CELL WALLS; CYCLOSERINE; LC-MS/MS;

LIQUID CHROMATOGRAPHY;

ALANINE; AMPICILLIN; ANTIBIOTIC AGENT; ANTIINFECTIVE AGENT; CYCLOSERINE; FOSFOMYCIN; REAGENT;

ANALYTIC METHOD; ARTICLE; BACTERIAL CELL WALL; BIOSYNTHESIS; CHEMICAL STRUCTURE; CONTROLLED STUDY; DERIVATIZATION; DRUG TARGETING; ESCHERICHIA COLI; LIQUID CHROMATOGRAPHY; METABOLITE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; TANDEM MASS SPECTROMETRY;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 70449631038     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2009.09.006     Document Type: Article

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