A practical and scaleable synthesis of A-224817.0, a novel nonsteroidal ligand for the glucocorticoid receptor

Journal of Organic Chemistry

Volumn 68, Issue 8, 2003, Pages 3238-3240

  Ku, Yi Yin ^a   Grieme, Tim ^a   Raje, Prasad ^a   Sharma, Padam ^a   Morton, Howard E ^a   Rozema, Mike ^a   King, Steve A ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLYLATION;

ALLYL RESINS; BENZENE; GLUCOSE; PURIFICATION; SILANES;

SYNTHESIS (CHEMICAL);

A 224817 0; ALCOHOL DERIVATIVE; ALLYLTRIMETHYLSILANE; BENZENE DERIVATIVE; GLUCOCORTICOID RECEPTOR; LACTIC ACID 2 NAPHTHYL ESTER; LIGAND; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; QUINOLINE; STEROID; UNCLASSIFIED DRUG;

ALLYLATION; ARTICLE; CHEMICAL REACTION; DRUG ISOLATION; DRUG PURIFICATION; DRUG SYNTHESIS; RACEMIC MIXTURE;

CATALYSIS; COMBINATORIAL CHEMISTRY TECHNIQUES; HETEROCYCLIC COMPOUNDS, 2-RING; INDICATORS AND REAGENTS; LIGANDS; MOLECULAR STRUCTURE; QUINOLINES; RECEPTORS, GLUCOCORTICOID; STEREOISOMERISM;

EID: 0037453555     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo0268613     Document Type: Article

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