Investigating the role of matrix components in protection of Burkholderia cepacia complex biofilms against tobramycin

Journal of Cystic Fibrosis

Volumn 13, Issue 1, 2014, Pages 56-62

  Messiaen, Anne Sophie ^a   Nelis, Hans ^a   Coenye, Tom ^a  

^a GHENT UNIVERSITY   (Belgium)

Author keywords

Biofilm; Burkholderia cepacia complex; Cepacian; Matrix; PNAG; Tobramycin

Indexed keywords

DORNASE ALFA; TOBRAMYCIN;

ARTICLE; BACTERICIDAL ACTIVITY; BURKHOLDERIA CENOCEPACIA; BURKHOLDERIA CEPACIA COMPLEX; BURKHOLDERIA METALLICA; DEGRADATION; IN VITRO STUDY; NONHUMAN;

BIOFILM; BURKHOLDERIA CEPACIA COMPLEX; CEPACIAN; MATRIX; PNAG; TOBRAMYCIN;

ANTI-BACTERIAL AGENTS; BETA-GLUCANS; BIOFILMS; BURKHOLDERIA CEPACIA; BURKHOLDERIA INFECTIONS; CYSTIC FIBROSIS; DNA, BACTERIAL; DRUG RESISTANCE, BACTERIAL; HUMANS; MICROBIAL SENSITIVITY TESTS; POLYSACCHARIDES, BACTERIAL; TOBRAMYCIN; VIRULENCE; VIRULENCE FACTORS;

EID: 84890436893     PISSN: 15691993     EISSN: 18735010     Source Type: Journal    
DOI: 10.1016/j.jcf.2013.07.004     Document Type: Article

References (30)

1. Murray T.S., Egan M., Kazmierczak B.I. Pseudomonas aeruginosa chronic colonization in cystic fibrosis patients. Curr Opin Pediatr Feb 2007, 19(1):83-88.
2. Lyczak J.B., Cannon C.L., Pier G.B. Lung infections associated with cystic fibrosis. Clin Microbiol Rev Apr 2002, 15(2):194-222.
3. Zlosnik J.E., Costa P.S., Brant R., Mori P.Y., Hird T.J., Fraenkel M.C., et al. Mucoid and nonmucoid Burkholderia cepacia complex bacteria in cystic fibrosis infections. Am J Respir Crit Care Med Jan 1 2011, 183(1):67-72.
4. Bylund J., Burgess L.A., Cescutti P., Ernst R.K., Speert D.P. Exopolysaccharides from Burkholderia cenocepacia inhibit neutrophil chemotaxis and scavenge reactive oxygen species. J Biol Chem Feb 3 2006, 281(5):2526-2532.
5. Cuzzi B., Cescutti P., Furlanis L., Lagatolla C., Sturiale L., Garozzo D., et al. Investigation of bacterial resistance to the immune system response: cepacian depolymerisation by reactive oxygen species. Innate Immun Aug 2012, 18(4):661-671.
6. Cescutti P., Cuzzi B., Herasimenka Y., Rizzo R. Structure of a novel exopolysaccharide produced by Burkholderia vietnamiensis, a cystic fibrosis opportunistic pathogen. Carbohydr Polym Apr 15 2013, 94(1):253-260.
7. Yakandawala N., Gawande P.V., LoVetri K., Cardona S.T., Romeo T., Nitz M., et al. Characterization of the poly-beta-1,6-N-acetylglucosamine polysaccharide component of Burkholderia biofilms. Appl Environ Microbiol Dec 2011, 77(23):8303-8309.
8. Whitchurch C.B., Tolker-Nielsen T., Ragas P.C., Mattick J.S. Extracellular DNA required for bacterial biofilm formation. Science Feb 22 2002, 295(5559):1487.
9. Izano E.A., Amarante M.A., Kher W.B., Kaplan J.B. Differential roles of poly-N-acetylglucosamine surface polysaccharide and extracellular DNA in Staphylococcus aureus and Staphylococcus epidermidis biofilms. Appl Environ Microbiol Jan 2008, 74(2):470-476.
10. Steinberger R.E., Holden P.A. Extracellular DNA in single- and multiple-species unsaturated biofilms. Appl Environ Microbiol Sep 2005, 71(9):5404-5410.
11. Kaplan J.B., LoVetri K., Cardona S.T., Madhyastha S., Sadovskaya I., Jabbouri S., et al. Recombinant human DNase I decreases biofilm and increases antimicrobial susceptibility in staphylococci. J Antibiot Feb 2012, 65(2):73-77.
12. Mulcahy H., Charron-Mazenod L., Lewenza S. Extracellular DNA chelates cations and induces antibiotic resistance in Pseudomonas aeruginosa biofilms. PLoS Pathog Nov 2008, 4(11):e1000213.
13. Johnson L., Horsman S.R., Charron-Mazenod L., Turnbull A.L., Mulcahy H., Surette M.G., et al. Extracellular DNA-induced antimicrobial peptide resistance in Salmonella enterica serovar Typhimurium. BMC Microbiol May 24 2013, 13(1):115.
14. Chiang W.C., Nilsson M., Jensen P.O., Hoiby N., Nielsen T.E., Givskov M., et al. Extracellular DNA shields against aminoglycosides in Pseudomonas aeruginosa biofilms. Antimicrob Agents Chemother May 2013, 57(5):2352-2361.
15. Anderson M.S., Garcia E.C., Cotter P.A. The Burkholderia bcpAIOB genes define unique classes of two-partner secretion and contact dependent growth inhibition systems. PLoS Genet Aug 2012, 8(8):e1002877.
16. Gueroult M., Picot D., Abi-Ghanem J., Hartmann B., Baaden M. How cations can assist DNase I in DNA binding and hydrolysis. PLoS Comput Biol 2010, 6(11):e1001000.
17. Peeters E., Nelis H.J., Coenye T. In vitro activity of ceftazidime, ciprofloxacin, meropenem, minocycline, tobramycin and trimethoprim/sulfamethoxazole against planktonic and sessile Burkholderia cepacia complex bacteria. J Antimicrob Chemother Oct 2009, 64(4):801-809.
18. Wagener J.S., Kupfer O. Dornase alfa (Pulmozyme). Curr Opin Pulm Med Nov 2012, 18(6):609-614.
19. Sanders N.N., Franckx H., De Boeck K., Haustraete J., De Smedt S.C., Demeester J. Role of magnesium in the failure of rhDNase therapy in patients with cystic fibrosis. Thorax Nov 2006, 61(11):962-968.
20. Tetz V.V., Tetz G.V. Effect of extracellular DNA destruction by DNase I on characteristics of forming biofilms. DNA Cell Biol Aug 2010, 29(8):399-405.
21. Hunt B.E., Weber A., Berger A., Ramsey B., Smith A.L. Macromolecular mechanisms of sputum inhibition of tobramycin activity. Antimicrob Agents Chemother Jan 1995, 39(1):34-39.
22. Goodman S.D., Obergfell K.P., Jurcisek J.A., Novotny L.A., Downey J.S., Ayala E.A., et al. Biofilms can be dispersed by focusing the immune system on a common family of bacterial nucleoid-associated proteins. Mucosal Immunol Nov 2011, 4(6):625-637.
23. Novotny L.A., Amer A.O., Brockson M.E., Goodman S.D., Bakaletz L.O. Structural stability of Burkholderia cenocepacia biofilms in reliant on eDNA structure and presence of a bacterial nucleic acid binding protein. PLoS One 2013, 8(6).
24. Cunha M.V., Sousa S.A., Leitao J.H., Moreira L.M., Videira P.A., Sa-Correia I. Studies on the involvement of the exopolysaccharide produced by cystic fibrosis-associated isolates of the Burkholderia cepacia complex in biofilm formation and in persistence of respiratory infections. J Clin Microbiol Jul 2004, 42(7):3052-3058.
25. Herasimenka Y., Cescutti P., Sampaio Noguera C.E., Ruggiero J.R., Urbani R., Impallomeni G., et al. Macromolecular properties of cepacian in water and in dimethylsulfoxide. Carbohydr Res Jan 14 2008, 343(1):81-89.
26. Ferreira A.S., Silva I.N., Oliveira V.H., Cunha R., Moreira L.M. Insights into the role of extracellular polysaccharides in Burkholderia adaptation to different environments. Front Cell Infect Microbiol 2011, 1:16.
27. Benincasa M., Mattiuzzo M., Herasimenka Y., Cescutti P., Rizzo R., Gennaro R. Activity of antimicrobial peptides in the presence of polysaccharides produced by pulmonary pathogens. J Pept Sci Sep 2009, 15(9):595-600.
28. Ferreira A.S., Leitao J.H., Silva I.N., Pinheiro P.F., Sousa S.A., Ramos C.G., et al. Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions. Appl Environ Microbiol Jan 2010, 76(2):441-450.
29. Cescutti P., Scussolin S., Herasimenka Y., Impallomeni G., Bicego M., Rizzo R. First report of a lyase for cepacian, the polysaccharide produced by Burkholderia cepacia complex bacteria. Biochem Biophys Res Commun Jan 20 2006, 339(3):821-826.
30. Beggs W.H., Andrews F.A. Role of ionic strength in salt antagonism of aminoglycoside action on Escherichia coli and Pseudomonas aeruginosa. J Infect Dis Nov 1976, 134(5):500-504.