Recombinant human DNase i decreases biofilm and increases antimicrobial susceptibility in staphylococci

Journal of Antibiotics

Volumn 65, Issue 2, 2012, Pages 73-77

  Kaplan, Jeffrey B ^a   Lovetri, Karen ^b   Cardona, Silvia T ^c   Madhyastha, Srinivasa ^b   Sadovskaya, Irina ^d   Jabbouri, Sad ^e   Izano, Era A ^a  

^a RUTGERS SCHOOL OF DENTAL MEDICINE   (United States)

^b Kane Biotech Inc   (Canada)

^c UNIVERSITY OF MANITOBA   (Canada)

^d UNIV LILLE   (France)

^e INSTITUT DE RECHERCHE POUR LE DÉVELOPPEMENT   (France)

Author keywords

biofilm; dispersin B; DNase; extracellular DNA; Staphylococcus

Indexed keywords

BIOCIDE; DORNASE ALFA; TOBRAMYCIN;

ANTIBIOTIC SENSITIVITY; ARTICLE; BIOFILM; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; DRUG EFFICACY; DRUG POTENTIATION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS; SURVIVAL RATE;

ANIMALS; ANTI-BACTERIAL AGENTS; BIOFILMS; CAENORHABDITIS ELEGANS; DEOXYRIBONUCLEASE I; ESCHERICHIA COLI PROTEINS; HUMANS; MICROBIAL SENSITIVITY TESTS; RECOMBINATION, GENETIC; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS; TOBRAMYCIN;

CAENORHABDITIS ELEGANS; NEMATODA; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS;

EID: 84857739601     PISSN: 00218820     EISSN: 18811469     Source Type: Journal    
DOI: 10.1038/ja.2011.113     Document Type: Article

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