Skraup/Doebner-von Miller Reaction

Name Reactions in Heterocyclic Chemistry

Volumn , Issue , 2005, Pages 488-494

  Hudson, Andrew ^a  

^a LIGAND PHARMACEUTICALS INC   (United States)

Author keywords

Camps; Droebner; Gould Jacobs; Isoquinolines; Pictet Hubert; Pomeranz Fritsch; Quinolines; Riehm

Indexed keywords

CAMPS; DROEBNER; GOULD-JACOBS; ISOQUINOLINES; PICTET-HUBERT; POMERANZ-FRITSCH; QUINOLINES; RIEHM;

EID: 84890473713     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/0471704156.ch9     Document Type: Chapter

References (24)

1. Skraup, Z. H. Ber. 1880, 13, 2086.
2. For a review see: [R] Manske, R. H. F.; Kulka, M. Org.React. 1953, 7, 80.
3. Doebner, O.; von Miller, W. Ber. Dtsch Chem. Ges. 1883, 16, 2464.
4. Choi, H-Y.; Lee, B. S.; Chi, D-Y.; Kim, D-J. Heterocycles, 1998, 48, 2647.
5. Bischler, A. Ber. Dtsch Chem. Ges. 1892, 25, 2864.
6. Eisch, J. J.; Dluzniewski, J. J. Org. Chem. 1989, 54, 1269.
7. Cohn, E. W. J. Am. Chem. Soc. 1930, 52, 3685.
8. Utermohlen, W. P. J. Org. Chem. 1943, 8, 544. Yields given include small amounts of the 3-ethyl-5-mefhyl substituted quinoline.
9. Leir, C. M. J. Org. Chem. 1977, 42, 911.
10. Oleynik, L.L.; Shteingarts, V. D. J. Fluorine Chem. 1998, 91, 25.
11. Fujiwara, H.; Kitagawa, K. Heterocycles 2000, 53, 409.
12. O' Neill, P. M.; Tingle, M. D.; Mahmud, R.; Storr, R. C; Ward, S. A.; Park, B. K. Bioorg. Med. Chem. Lett. 1995, 5,2309.
13. Boger, D. L.; Boyce, C. W. J. Org. Chem. 2000, 65, 4088.
14. Song, Z.; Mertzman, M.; Hughes, D. L. J. Heterocyclic Chem. 1993, 30, 17.
15. Sprecher, A-v.; Gerspacher, M.; Beck, A.; Kimmel, S.; Wiestner, H.; Anderson, G. P.; Niederhauser, U.; Subramanian, N.; Bray, M. A. Bioorg. Med. Chem. Lett. 1998, 8, 965.
16. Matsugi, M.; Tabusa, F.; Minamikawa, J. Tetrahedron Lett. 2000, 41, 8523.
17. Li, X.-G.; Cheng, X.; Zhou, Q.-L. Synth. Comm. 2002, 32, 2477.
18. Ranu, B. C; Hajra, A.; Dey, S. S.; Jana, U.; Tetrahedron 2003, 59, 813.
19. Johnson, J. V.; Rauckman, B. S.; Baccanali, D. P.; Roth, B. J. Med. Chem. 1989, 32, 1942.
20. Ku, Y-Y.; Grieme, T.; Raje, P.; Sharma, P.; Morton, H. E.; Rozema, M.; King, S. A. J. Org. Chem. 2003, 68, 3238.
21. Edwards, J. P.; West, S. J.; Marschke, K. B.; Mais, D. E.; Gottardis, M. M.; Jones, T. K. J. Med. Chem 1998, 41, 303.
22. Bender, R. H. W.; Edwards, P. J.; Jones, T. K. US Pat. 6, 093,825; Jul 25, 2000.
23. Walter, v-H.; Sauter, H.; Winker, T. Helvetica Chimica Acta, 1992, 75, 1274.
24. Theoclitou, M-E.; Robinson, L. A. Tetrahedron Lett. 2002, 43, 3907.